VII.

DRUG STUDY

Mechanism of Indication Contraindication Adverse Nursing Health Teachings

Action Reactions Considerations
Generic Dosage: Inhibits Used for treating Hypersensitivity to -Rash - Instruct client to -Instruct client to avoid
Name: 10mg prostaglandin inflammation ketorolac, aspirin, -Ringing in the report any adverse alcohol and maintain
Ketorolac Frequency: synthesis by and pain in the other NSAIDs, or any ears reaction to the adequate hydration (2-3
Q4° for pain decreasing the operation site. component of the -Headaches physician or L/day of fluids) unless
Classifica Route: activity of the formulation; patients -Dizziness nurse. Tell patient instructed to restrict fluid
tion: Oral enzyme, who have developed -Drowsiness that adverse intake.
Nonsteroi cyclooxygenase, nasal polyps, -Abdominal reactions can
dal Anti- which results in angioedema, or pain occur with -Monitor for signs of pain
Inflammat decreased bronchospastic -Nausea overuse. relief, such as an
ory Drugs formation of reactions to other -Diarrhea - Do not drink increased appetite and
(NSAIDs) prostaglandin NSAIDs; active or -Constipation alcohol while activity
precursors, history of peptic ulcer -Heartburn taking ketorolac.
chemicals that disease; recent or -Fluid retention Alcohol can - Instruct client to avoid
cells of the history of GI bleeding increase the risk of taking ketorolac with
immune system or perforation; patients stomach bleeding aspirin or other NSAIDs
make that cause with advanced renal caused by such as ibuprofen
the redness, disease or risk of renal ketorolac. (Motrin, Advil), naproxen
fever, and pain of failure; labor and (Aleve, Naprosyn),
inflammation . delivery; nursing piroxicam (Feldene), etc.
mothers; prophylaxis
before major surgery
 VII. DRUG STUDY

Mechanism of Indication Contraindication Adverse Nursing Health

Action Reactions Considerations Teachings
Generic Dosage: Reduces fever by Used for the Contraindicated with -Chest pain - Give as necessary - Warn patient
Name: 500mg acting on the relief of fever, allergy to acetaminophen or -Dyspnea or when that acute
Paracetamol hypothalamus to headaches, and any component. -Rash temperature is overdoses (above
Frequency: cause vasodilatation other and pains -Fever more than 37.80C 1000 mg per
Classification: PRN & sweating. regarding Use cautiously with -Acute kidney - Instruct client to single dose and
Analgesic and surgical wound. impaired hepatic function, failure report any adverse above 4000 mg
Antipyretic Route: chronis alcoholism, and -Jaundice reaction like per day for
Oral pregnancy lactation. -Acute kidney allergies to the adults, above
failure physician or nurse. 2000 mg per day
-Hepatic - Do not exceed the if drinking
toxicity and recommended alcohol) of
failure dosage. Not to use paracetamol can
for marked fever cause potentially
(temperature fatal liver damage
higher than and, in rare
39.50C). Fever individuals, a
persisting longer normal dose can
than 3 days. do the same; the
risk is heightened
by alcohol .
 VII. DRUG STUDY

Mechanism of Indication Contraindication Adverse Nursing Health Teachings

Action Reactions Considerations
Generic Dosage: Inhibits bacterial Used for Urinary Hypersensitivity - Headaches -Determine history -Swallow tablets
Name: 500mg wall synthesis , tract infections, to cephalosporins - Diarrhea of hypersensitivity whole, do not chew
Cefuroxime Frequency: rendering cell otitis media and and related -Nause and reactions to or crush tablet.
TID wall osmotically other sever antibiotics; Vomiting cephalosporins,
Classificati Route: unstable, leading infections. pregnancy -Faitgue penicillins, and -Tablets may be
on: Oral to cell death by (category B), -Chills history of allergies, taken without regard
Anti- binding to cell lactation. -Confusion particularly to drugs, for food.
infective; wall membrane. - Anorexia before therapy is
antibiotic; -Paresthesia initiated. -Report lack of
Second - Seizures (High response, persistent
dose) -Monitor I&O rates diarrhea or S&S of
Generation
and pattern: anemia immediately.
Cephalospor
Especially important
in
in severely ill
patients receiving
high doses. Report
any significant
changes.
 VII. DRUG STUDY

Mechanism of Indication Contraindication Adverse Nursing Health Teachings

Action Reactions Considerations
Generic Dosage: Inhibits growth Used Contraindicated in -Nausea -Advice patient to -Take with food or
Name: 500mg of trichomonae forInflammatory patients hypersensitive -Pain avoid use of topical milk to reduce GI
Metronidazole and amoebae by papules and to drug or its -Cramps gel around eyes. upset.
Frequency: binding to DNA, pustules of acne ingredients, such as -Metallic or bad
Classification: TID resulting in loss rosacea parabens and other taste in mouth -Advise patient to -Do not perform
Topical drugs of helical nitroimidazole -Headache clean area thoroughly tasks that require
(local anti- Route: structure, stand derivatives -Bacterial before use and to wait mental alertness
infective) Oral breakage, infection 15 to 20 mins. After because dizziness
inhibition of Use cautiously in -flu-like cleaning skin before may occur.
nucleic acid patients will history or symptoms. applying drug to
synthesis, and evidence of blood minimize risk of local -Drug may turn
cell death. dyscrasia in those with irritation. urine brown; do not
several hepatic disease. be alarmed.