Folk Chonthong Narkrit 1103

Organic Chemistry Project

Paroxetine is an organic compound that is composed of four functional groups Oxalic acid,

Malic acid, Fumaric acid and I-Tartaric acid. Paroxetine belongs to a group of medicine called

“Selective Reuptake Inhibitors” which is a class of drugs that are typically used as an

antidepressant in the treatment of the major depressive disorder, in which will balance the

chemical inside the brain. The patient shouldn’t be taking paroxetine if they are also using

pimozide or thioridazine which might lead to serious heart problems. The molecular weight of

Paroxetine is approximately 329.4 g/mol containing 1 H bond donor and also contains 5

Hydrogen bond acceptors. The exact mass of Paroxetine is 329.142722 g/mol. This organic

compound does not have any formal charges. Physical properties of this organic compound are

solid with a boiling point at - 451.7±45.0, melting point at -129-131°C and solubility is -5.4

mg/mL. Functional groups in Paroxetine could be applied to many things for example Fumaric

Acid could be applied to the process of making wheat and I-Tartaric also used for acidulant in

grapes and favoured beverages. Functional groups in this compound consists of

C19H20FNO3

(​3S,4R​)-3-(​1,3-benzodioxo​l-5-ylo​xy

methy​l)​-4-(4-fluorophenyl​)​piperidine

Favipiravir is an organic compound that consists of 3

biological compounds Guanosin, Inosine and AICAR and 2 Antivirals Ribavirin and

Favipiravir-ribose. It was discovered by a big chemical company in Japan, Favipiravir is a

modified pyrazine. Favipiravir is also known as T-705 and commonly applied to patients who

contain the RNA virus as antiviral medicine. The molecular weight of Favipiravir is approximately

at 157.1 g/mol, Monoisotopic mass is 157.028755 g/mol and exact mass is at 157.028755
Folk Chonthong Narkrit 1103

g/mol. Favipiravir contains 2 hydrogen bond donors, 4 hydrogen bond acceptors and 1 rotatable

bond. The melting point of Favipiravir is at - 187℃ to 193℃ and it is also slightly soluble in

water. The functional group in Favipiravir can be applied on to many things as well, for instance,

Guanosine is a protective role in response to

degenerative diseases or injury, Inosine could be used

to improve athletic performance and AICAR used in the

1980s to preserve blood flow to the heart during

surgery.

C5H4FN3O2

6-fluoro​-​3-oxo​-​3,4-dihydropyrazine​-​2-carboxamide

References

AICAR, AMPK's Activator: Basic Information and Popular Uses: AG Scientific Blog. (n.d.). Retrieved
from ​https://agscientific.com/blog/2014/01/aicar-ampks-activator-basic-information-and-popular-uses/

English, A. S. (2020, April 8). What is Favipiravir, the drug used in China to fight Covid-19? Retrieved
from https://en.as.com/en/2020/04/08/other_sports/1586359058_132520.html

Paroxetine. (n.d.). Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/Paroxetine

Tartaric Acid. (n.d.). Retrieved from

https://www.sciencedirect.com/topics/medicine-and-dentistry/tartaric-acid

Inosine: Uses, Side Effects, Interactions, Dosage, and Warning. (n.d.). Retrieved from
https://www.webmd.com/vitamins/ai/ingredientmono-704/inosine

Lanznaster, D., Dal-Cim, T., Piermartiri, T. C. B., & Tasca, C. I. (2016, October 1). Guanosine: a
Neuromodulator with Therapeutic Potential in Brain Disorders. Retrieved from
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036959/

Shiraki, K., & Daikoku, T. (2020, February 22). Favipiravir, an anti-influenza drug against life-threatening
RNA virus infections. Retrieved from
https://www.sciencedirect.com/science/article/pii/S0163725820300401

Paroxetine Uses, Dosage & Side Effects. (n.d.). Retrieved from ​https://www.drugs.com/paroxetine.html
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