Beruflich Dokumente
Kultur Dokumente
LACTATE DEHYDROGENASE
by,
ISHAQUE P K
bIOCHEMISTRy
POndICHERRy UnIvERSITy
About…
• Isozymes also known as isoenzymes (or more generally
as Multiple forms of enzymes) are the physically distinct
forms of enzyme but catalyses the same chemical reaction.
• Enzymes that differ in structurally (amino acid sequence),
electrophoretically, immunologically and site of occurrence.
• Different isoenzymes are often organ-specific and their
determination may improve the specificity of enzyme tests.
• The heterogeneity of some isoenzymes is due to different
protein subunits which are coded for by separate genes.
Reasons For Isoenzyme……
Hexokinase:
• Hexokinase I/A.
• Hexokinase II/B.
• Hexokinase III/C .
• Hexokinase IV, also referred to as glucokinase.
Alkaline phosphatase (AP, ALP, SAP) :
• Liver-ALP (L-ALP).
• Corticosteroid-ALP (C-ALP, only in dogs).
• Bone-ALP (B-ALP).
• Intestinal-ALP (I-ALP).