April 17, 2020 4:05 PM from Gilang Andri Pratama 1809511023 to everyone:

selamat sore prof

April 17, 2020 4:05 PM from Annisafitri Lutviana to everyone:

Selamat sore prof

April 17, 2020 4:05 PM from harjono utama to everyone: sore semjua guys

April 17, 2020 4:05 PM from Siti Muayyanah to everyone: selamat sore
prof

April 17, 2020 4:05 PM from kevin tri tama to everyone: selamat sore
prof

April 17, 2020 4:05 PM from febyana sidabutar 1709511051 to everyone:

sore prof

April 17, 2020 4:06 PM from Zelia Ximenes to everyone: Selamat sore Prof

April 17, 2020 4:06 PM from 1809511043_I GEDE GALYES PRANADINATA to

everyone: selamat sore prof

April 17, 2020 4:06 PM from FEBRIANTI (1809511024) to everyone:

selamat sore prof

April 17, 2020 4:06 PM from Jireh Petra Slat to everyone: selamat sore
prof

April 17, 2020 4:06 PM from kevin tri tama to everyone: sehat prof

April 17, 2020 4:07 PM from 1809511114 - Brainna Kirayna Ginting to

everyone: Selamat sore, prof

April 17, 2020 4:08 PM from kevin tri tama to everyone: setuju

April 17, 2020 4:08 PM from Siti Muayyanah to everyone: setuju prof

April 17, 2020 4:08 PM from 1809511100_Nur Intan Wulan Yunita to

everyone: setuju prof

April 17, 2020 4:10 PM from Ketut Elok Sukardika 17017 A to everyone:
Aple mic of plis

April 17, 2020 4:11 PM from harjono utama to everyone: cancer : dulu
penyakit orang berusia diatas 50 tahun tapi sekarang merambah ke usia 30 th nan.
why?

April 17, 2020 4:11 PM from Ketut Elok Sukardika 17017 A to everyone:
Karena makanan prof

April 17, 2020 4:12 PM from harjono utama to everyone: makanan seperti
apa??

April 17, 2020 4:12 PM from Ahmad Rohmadhon Holifatullah to everyone:

kebanyakan makanan karsinogen ik

April 17, 2020 4:12 PM from 1709511112 - Ni Putu Permata Dewi Maheswari
to everyone: pola hidup
April 17, 2020 4:12 PM from 1709511112 - Ni Putu Permata Dewi Maheswari
to everyone: fast food

April 17, 2020 4:12 PM from Ketut Elok Sukardika 17017 A to everyone:
Makanan sekarang banyak mengandung zat pengawet

April 17, 2020 4:12 PM from RyanHabibi to everyone: lingkungan

April 17, 2020 4:12 PM from Siti Muayyanah to everyone: regenerasi

sel yang mulai melambat

April 17, 2020 4:12 PM from Annisafitri Lutviana to everyone:

terlalu sering menggunakan msg

April 17, 2020 4:12 PM from kevin tri tama to everyone: radiasi
telepon (?)

April 17, 2020 4:12 PM from Ahmad Rohmadhon Holifatullah to everyone:

genetika prof mungkin ? dari keturunan

April 17, 2020 4:13 PM from Ahmad Rohmadhon Holifatullah to everyone:

semakin menurun

April 17, 2020 4:13 PM from kevin tri tama to everyone: iya prof..
panas banget

April 17, 2020 4:13 PM from Annisafitri Lutviana to everyone: jelas

prof

April 17, 2020 4:13 PM from kevin tri tama to everyone: jelas prof

April 17, 2020 4:13 PM from 1809511043_I GEDE GALYES PRANADINATA to

everyone: jelas prof

April 17, 2020 4:13 PM from 1809511100_Nur Intan Wulan Yunita to

everyone: jelas prof

April 17, 2020 4:13 PM from FEBRIANTI (1809511024) to everyone: jelas

prof

April 17, 2020 4:14 PM from harjono utama to everyone: human genome
project : rahasia gen manusia, apapun penyakit atau hal hal jelek yang dibawa orang
itu/ hewan bisa terlacak

April 17, 2020 4:16 PM from harjono utama to everyone: personalised

medicine : kedokteran pribadi

April 17, 2020 4:17 PM from harjono utama to everyone: mengurusi pribadi
seseorang

April 17, 2020 4:18 PM from harjono utama to everyone: jika ada seorg
wanita membawa gen DM mau nikah dg cowok yang membawa gen hemofili? kira kira
anaknya akan bagaimana? cek genetika Mendel!!

April 17, 2020 4:19 PM from harjono utama to everyone: berap yang
berpeluang mendapat hemofili, berapa% berpeluang dapat DM, berapa % berpeluang
dapat DM dan hemofili serta berapa persen yang aman aman saja

April 17, 2020 4:20 PM from harjono utama to everyone: yang aman aman
saja itu bukan berarti aman secara genetik, anak anak itu bisa menjadi carrier
pembawa gen gen tersebut walau secar klinis sehat

April 17, 2020 4:21 PM from harjono utama to everyone: pribadi kita
diobok obok oleh biologi molekuler

April 17, 2020 4:22 PM from harjono utama to everyone: biologi mol
penyakit : biokimiawi (berbagai aspek biokimiawi)

April 17, 2020 4:23 PM from harjono utama to everyone: variasi mekanisme
kerja : mekanisme kerja berbagai bahan biokimiawi dalam tubuh manusia/ hewan

April 17, 2020 4:25 PM from harjono utama to everyone: nDNA : DNA inti
sel, mt DNA : DNA mitokondria. apa hubungan antara kedua kjenis DNA ini?

April 17, 2020 4:27 PM from harjono utama to everyone: house keepng gen :
gen pengelola sel/ maintenance sel

April 17, 2020 4:28 PM from harjono utama to everyone: memelihara sel
agar tidak kotor/ keracunan/ berantakan karena banyaknya metabolit di dala,m sel,
belum lagi radikal bebas

April 17, 2020 4:30 PM from harjono utama to everyone: ada macam macam
bahasa :

April 17, 2020 4:31 PM from harjono utama to everyone: non verbal :
biosemiotik?

April 17, 2020 4:31 PM from harjono utama to everyone: verbal semodel
oral

April 17, 2020 4:31 PM from RyanHabibi to everyone: studi tentang

tanda tanda

April 17, 2020 4:32 PM from Siti Muayyanah to everyone: birahi

April 17, 2020 4:32 PM from 1809511043_I GEDE GALYES PRANADINATA to

everyone: birahi prof

April 17, 2020 4:33 PM from Siti Muayyanah to everyone: baru prof

April 17, 2020 4:33 PM from RyanHabibi to everyone: 3A prof

April 17, 2020 4:34 PM from RyanHabibi to everyone: bisa prof

April 17, 2020 4:34 PM from Siti Muayyanah to everyone: bisa prof

April 17, 2020 4:34 PM from 1809511043_I GEDE GALYES PRANADINATA to

everyone: pake insting prof

April 17, 2020 4:34 PM from Ketut Elok Sukardika 17017 A to everyone:
Ekornya prof

April 17, 2020 4:34 PM from harjono utama to everyone: biosemiotik anjing
yang minta makan/ dikasihani sama yang mau nyerang. apa bedanya??

April 17, 2020 4:34 PM from RyanHabibi to everyone: gerak tubuhnya

seolah berkata
April 17, 2020 4:34 PM from Siti Muayyanah to everyone: kalo nyerang
biasanya langsung ngejar

April 17, 2020 4:35 PM from harjono utama to everyone: bahasa

matematika ??

April 17, 2020 4:35 PM from Siti Muayyanah to everyone: dua

April 17, 2020 4:35 PM from harjono utama to everyone: bahasa

matematika : universal

April 17, 2020 4:35 PM from harjono utama to everyone: dimana pun sama
artinya

April 17, 2020 4:36 PM from Ketut Elok Sukardika 17017 A to everyone:
Ngerti prof

April 17, 2020 4:36 PM from Siti Muayyanah to everyone: tahu prof

April 17, 2020 4:36 PM from Marissa Divia to everyone: ngerti prof

April 17, 2020 4:36 PM from harjono utama to everyone: simbol simbol :
akar 4,

April 17, 2020 4:36 PM from 1809511114 - Brainna Kirayna Ginting to

everyone: Ngerti prof

April 17, 2020 4:36 PM from Ketut Elok Sukardika 17017 A to everyone:
Karena bahasa matematika sama di selur dunia

April 17, 2020 4:37 PM from harjono utama to everyone: kira kira suku
suku bangsa paham enggak dg simbol simbol diatas??

April 17, 2020 4:38 PM from harjono utama to everyone: bahasa sandi
genetika : bahasa baru yang walau sudah tidak baru (ditemukan tahn 1966 an)

April 17, 2020 4:38 PM from harjono utama to everyone: kenapa bahasa
baru?? ternyata dari sini bisa dibuat kode/ sandi matematika

April 17, 2020 4:39 PM from harjono utama to everyone: bahasa genetika :
ACGTU

April 17, 2020 4:41 PM from harjono utama to everyone: pre mRNA : RNA
massenger yang masih mentah

April 17, 2020 4:41 PM from harjono utama to everyone: perlu diolah lagi
sehingga menjadi matang (siap ditranslasi)

April 17, 2020 4:42 PM from harjono utama to everyone: dengan cara
membuang intron intron (blok kuning dan menggabung exon exon warna hijau) sehingga
siap ditranslasikan menjadi protein

April 17, 2020 4:44 PM from harjono utama to everyone: penambahan Poly(A)
bertujuan agar : proses transkripsi terhenti dan mRNA aman dari serangan RNA
nuklease

April 17, 2020 4:44 PM from harjono utama to everyone: setelah aman baru
siap ditranslasikan jadi protein
April 17, 2020 4:44 PM from kevin tri tama to everyone: sudah prof

April 17, 2020 4:45 PM from Ketut Elok Sukardika 17017 A to everyone:
Sudah prof

April 17, 2020 4:45 PM from Siti Muayyanah to everyone: siap prof

April 17, 2020 4:46 PM from harjono utama to everyone: G1 menjadi S :

tahap persiapan pembelahan sel : apakah DNA mu sudah siap sel??

April 17, 2020 4:47 PM from harjono utama to everyone: G2 : apakah DNA mu
sudah lengkap untuk direplikasi??

April 17, 2020 4:48 PM from harjono utama to everyone: metafase anafase :
apakah kromosom sudah siap di aligned (dipadankan) di ekuator kromosom??

April 17, 2020 4:48 PM from harjono utama to everyone: akibat dari G1
sampai Metafase anafase : sel harus memutuskan apakah semua sdh siap termasuk
penataan kromosomnya??

April 17, 2020 4:49 PM from harjono utama to everyone: akibat persiapan
pengambilan keputusan ini : sel bisa membelah, istirahat atau mati/ apoptosis

April 17, 2020 4:50 PM from Siti Muayyanah to everyone: paham prof

April 17, 2020 4:50 PM from Ahmad Rohmadhon Holifatullah to everyone:

pun prof

April 17, 2020 4:50 PM from Ahmad Rohmadhon Holifatullah to everyone:

paham

April 17, 2020 4:50 PM from RyanHabibi to everyone: baik prof

April 17, 2020 4:50 PM from Ketut Elok Sukardika 17017 A to everyone:
Iya prof

April 17, 2020 4:50 PM from 1809511043_I GEDE GALYES PRANADINATA to

everyone: ashiap prof

April 17, 2020 4:50 PM from Siti Muayyanah to everyone: baik prof

April 17, 2020 4:51 PM from 1809511043_I GEDE GALYES PRANADINATA to

everyone: tidak prof

April 17, 2020 4:52 PM from harjono utama to everyone: p53 : terkait
dengan masalah regulasi cancer

April 17, 2020 4:53 PM from 1809511043_I GEDE GALYES PRANADINATA to

everyone: tugas saja prof

April 17, 2020 4:53 PM from Ahmad Rohmadhon Holifatullah to everyone:

tugss

April 17, 2020 4:53 PM from Ketut Elok Sukardika 17017 A to everyone:
Tugas

April 17, 2020 4:53 PM from kevin tri tama to everyone: tugas prof

April 17, 2020 4:53 PM from harjono utama to everyone: cari lain
lainnya : p21; CDK2 dll yang terpampang disini, apakah itu??

April 17, 2020 4:53 PM from 1809511127_Wafiq Annisa to everyone: tugas

prof

April 17, 2020 4:53 PM from kevin tri tama to everyone: yakinnnnn

April 17, 2020 4:53 PM from FEBRIANTI (1809511024) to everyone: tugas

prof

April 17, 2020 4:55 PM from FEBRIANTI (1809511024) to everyone: maaf

prof izin bertanya: hubungan antara ekson & intron dengan siklus DNA damage ini apa
prof?

April 17, 2020 4:55 PM from kevin tri tama to everyone: luar

April 17, 2020 4:55 PM from harjono utama to everyone: Epi genetik : dari
DNA sampai RNA lengkap dan aman

April 17, 2020 4:56 PM from harjono utama to everyone: terjadinya di

nukleus (epigenetik)

April 17, 2020 4:59 PM from harjono utama to everyone: mRNA yang sudah
diamankan akan keluar dari nti sel dan masuk ke sitoplasma. Di sitoplasma banyak
RNA nuklease (enzim pemecah RNA). tapi karena molekul RNA tadi telah diperlengkapi
oleh poly(A) maka dia aman aman aja

April 17, 2020 5:00 PM from harjono utama to everyone: di sitoplasma juga
RNA tadi akan menjadi sumber informasi yang perlu diterjemahkan (karena ini penting
dari nukleotida menjadi asam amino). menerjemahkan bahasa dari nukleotida ke asam
amino itulah bahasa gentika yang didepan tadi.

April 17, 2020 5:01 PM from kevin tri tama to everyone: paham
prof...

April 17, 2020 5:01 PM from kevin tri tama to everyone: yang tRNA
gitu kan?

April 17, 2020 5:02 PM from harjono utama to everyone: mRNA juga jika
sudah diambil informasinya maka dia akan siap didegradasi (lihat point 5 yang
dilimngkari merah). artinya akan dihancurkan oleh sel dan nukleotidanya
diselamatkan (ingat kuliah biokimia 2 mengenai metabolisme asam nukleat).

April 17, 2020 5:02 PM from harjono utama to everyone: sumber informasi
ada di butir 4 yang dilingkari merah. inilah genetika itu

April 17, 2020 5:02 PM from harjono utama to everyone: karena akan
menghasilkan protein yang penting untuk kehidupan

April 17, 2020 5:04 PM from harjono utama to everyone: potein yang baru
hasil translasi harus dimodif juga supaya : bisa kerja dengan benar dan di target
yang benar

April 17, 2020 5:04 PM from harjono utama to everyone: protein tersebut
juga aman selama perjalanannya menuju target (terhindari dari protease sitoplasma
sel).

April 17, 2020 5:05 PM from harjono utama to everyone: ini dikenal dengan
proses proses pascatranslasi protein
April 17, 2020 5:05 PM from harjono utama to everyone: sedangkan di
epigenetik diatas tadi : proses pascatranskripsi

April 17, 2020 5:06 PM from harjono utama to everyone: folding :

pelipatan molekul protein agar sesuai dengan konformasi molekul dan terutama
fungsinya yang benar

April 17, 2020 5:07 PM from harjono utama to everyone: polimerisasi :

tujuannya juga semodel, yaitu agar protein bisa bekerja dengan benar di target yang
benar

April 17, 2020 5:07 PM from harjono utama to everyone: penambahan

berbagai gugus kimiawi seperti fosfat, gula (glikosilasi) dan gugus lainnya agar
lebih menspesifikasi fungsinya

April 17, 2020 5:09 PM from harjono utama to everyone: proof reading :
pengecekan apakah proses susunan basa basanya sudah benar?. juga mudah rusak karena
spesies oksigen reaktif (ROS)

April 17, 2020 5:09 PM from harjono utama to everyone: karena DNA mt
tidak stabil maka dia mudah rusak dan berkontribusi luas dalam berbagai kelainan

April 17, 2020 5:10 PM from harjono utama to everyone: biologi molekuler
stress : lihat di gambar slide no 12 penyebab dan dampaknya.

April 17, 2020 5:11 PM from harjono utama to everyone: ROS : spesies
oksigen reaktif; RNS spesies nitrogen reaktif

April 17, 2020 5:12 PM from harjono utama to everyone: transcriptional

machinery : membantu proses transkripsi menjadi lebih cepat bahkan sangat cepat

April 17, 2020 5:13 PM from harjono utama to everyone: resikonya akan ada
error karena kecepatan itu, disinilah pentingnya proof reading (pengecekan ulang
hasil transkripsi)

April 17, 2020 5:14 PM from Ahmad Rohmadhon Holifatullah to everyone:

sedang memahami prof

April 17, 2020 5:14 PM from harjono utama to everyone: harus direnungkan
juga guys

April 17, 2020 5:14 PM from RyanHabibi to everyone: sedang mendalami

prof

April 17, 2020 5:15 PM from M. Nawawi Hasan Fatoni to everyone: iyaaa
mumet prof

April 17, 2020 5:15 PM from Ahmad Rohmadhon Holifatullah to everyone:

sedang merenung prof

April 17, 2020 5:15 PM from FEBRIANTI (1809511024) to everyone:

bingung prof, hehe

April 17, 2020 5:15 PM from harjono utama to everyone: semoga nanti malam
anda mendapat pencerhan dari ilmu ini baik melalui mimpi atau wisdom

April 17, 2020 5:15 PM from 1809511043_I GEDE GALYES PRANADINATA to

everyone: lebih berat dari memahami wanita prof
April 17, 2020 5:15 PM from Ketut Elok Sukardika 17017 A to everyone:
Hhhh

April 17, 2020 5:15 PM from kevin tri tama to everyone: setuju

April 17, 2020 5:15 PM from harjono utama to everyone: benar dan setuju
guys

April 17, 2020 5:15 PM from Ahmad Rohmadhon Holifatullah to everyone:

amin

April 17, 2020 5:16 PM from Gilang Andri Pratama 1809511023 to everyone:
di hayati prof

April 17, 2020 5:16 PM from gita kristyari 17-025 to everyone: baik
prof

April 17, 2020 5:16 PM from 1809511114 - Brainna Kirayna Ginting to

everyone: Baik, prof

April 17, 2020 5:16 PM from FEBRIANTI (1809511024) to everyone: baik

prof

April 17, 2020 5:16 PM from 1809511043_I GEDE GALYES PRANADINATA to

everyone: terimakasih prof\

April 17, 2020 5:16 PM from 1809511127_Wafiq Annisa to everyone: baik,

terima kasih, prof

April 17, 2020 5:16 PM from M. Nawawi Hasan Fatoni to everyone: baik
prof

April 17, 2020 5:16 PM from harjono utama to everyone: bye all

April 17, 2020 5:16 PM from gita kristyari 17-025 to everyone:

terimakasih prof

April 17, 2020 5:16 PM from Zelia Ximenes to everyone: Baik prof

April 17, 2020 5:16 PM from 1709511112 - Ni Putu Permata Dewi Maheswari
to everyone: terimakasih prof

April 17, 2020 5:16 PM from Annisafitri Lutviana to everyone: baik

prof terimakasih

April 17, 2020 5:16 PM from Denselina Lilis Patabang 17-017. Kelas A
(privately): terimakasih prof

April 17, 2020 5:16 PM from M. Nawawi Hasan Fatoni to everyone:

terimakasih 🙏