1 ‫حزمة‬

A saturated very long chain fatty acid of 22 carbons is oxidized first in the peroxisome until it is 16
carbons in length and then it moves to the mitochondria for further oxidation. How many
?molecules of NADH are produced ‫هذا السؤال فيه إشكال‬

11

10

How much energy in ATP equivalents is generated upon the

complete oxidation of ?Palmitoyl CoA into CO2 and H2O

129

127

130

128

131

One of the following statements about fatty acid :synthase enzyme in HUMANS is NOT correct

Fatty acid synthase protein is the product of one single gene

NADPH is required for fatty acid synthase function

Fatty acid synthase enzyme is present in the cytosol

Fatty acid synthase is a complex of seven different enzymes encoded by seven different genes

Entry of glucose into one of the following tissues :requires the activity of insulin

Adipose tissues

Brain

Liver

Retina

Erythrocytes

When ketone body formation in the hepatocytes is active, one of the following events does NOT
:occur

Fructose 2,6 bisphosphate levels will be high

Malonyl CoA levels are low

PEPCK enzyme will be active

TCA cycle is inhibited

The ANSWERS

‫السؤال األول‬
.‫ وتم الغاؤه‬، ‫في عليه اشكاليه‬
‫السؤال الثاني‬
131

‫السؤال الثالث‬
adipose tissue

‫السؤال الرابع‬
Fatty acid synthase is a complex of seven different enzymes encoded by seven different genes

‫السؤال الخامس‬
Fructose 2,6 bisphosphate levels will be high

2‫حزمة‬

How many ATP molecules are produced upon the complete oxidation of palmitic acid into CO2 and
H2O:

127

131

130

129

125

One of the following will inhibit lipolysis:

Select one:

Starvation

Epinephrine

Cortisol

Glucagon

Insulin
When oleic acid is desaturated at carbon 6 and then elongated, what is the correct representation of
the product?

20:2(w-6)

19:2(7,9)

20:2(6,9)

20: 2(8,11)

One of the following is NOT a feature of a deficiency in cornitine transporter:

Select one:

Low levels of acyl cornitine in the blood

Low levels of free cornitine in the blood

CI Muscle pain upon excercise

High levels of ketone bodies

Hypoglycemia

One of tho following is note foaturo of patients with uncontrolled type 1 diabetos mellitus:

Elevated levels of free fatty acids

Active lipolysis

Active ketogenesis

Elevated levels of very low density lipoproteins (VLDL)

The ANSWERS

‫السؤال األول‬
129 ATP

‫السؤال الثاني‬
Insulin

‫السؤال الثالث‬
20:2(8,11)

‫السؤال الرابع‬
High levels of ketone bodies

‫السؤال الخامس‬
Elevated VLDL
3‫حزمة‬

One of the following will activate lipogenesis:

Select one:

Insulin

Starvation

Epinephrine

Glucagon

Cortisol

The hypoglycemia observed In patients with medium chain fatty acyl CoA dehydrogenase deficiency
is best explained by:

Decreased production of Acetyl CoA

Increased production of ATP

Increased conversion of Acetyl CoA to acetoacetate

Decreased ability to convert Acetyl CoA Into glucose

In terms of structure, one of the following is the only true keto acid:

Select one:

Linoleic acid

Acetoacetate

3-hydroxybutyrate Acetone

Acetyl CoA

When oleic acid is desaturated at carbon 6 and then elongated, what is a correct representation of
the product?

Select one:

An Ornega-10 fatty acid

19:2(7,9)

20: 2(8,11)

20: 2(w-6)
Individuals on a fat free diet for several weeks are most likely to develop a deficiency in:

PalmItic acid

Cholesterol

Oleic acid

Prostaglandins

Triglycerides

‫السؤال األول‬
Insulin

‫السؤال الثاني‬
Decrease production of acetyl coA

‫السؤال الثالث‬
Acetoacetate

‫السؤال الرابع‬

‫السؤال الخامس‬
Prostglandins