Beruflich Dokumente
Kultur Dokumente
This form is used in preparation of the program component. Entries on this form should be transferred to the University Board for
approval.Fields marked blue indicate NVU requested information and shall not be filled (if not meant otherwise), whereas yellow
fields are optional.
1. General Information
Pre-requisite Pre-requisite
Component(s): General Pathology qualifications: NA
(Component code(s)) (text description)
Post-requisite
Component replaces:
Component(s): NA NA
(if any)
(Component code(s))
Component is to be
Fall 2013 Date of proposal: 19.08.13
implemented:
Estimated student
150 Maximum class size: 15
numbers:
Applied for Available for Available to
Work experience/
minor N online N Exchange Y N
placement:
qualification: enrolment students:
Available to Prior
Non-degree N Registration Y Other N Other N
students: Requirement
2. Aims and Learning Outcomes
Component Description The systemic pathology course deals with pathology and pathophysiology of
(summary, especially important for elective
Components) disease in by organ systems, deals with demonstration of gross, and/or
microscopic features of the disease entities
The following teaching methodologies will be used:
• Didactic lectures: discussing a particular topic at length in an one hour
lecture.
• Paraclinical seminars: are conducted by a combined team of
pathologist and a clinician who discuss the pathophysiology and
clinical aspects of the particular disease entity.
• Case studies: The significant and common diseases are discussed in
the form of a representativeclinical case in which the clinical features,
the course of the disease in that particular patient and relevant
laboratory investigations are discussed by a clinical faculty in an
interactive manner. This is followed by demonstration of the gross and
microscopic features of the disease in that case by the pathologist.
This is followed by clinico-pathologic correlation.
Other or Detailed:
Please indicate which skills will be developed most as part of this Component. Please choose a minimum of 3
(Maximum of 5) from the list below.
Confidence Professionalism
Initiative
Practicals: 15 2 30 30
e-tutorials 15 2 30
Quiz -2 2 4
Class tests, exams and assessment:
MCQ -1 3 3
Independent learning: 113
(give details below)
Of 113 hrs allocated for independent learning 40 hrs are implied for preparing home assignments, 40 – for
library, 33 – preparing for exams.
Reading:
1) Robbins Basic Pathology: with STUDENT CONSULT Online
Access, 9e (Robbins Pathology)
Topic: Heart
Week 1
Content: Heart disease, overview of pathophysiology,
March16
Heart Failure: Etio-Pathogenesis, clinical manifestations. Compensatory
reactions - tachycardia, myocardial hypertrophy and Frank-Starling's
phenomenon.. Right heart failure, left heart failure, high-output failure,
Congenital heart disease, Left to right shunts (atrial septal defect, ventricular
septal defect, patent foramen ovale, Ductus arteriosus, atrioventricular epal
defects), right to left shunts (Tetralogyt of Fallot, transposition of great arteries,
truncus arteriosus, tricuspid atresia )
Reading:
WEEK 2 Rheumatic fever and Rheumatic Heart Disease : Pathogenesis, Morphology and
effects
MArch 21 Infective Endocarditis : Causes, Pathogenesis and Morphology
Pericarditis and other pericardial diseases,myocarditis, carcinoid heart disease
Cardiomyopathy
Reading:
Topic: Hematopathology
Week2
March 23 Content:
Constituents of blood and bone marrow, Regulation of hematopoiesis.
. Erythropoiesis, immature and mature forms of erythrocytes, signs of
immaturation. Anisocytosis, poikilocytosis and pathological forms of
erythrocytes. Disorders of Color index and Erythrocytes' sedimentation
rate. Circulating blood volume, alterations in circulating blood volume,
normo-, hypo- and hypervolemias, oligocytemic and policitemic states.
Erythrocytosis - definition, etio-pathogenessis and clinical manifestations.
Anaemia: classification and clinical features; clinical and lab. approach to
diagnosis
Reading:
Polycythemia,
Week3 BLEEDING RELATED TO
March 28 REDUCED PLATELET NUMBER:
THROMBOCYTOPENIA,
Chronic Immune Thrombocytopenic
Purpura (ITP), Drug-Induced Thrombocytopenia, Thrombotic
Microangiopathies:
Thrombotic
Thrombocytopenic Purpura (TTP) and
Hemolytic-Uremic Syndrome (HUS),
BLEEDING DISORDERS RELATED TO
DEFECTIVE PLATELET FUNCTIONS
HEMORRHAGIC DIATHESES RELATED TO
ABNORMALITIES IN CLOTTING FACTORS,
Von Willebrand Disease
Hemophilia,
DISSEMINATED INTRAVASCULAR
COAGULATION (DIC)
Lymphoid and myeloid Neoplasms
Reading:
Week 4
Topic: Urinary Tract Pathology.
April 4
Content: Glomerular disease, pathogenesis of glomerular disease,
clinical manifestations of renal disease, histologic alterations,
pathogenesis of glmerular disease, immune complex deposition,
circulating immune complex nephritis, antibodies to glomerular
cells,nephritic and nephritic syndromes
Focal segmental glomerulonephritis, poststreptococcal
glomerulonephritis, rapidly progressive glomerulonephritis, membranous
nephropathy, minimal change disease, HIV associated nephropathy,
Seondary MPGN, Alports disease, Chronic glomerulonephritis,Lupus
nephritis, diabetic nephropathy, amyloidosis, Goopasture syndrome,
wegeners granulomatosis.
Reading:
Reading:
Week 5
April11
Topic: Liver, Biliary Tract and Pancreas Pathology
Reading:
Quiz 1
Week 5 Content:
April 13
Penis, congenital anomalies, hypospadias and epispadas, phimosis, Inflammation,
Tumors, Condyloma Acuminatum, Carcinoma in situ, invasive Carcinoma
VAGINA
Development Anomalies
Premalignant and Malignant
Neoplasms
CERVIX
Infl ammations
Acute and Chronic Cervicitis
Endocervical Polyps
Premalignant and Malignant
Neoplasms
FALLOPIAN TUBES
Infl ammations
Tumors and Cysts
OVARIES
Non-Neoplastic and Functional Cysts
Ovarian Tumors
Reading:
Hypoparathyroidism, pseudohypoparathyroidism.
Reading:
Tumor and tumor like lesions, Ganglion and synovial cyst, tenosynvil giant cell
tumor
Soft tissue tumors and tumor like lesions, Fatty tumors. Lipoma, Liposarcoma.
Nodular fascitis. Myositis ossificans. Fibromatoses. Fibrosarcoma
Rhabdomyosarcoma. Leiomyomas. Leiomyosarcoma. Synovial sarcoma.
Osteonecrosis
Infections, Osteomyelitis, Skeletal syphilis
Reading:
Week 7
Topic: Central and Peripheral Nerves, Muscles
Central Nervous system
Content:
General reactions of the motor unit. Segmental demyelination. Axon degeneration and
muscle fiber atrophy. Nerve regenerationand reinervation of muscle. Reaction of the
muscle fiber.
May2 Content:
Reading:
Specify the type and timing of formal University examinations (exemptCoursework Assessment)
Duration When set Resit % of formal
Type of exam (hours) (usually 16-19 (usually 20-22 assessment
week) week) (not exceeding 40)
MCQ Exam 3 40
Rationale for assessment and relationship of assessment methods to learning outcomes (this information is not
published):
The component includes lectures and practicals. The latter ones comprise interactive workshops,
case-based discussions, using various histological and immunohistological images. Lectures highlight
important concepts and facts in each major topic.
5. Resources
Reading list:
Please indicate by checking the box specifying if a reading list is required for this Component. This information is to
be used by the library to manage resources:
1. Robbins Basic Pathology: with STUDENT CONSULT Online Access, 9e (Robbins Pathology), 2013
Vinay Kumar, Abul K. Abbas, Jon C. Aster
Comments:
(Use this box to make any additional notes. This information is not published).