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Journal of Oral Rehabilitation 2005 32; 474–479

Comparative prospective study on splint therapy of anterior


disc displacement without reduction
M. STIESCH-SCHOLZ, J. KEMPERT, S. WOLTER, H. TSCHERNITSCHEK &
A . R O S S B A C H Department of Prosthetic Dentistry, Hannover University Medical School, Hannover, Germany

SUMMARY A prospective randomized study was car- opening increased by a mean of 8Æ05 mm in the
ried out to compare the therapeutic success of two group of patients treated with a stabilization splint
different types of splint in patients with painful (Group I). The comparable figure with pivot splint
anterior disc displacement of the temporomandib- therapy (Group II) was 8Æ26 mm. The VAS scale
ular joint. The patients in Group I (n = 20) received value in Group I was reduced by 30Æ54 units and in
stabilization splint therapy and the patients in Group II by 39Æ36 scale units. However, neither of
Group II (n = 20) pivot splint therapy. Clinical these differences between the groups was statisti-
investigation of the craniomandibular system was cally significant (Mann–Whitney U-test, P > 0Æ05). It
performed before and 1, 2 and 3 months after can be concluded that both types of splint provided
therapy and this was accompanied by subjective effective therapy in patients with anterior disc
evaluation by the patients of their symptoms, using displacement.
a validated questionnaire with visual analogue KEYWORDS: temporomandibular joint, craniomandib-
scales (VAS). There was a significant increase in ular disorders, disc displacement, occlusion, occlusal
maximum jaw opening and a significant reduction splint, therapy
in subjective pain in both groups during the course
of therapy (Wilcoxon test, P < 0Æ05). Active jaw Accepted for publication 8 August 2004

reposition splints. The latter have been described for the


Introduction
therapy of painful disc displacement with reduction.
Anterior disc displacement is an arthrogenic cranio- However, the indication is limited, induction of irre-
mandibular disorder, characterized by a change in the versible changes in the masticatory system is possible
position of the Discus articularis in relation to the and the prognosis of the condition is uncertain (5–7).
condyle. As the aetiology of disc displacements is The suggested functions of the stabilization splints are
multifactorial (1, 2) and there is frequent coincidence the stabilization of physiological static and dynamic
with myogenic and arthrogenic abnormalities in the occlusion, relaxation of the masticatory musculature
whole locomotor system (3, 4), an interdisciplinary and stabilization of the physiological stress relationships
treatment concept must be the goal (5). The dental in joint structures (8). There is evidence, that an
component of this therapy is usually occlusion splint occlusal stabilization splint is more effective in patients
therapy, aimed at a reduction in the leading symptoms, with craniomandibular disorders than a control non-
such as restricted mobility of the lower jaw and joint occluding appliance (9). In another study with random-
pain. Many different splint designs have been discussed assignment in patients with disk displacement without
in the literature (6). reduction, stabilization splint therapy showed signifi-
The splints may be classified into three major groups cant more pain reduction than therapy with transcu-
on the basis of their hypothesized function: the relax- taneous electric nerve stimulation (10). Other authors
ation/stabilization splints, the distraction splints and the found that the use of occlusal stabilization appliances in

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SPLINT THERAPY OF ANTERIOR DISC DISPLACEMENT 475

managing arthralgia is sufficiently supported by evi- Criteria for exclusion were prior surgery in the region
dence in the literature (11). of the TMJ, the presence of systemic underlying
The hypothesized function of the distraction splint is rheumatic disease, signs of psychosomatic illness, an
the reduction of the stress on the joint structures, by incomplete complement of teeth and a removable
causing caudal displacement of the condyle, accom- dental prosthesis.
panied by vertical widening of the joint space. This is The patients were assigned to one of the two
aimed at reducing pain and at protecting the involved treatment groups: Group 1 – Treatment with a stabili-
tissue. Pivot splint therapy, as described by Sears (12), is sation splint; Group II – Therapy with a pivot splint. A
a special form of distraction splint therapy. For this computer-generated sequence randomly assigned
purpose, a pivot is assembled in the region of the which of the two oral splints was to be worn by each
second molar, so that the mandible can rotate in the patient. The patients were distributed to this list in the
anterior cranial direction, resulting in caudal move- order of their first appearance.
ment of the condyle (6, 12). There are no reliable Group one consisted of 18 female and two male
published data from randomized comparative studies patients with an age range between 18 and 62 years
with these different types of splint. (mean 34Æ8  13Æ7), group two consisted of 17 female
The present prospective, randomized study includes and three male patients with an age range between 18
patients suffering from painful disc displacement of the and 64 years (mean 32Æ5  15Æ8). The mean duration
temporomandibular joint (TMJ) and compares the suc- of complaints before treatment was 15Æ3  13Æ8 weeks
cess of treatment with the two types of splint – the pivot in group one and 18Æ7  11Æ6 weeks in group two.
splint and the stabilization splint. The pivot splint was Fourteen patients in group one and 17 patients in group
used as the treatment and the stabilization splint as the two exhibited not only pain of the TMJ but also
active control. myofascial pain. None of the patients showed a history,
which referred to a psychosocial diagnosis like psycho-
logical impairment or low perceived live control (1).
Materials and methods

Patient Selection Therapeutic intervention

The study was approved by the Ethics Committee of The patients in Group I received a stabilization splint,
Hannover University Medical School. The study was which covered the whole upper dental arch. The splint
undertaken with the understanding and written con- was prepared in the articulator, in accordance with the
sent of each subject. recommendations of Ash (14). During the integration
Forty patients (35 female, five male) were enrolled in of the splint, care was taken that it was properly fitted.
this study who were suffering from symptoms in the The occlusal contacts during static occlusion and the
TMJ and who had visited the Department of Prosthetic canine guidance during dynamic occlusion were
Dentistry in Hannover University Medical School for checked intra-orally for balance.
this reason. The criteria for inclusion were the presence The patients in Group II were given a pivot splint, as
of anterior disc displacement without reduction and a described by Sears (12), with a bilateral pivot in the
normal complement of teeth. The definition of the region of the second molar. The fit was checked intra-
clinical diagnosis of anterior disc displacement was case orally and the ipsilateral contacts to the pivot were
history information of a sudden onset of limited mouth checked for balance. All splints were made by one
opening, restriction of condylar translation and TMJ person.
pain related to mouth opening or chewing (10, 13). For The patients in both treatment groups were instruc-
confirmation of the clinical diagnosis, magnetic reson- ted to wear the splints day and night excluding
ance imaging (MRI) examinations were carried out mealtimes for the whole period of the study
with the closed and open mouth positions in the (3 months). At each follow-up visit, it was checked
parasagittal section. For the MRI diagnosis the inter- that the contacts to the stabilization splint were
mediate zone criterion according to Orsini et al. (13) balanced and they were adjusted occlusally where
was used. For inclusion in the study all mentioned necessary. At the third follow-up visit (after 2 months),
clinical and MRI criteria had to be fulfilled. the pivot of the pivot splint was removed and the splint

ª 2005 Blackwell Publishing Ltd, Journal of Oral Rehabilitation 32; 474–479


476 M . S T I E S C H - S C H O L Z et al.

was adjusted to even occlusal contacts in a comfortable chewing) and during border movements (e.g. maximal
centric relation. There was no additional drug or active opening of the mouth).
manual therapy in either of the two groups. All examinations were carried out by one investi-
gator, who was blinded to the type of appliance each
subject was wearing. The patients were instructed not
Evaluation of the success of the therapy
to mention their group membership to this investigator,
Before (initial visit) and one (first follow-up), four to minimize bias. The investigation was monitored by
(second follow-up), eight (third follow-up) and an individual who was not enrolled in the trial.
12 weeks (fourth follow-up) after the beginning of
therapy, all patients underwent a clinical examination
Data analysis
according to the Craniomandibular Index of Fricton
and Schiffman (4). The examination included those Documentation and statistical data analysis were per-
items that reflect TMJ tenderness and functional prob- formed with the Windows data processing program
lems (limits in range of mandibular motion, deviation SPSS/PC (15). The non-parametric Wilcoxon test was
in movements, pain during movement, TMJ noise, TMJ used for paired values before and after treatment. The
tenderness) as well as those items that reflect the two groups were compared by using the non-paramet-
symptoms of muscle tenderness (extra-oral and intra- ric Wilcoxon–Mann–Whitney U-test for unpaired val-
oral muscular tenderness). Also a clinical examination ues. A P-value of < 0Æ05 was considered statistically
of the dental situation was performed in order to significant.
evaluate possible side effects of splint therapy such as
tooth intrusion, tooth loosening or sensitivity on biting.
Results
Therefore an occlusal foil was placed between the teeth
in order to investigate, if all teeth were in occlusal Maximal jaw opening was taken as the criterion for
contact with their antagonists. In addition a measure- lower jaw mobility and increased significantly in both
ment of the mobility score of the teeth was made and treatment groups (Table 1). At the fourth follow-up,
the patients were asked, if they had any sensitivity on the average maximal jaw opening in Group I (stabil-
biting. A change of the number of teeth with occlusal ization splint) was 40Æ93  7Æ49 mm and in Group II
contact with their antagonists, the number of teeth (pivot splint) 40Æ38  4Æ31 mm.
with sensitivity on biting or a change of the mobility During the total time of treatment, the mean max-
score between the follow-ups was assessed as a side imal protrusion increased in Group I from 4Æ94  1Æ95
effect. to 6Æ71  2Æ67 mm and in group II from 4Æ94  2Æ15 to
This was followed by subjective evaluation of pain of 6Æ85  2Æ08 mm. However, this difference in the
the craniomandibular system with visual analogue increase in mobility between the two groups was not
scales (VAS: 0 ¼ no pain, 100 ¼ extreme pain). In statistically significant (Wilcoxon–Mann–Whitney
each case, pain was measured at rest, during stress (e.g. U-test, P > 0Æ05).

Table 1. Maximal active jaw opening at the follow-up visits, with the two types of splint. The level of significance of the difference
between the splint groups (Wilcoxon–Mann–Whitney U-test) and of the values before and after treatment (initial visit and last follow-up,
Wilcoxon test) are presented

Stabilization Pivot Mean difference Level of


Visit splint splint (95% CI) significance

Initial visit 32Æ88  7Æ54 32Æ12  7Æ46 0Æ55 ()4Æ61–5Æ71) P ¼ 0Æ741


First follow-up 36Æ59  8Æ24 34Æ12  7Æ75 2Æ47 ()3Æ12–8Æ06) P ¼ 0Æ339
Second follow-up 35Æ53  7Æ30 35Æ28  7Æ54 0Æ25 ()4Æ86–5Æ36) P ¼ 0Æ961
Third follow-up 38Æ67  7Æ20 38Æ13  5Æ56 0Æ54 ()4Æ17–5Æ25) P ¼ 0Æ599
Fourth follow-up 40Æ93  7Æ49 40Æ38  4Æ31 0Æ55 ()4Æ31–5Æ39) P ¼ 0Æ685
Level of significance P ¼ 0Æ046 P ¼ 0Æ014

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SPLINT THERAPY OF ANTERIOR DISC DISPLACEMENT 477

Table 2. Pain intensity at follow-up visits: measured with the visual analogue scale. The level of significance of the difference between
the splint groups (Wilcoxon–Mann–Whitney U-test) and of the values before and after treatment (initial visit and last follow-up, Wilcoxon
test) are presented

Visit Stabilization splint Pivot splint Mean difference (95% CI) Level of significance

Initial visit 54Æ25  25Æ91 58Æ21  21Æ02 )3Æ96 ()20Æ09–12Æ17) P ¼ 0Æ523


First follow-up 44Æ56  26Æ78 46Æ67  25Æ58 )2Æ11 ()20Æ41–16Æ19) P ¼ 0Æ772
Second follow-up 35Æ25  29Æ19 35Æ32  24Æ84 )0Æ07 ()18Æ64–18Æ51) P ¼ 0Æ987
Third follow-up 28Æ93  28Æ51 31Æ41  29Æ16 )2Æ48 ()22Æ36–19Æ38) P ¼ 0Æ786
Fourth follow-up 23Æ71  26Æ54 18Æ85  22Æ54 4Æ87 ()14Æ61–24Æ34) P ¼ 0Æ430
Level of significance P ¼ 0Æ012 P ¼ 0Æ001

At the fourth follow-up, there was significant reduc- was assessed on the basis of the reduction in the leading
tion in subjective pain in both groups (Table 2). The symptoms. Maximal jaw opening and maximal protru-
reduction in pain in Group II (39Æ36  22Æ3 on the VAS sion were used as objective measures of restrictions in
scale) was greater than that in Group I (30Æ54  21Æ5), mobility. The patients’ subjective symptoms were eval-
although the differences were not significant (Wilcoxon– uated with validated VAS (16). The methods of eval-
Mann–Whitney U-test, P > 0Æ05). The corresponding uation correspond to those in the current literature
time courses indicate differences between the groups. (17–19).
There was a major improvement in the pain score even at This comparative study employed a stabilization
the second follow-up in Group II, although further splint and a special form of the distraction splint, as
improvement was only registered at the fourth follow- the use of both types of splint for the treatment of
up. The improvements in Group I were evenly distri- anterior disc displacement has been described in the
buted over the total time of treatment. international literature [6, 18, 20]. It had already been
The number of patients with tenderness to palpation shown in a previous study that the use of the pivot
in the muscles or in the TMJ and the number of splint gives the greatest reduction in symptoms as early
patients with deviations in mouth opening all decreased as in the first 8 weeks of treatment (20). For this reason
during therapy (Table 3). Here too there were no and to minimize the side-effects from this type of splint,
significant differences between the groups. the pivot splint was abraded after 8 weeks (third
Side-effects of splint therapy, such as tooth intrusion, follow-up), which then ensured balanced contacts.
tooth loosening or sensitivity on biting, were not found The efficacy of bite guard splints is thought to be due
in any of the patients. to several factors. First, all splints cause occlusal
decoupling and this can cause reorientation of estab-
lished neuromuscular reflex mechanisms, leading to
Discussion
the release of muscular tension and the recovery of
The present study compares the stabilization splint with physiological muscular coordination (21, 22). Secondly,
the pivot splint in the treatment of patients with disc it is discussed in the literature that the mechanical
displacement of the TMJ. The success of the treatment action of the splint reduces stress on the joint struc-
tures, for example, on the bilaminar zone which has
Table 3. Number of patients with signs of internal derangement been compressed by disc displacement. In particular,
before and after therapy
this effect has been described when distraction or pivot
splints are used (20). It is assumed in this context that
Stabilization splint Pivot splint
the occlusion contacts of the pivot splint near the joint
Initial Fourth Initial Fourth can activate the posterior temporal sections, causing
visit follow-up visit follow-up
rotation of the lower jaw, caudal displacement of the
Jaw muscle tenderness 14 5 17 4 condyles and distraction of the joints (12). It follows
Temporomandibular 9 4 8 2 that an increase in the mobility of the lower jaw may be
joint tenderness directly because of the reduction in stress on the joint,
Deviation in 14 6 10 7
or because of the reduction in pain resulting from the
mouth opening
decrease in stress.

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478 M . S T I E S C H - S C H O L Z et al.

Apart from these factors, successful treatment with of these results is qualified by the facts that the study
splints may be influenced by psychological effects, such population consisted of healthy volunteers without
as an increase in the cognitive consciousness for oral craniomandibular dysfunction and the splint was only
habits, a placebo or Hawthorne effect (6, 23) and worn for short periods. Moncayo et al. (25) carried out
spontaneous remission of the symptoms (18, 23). an X-ray study of the position of the condyle with a
The results of the present study tend to support the pivot splint in comparison with the position without
hypothesis that splints act neuromuscularly and psy- splint and found bilateral distraction of the condyle, at
chologically, as the success of the therapy in our group any rate, in 30% of the volunteers.
of patients was independent of the design of the Gray et al. (26) carried out a comparative study of
occlusal splint component in the two treatment groups treatment of patients with craniomandibular dysfunc-
and no significant difference was found between the tion with two different types of occlusion splint. Their
groups. Thus, the follow-ups found significant increases results support the idea that the occlusal splint design is
in maximal jaw opening and in maximal protrusion and only of minor importance. At the fourth follow-up,
there were no significant differences between the there was no significant difference between the treat-
groups in this respect. Pain was evaluated with VAS; ment success with a stabilization splint and with an
greater reductions were found in Group II (pivot interceptor, as described by Schulte (27). These results
splints), although the difference was not statistically support the neurological concept described by Türp
significant. Pain in Group II was only reduced in the et al. (28), according to which the therapeutic activity of
first and third months of treatment (first, second and occlusion splints is because of the specific reduction in
fourth follow-up), but remained about constant in the stress in painful muscle regions, caused by a change in
second month (third follow-up), suggesting that this the position in the lower jaw. This can then lead to the
splint acts by occlusal decoupling, followed by reorien- secondary effect of stress reduction in articular struc-
tation of neuromuscular reflex mechanisms. What tures.
makes this more plausible is that the occlusal situation The success rates in the present study are high in
of the patients in Group II was dramatically changed on comparison with published values. Thus Linde et al.
two occasions: first, at the start of the therapy, because (10) treated patients for 6 weeks with a stabilization
of the assembly of the pivot; secondly, after 2 months splint and found that only 60% of the patients reported
(third follow-up), because of reduction of the pivot. a reduction in the VAS pain scale of at least 50%.
Each of these changes then apparently led to a clear Okeson (29) found that 75% of patients were totally
reduction in pain. The occlusal situation of the stabil- free of pain two and a half years after treatment with a
ization splint was checked at each follow-up and reposition splint.
slightly abraded if necessary, resulting in slow and
even reduction in pain over the whole period of
Conclusion
treatment.
The sample size in the present study was 20 patients In summary, treatment with either of the two types of
per group. As the results showed very small outcome splint was acceptably successful and a significant
differences between the splint groups, it is very reduction in the leading symptoms could be achieved.
improbable that a larger sample size would lead to The results indicate that the success of the therapy was
clinically relevant and significant differences between less to do with the design of the occlusal splint
the groups. component and more to do with the basic decoupling
The results of Tsukasa et al. (24) also support the idea of established neuromuscular reflex mechanisms and
that the occlusal design has only a minor mechanical the consequent reduction in stress on the joints.
effect. These authors investigated the position of the
condyles when grinding the teeth in comparison with
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