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Chapter 1: ANS: 5. No. of spinal nerves arising from


each segment of spinal cord :

Physiology of ANS: a. 1
b. 2
c. 3
1. Nervous system is divided
d. 4
functionally into
a. Somatic and central
6. All of the following is controlled
b. Somatic and peripheral
by autonomic nervous system :
c. Somatic and Autonomic
a. Heart
d. Peripheral and Autonomic
b. Viscera
c. Moving hands
2. Choose one odd out word :
d. Glands
a. Brain stem
b. Cerebrum
7. Unit of function is :
c. Cerebellum
a. Reflex action
d. Spinal cord
b. Neuron
c. All of the above
3. No of segments of spinal cord :
d. Non of the above
a. 31
b. 32 True and false Questions:

c. 33
8. Ganglia aren't surrounded by any
d. 34
capsule
9. Autonomic ganglia are arised from
4. Which parts of spinal cord has
cranial and spinal origin
most number of segments :
10. Cranio spinal ganglia are larger
a. Cervical
than Autonomic ganglia
b. Thoracic
c. Lumber
11. Ganglion cells of Craniospinal
d. Sacral
ganglia are
e. Coccygeal
a. Unipolar
b. Pseudounipolar
c. Dipolar
 

d. Multipolar d. Thick Capsule surrounding it


all
12. Septa in the craniospinal ganglia 17. Pons Varolli is a part of :
are ____ to the capsule a. Cerebrum
a. Parallel b. Cerebellum
b. Perpendicular c. Brain stem
c. Scattered d. Non of the above
d. Non of the above
18. Which of them has motor function
13. Nerve fibres in Craniospinal ??
ganglia are : a. Autonomic ganglia
a. Unipolar b. Craniospinal ganglia
b. Myelinated
c. Non myelinated 19. Where does synapse lie?
d. Dipolar a. Bet ganglion and
postganglionic fibres
14. Shape of autonomic ganglia : b. Bet preganglionic fibres and
a. Oval ganglion
b. Spherical c. Bet ganglion cells
c. Rounded d. In craniospinal ganglia
d. Polyhedral
15. All of the following are present in 20. Craniospinal ganglia exists in :
the cranio spinal ganglia except a. All cranial nerves
a. Synapse b. Spinal nerves as dorsal ganglia
b. Nerve fibers c. Spinal nerves as ventral ganglia
c. Ganglion cells d. All of the above
d. Capsule
21. Stimulus is any ___ change in the
16. All of the following are present in environment
the autonomic ganglia except : a. Internal
a. Synapse b. External
b. Nerve fibers c. All of the above
c. Ganglion cells
 

d. Non of the above a. Anterior horn cell


b. Lateral horn cell
22. What happens after stretching of c. Medial horn cell
the urinary bladder ? d. Posterior horn cell
a. Contraction of bladder and 27. Receptor of autonomic reflex is
Relaxation of sphincter a. Skin
b. Contraction of bladder and b. Viscus of organ
sphincter c. All of the above
c. Relaxation of bladder and d. None of the above
contraction of sphincter
d. Relaxation of both 28. Efferent in somatic arc is __
neuron
23. All of the following are acting by a. 1
autonomic reflex except : b. 2
a. Viscera c. 3
b. Skeletal muscle d. 4
c. Cardiac muscle
d. Gland 29. All of the following are effector in
autonomic except:
st
24. 1 component of reflex arc is a. Gland
a. Effector b. Plain muscles
b. Efferent c. Skeletal muscles
c. Afferenet d. Cradiac muscle
d. Receptor
30. Synapse between axon and cell
25. All of the following are effector body is :
except : a. Axodendretic synapse
a. Gland b. Axosomatic synapse
b. Skeletal Muscle c. Axo-axonic synapse
c. Skin d. Dendrodendretic synapse
d. Smooth muscle
True or False

26. Center of somatic reflex is :


 

31. Inhibitory synapse is one in which 39. Order of spinal sacral segments
neurotransmitter hyperpolarize from which parasympathetic
postsynaptic membrane nerves originate:
32. Electrical synapse is most common a. 1st
33. Chemical synapse is specialized in b. 3rd
movement of ion from one cell to c. 5th
another d. None of the above
34. Presynaptic membrane is electron 40. In sympathetic nervous system ,
lucent preganglionic cells rely on ganglia
35. Synaptic cleft is about 20 mm near to
36. Postsynaptic membrane lies on a. Brain
target neuron b. Spinal cord
c. Effector
37. Ion responsible for mediating d. Receptor
function of chemical synapse
a. Calcium 41. Site of rely of parasympathetic
b. Phosphorous nerve fibres is :
c. Potassium a. Lateral ganglion
d. Sodium b. Collateral ganglion
c. Terminal ganglion
38. Sympathetic Nervous system d. All of the above
originate from :
a. Ventral root of Thoracic spinal 42. All of the following may be site of
segments rely for sympathetic preganglionic
b. Ventral root of lower lumber fibre except :
segments of spinal cord a. Lateral ganglion
c. Dorsal root of thoracic spinal b. Collateral ganglion
segments c. Terminal ganglion
d. Dorsal root of upper lumber d. Non of the above
spinal segments
43. Which of them in which
presynaptic nerves synapse with
more postsynaptic nerves
 

a. Sympathetic d. 10th cranial nerve


b. Parasympathetic
54. All the following are functions of
True or false: the facial nerve except:
44. Autonomic ganglia are site of rely a. Secretory and vasodilator to the
of preganglionic nerves coming lacrimal glands to cause shedding
from PNS of tears.
b. Secretory and vasodilator to the
45. Preganglionic fibres rely once
blood vessel of the nasopharyngeal
though it can pass through much
glands and soft palate.
ganglia c. Secretory and vasodilator to the
46. Sympathetic nervous system sublingual and submaxillary
originates from brain and sacral salivary glands to give copious
segments of the spinal cord watery saliva rich in electrolytes.
d. Vasodilatation of the blood vessels
47. Lateral sympathetic chain lie
in the anterior 1/3 of the tongue
between sympathetic chain and
organ
55. The postganglionic fibres of 9th
48. Ganglions are aggregation of
cranial nerve supply the parotid
nerve cell bodies outside CNS
gland and posterior 2/3 of the
49. Parasympathetic nerves originate
tongue
st
from 1 sacral spinal segment a. True
50. Parasympathetic and sympathetic b. False
are considered as somatic nervous
system 56. The preganglionic neurons of the
vagus nerve originate in the dorsal
51. Parasympathetic nervous system
motor nucleus of the vagus in the
forms craniosacral outflow
medulla oblongata.
52. Craniospinal ganglia are sites of a. True
rely of autonomic nerves b. False

53. Increasing power of lens is the 57. The postganglionic fibres of the
function of……. vagus nerve innervate all of the
following except:
a. 3th cranial nerve
a. Heart
b. 7th cranial nerve
b. Lungs
c. 9th cranial nerve c. Liver
 

d. Bladder 62. Sacral autonomic nerves provide


motor supply to all of the
58. All of the following are functions following except
of the vagus supplying the heart a. wall of the distal half of the colon
except b. wall of the rectum
a. Inhibition of all properties of the c. the internal anal sphincter
heart
b. Reduction of the 02 consumption 63. the wall of urinary bladder
of the cardiac muscle. ………… is called nervous
c. Vasodilatation of coronary erigens.
vessels a. Facial nerve
d. Inhibition of conductivity b. Vagus nerve
c. Sacral autonomic nerve
59. Bronchoconstriction is one of the d. Glossopharygeal
effects of the vagud nerve on the
lungs 64. Adrenergic autonomic fibers
a. True secrete ……… at their
b. False terminations
a. Acetylcholine
60. The vagus nerve provides motor
b. Norepinephrine
supply to all of the following
except: c. Both of them
a. Smooth muscles of stomach d. None of them
b. Smooth muscles of small
intestine 65. Adrenergic fibers include all the
c. the sphincters
synapses of all autonomic ganglia
d. proximal half of large intestine
a. True
smooth muscles
b. False

61. Proximal half of the colon


supplied by ……. While the distal 66. Cholinergic fibers supply
half supplied by …………. preganglionic fibres supplying the
a. Vagus , sacral autonomic adrenal medulla.
b. Sacral autonomic , vagus
a. True
c. Facial , vagus
b. False
d. Vagus , facial
 

67. Preganglionic nerve endings that 70. Acetylcholine is synthesized by


innervate sweat glands and blood …………. and hydrolysed into
vessels in the skeletal muscles are choline and acelic acid
cholinergic fibers by…………
a. True a. Choline acetyl transferase ,
b. False cholinesterase
b. Cholinesterase , choline acetyl
68. Nicotinic receptors are found in transferase
all of the following sites except:
a. The synapses between the pre- 71. Pseudocholinesterase destroys
and postganglionic neurons of acetylcholine in the cholinergic
both the sympathetic and nerve terminals
parasympathetic systems. a. True
b. In the membranes of skeletal b. False
muscle fibres at the
neuromuscular junction. 72. The transmitters in sympathetic
c. Supra-renal medulla. nervous system are
d. Sweat glands and blood vessels catecholamines, chiefly
of skeletal muscle innervated by norepinephrine and epinephrine
postganglionic cholinergic a. True
neurons of the sympathetic b. False
system.
73. The starting substance for
69. All of the following are nicotine- noradrenaline synthesis is……….
like action of acetylcholine except: a. Glycine
a. Stimulation of the autonomic b. Alanine
ganglia. c. Tyrosine
b. stimulation of all d. Lysine
postganglionic
parasympathetic endings 74. Adrenaline is synthesized by
c. Secretion of adrenaline and methylation of noradrenaline in
noradrenaline at adrenal the adrenal cortex
medulla. a. True
d. Contraction of skeletal muscles b. False
due to stimulation at the motor
end plates. 75. All of the following are true
concerning the fate of adrenaline
except:
 

a. Diffusion away from the nerve a. True


endings into the surroundings b. False
body fluids and thence into the 80. Noradrenaline has to a great
blood. extent more metabolic effect than
b. Reuptake into the adrenergic adrenaline.
nerve endings themselves by an a. True
passive transport process. b. False
c. Oxidation by monoamine
oxidase enzyme 81. Adrenaline has more inhibitory
d. Methylation by catechol-O- effects on the smooth muscles of
methyl tarnsferase the bronchioles and intestinal
wall. So it is more useful in the
76. Alpha adrenergic receptors treatment of bronchial asthma.
responding to noradrenaline and a. True
adrenaline, but they have higher b. False
affinity for adrenaline
a. True 82. The autonomic nervous system is
b. False
activated mainly by centres
located in ………..
77. Beta 1 receptors are present in the
smooth muscle of: bronchioles, a. the spinal cord
gastrointestinal tract, urinary b. brain stem
bladder while Beta2 receptors they c. Hypothalamus
are present chiefly in the heart d. All of the above
a. True
b. False 83. Spinal cord controls all of the
following except …….
78. Adrenaline has a greater effect on a. Micturition
cardiac stimulation than b. Defection
noradrenaline. c. Arterial blood pressure
a. True regulation
b. False d. Relaxation of the urinary
sphincter
79. Adrenaline causes only weak
constriction of the blood vessels, in 84. Brain stem controls all of the
comparison with the much following except………..
stronger constriction caused by a. arterial blood pressure
noradrenaline. b. heart rate
 

c. glandular secretion in the c. increasing motility of


gastrointestinal tract gastrointestinal tract
d. none of the above d. vasoconstriction and increased
arterial blood pressure
85. Medulla oblongata contains
centers of ………… 89. The limbic system plus the
a. centres for swallowing, coughing hypothalamus are concerned with
and vomiting emotions whether their genesis or
b. medullary centres for the their expression (mental and
autonomic reflex control of heart physical)
circulation a. True
c. centre of gastrointestinal b. False
peristalsis
d. all of the above 90. All of the following are severe
induced autonomic diseases
86. The pons contains centres for except……..
pupillary reflexes and a. peptic ulcer
accommodation for near vision. b. constipation or diarrhea
a. True c. heart palpitation
b. False d. Hypotension.

87. Stimulation of the posterior 91. What is number of courses that


hypothalamic nuclei result in preganglionic nerve has on
parasympathetic effects while entering the ganglionic chain :
stimulation of the anterior
a. 1
hypothalamic nuclei result in
b. 2
sympathetic effects
a. True c. 3
b. False d. 4

88. All of the following are 92. Coleic ganglia is considered :


sympathetic effects resulting from
a. Lateral ganglia
stimulation of posterior
b. Collateral ganglia
hypothalamus except:
c. Terminal ganglia
a. dilatation of pupils and palpebral
fissure d. Non of the above
b. increasing heart rate
 

93. Which of the following has its 100. Sympathetic nerves causes
sympathetic supply directly from secretions in lacrimal glands
splanchinic nerve ? 101. Increasing heart rate and
a. Adrenal cortex vasoconstriction of coronaries are
b. Adrenal medulla one of the functions of the
sympathetic NS
c. Renal Medulla
102. Bronchodilatation intense
d. Renal cortex
vasoconstriction of the pulmonary
blood vessels are mediated by
94. What is sympathetic action on eye sympathetic NS
pupil ? 103. Innervation of the adrenal
a. Dilatation medulla is preganglionic.

b. Constriction
104. All of the following are
c. Expansion
functions of sympathetic supply to
d. Conraction
the abdominal viscera except:
a. increasing the blood glucose
95. What is sympathetic action on level by conversion of liver
palepebral fissure ? glycogen into blood glucose
a. Narrowing b. Retention of bile.
c. Vasodilatation of the blood
b. Widening
vessels of the viscera
c. Retraction
d. secretion of adrenaline and
d. Protraction noradrenaline in the blood

True and False


105. all of the following are
96. Sympathetic nerves cause strong functions of sympathetic fibres to
vasoconstriction of cerebral vessels the pelvis except:
a. retention of faeces and urine
97. Sympathetic nerves cause
b. Vasoconstrictor to the blood
vasodilatation of vessels of salivary
vessels of pelvic viscera
gland c. Motor to the smooth muscle
98. Parasympathetic nerves causes of male sex organs
erection of the fair follicle d. Inhibitory to the smooth
99. Adrenal medulla is directly muscle of the proximal half
supplied by preganglionic nerve of the colon

fibres
 

106. All of the following are effects d. Improvement of blood supply


of sympathetic fibers to the limbs, to the muscles by
thoracic and abdominal parities vasodilatation
except: e. All of the above
a. Increase of muscle
glycogenolysis 109. The sympathetic discharge is
b. Vasoconstrictor to cutaneous increased in fasting animals and
blood vessels decreased when fasted animals are
c. Vasoconstriction to the blood reefed
vessels of the skeletal muscles a. True
d. Secretory to the sweat glands b. False

107. Orbelli Phenomenon is …….. True and false Qs concerning the


a. Better contraction, and early role of sympathetic nervous
fatigue of skeletal muscles system in emergencies:
b. delayed fatigue and early 110. Acceleration of the heart beat,
recovery of skeletal muscles decreases the force of myocardial
after fatigue contraction and raised blood
c. Better contraction and delayed pressure
fatigue of the skeletal muscles 111. Increasing glycogenolysis in
d. delayed fatigue and delayed the liver and elevation of blood
recovery of skeletal muscles glucose and free fatty acid level
after fatigue 112. Bronchoconstriction of
e. b and c bronchioles
113. Increased strength of muscle
contraction and early onset of
108. Orbelli Phenomenon occurs fatigue
due to: 114. Increased mental activity and
a. Activation of phosphorylase increased sweat secretion
enzyme needed for glycogen
breakdown and release of 115. When a small child's finger
energy in muscles. was stimulated or burned by a
b. Increase sensitivity of motor candle flame , he withdrew his
end-plate to acetylcholine.
hand so fast and began to cry,
c. Increase oxygen consumption
which of the following of event
and increased heat production.
likely to be true :
 

a. Spinal cord is responsible for the 118. Regarding what happens in the
all response of the child body during fasting state , Which
b. Spinal cord and Brain mediated of the following is True and False ?
this response a. When fasting occurs , at first
c. Medulla oblongata took part in blood pressure decrease , then
this response gradually it becomes stable at
d. This reflex action is considered to normal range
be autonomic reflex b. Decrease in level of fatty acids in
blood
116. Micturition has occurred to a c. Stimulation of glycogenesis in
young child , which of the liver
following centers is likely to have d. Stimulation of hypothalamus
mediated this action :
a. Brain 119. A worker is holding a large
b. Anterior horn cell of the spinal load in the factory , which of the
cord following can be observed in this
c. Lateral horn cell of the spinal worker :
cord a. Red face
d. None of the above b. Dry skin without sweat
c. Eye ball protruded
117. Sympathetic nerves whose d. None of the above
pregangilionic fibers originate
from all thoracic segments of the 120. If injury occurred to the
spinal cord mediate all of the autonomic nerve originated from
following except : the sacral segment , which of the
a. Inhibition to the smooth muscles following is likely to occur :
on wall of gall bladder a. Paralysis of wall of gall bladder
b. Stimulation of adrenal medulla b. Paralysis in the wall of the
c. Dilatation of eye pupil stomach
d. Inhibition to smooth muscle of c. Difficulty in the fecal discharge
the wall of urinary bladder d. Contraction of external urinary
sphincter
 

121. When you are having your d. Hard worker


lunch , all of the following can
occur except : 125. Chemical transmitter
a. Fast rate of heart beats mediating transmission on
b. Liability to urinate external sphincter muscle of the
c. Accommodation of near vision urinary bladder :
d. HCL secretion in stomach a. Acetylcholine
b. Nor adrenaline
122. A young child trying to joke c. Adrenaline
with a friend , he tries to frighten d. Muscarine
him , to his surprise ,, his friend
has died of fear , which of the 126. Which of the following
following is the main cause of substances can contribute to the
death : stimulation of sweat gland ?
a. Rupture of the respiratory a. Nicotine
pathway due to strong dilatation b. Adrenaline
b. Respiratory failure due to c. Nor adrenaline
collapse of bronchi d. Muscarine
c. Drop in blood pressure
d. Obstruction in GIT 127. All of the following are
different between Nor adrenaline
123. In case of sleeping which of and acetylcholine :
the following is most true : a. Synthesis steps
a. High level of glucose in the blood b. Site of initiation of synthesis
b. Contraction of eye pupil and c. Target
decrease power of lens d. Receptors
c. Fatty acids synthesis increases
d. Nor adrenaline level increases 128. Prolongation of the erection of
124. Miosis is likely observed in : the hair is due to alteration and
a. Angry man defect in :
b. Man returned from a tiring a. Alpha 1 adrenergic receptors
travel b. Alpha 2 adrenergic receptors
c. Student having exam c. Beta 1 adrenergic receptors
 

d. Beta 2 adrenergic receptors 132. Peptic ulcer is originated by


higher centers in nervous system
129. In the excitation of the heart due to :
,adrenaline is the more effective a. Rise in Sympathetic tones
excitant than Nor adrenaline due b. Rise in Parasympathetic tones
to : c. Abnormality in medulla
a. Greater ability of adrenaline to oblongata
excite Beta 1 receptors d. Defect in Limbic system
b. Lesser ability of Nor adrenaline
to excite Beta 2 receptors 133. Most common site for
c. Greater ability of adrenaline to enzymatic breaking of
excite Alpha 1 receptors Catcholamines is :
d. Lesser metabolic effects of a. Kidney
Adrenaline b. Liver
c. Spleen
130. Any destruction in the medulla d. Stomach
oblongata causes death mainly due
to: 134. Concerning hypothalamus put
a. Its ability to control GI peristalsis true or false :
b. Its effect on respiration a. Anterior part is stimulated
c. Its effect on regulation of the during stress
heart beat b. Posterior part causes
d. Both (a) and (b) hypertension
c. Anterior part causes erection of
131. Main centre of the nervous the hair
system controlling sympathetic d. It is considered the main vital
and parasympathetic tones is : center
a. Cerebral cortex indirectly
b. Hypothalamus
c. Mid brain
d. Cerebral cortex directly
 

Answers:
1. C 37. A
2. D 38. A
3. A 39. B
4. B 40. B
5. B 41. C
6. C 42. C
7. A 43. A
8. F 44. F
9. F 45. T
10. T 46. F
11. B 47. F
12. A 48. T
13. B 49. F
14. C 50. F
15. A 51. T
16. D 52. F
17. C 53. A
18. A 54. D
19. B 55. B
20. B 56. A
21. C 57. D
22. A 58. C
23. B 59. A
24. D 60. C
25. C 61. A
26. A 62. C
27. B 63. C
28. A 64. B
29. C 65. B
30. B 66. A
31. T 67. A
32. F 68. D
33. F 69. B
34. F 70. A
35. F 71. B
36. T 72. A
 

73. C 111. T
74. B 112. F
75. B 113. F
76. B 114. T
77. B 115. B
78. A 116. C
79. A 117. D
80. B
118.
81. A
a. T
82. D
83. C b. F
84. D c. F
85. D d. T
86. B 119. C
87. B
120. C
88. C
121. A
89. A
122. A
90. D
91. C 123. C
92. B 124. B
93. B 125. A
94. A 126. D
95. B
127. B
96. F
128. B
97. F
98. F 129. A
99. T 130. D
100. F 131. A
101. F 132. B
102. F 133. B
103. T
134.
104. C
a. F
105. D
106. C b. T
107. E c. T
108. E d. F
109. B
110. F
 

Pharmacology of ANS : 6. Atropine is :-


a. muscarinic receptor blocker
1. The mechanism of transduction in b. nicotinic receptor blocker
nicotinic receptors is:- c. reversible anticholinesterase
a. G – protein coupled d. none of the above
b. Inhibition of cAMP
c. Na+ influx 7. Hydrolysis of acetylcholine in the
d. K+ influx plasma is carried by :-
a. true cholinesterase
2. M3 receptors found in:- b. pseudocholinesterase
a. exocrine glands c. atropine
b. smooth muscle d. MAO
c. vascular endothelium
d. all of the above 8. Carbachol is used for the
treatment of :-
3. All of the following are direct M – a. postoperative retention of
stimulant except :- urine
a. carbachol b. paralytic ileus
b. bethanecol c. glaucoma
c. pilocarpine d. peptic ulcer
d. neostigmine
9. All of the following are
4. The irreversible anticholinesterase contraindications to choline esters
is : except :-
a. organophosphorus a. hyperthyroidism
b. physostigmine b. coronary insufficiency
c. neostigmine substitutes c. bronchial asthma
d. neostigmine d. pregnancy

5. The effect of acetylcholine on the 10. Pilocarpine is used systemically


eye : for :-
a. myosis a. atropine overdose
b. ciliary muscle contraction b. glucoma
c. stimulation of dilator pupillae c. myasthenia gravis
muscle d. Alzheimer
d. a and b
11. the drug used for treating
Alzheimer is : -
 

a. neostigmine b. Nicotine
b. carbachol c. Acetylcholine
c. physostigmine d. Scopolamine
d. edrophonium

17. I.V. injection of atropine at first


12. all of the following is true about
produces
neostigmine except : -
a. Tachycardia
a. used in diagnosis of
b. Bradycardia
myasthenia gravis
c. Both of them
b. antidote to curare
c. used in glaucoma d. Non of the above
d. paralytic ileus
18. Because most vascular beds lack
13. The drug used in treatment of parasympathetic innervation.
chronic myasthenia gravis is :- atropine has no action on
a. neostigmine a. Blood vessels
b. physiostigmine b. Blood pressure
c. atropine c. Both of them
d. pyridostigmine
d. Non of the above

14. all of the following used in the


19. ......... doses of atropine in children
treatment of irreversible
produce cutaneous vasodilatation
anticholenesterases poisoning
and flushing of the blush area
except
a. Therapeutic
a. atropine
b. neostigmine b. Toxic
c. oximes c. Small
d. anticonvulsant d. Non of the above

15. Atropine is absorbed from all sites 20. Atropine cause .......... of gastric
of administration. secretion
a. True a. Increasing
b. False b. Decreasing
c. No effect
16. Atropine blocks the muscarinic d. Non of the above
receptors by competing with
a. Muscarin
 

21. Atropine has an effect on urinary c. 7-10 days


bladder as it cause d. 8-10 days
a. Relax wall of bladder
b. Contraction of sphincter 26. Local application of atropine in
c. Both of them the eye, or its systemic
d. Relax of sphincter administration produces:
a. Loss of the light reflex.
22. Atropine cause reduction of b. Inhibition of lachrymation.
salivary, lachrymal, gastric, c. Cycloplegia
bronchial and sweat secretion. d. All of the above
a. True
b. False 27. When atropine is given
systemically, it takes
23. paralysis of the constrictor a. Few seconds
pupillae muscle is one of the b. Few minutes
effects of atropine on the eye and c. Few hours
it is called d. Few days
a. miosis
b. passive mydriasis 28. An atropine injection is given half
c. active mydriasis an hour before general
d. all of the above anaesthesia in order to:
a. Decrease salivary and
24. cycloplegia is Paralysis of the bronchial secretions
............ leading to loss of b. Protect against the inhibitory
accommodation to near objects. effect of morphine
a. ciliary muscle c. Protect the heart from
b. constrictor pupillae muscle excessive vagal tone
c. both of them d. All of the above
d. non of the above
29. All of the following are from side
25. The duration of action of atropine effects of atropine except
following its local application to a. Dryness of mouth, blurred
the eye is vision and tachycardia.
a. 7-11 days b. Depression of CNS.
b. 6-10 days c. Acute glaucoma
 

d. elevation of body temperature b. Buscopan


in children c. Pirenzepine
d. Eucatropine
30. we shouldn't use atropine in all
these condition except 35. .............. has no antisecretory
a. Fever action(not for peptic ulcer).
b. Cardiac patients. a. Hyoscine butyl bromide
c. Thyrotoxicosis b. Pirenzepine
d. Antispasmodic c. Oxyphenonium
d. Cyclopentolate
31. All of These compounds have the
advantage of shorter duration of 36. ................ cross to CNS with less
action than atropine except peripheral side effects
a. Cyclopentolate a. Eucatropine
b. Tropicamide b. Benztropine
c. Pirenzepine c. Oxyphenonium
d. Eucatropine d. Cyclopentolate

32. Hyoscine is preferred to atropine 37. ............. used to relax bladder and
in preanaesthetic medication increase its capacity in cases of
a. True urinary incontinence.
b. False a. Emepronium
b. Buscopan
33. ........... is used for For peptic ulcer c. Pirenzepine
(anti-secretory) and colics d. Eucatropine
(antispasmodic).
a. Cyclopentolate 38. Unlike atropine, ........ doesn.t
b. Tropicamide increase viscosity of bronchial
c. Oxyphenonium secretion.
d. Buscopan a. Emepronium
b. Buscopan
34. ............. Doesn.t affect the eye and c. Pirenzepine
its accommodation, therefore, may d. Ipratropium
be used in glaucoma.
a. Oxyphenonium
 

39. Pirenzepine doesn't not slow 44. Trimetaphan main use is to


gastric emptying so doesn' t produce controlled hypertension
prolong exposure of ulcer bed to in anaesthesia during plastic and
acid neurosurgery
a. True a. True
b. False b. False

40. ......... is a very short acting 45. All of the following are effects of
competitive ganglion blocker and histamine release except:
is a histamine liberator. a. Bronchospasm
a. Emepronium b. Hypertension
b. Buscopan c. Excessive bronchial and gastric
c. Trimetaphan
secretion.
d. Eucatropine
d. None of the above

41. Trimetaphan is administered by


46. All of the following give
I.V. drip infusion of ...... solution
synergistic effect with competitive
a. 1:100
blockers except:
b. 1:1000
c. 1:10000 a. Aminoglycosides

d. Non of the above b. Chlorpromazine


c. Neostigmine
42. Inhaled ipratropium has a d. quinidine
selective bronchodilator action.
a. True 47. ……….. agument paralysis
b. False a. inhalational anaesthetics
b. quinidine
43. The vasodilator effect of c. Chlorpromazine
trimetaphan is mostly due to: d. All of the above
a. ganglionic blocking effect.
b. A histamine releaser. 48. An overdose of curare produces:
c. A direct vasodilator effect. a. Failure of respiration due to
d. All of the above paralysis of respiratory muscles.
b. Hypotension.
c. Histamine release leading to
bronchospasm …..
 

d. All of the above c. ATRACURIUM


d. VECURONIUM
49. Precautions should be considered
in treatment of curare alkaloids 53. Which drug of these is the most
toxicity with antidotes include: potent:
a. atropine must be given few a. GALLAMINE
minutes before neostigmine b. PANCURONIUM
b. avoid overdosage of c. ATRACURIUM
neostigmine d. VECURONIUM
c. both of them
d. none of them 54. Which of the following has no
histamine releasing action:
50. all of the following are true about a. GALLAMINE
gallamine except: b. PANCURONIUM
c. ATRACURIUM
a. It has about 1/5 the activity of d. VECURONIUM
d-tubocurarine as a
neuromuscular blocker. 55. ............. a hormone secreted from
adrenal medulla that releases
b. It has a longer duration of
substrates for metabolism, and in
action
emergencies promotes blood flow
c. It has a much weaker to skeletal muscles.
ganglionic blocking activity. a. Noradrenaline
b. Adrenaline
d. It has a much weaker histamine
c. Dopamine
releasing action.
d. Non of the above
51. Which of the following has the
longer duration of action: 56. The main functions of ............. are
a. GALLAMINE maintenance of normal
b. PANCURONIUM sympathetic tone & adjustment of
c. ATRACURIUM circulatory dynamics.
d. TUBOCURANINE a. Noradrenaline
b. Adrenaline
52. Which of the following is c. Dopamine
metabolized by the liver: d. non of the above
a. GALLAMINE
b. PANCURONIUM
 

57. When we use an intermediate dose b. Beta1 . receptors


of dopamine as a drug it will c. Alpha 2 receptors
activate d. Beta 2 receptors
a. Alpha . receptors
b. Beta . receptors 62. All the subtypes of alpha-
c. D1 receptors adrenoceptors act by stimulation
d. D2 receptors of adenylate cyclase.
a. True
58. Adrenergic innervated organs and b. False
tissues tend to have only one
subtype of adrenergic receptors 63. ........ is a Presynaptic adrenergic
a. True receptor that inhibits release of
b. False Noradrenaline from the nerve
terminals
59. Stimulation of............ by a. Alpha 1
catecholamines activates b. Alpha 2
phospholipase C c. Beta 1
a. Alpha 1. receptors d. Beta 2
b. Beta1 . receptors
c. Alpha 2 receptors 64. Modulation of neurotransmission
d. Beta 2 receptors in central & sympathetic nervous
system is the action of ....... receptor
60. Increasing of cytoplasmic calcium a. Beta 1
may be due to release of ............ b. Beta 2
after stimulation of alpha 1 c. D1
receptor d. D2
a. Diacylglycerol
b. inositol triphosphate 65. Beta 2 receptor stimulate
c. adrenalin micturition
d. noradrenalin a. True
b. False
61. stimulation of ............ causes
feedback inhibition of the ongoing 66. Using large dose of dopamine as a
release of noradrenaline from the drug activate ............ receptors
stimulated adrenergic neuron. a. Alpha
a. Alpha 1. receptors b. Beta
 

c. D1 a. Mode of action
d. D2 b. Chemical structure
c. Spectrum
67. Beta 2 receptor increase glucose d. Non of the above
level in the blood
a. True 72. Catecholamines are compounds
b. False that contain a catechol nucleus
and may be natural as
68. All of the following are from the a. Adrenaline
direct acting b. Noradrenaline
SYMPATHOMIMETICS except c. Dopamine
a. Noradrenaline d. All of the above
b. Isoprenaline
c. Amphetamine 73. When endogenous catecholamines
d. Phenylephrine given parenterally, they enter the
CNS in significant amounts.
69. .............. increase the concentration a. True
of catcholamines in the synapses.to b. False
inhibt the reuptake of
noradrenalin into the nerve 74. ............... is a synthetic
ending catecholamine, is similar to
a. Cocaine endogenous transmitters but not
b. Isoprenaline readily taken up into nerve
c. Amphetamine endings.
d. Phenylephrine a. Noradrenaline
b. Dopamine
70. All of the following are dual c. Isoprenaline
SYMPATHOMIMETICS except d. Adrenaline
a. Dopamine
b. Pseudoepherine 75. Non-catecholamines do not resist
c. Ephedrine MAO and COMT enzymes and so
d. Amphetamine they are active orally
a. True
71. According to ............ we can b. False
classify SYMPATHOMIMETICS
into selective and non- selective
 

76. Inactivation of adrenaline and b. False


noradrenaline occurs by
a. Neuronal Uptake 82. Adrenaline acting on beta 1-
b. Extraneuronal uptake adrenoceptors exerts positive
c. Enzyme Destruction a. chronotropic effect
d. All of the following b. inotropic effect
c. dromotropic effect
77. The normal level of VMP in urine d. all of the above
is ........ mg /24 hours urine
a. 2.5 . 5 83. Adrenaline causes elevation of
b. 2 - 6.5 ............blood pressure due to
c. 3.5 . 6 increased cardiac output
d. 5.5 . 6 a. Systolic
b. Diastolic
78. Pheochromocytoma is a tumor of c. Both of them
adrenal medulla secreting d. Non of the above
noradrenaline and adrenaline.
a. True 84. When we use higher dose of
b. False adrenalinet4 it will .......... diastolic
blood pressure
79. Both enzymes (MAO &COMT) are a. Increase
present in all of the following b. Decrease
except c. Have no effect
a. Liver d. Non of the above
b. Kidney
c. Spleen 85. Adrenaline always used during
d. Intestinal mucosa delivery to cause contraction of
the uterus
80. Oral administration of adrenaline a. True
is effective b. False
a. True
b. False 86. Adrenaline can be used for
treatment of glaucoma
81. We can use adrenaline by all a. True
routes of administration b. False
a. True
 

87. Adrenaline increases blood a. Beta 2-agonists


glucose level by all of the b. Ephidrin
following except c. Dipivefrin
a. Inhibition of insulin secretion d. All of the above
b. decreasing release of glucagon
c. Increase in hepatic 93. All of the following are adverse
glycogenolysis effects of adrenaline except
d. transient increase in blood K+ a. Cardiac arrhythmia
followed by a prolonged fall b. Anxiety and restlessness.
c. Hypotension
88. adrenaline delays fatigability by d. Headache, weakness and
increasing blood flow. tremors.
a. True
b. False 94. Extravasation of parenterally
administered adrenaline causes
89. Adrenaline is the physiological severe vasoconstriction , resulting
antagonist of histamine. in
a. True a. tissue necrosis
b. False b. gangrene
c. both of them
90. Adrenaline is not given with local d. non of the above
anesthetics subcutaneously
because it increases bleeding from 95. noradrenaline cause increase of
the site of operation. ........... blood pressure
a. True a. systolic
b. False b. diastolic
c. both of them
91. Adrenaline is given in cases of d. non of the above
cardiac arrest
a. True 96. Noradrenaline has limited
b. False therapeutic value, it can use for
a. acute hypotensive
92. ........ is a prodrug that is b. septic shock
hydrolyzed to adrenaline, are used
c. both of them
topically in treatment of open-
d. non of the above
angle glaucoma.
 

97. using ...... infusion rates of 102. The moderate infusion rates of
dopamine, it dilates renal and dopamine (5-10
mesenteric blood vessels micrograms/kg/minute ) is called
a. low a. Renal dose
b. moderate b. Cardiac dose
c. high c. vasopressor dose
d. all of the above d. all of the above

98. At moderate infusion rates of 103. vasopressor dose of dopamine


dopamine , it stimulates ....... cause
receptors a. vasodilatation
a. Alpha 1 b. vasoconstriction
b. Beta 1 c. both of them
c. Alpha 2 d. non of the above
d. Beta 2
104. dopamine is preferred to take
99. Dopamine drug is less liable to orally because it highly absorbed
cause tachycardia and arrhythmia a. true
than other catecholamines. b. false
a. True
b. False 105. Isoprenaline stimulates beta
receptors by :
100. Dopamine is used in treatment a. Acting directly on them
of all of the following except
b. Increasing release of
a. Acute heart failure.
noradrenaline
b. open-angle glaucoma.
c. Inhibiting reuptake of
c. Hypovolaemic shock
noradrenaline by nerve
d. septic shock.
endings
d. All of the above
101. Dopamine .......... cardiac output
and renal blood flow e. B & C

a. Increase
b. Decrease 106. The duration of action of
c. Has no effect isoprenaline is longer than
d. Non of the above
 

adrenaline and noradrenaline 110. The major advantage of


because : Dobutamine over than other
a. It cannot be given orally sympathomimetics is that :
b. It’s not reuptaken by nerve a. It increases the cardiac output
endings and stroke volume
c. It’s stable and not metabolized b. It has a little effect on the heart
d. It stimulates releasing of rate
noradrenaline c. It doesn’t significatly elevate
myocardium oxygen demands
107. Isoprenaline is a synthetic d. All of the above
catecholamine which can be
given orally or parentrally : 111. Dobutamine is given by :
a. True a. Intravenous infusion
b. False b. Intravenous injection
c. Oral adminstration
108. All of the following can be one d. Sublingual administration
of the pharmacological actions of
isoprenaline EXCEPT : 112. Although Phenylephrine is an
a. Tachycardia alfa 1 selective agonist , it has no
b. Increase in the force of heart direct stimulant effect on the heart
contraction because :
c. Mydriasis a. Phenylephrine directly causes
d. Bronchodilatation vasodilatation which indirectly
produce reflex bradycardia
109. All of the following are correct b. Phenylephrine directly causes
about Dobutamine EXCEPT : vasodilatation which indirectly
a. It’s a synthetic catecholamine produce reflex tachycardia
b. It acts on dopamine receptors c. Phenylephrine directly causes
c. It stimulates mainly beta 1 vasoconstriction which
receptors indirectly produce reflex
d. it acts directly on adrenergic tachycardia
receptors d. Phenylephrine directly causes
vasoconstriction which
 

indirectly produce reflex c. Inhibiton of central


bradycardia sympathatic outflow
d. Non of the above
113. Unlike directly acting e. A & C
catcholamines Phenylephrine :
a. Can be given orally 116. in order to reduce the IOP in
b. Has prologed duration of chronic open-angle glaucoma we
action use :
c. Can cause mydriasis without a. Brimonidine
cycloplegia b. Clonidine
d. All of the above c. Phenylephrine
e. A & B d. Apraclonidine
e. A & D
114. All of the following can be one
of the therapeutic uses of 117. All of the following are
Phenylephrine EXCEPT : Sympathomimetics which are used
a. As a topical ocular preparation as nasal decomgestants EXCEPT :
because it doesn’t cause a. Phenylephrine
cycloplegia b. Brimonidine
b. As nasal decongestant in c. Ephedrine
allergic and viral rhinitis d. Pseudoephedrine
c. Hypotention caused by spinal
anaesthesia 118. Sympathomimetics are used as
d. As a mydriatic for fundus nasal decomgestants because they :
examination a. Produce vasoconstriction of
mucosal BVs
115. Clonidine and alfa- b. Reduces oedema of the nasal
methylnoradrenaline decrease mucosa
blood pressure by : c. Improve ventilation and nasal
a. inhibition of noradrenaline stuffuness
release d. Cause relief of allergic rhinitis,
b. Bradycardia sinusitis and common cold
 

e. All of the above c. They decrease the brochial


secretions
119. Rebound congestion is an d. All of the above
adverse effect of
Sympathomimetics are used as 122. All of the following are true
nasal decomgestants caused by : about Salbutamol EXCEPT :
a. Secondery vasodilatation a. It Has a little effect on the
b. Subsequent temporary heart
increase in nasal congestion b. Its effect lasts about 4 hours
c. Atrophy of the cilia of the c. It’s stable and not metbolized
nasal mucosa d. It cannot be given orally
d. A & B
e. A & C 123. Salmetrol and Formoterol are :
a. Long –acting beta2 agonists
120. All of the following are adverse b. Can be given by inhalation
effects of Sympathomimetics are c. Used for the relief of acute
used as nasal decomgestants asthma attack
EXCEPT : d. All of the following
a. Stinging , burning and drying e. A & B
of the nostrils
124. Salbutamol and Terbutaline are
b. Vasoconstriction of mucosal
the same in all of the following
blood vessels
EXCEPT :
c. Atrophy of the cilia of the
nasal mucosa a. Duration of action
d. Restlessness and anxiety b. Way of adminstration
c. Selectivty to beta2 adreginc
121. Unlike non-selective beta receptors
adregenic agonists beta 2 selective d. Theraputic uses
adrenergic agonists can be used in
the Treatment of bronchial asthma
125. All beta 2 selective
because :
adrenergic agonists are given
a. They don’t stimulate the heart
b. They cause bronchodilatation
 

orally , parentrally or by c. Inhibiting reuptake of


inhalation : noradrenaline by nerve
endings
a. True
d. All of the above
b. False
e. B & C
126. Ritodrine and Terbutaline have a
130. Tachyphylaxis is common with
common theraputic use which is :
amphetamine due to noradrenaline
a. Postponing premature labour depletion :
b. Treatment of bronchial asthma
a. True
c. Treatment of obstructive lung
b. False
diseases
d. B & C 131. Amphetamine produces weight
loss by :
127. Serious hyperkalaemia may
result from beta2 agonist therapy : a. Depressant action on appetite
b. Increasing energy expenditure
a. True
c. Decreasing absorbtion of food
b. False
d. A & B
128. All of the following are adverse e. A & C
effects of beta2 agonists EXCEPT :
132. Amphetamine is used for
a. Skeletal muscle tremor ( sympathomimetic and CNS effects :
particularly in hands )
a. True
b. Bradycardia and palpitation
b. False
c. Headache and nervousness
d. Peripheral vasodilatation 133. Amphetamine can be used for
treatment of :
129. Sympathomimetics actions of
Amphetamine on alfa and beta a. Nacrolepsy
receptors are caused by : b. Attention deficit syndrome
c. Depression
a. Direct stimulation
d. All of the above
b. Increasing release of
e. A & B
noradrenaline
 

134. All of the following are side d. They cause hypertention


effects of Amphetamine EXCEPT :

a. Insomania, anxiety, restless 137. Amphetamine and Ephedrine


and hyperactive reflexes share the following adverse effects
b. Tolerance and addiction Except :
c. Weight loss
a. Tachyphylaxis
d. Hypertention, palpitation and
b. Insomnia
anginal pain
c. Cardiac stimulation
e. Cardiac arrhythmia
d. Anxiety
e. Urine retention in old patients
135. Sympathomimetics actions of with enlarged prostate
Cocaine on alfa and beta receptors are
caused by :
138. Mechanism of action of
a. Direct stimulation Ephedrine is :
b. Increasing release of
a. Direct stimulation of alfa and
noradrenaline
beta receptors
c. Inhibiting reuptake of
b. Increasing release of
noradrenaline at both
noradrenaline
peripheral and central neurons
c. Inhibiting reuptake of
d. All of the above
noradrenaline by nerve
e. B & C
endings
d. A & B
136. Amphetamine and Cocaine are
139. Ephedrine has a good oral
similar in all of the following except :
absorption and it enters the CNS :
a. They have the same indirect
a. True
Sympathomimetic mechanism
b. False
of action
b. They cause vasoconstriction 140. Ephedrine and Pseudoephedrine
and cardiac stimulation are used for :
c. They can lead to addiction
 

a. Symptomatic relief of nasal d. pvd.


congestions
b. Prevention or reversing 145. methyl ergometrine is used in:
a. post partum haemorrhage.
hypotention accompany with
b. hypertension.
spinal anesthesia
c. induction of labour.
c. Control of urinary d. a and c.
incontinence
d. All of the above 146. All of the following are uses of
bromocriptine except:
141. Pseudoephedrine is similar to a. parkinsonism.
Ephedrine but : b. acromegaly.
c. hypertension.
a. With Less pressor and CNS
d. hyper prolactinaemia.
action
b. It cannot be given orally 147. the mechanism of action of
c. It causes urine retention ergotamine on alpha receptors is:
d. Non of the above a. antagonism.
b. partial agonism.
c. competitive inhibition.
142. alpha (d) methyl dopa is a: d. none of the above.
a. sympatholytic drug.
b. adrenolytic drug. 148. the ergot alkaloid used in
c. sympatomimetic drug. cerebral ischaemia is:
d. none of the above. a. dihydro ergotoxine.
b. ergotamine.
143. the most potent ergot al kaloids c. methyl ergometrine.
in B-receptor bloking is: d. all of the above
a. ergotamine.
b. ergometrine.
149. selective alfa 1- blocker include:
c. dihydro ergotoxine.
a. prazosion.
d. methyl ergometrine.
b. labetalol.
c. alpha methyl dopa.
144. ergotamine is used in: d. ergotamine.
a. hypertension.
b. acute attack of migraine. 150. the therap eutic uses of selective
c. alzheimers. alfa 1-blockers include:
 

a. hypertension. b. membrane stabilizing


b. benign prostatic hyperplasia. activity
c. peptic ulcer. c. central depressant effect
d. a and b. d. high lipid solubility

151. the adverse effects of selective 156. ……………… blocks both beta
alfa 1 blockers don't include: & alpha receptor:
a. syncope. a. prapanolol
b. failure of ejaculation. b. atenolol
c. hypertension. c. acebutalol
d. salt and water retention. d. carvedilol

152. the antihypertensive drug chosen 157. all of the following is a lipophilc
in pregnancy is: b-blocker except:
a. dihydroergotoxine. a. atenolol
b. alpha methyl l dopa. b. pindolol
c. drazosin. c. carvedilol
d. terazosin. d. labetalol

153. …………….. has a cardio 158. all of the following is true about
selective property: propranolol except:
a. atenolol. a. it has a membrane
b. propanolol. stabilizing action
c. pinodolol. b. it has a positive chronotropic
d. all of the above. effect
c. it can cross BBB
154. all of the following is true about
ISA except: 159. the mechanisms involved in
a. help in preventing heart lowering the B.P with the use of
failure. propranolol include:
b. caused by pindolol. a. lowering the cardiac output
c. Inclued exert signs of b. reduce rennin and
sympathetic stimulation. aldosterone
d. it is a beta antagonist action. c. reducing sympathetic
outflow
155. the antiarrhymic activity of some d. all of the above
beta blocker is due to:
a. ISA
 

160. the metabolic effect of a. atenolol and acebutalol


propranolol includes: b. atenolol and metoprolol
a. increased glucagon secretion c. acebutalol and metoprolol
b. hyperglycemia d. none of the above
c. hypoglycemia
d. anaemia True or false

161. the therapeutic uses of 166. propranolol cause


propranolol include: bronchodilation
a. effort induced angina
b. hypertension 167. quinidine like actions appears
c. cardiac arrhythmia only in high doses of propranolol
d. all of the above
168. heart block is a contraindication
162. The bradycharida caused by beta in beta blockers treatment
blockers is treated by:
a. digitalis 169. all beta blockers possess
b. atropine membrane stabilizing activity
c. pindolol
d. insulin

163. An important side effect of beta 2


blockade is:
a. heart failure
b. depression
c. symptomless hypoglycemic
coma
d. hypotension

164. The beta blocker used in


treatment of chronic glaucoma is:
a. pendolol
b. nadolol
c. atenolol
d. timolol

165. which of the following drugs has


local anaesthetic action:
 

Answers: 33. C

1. C 34. C

2. D 35. A

3. D 36. B

4. A 37. A

5. D 38. D

6. A 39. A

7. B 40. C

8. C 41. C

9. D 42. A

10. A 43. D

11. C 44. B

12. C 45. B

13. D 46. C

14. B 47. D

15. A 48. D

16. C 49. C

17. B 50. B

18. C 51. B

19. A 52. D

20. B 53. B

21. C 54. B

22. A 55. B

23. B 56. A

24. A 57. B

25. C 58. B

26. D 59. A

27. C 60. B

28. D 61. C

29. B 62. B

30. D 63. B

31. C 64. D

32. A 65. B
66. A
 

67. A 101. A
68. C 102. B
69. A 103. B
70. D 104. B
71. C 105. A
72. D 106. B
73. B 107. B
74. C 108. C
75. B 109. B
76. D 110. D
77. B 111. A
78. A 112. D
79. C 113. D
80. B 114. A
81. B 115. E
82. D 116. E
83. A 117. B
84. A 118. E
85. B 119. D
86. A 120. B
87. B 121. D
88. A 122. D
89. A 123. E
90. B 124. D
91. A 125. B
92. C 126. A
93. C 127. B
94. C 128. B
95. C 129. B
96. C 130. A
97. A 131. D
98. B 132. B
99. A 133. E
100. B 134. C
 

135. C 169. F
136. A
137. E
138. D
139. A
140. D
141. A
142. A
143. C
144. B
145. D
146. C
147. B
148. A
149. A
150. D
151. C
152. B
153. A
154. D
155. B
156. D
157. A
158. B
159. D
160. C
161. D
162. B
163. C
164. D
165. C
166. F
167. T
168. T
 
 

Chapter 2 : CNS a. Medulla oblongata


b. Mid brain
Physiology of CNS:
c. Spinal cord
d. Pons
1. Ability of the CNS to recognize the
type of the change it received is : 6. Which of the following does Pons
a. Integrative function have sensory and motor nerves to :
b. Sensory function a. Mouth
c. Motor function b. Neck
d. All of the above c. Throat
d. Face
2. Inner most layer of the meningies
is : 7. All of the following cranial nerves
a. Dura Mater emerge from the hind brain except
b. Pia Mater :
c. Arachnoid space a. III
d. Subarachnoid space b. V
c. VI
3. CSF exists in which of the d. VII
following :
a. Pia mater 8. All of the following are parts of the
b. Dura matar forebrain except :
c. Arachnoid layer a. Hypothalamus
d. Subarachnoid space b. Cerebrum
c. Cerebellum
4. Which of the following contains d. Thalamus
venous sinuses to drain CSF :
a. Pia mater 9. Grey matter is formed of :
b. Dura matar a. Myelin sheath
c. Arachnoid b. Nerve cell bodies
d. All of the above c. Nerve fibres
d. Dendrites
5. The most important vital centre is :
 

10. Which of the following part of 18. 12th Cranial nerve merges from
skin isn’t innervated by spinal medulla oblongata
nerves ? 19. Spinal cord passes through
a. Hand foramina transversorium of
b. Foot vertebrae
c. Face 20. There are 12 cranial nerves
d. Abdomen
21. The energy of the change in external
11. Deramatome is supplied by : or internal environment of the body is

a. Ventral root of spinal cord converted to nerve impulse by

b. Dorsal root of the spinal cord a. Detectors


b. Transducers
12. Blood brain barrier : c. Both of them
a. Controls rate by which d. Non of the above
substance passes from EC fluid
b. Controls kind of substances 22. Proprioceptors respond to
passing from EC fluid mechanical stimuli and located in

c. All of the above a. Muscle


b. Tendon
d. None of the above
c. Joint
True or false: d. All of the above

13. Blood brain barrier isn’t


23. In the aortic and carotid sinus
permeable to O2
there are mechanoreceptors called
14. Efferent nerve is considered the a. Stretch receptors
sensory nerve b. Proprioceptors
15. Diencephalon includes pituitary c. Baroreceptors
glands d. All of the above
16. Ridges in the surface of cerebral
cortex is called sulci 24. All of the following are
17. No of peduncles connected mechanoreceptors except

between each of cerebellar a. Touch


b. Stretch receptors
hemisphere and brain stem parts
c. Taste receptors
is 2
 

d. Baroreceptors d. Irris

25. Stretch receptors are located in the 30. The sensation perceived as a result
alveoli of the lung and .... of stimulation of a receptor is
a. Right atrium called
b. Left atrium a. Adequate stimulus
c. Both of them b. Modality of sensation
d. Aorta c. Action potential
d. Non of the above
26. The thermoreceptors that
stimulated by thermal form of 31. The method of stimulation affect
energy include warmth receptors on the type of sensation
only a. True
a. True b. False
b. False
32. ............ is the ability of the receptor
27. All of the following are chemical to respond to stimuli
receptors except a. Action potential
a. Taste receptors b. Adequate stimulus
b. Pressure receptors c. Excitabilty
c. Olfactory receptors d. All of the above
d. Glucoreceptors
33. The potential that result from
28. ............ stimulated by any form of opening of Na + channels in the
energy potent enough to cause receptor membrane is called
tissue damage a. receptor potential
a. Proprioceptors b. Generator potential
b. Barorecptors c. Graded potential
c. Stretch receptors d. All of the above
d. Nociceptors
34. An increase in the amplitude of
29. Electromagnetic receptors include the receptor potential produced by
: …….. stimulus intensity
a. Rods in retina a. Decreased
b. Cons in retina b. Increased
c. Both of them
 

c. No effect 39. The modality discrimination


depends on
35. The receptor potential has the a. Adequate stimulus
following properties except b. Area of brain activated
a. Local c. Both of them
b. Propagated d. Non of the above
c. No refractory period
d. No block by anaesthetics 40. .............. discrimination Depends on
the fact that each receptor has a
36. In adaptation all the following are specific pathway to the sensory
true except cortex where different parts of the
a. Increase number of nerve body are represented
impulses a. Modality
b. Constant maintaned stimulus b. Locality
c. decline in the amplitude of the c. Intesity
receptor potential d. Non of the above
d. decrease number of nerve
impulses 41. Discrimination of intensity also
depends on
37. All of the following are rapidly a. Frequency of discharge of
adapting receptors except action potentials
a. Touch b. number of receptors
b. Baroreceptors stimulated
c. Olfactory c. both of them
d. Non of the above d. non of the above

38. Coding of sensory information is 42. when you can determine your
the ability of the brain to position , it is a
discriminate the ........ of different a. Conscious proprioceptive
stimuli sensations
a. Modality b. Unconscious proprioceptive
b. Locality sensations
c. Intesity c. Tactile sensations
d. All of the above d. Non of the above
 

43. All of the following are from d. All of the above


Unconscious proprioceptive
sensations except 48. gracile and cuneate tracts
a. Movement of joints Transmits the following sensations
b. Muscle length except
c. Muscle tension a. Vibration sense
d. Non of the above b. Conscious proprioceptive
sensations
44. Crude touch is a touch sensation c. Fine touch
that is sharply localized and needs d. Pressure sense
a relatively strong stimulus to be
elicited 49. In Patients with lesions in the
a. True dorsal column pathway all of the
b. False following are true except
a. Loss of proproceptive
45. ............ is the ability to localize a sensations
touched cutaneous spot while the b. Cannot identify objects by
eyes are closed hands when eyes are closed
a. Tactile discrimination c. Identify their position when
b. Tactile localization eyes are opened
c. Stereognosis d. Knowing if their joints is in
d. Pressure sense flexion or extension

46. In Stereognosis. All of the 50. Ventral spinothalamic tract


following are true except Transmits the following sensations
a. Recognize an object by touch except
b. Eyes are opened a. Vibration sense
c. Recognize an object by size b. Crude touch
d. Recognize an object by weight c. Pressure sense
d. Itch and tickle
47. ……… Results from rapidly
repetitive sensory signals from 51. Mechanoreceptive sensations are
tactile receptors transmitted by the following
a. Pressure sense pathways except:
b. Itch and tickle sensations a. Dorsal column lemniscal
c. Vibration sense pathway
 

b. Lateral spinothalamic tract d. Ventral spinocerebellar tract


c. Ventral spinothalamic tract
d. Ventral spinocerebellar tract 55. Crude touch is transmitted by
………..
52. All of the following sensations are a. Dorsal column lemniscal
transmitted by dorsal column pathway
lemniscal pathway except: b. Lateral spinothalamic tract
a. Stereognosis c. Ventral spinothalamic tract
b. Vibration sensation d. Ventral spinocerebellar tract
c. Joint movements and position
d. Pressure sensation 56. Proprioceptive sensations are
transmitted by
53. All of the following are true a. Dorsal column lemniscal
concerning the dorsal column pathway
lemniscal pathway except: b. Ventral spinothalamic tract
st
a. 1 order neuron pass to the c. Ventral spinocerebellar tract
dorsal white column of the d. a and c
spinal cord
b. Fibers from the upper part of 57. the 1st order neuron in the
the body ascend in the medial spinocerebellar pathway are thick
part of the dorsal white column myelinated A delta fibers which
forming the fasiculus gracilis relay in the clark’s column at the
c. Medial lemnicsus terminate in base of the dorsal horn of the
the thalamus spinal cord
d. 3rd order neuron terminate in a. true
the sensory cortex b. false

54. Astereognosis results from lesion 58. 2nd order neurons of the dorsal
in the ………. spinocerebellar tract ascend in the
a. Dorsal column lemniscal anterolateral white column of the
pathway spinal cord reaching the medulla
b. Lateral spinothalamic tract a. True
c. Ventral spinothalamic tract
 

b. False
63. Which type of the following fibers
59. All of the following terminate in transmit deep pain?
the sensory cortex except: a. Non myelinated A fibers
a. Dorsal column lemniscal b. Myelinated B fibres
pathway c. Non Myelinated C fibers
b. Ventral spinothalamic tract d. Myelinated C fibers
c. Ventral spinocerebellar tract
d. Lateral spinothalamic tract 64. All of the following participates in
the muscle ischaemic pain except :
60. 2nd order neurons of the ventral a. Arterial occlusion
spinocerebellar tract pass through b. Maintained muscle relaxation
the superior peduncle to reach the c. Increase in Lewis P factor
vermis while those of the dorsal d. Trauma of the deep structures
tract pass through the inferior
peduncle 65. All of the following have fast rate
a. True of transmission of the pain except
b. False a. Parietal layer of pericardium
b. Parietal layer of pleura
61. All of the following have receptors c. Brain
to stimulate the deep pain except d. Parietal layer of peritoneum
a. Muscles
b. Tendons 66. All of the following are properties
c. Joints of the visceral pain except
d. Skin a. Dull aching
b. Radiates to the other structures
62. Ischemia of the muscle is c. Sharp
produced in the deep pain due to : d. Poorly localized
a. Prolonged muscle contraction
b. Prolonged vasoconstriction of 67. One of the following its afferent is
blood vessels vagus nerve:
c. Sympathetic effects a. Colon
d. Hypertension b. Urinary bladder
 

c. Rectum c. 6
d. Trachea d. 8

68. All of the following are properties 73. The somatosensory cortical areas
are located in the ....... lope
of the referred pain except :
a. Frontal
a. Can be felt in diseased viscus
b. Temporal
only
c. Parietal
b. Felt away from its original site
d. Occipital
c. Referred to somatic structure
with the same origin as viscus
74. Somatic sensory area I occupies
d. Felt in the dermatomes the brodman’s areas

69.The cerebral cortex contains a. 1,2,3


............. neurons b. 2,3,5

a. 100 milion c. 1,3,5

b. 100 bilion d. 5,7

c. 100 thousands
d. Non of the above 75. In somatic sensory area I all of the
following are true except
a. The foot & leg are represented
70.The cerebral cortex is composed of
medially
....... hemispheres
b. The lips & fingers occupy smaller
a. 2
areas than the trunk
b. 4
c. This area show modality
c. 6
separation of different sensation
d. 8
d. It receives sensations from the
opposite side of the body
71.The surface of each hemispheres is
formed of elevations called gyri
76. somatic sensory area I act as a
a. True
centre for the perception of the
b. False
following sensations except
a. stereognosis
72. Each hemisphere in cerebral
b. vibration sense
cortex contains........... Lobes
c. discrimination of weights
a. 2
d. pain
b. 4
 

77. The representation of the different 82. The mechanism of primary


parts of the body in the somatosensory hyperalgesia depends on
area II is much more sharp than in a. vasodilatation
somatosensory area I b. lowering the threshold of pain
a. true receptors
b. false c. both of them
d. non of the above
78. somatosensory area II receive .........
fibres from the spinothalamic than the 83. All of the following reduce pain
dorsal column pathway except
a. more a. rubbing
b. less b. electrical stimulation of certain
c. long areas of the brain
d. short c. the absence of receptors for
opiates in the brain
79. the patient with damage in d. acupuncture 
brodman’s areas 5 , 7 can recognize
84. The neurotransmitter act on
objects by touch
postsynaptic neuron to
a. true
modify its activity either
b. false
exciting or inhibiting

80. Area of flare that surrounds an according to the nature of the


inflammed or injured skin area is the postsynaptic receptors.
site of occurring
a. True
a. primary hyperalgesia
b. False
b. secondary hyperalgesia
c. analgesia 85. The threshold for the
d. hypoalgesia postsynaptic neuron
excitation is about
81. Releasing of ....... from the injured
skin area to neighbouring healthy skin a. -59 mv
cause primary hyperalgesia except b. -70 mv
a. serotonin c. -50 mv
b. histamine 86. gamma aminobutyric acid is
c. proteolytic enzymes :
d. kinins
 

a. an excitatory neurotransmitter a. increases the permeability of


b. an inhibitory neurotransmitter the postsynaptic membrane to
c. inhibits the release of the K+ / Cl
excitatory transmitter from the b. increases the degree of
excitatory presynaptic fiber. intracellular negativity
d. Both a and c c. leading to a state of
e. Both b and c hyperdepolarisation
87. Binding of the excitatory
transmitter to postsynaptic 90. stimulation of several
receptors increases the presynaptic fibers on the
permeability of the postsynaptic neuron at the
postsynaptic membrane to sametime to raise the
a. Na only postsynaptic membrane
b. K only potential to the threshold
c. K and CL level is called:
d. all ions a. Temporal summation
88. All of the following are b. Spatial summation
correct about The EPSP
except: 91. Which of the following
a. propagating properties serves in cessation
b. lasts for about 15 of an epileptic fit:
milliseconds. a. Synaptic delay
c. A single EPSP is not enough to b. Synaptic fatigue
increase the neuronal c. Post-tetanic facilitation
potential to threshold value d. Summation
instead it must add up to
trigger an action potential. 92. Which of the following
properties serves in the recall
89. Which of the following is of information after a short
incorrect about Electrical time of its reading:
events in inhibitory synapses: a. Synaptic delay
b. Synaptic fatigue
c. Post-tetanic facilitation
 

d. Summation d. accumulation of ions in


93. coma in uraemic patients is the synaptic cleft
mainly due to :
a. acidosis that has inhibitory
True or false:
effect on synaptic
transmission 96. Nuclear chains have sensory
b. alkalosis that has inhibitory innervations by primary and
effect on synaptic secondary fibers while the nuclear
transmission bags are innervated by primary
c. acidosis that has excitatory fibers only
effect on synaptic 97. Motor fibers innervate the central
transmission receptor areas of intrafusal fibers
d. acidosis that has excitatory while the sensory fibers innervate
effect on synaptic the peripheral contractile parts of
transmission the intrafusal fibers
98. Nuclear bags are supplied by
94. if the cerebral circulation is static gamma efferents while the
temporarily interrupted for nuclear chains are supplied by
3-6 seconds that may lead to dynamic gamma efferents
a. death 99. Gamma motor neurons are the
b. loss of consciousness centers of stretch reflex
c. epilepsy 100. The dynamic response of the
primary sensory endings informs
95. caffeine enhance synaptic the CNS about the rate of muscle
transmission by (choose the stretch while the static response of
best answer): the secondary sensory endings
a. increasing the discharge of informs the CNS about the
neurotransmitters amount of stretch
b. decreasing fatiguability of
the nerve 101. All of the followings
c. decreasing the threshold concerning the nuclear bags are
for excitation of neurons true except:
 

a. Are innervated by primary d. Flexors of the neck


sensory fibers
b. Are innervated by dynamic 105. The muscle tone increases in
gamma fibers cold weathers while it decreases
c. Their stretch gives information in hot weather
about the amout of stretch a. True
d. They are rapidly adapting b. False
receptors
106. All of the following is true
102. ………… increase gamma concerning the muscle tone
fibers discharge : except:
a. Anxiety a. The receptor is rapidly
b. Painful cutaneous stimulation adapting
c. Hooking of fingers together b. The afferent fibers are
d. All of the above secondary while the motor
fibers are alpha motor fibers
103. All of the following are true c. The effectors are extrafusal
concerning the stretch reflex fibers
except: d. It’s responsible for
a. Its total time is short maintaining the erect posture
b. There is no irradiation or against gravity
fatigue
c. There is after discharge due to 107. All of the following is true
the presence of the concerning the tendon jerk
interneurons except:
d. There is reciprocal a. The receptor is rapidly
innervations adapting
b. The afferent fibers are
104. All of the following are primary while the motor
antigravity muscles except: fibers are alpha motor fibers
a. Flexors of the upper limb c. The effectors are intrafusal
b. Extensors of the lower limb fibers
c. Extensors of the back
 

d. It’s responsible for diagnosing c. Stimulated muscle spindles


neurological disorders cause stimulation of the
antagonistic muscle via
108. All of the following is true inhibition of the alpha motor
concerning clast knife spasticity neuron supplying the over
except: stretched muscle
a. It’s upper motor neuron d. It’s a protective reflex
lesion protecting the muscle from
b. It’s example of hypertonia tearing as a result of over
c. There is exaggerated tendon stretch
jerks
d. There is no tendon jerks 111. Clonus occurs as a result of
stretch reflex-inverse stretch
109. All of the following are reflex sequence resulting in
inhibitory centers of stretch reflex alternating mucles contractions
except: and relaxations
a. Paleocerebellum a. True
b. Inhibitory reticular formation b. False
center
112. the primary motor area is
c. Basal ganglia
found in:
d. Primary motor area of the a. frontal lope
cortex b. parietal lope
c. temporal lope
110. All of the following is true d. occipital lope

concerning the inverse stretch


113. all of the following are parts of
reflex except:
the temporal lope except:
a. It’s relaxation of the over
a. auditory centre
stretched muscle b. auditory association area
b. It occurs by stimulation of the c. hippocamus
inhibitory interneurons which d. brocas area
stimulate the antagonistic
muscle
 

114. the area occupying the


precentral gyrus in the frontal 119. the following areas sharing in
lope is: planning of voluntery movements
a. premotor area except:
b. primary motor area a. premotor area
c. supplementary motor area b. primary motor area
d. suppresor area c. supplementry motor area
d. prefrontal association area
115. all of the following are
bilateraly represented in the brain 120. area 6 inhibits all of the
except: following except:
a. upper part of the face a. gross movements
b. lower part of the face b. spinal reflexes
c. abdominal wall muscles c. muscle tone
d. respiratory muscle d. grasp reflex

116. the cells presented in the 121. the area responsible for
primary motor area are: conjugate eye movements is:
a. betz cells a. brocas area
b. martinotti cells b. head rotation area
c. horizontal cell of cajal c. frontal eye field
d. none of the above d. exners area

117. the area responsible for 122. motor apraxia is a lesion of:
initiating delicate voluntery a. brocas area
movements is; b. head rotation area
a. supplementary area c. frontal eye field
b. supressor area d. area of hand skills
c. primary motor area
d. premotor area 123. brocas area is essential for:
a. walking
118. area 4 and 6 share the b. speech
function of: c. involuntery movements
a. initiation of delicate d. muscle tone
movements
b. facilitation of spinal reflexes 124. the area lying between area 4
c. inhibition of spinal reflex and 6 is:
d. initiation of gross movements a. supplementary motor area
 

b. prefrontal association area 132. All of the following are


c. suppressor area considered direct tracts except :
d. none of the above a. Corticospinal tract
b. Corticobulber tract
125. all of the following are
c. Corticonuclear tract
function of the prefrontal
association area except; d. Rubrospinal tract
a. provide the ability to
concentrate 133. Most of the corticospinal tracts
b. plays arole in immediate are :
memory
a. Anterior
c. control behaviour
b. Lateral
d. initiate fine movements
c. Ipsilateral

126. the area responsible for d. Medial


elaboration of thoughts is:
a. primary motor area 134. All of the following have
b. broadmanns areas 9:14 bilateral parts in the motor center
c. premotor area
except :
d. suppresor area
a. Upper face

127. the most excitable area of the b. Intercostal muscles


following is: c. Abdominal wall
a. primary motor area d. Back muscles
b. premotor area
c. suppresor area 135. Which of the following is
d. supplementary motor area
supplied by the corticobulber
tract :
TRUE OR FALSE
128. the premotor area gives origin a. Head
to pyramidal tracts. b. Hand
129. motor area 4 is responsible c. Foot
for delicate voluntery movements. d. Abdomen
130. motor apraxia is a lesion of
brocas area.
136. The corticonuclear tract arises
131. motor area 6 is responsible
from the motor centre :
for facilitation of spinal reflexes.
a. 4
 

b. 6 141. Which of the following is


c. 8 concerned with audiospinal
d. 10 reflexes ?
a. Medial tectospinal
137. All of the following tracts pass b. Lateral tectospinal
to the basal ganglia except : c. Rubrospinal tract
a. Rubrospinal tract d. Lateral reticulospinal tract
b. Corticospinal tract
c. Olivospinal tract 142. All of the following are
d. Tectospinal tract considered to be short tracts
except :
138. Indirect pathway most of it is : a. Olivospinal tract
a. Crossed b. Tectospinal tract
b. Uncrossed c. Rubrospinal tract
c. Excitatory d. Reticulospinal tract
d. Long
143. All of the following facilitates
139. All of the following occupy the the muscle tone except:
pyramid in medulla oblongata a. Lateral reticulospinal tract
except : b. Medial reticulospinal tract
a. Corticospinal tract c. Olivospinal tract
b. Tectospinal tract d. Vestibulospinal tract
c. Corticonuclear tract
True and false :
d. Corticobulbar tract
144. Most of pyramidal tracts are
140. Where does the rubrospinal crossed
tract join the corticospinal ? 145. Most of extra pyramidal are
a. Lateral column inhibitory
b. Medial colum 146. Pyramidal tracts are earlier in
c. Dorsal horn life
d. Ventral horn 147. Cortical control of pyramidal is
wider
 

148. Pyramidal occupy olive of 155. Hypertonia occurs due to the :


spinal cord a. Sparing for inhibitory
149. Extrapyramidal fibres descending tracts
decaussate at the lower border of b. Loss of the crossing inhibitory
the medulla oblongata tracts
150. Pyramidal are most important c. Intact inhibitory tracts
in the equilibrium d. Lesion in uncrossed excitatory
151. Extrapyramidal are concerned tract
with body posture
156. Injury in cranial nerve nuclei
152. All of the following are causes causes :
of lower motor neuron lesion a. LMNL
except : b. UMNL
a. Anterior horn cell c. Both
b. Somatic nerve d. None
c. Cranial nerve nuclei
True or false about UMNL :
d. Motor cortex
157. Localized paralysis
153. One of the following is correct 158. Lesion in higher centres
about LMNL : 159. Atonia
a. Accompanied by widespread 160. Normal Deep reflex
paralysis 161. Positive Babriniski
b. Due to lesion in motor cortex
162. The striatum is ………….
c. Deep spinal reflex is lost
a. Caudate and globus pallidus
d. No muscle wasting
b. Caudate and putamen
c. Globus pallidus and putamen
154. Positive Babiniski test includes
:
163. The receiving center of the basal
a. Planter flexion of the toes ganglia is …………
b. Dorsiflexion of all toes
a. Caudate and putamen.
c. Fanning of 4 smaller toes only
b. Globus pallidus
d. None of the above
c. Globus pallidus and putamen
 

a. Excitatory, prevent the


164. The discharge center of the unwanted involuntary
basal ganglia is …………. movement.
a. Caudate and putamen b. Inhibitory, facilitate the target
b. Globus pallidus and putamen movement

c. Globus pallidus c. Excitatory, facilitate the target


movement
165. Strioto-pallidal projection d. Inhibitory, prevent the
utilizes ……….. as a unwanted involuntary
neurotransmitter movement
a. GABA
169. Glutamate is released from
b. ACL
………….
c. Dopamine
a. Cortex
d. Glutamate
b. Striatum

166. Nigro-striatal projection utilizes c. Globus pallidus


……….. as a neurotransmitter d. Thalamus
a. GABA
170. The hyperkinetic features of
b. ACL
Parkinsonism are all except
c. Dopamine
……..
d. Glutamate
a. Brady kinesia and akinesia
b. Tremors
167. Globus pallidus may project to
all except ……….. c. Rigidity

a. Thalamus
171. We can use dopamine is
b. Subthalamus treatment of Parkinsonism
c. Brain stem a. True
d. Striatum b. False

168. The direct circuit is ……… and 172. Sensation can be consciously
its importance is …………
perceived by the cerebellum
a. true
b. false
 

173. The part of the cerebellum d. Servocomparator function…


concerned mainly with cerebrocerebellum
equilibrium is:
a. archicerebellum 177. Which of the following centers
b. paleocerebellum is responsible for the
c. Neocerebellum coordination of movement
during writing ?
174. Output from the a. Vestibulocerebellum
cerebrocerebellum passes b. Cerebrocerebellum
a. through the fastigial nucleus c. Spinocerebellum
then to the brain stem
b. To the dentate nucleus and 178. The following center is
then to the ventrolateral important for preventing the
nucleus of the thalamus decomposition of the movement
c. to emboliform and globose, :
then to the brainstem. a. Vestibulocerebellum
b. Cerebrocerebellum
175. the limbs & head are c. Spinocerebellum
represented in the vermis of the
spinocerebellum 179. The cerebrocellebellum has a
a. True leading role in all the following
b. False actions except:
a. Timing of movements
176. To stop the movement precisely b. coordinates the automatic
at the intended point by associated subconscious
subconscious signals is called movements
…...and it's achieved by …… c. Planning of movements
a. Servocomparator function… d. Prediction of movements
spinocerebellum
b. Damping of movement… 180. The flocculonodular lobe is
spinocerebellum considered as:
c. Damping of movement… a. Vestibulocerebellum
cerebrocerebellum b. Cerebrocerebellum
 

c. Spinocerebellum between it and the bony


labyrinth
181. The following tracts are a. True
involved in the process of b. False
maintaining the equilibrium
through the vestibulocerebellum 185. The macula of ……. is
except : concerned with equilibrium
a. reticulospinal a. Utricle
b. vestibulospinal b. Saccule
c. tectospinal
186. The macula of ……… is
182. The output of the cerebellum is concerned with vertical linear
generally excitatory to muscle acceleration while the macula of
tone ……. is concerned with
a. True horizontal linear acceleration
b. False a. Utricle / Saccule
b. Saccule / Utricle
183. Which of the following
statements is incorrect about 187. All of the following are
The vermis syndrome: stimulants to the SCC except:
a. the flocculo-nodular lobe is a. Caloric stimulation
affected b. Rotation
b. Symptoms are often absent c. Faradic stimulation
when the child is lying down d. Vestibular neuritis
c. There is nystagmus
d. There is hypotonia 188. SCCs are active at …………..
e. There is raised intracranial a. The beginning of rotation
pressure b. The end of rotation
c. Both of them
184. The perilymph is present within d. None of the above
the membranous labyrinth
while the endolymph is present
 

True or false: 196. All of the following are from the


autonomic changes that result
189. Sudden forward horizontal from stimulation of SCC except
movement results in a. Nausea
displacement of the otoconia b. Vomiting
forwards stretching all the hair c. Bradycardia
cells of the macula d. Hypertension
190. Stereocilium is located at one
side of the hair cell 197. In stimulation of SCC , muscle
191. In case of horizontal SCC tone changes help to
a. Support the posture during
displacement of the cupula
rotation
towards the utricle the crista
b. Guard against falling down
becomes stimulated
towards the activated side
192. The kinocilium of the superior
c. Cause motion sickness
SCC lies towards the utricle d. Both a & b
193. In the start of rotation from
right to left the endolymph 198. Stimulation of reticular
moves in the same direction but formation in the brain stem can
after 30 sec. in starts to move in cause bradycardia

the opposite direction a. True


b. False
194. When the individual starts to
rotate in horizontal plane from 199. ........... is the sensation of rotation
left to right , the endolymph in the absence of actual rotation
moves in the same direction a. Autonomic changes
a. True b. Muscle tone changes
b. False c. Vertigo
d. All of the above
195. SCC are active only at the
beginning and ending of 200. All of the following can cause
rotation or if rate or direction of vertigo except
rotation is changed
a. Motion sickness
a. True
b. Chronic alcoholism
b. False
c. Errors of refraction
 

d. Beginning of rotation a. True


b. False
201. .............is repetitive rhythmic
movement of the eye observed at 206. Rapid component of nystagmus
the start of rotation is controlled by brainstem
a. Vertigo circuits
b. Rotatory nystagmus a. True
c. Post rotatory nystagmus b. False
d. All of the above
207. When you look from a window
202. .............is repetitive rhythmic of a rapidly moving car ,it
movement of the eye observed at considers as
the end of period of rotation a. Physiological nystagmus
a. Vertigo b. Pathological nystagmus
b. Rotatory nystagmus c. Optokinetic nystagmus
c. Post rotatory nystagmus d. Both a & c
d. All of the above
208. Slow component of nystagmus
203. Angular acceleration is one of occurs when the vestibular
the pathological causes of nucleus discharges in secondary
nystagmus direction
a. True a. True
b. False b. False

204. All of the following are from the 209. Output from other thalamic
pathologic causes of nystagmus nuclei passes to be regulated
except
before reaching the cortex.
a. Cerebellar diseases
a. The medial group of nuclei
b. Inner ear disorders
b. The reticular nuclei
c. Optokinetic nystagmus
c. The intralaminar nuclei
d. Defective vision

205. In slow component of 210. All of the following statements


nystagmus both eyes move are correctly describing the
toward the same direction of intralaminar nuclei except
rotation
 

a. scattered along the internal c. 3


medullary lamina,
b. They are connected with the 213. lateral part of the structure 3
reticular activating system. recieves :
c. It receives fibers carrying slow a. medial leminiscus
pain and thermal sensation b. trigeminal leminiscus
d. Site of relay of the c. input from the basal ganglia
neospinocerebellar tract
e. It is one of the Nonspecific 214. all of the following statements
thalamic-nuclei about the medial geniculate
body are true except:
211. Both the anterior and medial a. projects auditory impulses to
groups of thalamic nuclei the temporal lobe
receive impulses from the b. connected to inferior colliculus
hypothalamus and have a role in c. one of the Posterior group of
controlling emotions thalamic nuclei
a. True d. connected to superior
b. False colliculus

Notice the following picture and


215. The structure A is related to the
answer the questions:
integration of somatic, visual
and auditory information.
a. True
b. False

216. Which of the following isn't one


of the functions of the thalamus

212. Which of the pointed nuclei is a. It is a relay center in circuits of

the Main thalamic motor the basal ganglia.

nucleus b. It is a relay center for visual

a. 1 and auditory pathways

b. 2
 

c. It is a relay center for epicritic cann't identify a pen in his


sensations from the opposite …hand with closed eyes
side of the body to the cortex a. right
d. It is a primitive center for b. left
protopathic sensations from
the same side of the body 221. All of the following are
functions of the anterior
217. The most affected part in the hypothalamus except:
thalamic syndrome is: a. Regulation of body
a. medial division of the temperature
posteroventral nucleus b. Water balance
b. lateral division of the c. Controlling of sleeping
posteroventral nucleus d. Wakefulness
c. lateral ventral thalamic nuclei
d. anterior-nuclei 222. Destruction of the 2
ventromedial nuclei of
218. what's meant by the thalamic hypothalamus leads to:
hyperpathia: a. Hypothalamic obesity
a. the pain felt is following the all b. Hyperphagia
or nothing relationship c. Sham rage reaction
b. the pain felt is poorly localized d. all of the above
c. the pain felt is Having a high
threshold 223. Endocrine functions are
controlled by……………..nuclei
219. patient suffering from thalamic of hypothalamus:
syndrome may have sensory and a. Anterior group
motor ataxia b. Posterior group
a. true c. Medial group
b. false d. Lateral group

220. patient suffering from 224. Bilateral amagdaloid lesion leads


thrombosis of the artery to:
supplying the right thalamus a. Placidity
 

b. Sham rage reaction b. Supraoptic nucleus


c. Aphagia c. suprachiasmic nucleus
d. None of the above d. None of the above

225. Stimulation of ventromedial 230. Thirst centre is stimulated by:


nuclei of hypothalamus leads to: a. Increased blood volume
a. Aphagia b. Decreased osmolarity
b. Anorexia c. Decreased blood volume
c. Placidity d. None of the above
d. Both A and c
231. Cells of supraoptic nucleus are
226. Placidity can be produced by: sensitive to:
a. Stimulation of ventromedial a. Temperature
nuclei b. Blood volume
b. Bilateral lesion of amygdaloid c. Osmolairty
c. Removal of neocortex d. B & c
d. Both a & b
232. Sleep is mediated by:
227. Central thermo receptors a. Cholinergic neurons
present in: b. GABA releasing inhibitory
a. Supraoptic nucleus neurons
b. Preoptic nucleus c. Histaminergic neurons
c. Suprachiasmic nucleus d. None of the above
d. None of the above
233. Arousal is produced by:
228. Feeding center presents in: a. Inhibition of reticular
a. Anterior nuclei formation
b. Posterior nuclei b. Stimulation of anterior
c. Medial nuclei hypothalamus
d. Lateral nuclei c. Stimulation of posterior
hypothalamus
229. Thirst center presents in: d. None of the above
a. Preoptic nucleus
 

234. …… center is present in 239. mamillothalamic tract connects:

ventromedial nucleus: a. lateral nuclei of the thalamus and


mamillary bodies
a. Thirst center
b. anterior nuclei of the thalamus
b. Feeding center and mamillary bodies
c. Satiety center c. lateral nuclei of the
d. None of the above hypothalamus and mamillary
bodies
d. anterior nuclei of the
235. Stimulation of anterior hypothalamus and mamillary
hypothalamus leads to: bodies
a. Sleeping
240. which of the following is the
b. Sedation
correct sequence of the papez
c. Arousal circuit
d. None of the above a. Hippocampus >> Cingulate
gyrus >>Anterior thalamus >>
Mamillary bodies
236. Anorexia results from:
b. Anterior thalamus >>Mamillary
a. Stimulation of feeding center bodies >>
b. Destruction of satiety center Hippocampus>>Cingulate gyrus
c. Stimulation if satiety center c. Hippocampus >> Anterior
thalamus >> Mamillary bodies
d. Destruction of feeding center
>>Cingulate gyrus
d. Hippocampus >>Mamillary
237. Aphagia results from bodies >>Anterior thalamus
a. Stimulation of feeding center >>Cingulate gyrus

b. Destruction of satiety center


c. Stimulation of satiety center 241. the fornix connects:
d. Destruction of feeding center a. The hippocampus to the
mamillary bodies
b. Hippocampus to the Anterior
238. Destruction of satiety center thalamus
leads to: c. Mamillary bodies to the Cingulate
a. Hyperphagia gyrus

b. Aphagia
c. Anorexia 242. Its lesions cause moderate

d. None of the above hyperphagia with indisciminate


ingestion of all kinds of food
 

a. hippocampus d. They are with amplitude of


b. Cingulate gyrus about 50 μV
c. mamillary bodies
d. amygdale
247. The following waves are
markedly seen in patients with
243. a structure is concerned with the
brain diseases:
formation and storage of memories
a. theta waves
associated with fear and love
a. hippocampus b. Beta waves
b. Cingulate gyrus c. Delta waves
c. mamillary bodies d. a & c
d. amygdaloid nucleus e. b & c

244. The limbic system and the 248. Which of the following
hypothalamus can play a role in statements is true regarding to
regulating our autonomic
the Beta waves?
functions
a. are seen in the parietal region
a. true
b. Are recorded in an awake
b. false
person regardless the mental
245. the following are functions of the activity.
limbic system except c. They have amplitude lower
a. Motivation than 50 mV
b. Olfaction
c. relay center for visual and d. They are not recorded during
auditory pathways sleep
d. Regulation of autonomic e. None of the above
functions
249. Which of the following
246. All the following are true statements is false about the
regarding to the alpha waves Theta waves?
recorded by the EEG except: a. They have frequency less than
a. are most marked in the that of Alpha waves
parieto-occipital lobe b. Physiologically, the occur in
b. Are recorded in an awake children
active person c. Pathologically, they are seen in
c. Occurring at frequency of 8- many brain disorders
13/sec d. They are seen during stage I of
slow wave sleep
 

e. None of the above 253. REM sleep is characterized by:


a. Atonia
250. Regarding to the Delta waves, b. Variable heart rate
which of the following c. Active dreaming
statements is false? d. a & b
a. they have the lowest frequency e. None of the above
of EEG waves
b. They are recorded only in 254. Which of the following
stage III of slow wave sleep statements about REM sleep is
c. Normally, they occur in false:
infancy a. It shows activity similar to the
d. They are the waves of very waking state.
deep sleep b. Apnea may occurs in this stage
e. None of the above due to reduction in the
homeostatic mechanism
251. Slow wave sleep is characterized c. The Beta waves are mainly
by the following EXCEPT: recorded in this stage & other
a. Drop in the blood pressure slow waves are also recorded.
b. Decrease in the BMR
c. Sympathetic tone on the blood d. Known as paradoxical sleep
vessels is lowered and occurs in episodes of 5-
30min
d. This is the stage of no dreams e. None of the above
e. None of the above
255. Each of the following produce
252. Regarding to the NREM sleep, all sleep EXCEPT:
of the following are false EXEPT: a. Adenosine
a. It occurs at the beginning of b. GABA
the sleep. c. Serotonin antagonists
b. the passage from wakefulness d. None of the above
to it is characterized by an
increase in frequencies and Put (True) or (False) in front of the
voltage activities following statements (from 11-15):
c. It is of duration less than REM 256. Stage II of the NREM sleep is
sleep characterized by sleep spindles
d. a &b superimposed on Beta waves.
e. None of the above 257. NREM sleep is characterized by
marked decrease in muscle tone.
 

258. REM sleep is known as


paradoxical sleep and shows
only Beta waves.
259. The sleep cycle consists of one
episode of REM and 4 episodes
of NREM.
260. During REM sleep, the slow
waves are inhibited by
cholinergic neurons in the
brainstem.
 

Answers: 32. C
33. D
1. B
34. B
2. B
35. B
3. D
36. A
4. B
37. B
5. A
38. D
6. D
39. C
7. A
40. B
8. C
41. C
9. B
42. A
10. C
43. A
11. B
44. B
12. C
45. B
13. F
46. B
14. F
47. C
15. F
48. D
16. F
49. D
17. F
50. A
18. T
51. B
19. F
52. D
20. F
53. B
21. B
54. A
22. D
55. C
23. C
56. D
24. C
57. B
25. A
58. B
26. B
59. C
27. B
60. A
28. D
61. D
29. C
62. A
30. B
63. C
31. B
64. B
 

65. C 98. F
66. C 99. F
67. D 100. T
68. A 101. C
69. B 102. D
70. A 103. C
71. A 104. D
72. B 105. T
73. C 106. A
74. A 107. C
75. B 108. D
76. D 109. D
77. B 110. C
78. A 111. A
79. B 112. A
80. B 113. D
81. A 114. B
82. C 115. B
83. C 116. A
84. A 117. C
85. A 118. D
86. D 119. B
87. D 120. A
88. A 121. C
89. C 122. D
90. B 123. B
91. B 124. C
92. C 125. D
93. A 126. B
94. B 127. A
95. C 128. F
96. T 129. T
97. F 130. F
 

131. F 164. C
132. D 165. A
133. B 166. C
134. D 167. D
135. A 168. C
136. C 169. A
137. B 170. A
138. B 171. B
139. B 172. B
140. A 173. A
141. A 174. B
142. D 175. B
143. A 176. B
144. T 177. C
145. T 178. B
146. F 179. B
147. F 180. A
148. F 181. C
149. F 182. A
150. F 183. D
151. T 184. B
152. D 185. B
153. C 186. B
154. D 187. C
155. B 188. C
156. A 189. F
157. F 190. F
158. T 191. T
159. F 192. F
160. F 193. F
161. T 194. B
162. B 195. A
163. A 196. D
 

197. D 230. C
198. A 231. D
199. C 232. B
200. D 233. C
201. B 234. C
202. C 235. A
203. B 236. D
204. C 237. C
205. B 238. A
206. A 239. B
207. D 240. D
208. B 241. A
209. B 242. D
210. D 243. D
211. A 244. A
212. B 245. C
213. A 246. B
214. D 247. C
215. A 248. C
216. D 249. E
217. B 250. B
218. A 251. D
219. A 252. A
220. B 253. D
221. D 254. C
222. D 255. D
223. A 256. F
224. A 257. F
225. D 258. T
226. D 259. F
227. B 260. T
228. D
229. B
 

Anatomy of the CNS: c. Superior petrosal sinus in the


attached margin.
I. Anatomy of head and neck: d. Transverse sinus in the
attached margin.

1. From the attachment of falx 5. from the single sinuses found in


cerebri all except ……… the cranial cavity are all except
a. crista galli. ……
b. Upper surface of tentorium a. Superior sagittal.
cerebelli. b. Inferior sagittal.
c. to the lips of the sagittal sulcus c. Straight sinus.
on the inner aspect of skull d. Cavernous
cap.
d. Upper border of petrous 6. from the paired sinuses are all
temporal bone except ………
a. Superior petrosal.
2. Venous sinuses found in falx b. Inferior petrosal.
cerebri all except ……… c. Occipital
a. Superior sagittal sinus d. Transverse sinus.
b. Inferior sagittal sinus
c. Superior petrosal sinus 7. It begins at the apex of falx cerebri
d. Straight sinus above the crista galli and ends a
little to the right of the internal
3. The attached margin of Tentorium occipital protuberance by turning
cerebelli is attached to all except to the right side and becoming the
………. right transverse sinus. This is ……
a. crista galli. a. superior sagittal
b. posterior clinoid process b. inferior sagittal
c. upper border of petrous c. straight
temporal bone d. transverse
d. the margin of the groove for
transverse sinus. 8. Uniting with the great cerebral
vein to form the straight sinus this
4. Venous sinuses related to is ….
tentorium are all except ……… a. superior sagittal
a. Straight b. inferior sagittal
b. superior sagittal c. straight
d. transverse
 

9. It is situated at the line of junction


of the falx cerebri with the 14. blue eye is caused by bleeding in:-
tentorium cerebelli this is ………. a. aponeurosis of occipitofrontalis
a. superior sagittal muscle
b. inferior sagittal b. periosteum
c. straight c. dense C.T
d. transverse d. loose connective tissue

10. at the roof of the cavernous sinus 15. which of the following is a branch
there is ………. from the internal carotid artery:-
a. internal carotid artery a. supra orpital artery
b. Body of sphenoid b. superficial temporal artery
c. Pituitary gland c. posterior auricular artery
d. temporal lobe of the brain d. occipital artery

11. nerves found at the lateral wall of 16. the area of the scalp in front of the
the cavernous sinus are all except auricle is supplied by all of the
…….. folowing except:-
a. a.Oculomotor (III) a. supra orpital artery
b. trochlear (IV b. supra trochlear artery
c. abducent (VI) c. occipital artery
d. d.Maxillary (V2) d. superficial temporal artery

12. The dense connective tissue layer 17. the motor nerve to the
of the scalp is called:- preauricular part of the scalp is:-
a. Peripheral layer. a. posterior auricular nerve
b. Fatty layer b. temporal branch of fascial nerve
c. Vascular layer c. trigimenal nerve
d. Central layer d. maxillary nerve

13. The third layer of the scalp is the 18. the occipitofrontalis muscle is
aponeurosis of:- supplied by:
a. buccinator muscle a. temporal branch of fascial nerve
b. occipitofrontalis muscle b. posterior auricular branch of
c. masseter muscle fasial nerve
d. none of the above c. occipital nerve
 

d. A and B b. internal juglar vein


c. anterior fascial vein
19. all of the following are sensory d. posterior fascial vein
supply to the preauricular area of
the scalp except:-
a. auriclo temporal nerve 24. the only tributary of the
b. zygomatico temporal nerve subclavian vein is:-
c. great auricular nerve a. external nasal vein
d. supra orbital nerve b. external juglar vein
c. occipital vein
d. common fascial vein
20. all of the following are branches
from cervical spinal nerves
except:- 25. lymphatic drainage of
a. supra orbital nerve preauricular part of the scalp:-
b. lesser occipital nerve a. parotid L.N
c. great auricular nerve b. mastoid L.N
d. none of the above c. occipital L.N
d. submental L.N

21. occipitofrontalis muscle:-


a. has frontal and occipital bellies 26. the orbicularis oculi muscle is
b. supplied by branches of fascial formed of :-
nerve a. orbital part
c. move the scalp forward and b. palpebral part
backward c. lacrimal part
d. all of the above d. all of the above

22. the occipital vein ends in:- 27. which of the following musles is
a. internal juglar vein pierced by:-
b. external juglar vein a. buccinator muscle
c. suboccipital venous plexus b. orbicularis oris muscle
d. subclavian vein c. frontalis muscle
d. mentalis muscle

23. superficial temporal vein unites


with the maxillary vein forming:- 28. the middle fibers of the buccinator
a. external juglar vein muscle is inserted into:-
 

a. upper lip b. zygomatico facial


b. lower lip c. infraorbital
c. a and b d. external nasal
d. none of the above

34. the upper eyelid is supplied by the


29. the motor supply of the face is following nerves except:-
carried by: a. supratrochlear nerve
a. trigeminal lerve b. supra orbital nerve
b. facial nerve c. palpebral branch of lacrimal
c. vagus nerve nerve
d. maxillary nerve d. palpebral branch of infra orbital
nerve
30. all of the following are branches
of the facial nerve except:- 35. the buccal nerve is abranch
a. temporal nerve from:-
b. mandibular nerve a. opthalmic nerve
c. buccal nerve b. mandibular nerve
d. maxillary nerve c. maxillary nerve
d. facial nerve
31. the platysma muscle is supplied by
which branch of the facial nerve:- 36. all of the following are branches
a. cervical branch of the facial artery except:-
b. buccal branch a. superior labial
c. temporal branch b. inferior labial
d. zygomatic branch c. angular
d. mental
32. all the face is is sensory supplied
by the trigeminal nerve except:- 37. the transverse facial artery is
a. the upper lip abranch from:-
b. the lower lip a. facial artery
c. the area over the angle of the b. occipital artery
mandible c. superficial temporal artery
d. the mental area d. internal carotid artery

33. the maxillary nerve gives the 38. the common facial vein ends in
following branch except:- a. internal juglar vein
a. zygomaticotemporal b. external juglar vein
 

c. subclavian vein b. splenius capitus


d. maxillary vein c. levator scabulae
d. omohyoid muscle

39. the lymph drainage of the medial 44. all of the following pierce the
part of the face is into investing layer of the deep fascia
a. submental L.N except:-
b. submandibular L.N a. external juglar vein
c. parotid L.N b. L.V
d. mastoid L.N c. internal juglar vein
d. supraclavicular nerve
40. the side of the neck is divided into
anterior and posterior triangles 45. the posterior triangle contain the
by:- following nerves except:-
a. platysma muscle a. spinal part of accessory nerve
b. sternomastiod muscle b. glossopharyngeal nerve
c. trapezius muscle c. roots and trunks of brachial
d. levator scabulae plexus
d. cutaneous branches of cervical
41. the posterior border of the plexus
posterior triangle is:
a. sternomastoid muscle 46. all of the following are cutaneous
b. scalenius muscle branches of the cervical plexus
c. trapezius muscle except:-
d. clavicle a. great occipital nerve
b. great auricular nerve
42. the following muscle is a part of c. lesser occipital
the roof of posterior triangle d. transverse cervical
muscle:-
a. platysma muscle 47. the nerve running paralel to rhe
b. omohyoid muscle sternomastoid muscle is:-
c. splenius capitus muscle a. great auricular nerve
d. trapezius muscle b. supra cavicular nerve
c. transverse cervical nerve
43. the following muscles form the d. lesser occipital nerve
floor of the posterior triangle
except:- 48. the supra scapular artery is a
a. semispinalis capitis branch from:-
 

a. common carotid artery d. Carotid triangle and digastrics


b. facial artery triangle
c. subclavian artery
d. transverse cervical artery
53. All of the following are contents of
carotid triangle except :
49. the supra scapular vein end in:-
a. internal juglar vein a. External carotid artery
b. external juglar vein b. Carotid sheath
c. subclavian vein c. Superficial cervical lymph nodes
d. none of the above d. Sympathetic trunk

50. All of the following are the


54. Ansa cervicalis supply all the
boundries of anterior triangle of
following except :
the neck except :
a. Sternohyoid muscle
a. Mid line of the neck
b. Sternothyroid muscle
b. Inferior border of the maxilla
c. Thyrohyoid muscle
c. Inferior border of the mandible
d. Infrahyoid muscle
d. Anterior border of the
steromastoid
55. A salivary gland can be seen in
which of the following :
51. A structure is found in both
a. Digastric triangle
digastric and submental triangle :
b. Submental triangle
a. Omohyoid muscle
c. Carotid triangle
b. Hypoglossus
d. Muscular triangle
c. Sternihyoid muscle
d. Mylohyoid muscle
56. All of the following are found in
pairs except :
52. Superior bellies of omohyoid
a. Submental triangle
muscle is a common boundry of :
b. Diagastric triangle
a. Digastric and submental triangle
c. Carotid triangle
b. Digastric and muscular triangle
d. Muscular triangle
c. Muscular triangle and carotid
triangle
57. All of the following muscles are
attached to hyoid bone except :
 

a. Sternomastoid muscle b. false


b. Anterior bellies of Digastric
muscles 62. Ansa cervicalis nerve supplies all
the following muscles except:
c. Superior bellies of omohyoid
a. sternohyoid
muscles
b. sternothyroid
d. Posterior bellies of Digastric c. thyrohyoid
muscles d. superior belly of omohyoid

58. The base of the submental triangle 63. The inferior root of ansa cervicalis
nerve arises from:
is :
a. c1
a. Thyroid cartilage
b. c5
b. Maxilla
c. c3
c. Hyoid bone d. c2 &c3
d. Mandible
64. Nerve to thyrohyoid arise from :
59. All of the following can be a. c2
b. c1
considered a part of the neck
c. c3
triangles except :
d. none of the above
a. Scalenus medias
b. Scalenus anterior
65. Hypoglossus and thyrohyoid form
c. Splenius capitis the floor of muscular triangle:
d. Semispinalis capitis a. true
b. false
60. All of the following are boundaries
of the carotid triangle except: 66. Inferior belly of omohyoid is one
a. anterior border of sternomastoi of carotid triangle boundaries:
b. anterior belly of digastric muscle a. true
c. superior belly of omohyoid b. false
d. posterior belly of digastric muscle
67. The floor of carotid triangle is
61. sympathetic trunk is one of the formed by:
carotid triangle contents: a. hypoglossus
a. true b. thyrohyoid
 

c. middle and inferior constrictors of b. auricular to the skin of the


the pharynx external auditory meatus
d. all of the above c. pharyngeal
d. tympanic branch forming lesser
68. Vagus nerve is one of the carotid superficial petrosal nerve
sheath contents:
a. true 74. Descends in the neck within the
b. false carotid sheath :
a. glossopharyngeal nerve
69. All of the following are contents of b. vagus
the carotid sheath except: c. accessory
a. common carotid artery d. all of the above
b. vagus nerve
c. internal jugular vein 75. The cervical part of accessory
d. external carotid artery nerve arises from medulla
oblongata:
70. superior belly of omohyoid is one a. true
of the muscular triangle b. false
boundaries:
a. true 76. Hypoglossal nerve is a pure motor
b. false nerve:
a. true
71. sternohyoid is one of the muscles b. False
forming the deep layer of
infrahyoid muscles : 77. The terminal destination of the
a. true lymph drainage in the face and
b. false neck is the junction between
subclavian vein and ……
72. Ninth cranial nerve is :
a. Internal jugular vien
a. glossopharyngeal
b. External jugular vein
b. vagus
c. accessory c. Anterior facial vein
d. none of the above d. Retromandibular vein

73. All of the following are branches 78. The jugular trunk in the right side
of the vagus nerve except:
drains into :
a. meningeal
a. Internal jugular vien
 

b. Right lymphatic duct 86. Upper deep cervical lymph nodes


c. Thoracic duct can extend beyond the
d. Subclavian vein sternomastoid muscle

79. Which of the following ducts is 87. Posterior region of the scalp is
related to the brachial plexus : drained to :
a. Tubal tonsil a. Occipital lymph node
b. Upper deep cervical lymph node b. Postauricular lymph node
c. Lower deep cervical lymph nodes c. Parotid lymph node
d. Lingual tonsil d. Submadibular lymph node

80. Which of the following is one of 88. Mastoid nodes receives afferent
the tributaries of the jugulo from all of the following except :
omohyoid lymph nodes : a. Floor of the meatus
a. Back of the tongue b. Auricle
b. Tonsils c. Angle of jaw skin
c. Lower part of the pharynx d. Upper part of parotid region
d. Upper part of the pharynx
89. Parotid lymph nodes efferent is :
True and false :
a. Sub mandibular lymph node
81. Jugulo digastrics lymph nodes lie b. Sub mental lymph nodes
behind the internal jugular vein c. Jugulo digastrics node
82. Jugulo omohyoid lymph nodes lie d. Jugulo omohyoid node
behind the intermediate tendon of
omohyiod 90. All of the following drains to the
83. Thyroid gland drains directly to submandibular node except :
the jugular trunk a. Parotid nodes
84. Adenoid is one of the transverse b. Submental nodes
superficial lymph nodes c. Postauricular nodes
85. Deep cervical lymph nodes lie d. Upper part of the anterior
superficial to sternomastoid triangle of the neck
muscle
True and false :
 

91. Nasopharynx can drain directly to 99. All of the following can drain to
the deep lymph nodes the upper deep cervical lymph
92. Atlanto occipital joint drains to the node except :
paratracheal lymph nodes a. Occipital lymph nodes
93. Cervical part of the trachea is b. Floor of the mouth
drained to the paratracheal lymph c. Parotid of the mouth
nodes d. Mastoid lymph nodes
94. Postauricular lymph nodes lie
deep to the mastoid 100. All of the following are
95. Submental lymph nodes are considered transverse lymph
contents of the submental triangle nodes except :
of the neck a. Lower deep lymph nodes
96. Lateral column of the superficial b. Lingual tonsils
lymph nodes lies on internal c. Occipital nodes
jugular vien d. Periauricular lymph nodes

97. All of the following drain to the 101. Middle ear drains to :
submandibular nodes except : a. Mastoid lymph nodes
a. Anterior part of nasal cavityw b. Periauricular lymph nodes
b. Tip of the tongue c. Submandibular lymph nodes
c. Centre of the tongue d. Sbmental lymph nodes
d. Vessels of the gum
102. Platysma Muscle is supplied by
98. Above the vocal cord in the larynx :
drains to : a. Temporal branch of facial nerve
a. Upper deep cervical lymph b. Zygomatic branch of the facial
nodes nerve
b. Lower deep cervical lymph c. Mandibular branch of the facial
nodes nerve
c. Submandibular lymph nodes d. Cervical branch of the facial
d. Submental lymph nodes nerve
 

103. Great auricular nerve is a 107. Which of the following lymph


branch from : nodes is the site of drainage of the
a. Facial nerve scalp and lies in the posterior
b. Cervical plexus triangle of the neck?
c. Brachial plexus a. Mastoid lymph node
d. Accessory nerve b. Occipital lymph node
c. Supraclavicular lymph node
104. The foramena through which d. Parotid lymph node
cavernous sinuses can be
connected to the anterior facial 108. The site of meeting between
vein : free and attached margin of the
a. Foramen Lacerum tentorium cerebelli :
b. Foramen Ovale a. All petrous part of temporal
c. Foramen rotundum bone
d. Both a and b b. Petrous apex
e. Both b and c c. Petrous base
f. All of the above d. Anterior clinoid process

105. All of the following can end to 109. Which of the following
the confluence of sinuses except : muscles insert on the skin of eye
a. Superior sagittal sinuses borrows
b. Inferior sagittal sinuses a. Palpepral part of Orbicularis
c. Straight sinuses oculi
d. None of the above b. Frontalis
c. Orbital part of Orbicularis oculi
106. Which of the following is the d. Lacrimal part of Orbicularis
most superficial muscle : oculi
a. Semi spinalis capitis e. Both a and b
b. Splenius capitis f. Both b and c
c. Scalenus medias g. Both a , c and d
d. Levator Scapulae h. All of the above
 

110. Which of the following sinuses a. Plane synovial joint


has meningeal branches? b. Fibro cartilage
a. Occipital sinuses c. Pivot joint
b. Transverse sinuses d. Ellipsoid joint
c. Sigmoid sinuses
d. Cvernous sinuses 115. Which of the following
vertebrae is more related to the
111. The medial branch of the vertebral artery ?
external carotid artery is : a. Atlas
a. Superior thyroid artery b. Axis
b. Ascending pharyngeal artery c. 3rd cervical vertebrae
c. Facial artery d. 7th cervical vertebrae
d. Lingual artery
116. Whaldyer's ring is considered :
112. Which of the following nerves a. Deep vertical lymph nodes
has a secremotor branch to the b. Deep transverse lymph nodes
patotid salivary gland : c. Superficial transverse lymph
a. Glossopharyngeal nerve nodes
b. Vagus nerve d. Superficial vertical lymph
c. Accessory nerve nodes
d. Hypoglossal nerve
117. All of the following ligaments
113. Which of the following gives are related to the odntoid bone in
motor supply to the laryngeal axis except:
mucosa above vocal cords? a. Apical ligament
a. Recurrent laryngeal nerve b. Alar ligament
b. Pharyngeal branch of the vagus c. Cruciform ligament
nerve d. Ligamentum nuchae
c. External laryngeal nerve
d. Internal laryngeal nerve 118. One of the following lies in the
pathway of the drainage of the
114. The type of Zygapo physeal lower part of parotid region :
joint is : a. Occipital lymph nodes
 

b. Upper deep lymph nodes


c. Parotid lymph nodes
d. Sub mandibular group of
lymph nodes

119. One of the following drain to


the submandibular lymph node :
a. Sides of the tongue
b. Centre of the tongue
c. Lateral sides of the tongue
d. Soft palate

120. Which of the following arches


have branches through the
accessory nerve :
a. 3rd
b. 4th
c. 6th
d. All of the above
 

Answers: 29. B
30. D
1. D
31. A
2. C
32. C
3. A
33. D
4. B
34. D
5. D
35. D
6. C
36. D
7. A
37. C
8. B
38. A
9. C
39. A
10. A
40. B
11. C
41. C
12. C
42. A
13. B
43. D
14. D
44. C
15. A
45. B
16. C
46. A
17. B
47. D
18. D
48. C
19. C
49. B
20. A
50. B
21. D
51. D
22. C
52. C
23. D
53. C
24. B
54. C
25. A
55. A
26. D
56. A
27. A
57. A
28. C
58. C
 

59. B 89. A
60. B 90. C
61. A 91. T
62. C 92. F
63. D 93. T
64. B 94. F
65. B 95. T
66. B 96. F
67. D 97. C
68. A 98. A
69. D 99. A
70. A 100. A
71. B 101. B
72. A 102. D
73. D 103. B
74. B 104. D
75. B 105. B
76. A 106. A
77. A 107. B
78. B 108. B
79. C 109. F
80. C 110. A
81. F 111. B
82. F 112. A
83. F 113. A
84. F 114. A
85. F 115. A
86. T 116. B
87. A 117. D
88. D 118. B
 

119. A
120. D
 

II. Neuroanatomy: 5. Posteromediate septum is present


in all spinal cord in all of these

1. The length of the spinal cord is regions except :

about : a. All thoracic vertebrae

a. 10 cm b. All cervical vertebrae

b. 20 cm c. All lumber vertebrae

c. 30 cm d. All sacral vertebrae

d. 45 cm
6. All of the following can be found

2. The cervical enlargement clearly in the gray matter except :

corresponds to : a. Blood capillaries

a. Lumber plexus b. Neuroglia

b. Brachial plexus c. Myelinated nerve fibres

c. Sacral plexus d. Nerve soma

d. Cervical plexus
7. Median group in anterior grey

3. The period in which the spinal matter is present in all of the

cord occupy all the vertebral canal following except

is : a. T1

a. 1st month b. T2

b. 1st two months c. L5

c. 1st three months d. L4

d. 1st four months


8. Lumberosacral nucleus in central

4. Meningies surrounding the spinal group is present in :

cord end at the level of : a. C1

a. S1 b. C2

b. S2 c. S1

c. S3 d. C7

d. S4
9. Spinal Accessory nerve nuclei are
present in which position:
a. Medial
 

b. Lateral a. Craniosacral outflow


c. Central b. Thoracolumber flow
d. Posterior c. Thoracosacral flow
d. Lumbrosecral flow
10. Lateral group of anterior gray
matter can't be found in : 15. Anterior spinal artery arises from
a. Thoracic a. Basilar artery
b. Lumber b. Subclavian artery
c. Cervical c. Vertebral arteries
d. Sacral d. Aorta

11. Dorsal funicular group is absent 16. Which of the following where
from all of the following xcept : longitudinal branches of posterior
a. Cervical vertebrae spinal aretery branches :
b. Thoracic vertebrae a. Ventral root
c. Lumbar vertebrae b. Dorsal root
d. None of the above c. Gray matter
d. White matter
12. One of the following can be found
in the C8 vertebrae spinal cord : 17. Radicularis magna supply origin
a. Ventromedial group of
b. Dorsomedial group a. Cervical plexus
c. Both of the above b. Pharyngeal plexus
d. Central group c. Brachial plexus
d. Lumber plexus
13. T1 has all of the following except :
a. Visceral gray 18. Anterior spinal vein passes
b. Medial group through :
c. Lateral group a. Anteromedian sulcus
d. Nucleus dorsalis b. Posteromedian septum
c. Ventral root
14. Interomediolateral is concerened d. Dorsal root
with
 

19. Internal venous plexus lies inside : 24. Which of the following form the
a. Dura mattar pyramid ?
b. Extra dural space a. Corticospinal nuclei
c. Periosteum b. Inferior olivary nuclei
d. Tubular sheath c. Corticospinal fibres
d. Cuneate nuclei
20. Lumber cistern is found in :
a. Subarachnoid space 25. All of the following pass through
b. Pia matar the posterolateral sulcus except :
c. Dura matar a. Hypoglossal nerve
d. Arachnoid matar b. Glossopharyngeal nerve
c. Vagus nerve
21. Linea splinders lies in : d. Cranial accessory nerve
a. Dorsal root
b. Ventral root 26. The groove found in the pontine
c. Anteromedian sulcus transwerse fibres is for
d. Posteromedial septum a. Basilar artery
b. Basal vein
22. Last process of ligamneta c. Vertebral artery
denticulata is attached to d. Superior cerebellar artery
a. L1
b. L2 27. Which of the following nerves exit
c. L3 through the junction between
d. L4 pons and pyramid :
a. Trigeminal nerve
23. Posteromedian sulcus in the b. Abducent nerve
medulla oblongata continues as : c. Facial nerve
a. Intermediate sulcus d. Vestibualr nerve
b. Anteriomedian fissure
c. Posteromedian septum 28. Cereberal penduncle is formed of
d. Dorsal root all except :
a. Crus cerebri
b. Substantia nigra
 

c. Tegmentum 34. Basal vein crosses the cerebral


d. Tectum peduncle
35. Substania nigra is a layer of
29. Colliculi are separated by : white matter
a. Cruiciform sulcus 36. Hypoglossal trigone is the most
b. Posteromediaum sulcus lateral part of inferior floor of the
c. Anetromedian sulcus 4th ventricle
d. Intermediate sulcus 37. Groove between pyramid and olive
is called is posterolateral sulcus
30. Corpora quadrigemina is :
a. Cruiciform sulcus 38. The roof of the anterior horn of
b. Colliculi the lateral ventricle is :
c. Frenulum velli a. Anterior part of body of corpus
d. Brachium callosum
b. Genu of corpus callosum
31. Superior coliculi is associated with c. Head of caudate Nucleus
: d. Rostrum
a. Inferior brachium
b. Lateral geniculate 39. The medial wall of the body of
c. Frenulum villum lateral ventricle posteriorly is :
d. Medial geniculate a. Septum Pellucidum
b. Head of caudate nucleus
32. All of the following enters in the c. Fornix
dorsal surface of the pons except : d. Tapetum
a. Lateral vestibular nucleus
b. Medial vestibular nucleus 40. Floor of the posterior horn of the
c. Facial nerve lateral ventricle is formed by :
d. Abducent nerve a. Forceps
b. Calcarivis
c. Tapetum
True and False
d. Rostrum
33. Trigeminal nerve has large medial
sensory root
 

41. Which of the following lies in both 45. Which of the following is the
floor and lateral wall of the cavity of Diencephalon ?
anterior horn of lateral ventricle: a. Lateral ventricle
a. Tail of cauduate nucleus b. Third ventricle
b. Rosterum c. 4th ventricle
c. Septum pellucidum d. All of the above
d. Head of cauduate nucleus
46. All of the following are situated in
42. Which of the following is most the anterior wall of the third
medial in the floor of body of ventricle except :
lateral ventricle: a. Anterior commisure
a. Striathalamic vein b. Anterior column of the fornix
b. Stria terminalis c. Lamina terminalis
c. Body of fornix d. Habenular commisure
d. Chroid plexus
47. Lateral ventricle is connected to
43. Which part of the caudate nucleus the 3rd ventricle by
can be found in the inferior horn a. Interventricular foramen of
of Lateral ventricle: Monoro
a. Body b. Aqueduct of sylvius
b. Head c. Optic recess
c. Tail d. Pineal recess
d. All of the above
48. The upper lateral wall of the 4th
44. Amygloid nucleus lies in the roof ventricle is formed of :
of : a. Superior cerebellar peduncle
a. Anterior horn of lateral b. Inferior cerebellar peduncle
ventricle c. Cuneate
b. Body of lateral ventricle d. Gracile
c. Inferior horn of lateral
ventricle 49. The cerebellum occupy the middle
d. Posterior horn of lateral part of the roof of:
ventricle a. 3rd ventricle
 

b. 4th ventricle 53. The body of Caudate nucleus is


c. Body of lateral ventricle related to:
d. All of the above
a. Floor & lateral wall of inferior
horn of lateral ventricle
50. All of the following can contribute
b. Floor of central part of lateral
to the increase in CSF pressure
ventricle
except :
a. Straining c. Roof of inferior horn of lateral
b. Cough ventricle

c. Relaxation of the internal d. Lentiform nucleus


jugular vein
54. The tail of Caudate nucleus is
d. None of the above
related to:
51. Caudate nucleus formed of:
a. Floor & lateral wall of inferior
a. Head , body , lateral wall , horn of lateral ventricle
medial wall
b. Floor of central part of lateral
b. Head, lateral wall , medial wall ventricle
, tail
c. Roof of inferior horn of lateral
c. Head , body, tail ventricle

d. None of the above d. Lentiform nucleus

52. The head of Caudate nucleus is 55. The anteroinferior part of Caudate
related to: nucleus is related to:

a. Floor & lateral wall of anterior a. Floor & lateral wall of inferior
horn of lateral ventricle horn of lateral ventricle

b. Floor of central part of lateral b. Floor of central part of lateral


ventricle ventricle

c. Roof of inferior horn of lateral c. Roof of inferior horn of lateral


ventricle ventricle

d. Lentiform nucleus d. Lentiform nucleus


 

56. Corpus striatum are: b. Basolateral & Central

a. Caudate & Claustrum c. Internal capsule & external


capsule
b. Caudate & Lentiform
d. Putamen & Globus pallidas
c. Caudate & Amygdaloid
61. The medial relation of The
d. Caudate & corpus callosum
Lentiform nucleus:
57. Corpus striatum is:
a. Internal capsule
a. Blank
b. External capsule
b. White
c. Corona radiata
c. Striated
d. Anterior comissure
d. All of the above
62. The lateral relation of The
58. The Lentiform nucleus is: Lentiform nucleus:

a. Biconvex lens like a. Internal capsule

b. Biconcave lens like b. External capsule

c. Unicovex lens like c. Corona radiata

d. Uniconcave lens like d. Anterior comissure

59. The Lentiform nucleus is divided 63. The inferior relation of The
by: Lentiform nucleus:

a. Medial medullary lamina a. Internal capsule

b. Medial pallidal segment b. External capsule

c. Lateral medullary lamina c. Corona radiata

d. Lateral pallidal segment d. Anterior comissure

60. The subdivision of The Lentiform 64. The anterior relation of The
nucleus are: Lentiform nucleus:

a. Corticomedial & Basolateral a. Internal capsule


 

b. External capsule c. Above tip of anterior horn of


lateral ventricle
c. Corona radiata
d. Below tip of anterior horn of
d. Anterior comissure
lateral ventricle
65. The superior relation of The
69. Corticomedial group of
Lentiform nucleus:
Amygdaloid is connected with:
a. Internal capsule
a. Motor Nuclei of brain stem
b. External capsule
b. Sensory Nuclei of brain stem
c. Corona radiata
c. Olfactory structures
d. Anterior comissure
d. All of the above
66. Clastrum is located between:
e. Both A & B
a. Caudate & Lentiform
70. Central group of Amygdaloid is
b. Lentiform & amygdaloidal connected with:

c. Lentiform & insula a. Motor Nuclei of brain stem

d. None of the above b. Sensory Nuclei of brain stem

67. Clastrum is separated from c. Olfactory structures


Lentiform by:
d. All of the above
a. Internal capsule
e. Both A & B
b. External capsule
71. One of the following lies in the
c. Cerebral cortex anterior limb of the internal

d. Internal pallidal segment capsule :


a. Anterior thalamic radiation
68. Amygdaloid is located:
b. Posterior thalamic
a. Above tip of inferior horn of radiation
lateral ventricle c. Superior thalamic
radiation
b. Below tip of inferior horn of
lateral ventricle d. Inferior thalamic radiation
 

72. Where can occipitopontine fibres d. Retro lentiform part of


be found : posterior limb
a. Anterior limb of internal
capsule 76. Which of the following is
b. Genu of the internal capsule concerned with connection
c. Thalamolentiform part of between two different sides in the
posterior limb cortex :
d. Retrolentiform part of a. Commissural fibres
posterior limb of internal b. Association fibres
capsule c. Projection fibres
d. All of the above
73. How internal capsule is related to
the lentiform nucleus ? 77. Long association fibres lying in the
a. Medially medial surface is :
b. Superiorly a. Uncinate fibres
c. Laterally b. Cingulum
d. Inferioirly c. Superior longitudinal
fasciculus
74. Blood supply of the genu is : d. Fronto occipital fasciculus
a. Anterior cerebral artery
b. Posterior cerebral artery 78. The lateral boundary of corona
c. Internal carotid artery radiata is :
d. None of the above a. Uncinate fibres
b. Cingulum
75. All of the following receive two c. Fronto occipital fasiculus
arterial blood supplies except : d. Superior Longitudinal
a. Anterimedial part of the fasiculus
anterior limb of internal
capsule 79. The long association fibre
b. Genu of the internal capsule connecting between occipital lobe
c. Thalamolentifrom part of and temporal lobe is :
posterior limb a. Superior longitudinal
fasiculus
 

b. Inferior longitudinal fasiculus 84. All of the following are connected


c. Fronto occipital fasiculus by the anterior commissure except
d. Cingulum :
a. Olfactory bulb
80. Which of the following are b. Amygdaloid body
associated with orbital surface of c. Posterior perforated body
the frontal lobe? d. Pyriform body
a. Cingulum
b. Rostrum of corporus callosum 85. special visceral efferent fibers
c. Both secremotor supply to:
d. Non of the above a. muscles of somites
b. muscles of branchial arches
c. smooth muscles
81. Forceps minor radiates from :
d. exocrine glands
a. Rostrum
b. Genu 86. taste and olfaction sensation is
c. Body carries by:
d. Splenium a. G.V.E
b. G.V.A
c. S.V.A
82. Splenium of the copus callosum
d. S.S.A
radiate fibres related to :
a. Posterior horn of lateral 87. the following nuclei are presented
ventricle in the midbrain except:
b. Anterior horn of lateral a. oculomotor nucleus
ventricle b. edinger westphal nucleus
c. trochlear nucleus
c. 3rd ventricle
d. facial nucleus
d. 4th ventricle

88. nucleus ambiguous is found in:


83. Which of the following is most a. medulla oblongata
superior ? b. midbrain
a. Cerebral aqueduct c. pons
b. Posterior commissure d. spinal cord

c. Habenular commissure
d. None of the above
 

89. the lateral rectus muscle of the eye b. occipitofrontalis muscle


is supplied from: c. stylopharyngeal muscle
a. oculomotor nucleus d. stylohyoid
b. abducent nucleus
c. trochlear nucleus 95. the fibers forming the cranial
d. hypoglossal nucleus outflow of the parathympathatic
nervous system:
90. the trochlear nucleus supplies: a. G.S.E
a. lateral rectus muscle b. S.V.E
b. superipr oblique muscle c. G.V.E
c. palatoglossus muscle d. G.V.A
d. none of the above
96. the parathympathatic part of the
91. the motor nucleus of trigeminal occulomotor nerve is:
nerve supplies all of the following a. superior salivary nucleus
except: b. inferior salivary nucleus
a. anterior belly of digastrics c. solitary nucleus
b. mylohyoid d. edinger westiphal nucleus
c. stylohyoid
d. tensor tympani 97. inferior salivary nucleus gives
preganglionic fibers to:
92. nucleus ambiguous gives fibers to a. lacrimal glands
the following nerve: b. parotid gland
a. accessory nerve c. submandibular gland
b. facial nerve d. buccal gland
c. trigeminal nerve
d. hypoglossal nerve 98. the following nucleus gives rise to
general visceral efferent fibers:
93. the only muscle derived from the a. edinger westphal nucleus
third branchial arch is: b. superior salivary nucleus
a. tensor palate c. inferior salivary nucleus
b. mylohyoid d. all of the above
c. platysma
d. stylopharyngreus 99. which of the following nuclei
receive visceral afferent fibers:
94. the facial nucleus supplies the a. solitary nucleus
following muscles except: b. olivary nucleus
a. muscles of the face c. hypoglossal nucleus
 

d. none of the above 105. the nucleus responsible for


receiving pain and temperature
100. solitary nucleus receive from the head is:
general sensory fibers running in: a. spinal nucleus of trigeminal
a. vagus nerve b. main sensory nucleus
b. glossopharyngeal nerve c. superior salivary nucleus
c. trigeminal nerve d. mesencephalic nucleus
d. both a and b
106. S.S.A include the following
101. sensation from the respiratory except:
tract, abdominal viscera and GIT a. vestibular nucleus
are received by: b. cochlear nucleus
a. facial nucleus c. solitary nucleus
b. superior salivary nucleus d. all of the above
c. solitary nucleus
d. trochlear nucleus 107. the cerebellum is the posterior
part of the midbrain
102. taste sensation is carried by the a. True
following except: b. False
a. facial nerve
b. glossopharyngeal nerve 108. The cerebellum lies in the
c. vagus nerve ………. Cranial fossa
d. trigeminal nerve a. Anterior
b. Posterior
103. cardiorespiratory nucleus c. Inferior
mediates reflex control of: d. Superior
a. cardiovascular system
b. respiratory system 109. The pons and medulla are
c. gastrointestinal system separated from the cerebellum
d. all of the above anteriorly by the
a. Lateral ventricle
104. which of the following is not a b. Third ventricle
sensory trigeminal nucleus: c. Fourth ventricle
a. mesencephalic nucleus
d. All of the above
b. solitary nucleus
c. main sensory nucleus
d. none of tne above
 

110. ……….. covers superiorly the 115. …………. Separates the


cerebellum and separates it from anterior lope from the posterior
cerebrum lobe of cerebellum
a. Falx cerebelli a. Fissure prima
b. Falx cerebri b. Horizontal fissure
c. Tentorium cerebelli c. Postpyramidal fissure
d. None of the above d. Retrotonsillar fissure

111. …………. Is the most anterior 116. …………. Is the fissure that
part of the superior vermis separates the nodule from the
a. Nodule uvula in the cerebellum
b. Uvula a. Fissure prima
c. Pyramid b. Horizontal fissure
d. Lingula c. Posterolateral fissure
d. Retrotonsillar fissure
112. The inferior medullary velum
forms the bed of ………. In 117. all of the following are found
cerebellum in inferior surface of cerebellum
a. Tube vermis except
b. Vermis a. Fissura secunda
c. Cerebellar tonsil b. V- shaped fissure
d. Medullary vella c. Retrotosillar
d. Posterolateral fissures
113. superior medullary vella is a
thin sheet of white matter forming 118. The components of the
the tonsillar bed diencephalon are all except :
a. True a. thalamus
b. False b. hypothalamus
c. stria habenularis
114. the cerebellum shows a wide U
shape anterior notch that lodges
119. The lateral boundary of the
the falx cerebelli
thalamus is the:
a. True
a. the posterior limb of the
b. False internal capsule
b. the cavity of the third ventricle
c. the lentiform nucleus
 

120. The superior relations to the 125. The anterior thalamic


thalamus are radiation connects the anterior
a. the body of lateral ventricle and medial nuclei with the
b. the thalamostriate vein a. frontal lobe
c. the choroid plexus b. parietal lobe
d. all of the above c. occipital lobe

121. The inferior relations are 126. The superior thalamic


including all of the following radiation connects the lateral and
except the ventral nuclei with the
a. tegmentum of the midbrain a. temporal lobe
b. the hypothalamus b. the parietal lobe
c. fornix c. pre and post central gyri

122. The superior white matter of 127. The blood supply of the
the thalamus is called : thalamus is the
a. external medullary lamina a. posterior cerebral artery
b. stratum zonale b. anterior cerebral artery
c. internal medullary lamina c. basilar artery
d. a and c
123. The lateral part of the
thalamus lying lateral to the
128. Epithalamus consists of all of
internal medullary stria is
the following except :
subdivided into
a. pineal body
a. dorsolateral part
b. habenular nuclei
b. ventromedial
c. habenular commissure
c. both
d. the choroid plexus
124. The function of the thalamus is
integration of the information 129. The medial geniculate body is
from the a relay nucleus in the

a. cerebellum a. pathway of hearing

b. basal ganglia b. pathway of vision

c. reticular formation of the c. pathway of smelling

brain stem
d. all of the above
 

130. The metathalamus consists of


the
a. medial geniculate body
b. lateral geniculate body
c. both
 

Answers: 32. B
33. T
1. D 34. T
2. B 35. F
3. C 36. F
4. B 37. F
5. C 38. A
6. C 39. C
7. C 40. B
8. C 41. D
9. C 42. C
10. A 43. C
11. D 44. C
12. A 45. B
13. C 46. D
14. B 47. A
15. C 48. A
16. B 49. B
17. D 50. C
18. A 51. C
19. B 52. A
20. A 53. B
21. C 54. C
22. A 55. D
23. C 56. B
24. C 57. C
25. A 58. A
26. A 59. C
27. B 60. D
28. D 61. A
29. A 62. B
30. B 63. D
31. B 64. C
 

65. C 98. D
66. C 99. A
67. B 100. D
68. A 101. C
69. C 102. D
70. E 103. D
71. A 104. B
72. D 105. A
73. A 106. C
74. C 107. B
75. C 108. B
76. A 109. C
77. B 110. C
78. D 111. D
79. B 112. C
80. B 113. B
81. B 114. B
82. A 115. A
83. C 116. C
84. C 117. B
85. B 118. C
86. C 119. A
87. D 120. D
88. A 121. C
89. B 122. B
90. B 123. C
91. C 124. D
92. A 125. A
93. D 126. C
94. C 127. D
95. C 128. D
96. D 129. A
97. B 130. C
 

Pharmacology of the CNS: 5. It’s not necessary to perform


gastric lavage in case of Morphine
poisoning due to parentral over
1. Analgesics are :
dose :
a. Drugs that relieve pain due to
a. True
multiple causes
b. False
b. Drugs that relieve pain due to
a single cause
6. All of the following centers are
c. Classified into opioid and non-
depressed by Morphine EXCEPT :
opioid analgesics
a. Cortical pain center
d. Can produce addiction
b. Respiratory center
e. A & C
c. Cough center
d. Vasomotor center
2. All opium alkaloids can be used
clinically : e. Occulomotor center
a. True
7. Morphine analgesic effect is done
b. False
through :
a. Decrease in the threshold of
3. All of the following are opioid
pain perception in the sensory
receptors on which opium
areas
alkaloids act EXCEPT :
a. Mu receptors b. Alteration in the response to
pain
b. Kappa receptors
c. Alpha receptors c. Reducing the pains effect on
the behavior
d. Sigma receptors
d. A& B
e. Delta receptors
e. B & C

4. Morphine can be absorbed by all


8. Large doses of Morphine can lead
of the following methods of
to vasodilatation due to :
administration except :
a. Release of histamine
a. Oral administration
b. Inhibition of vasomotor center
b. Topical adminstration
c. Respiratory depression which
c. Intramusclar injection
increases the level of CO2
d. Inhalation
d. All of the above
e. Subcutanous injection
e. A & B
 

9. Morphine reduces the rate and due to its respiratory


depth of respiration by : depression
a. Depression of respiration c. It’s not preferable to patient
b. Reduction of the senstivity of with the bronchial tree cancer
the respiratory center to CO2 due to its histamine release
c. Bronchoconstriction and bronchoconstriction
d. All of the above d. All of the above

e. A & B
13. Morphine indirectly stimulates the
10. An old male patient came to the Edinger-Westphal nucleus of the
hospital with cancer of bronchial oculomotor (3rd cranial nerve )
tree suffering from severe cough , and cause severe mydriasis :
the doctor took the patient’s a. True
history and figured out that he has b. False
a prostatic hypertrophy, which of
the following drugs should be 14. The indirect stimulation of the
given to the patient : Edinger-Westphal nucleus of the
a. Morphine oculomotor (3rd cranial nerve ) by
Morphine is produced by :
b. Methadone
a. Cortical inhibitory effect on
c. Codeine
the the Edinger-Westphal
d. Meperidine
nucleus of the oculomotor (3rd
cranial nerve )
11. Which of these drugs is contra-
b. Stimulation of Cortical
indicated to the previous case:
inhibitory effect on the the
a. Morphine
Edinger-Westphal nucleus of
b. Methadone
the oculomotor (3rd cranial
c. Codeine nerve )
d. Merperidine c. Inhibition of Cortical
inhibitory effect on the the
12. The reason why the doctor didn't Edinger-Westphal nucleus of
give it to the patient: the oculomotor (3rd cranial
a. It has a side effect of urine nerve )
retention more than the d. All of the above
prescribed drug
b. It’s not preferable to patient
with the bronchial tree cancer 15. One the morphine’s side effects is
constipation which is produced by
all of the following EXCEPT :
 

a. Decrease in the peristaltic e. A & C


activity and increase in
segmetation movement 19. Which of the following conditions
b. Increase in the tone of Morphine should be given with
intestinal smooth muscles atropine :
c. Spasm of biliary passages a. Renal colic
d. Spasm of sphincters b. Biliary colic
e. Decrease in the perception of c. Coronary thromposis
defecation reflex d. A & C
e. A & B
16. All of the following are caused by
Morphine as a result of histamine 20. Morphine can be used in all of the
release EXCEPT : following conditions EXCEPT :
a. Urine retention a. Certain cases of severe
b. Sweating and itching diarrhea
c. Vasodilatation b. Acute left ventricular failure
d. Bronchoconstriction c. Pre-anaethetic medication
e. Hypotention d. Relieving of severe pain in
acute abdomen
17. Urine retention is a side effect of
Morphine due to : 21. All of the following can be Minor
a. Spasm of the urinary bladder side effects of Morphine EXCEPT :
sphincter a. Nausea, vomiting and
b. Stimulation of the micturation constipation
reflex b. Hypotention
c. Decrease in urine formation c. Urine retention
due to central release of anti- d. Addiction
diuretic hormone
e. Increased intracranial tention
d. All of the above
e. A & C 22. Morphine is contra-indicated in
case of head injuries due to :
18. Tolarence to Morphine is not a. Increase levels of CO2
developed to : b. Respiratory depression
a. Respiratory depression
c. Cerebral vasodilatation
b. Constipition
d. Increase in the CSF pressure
c. Miosis
e. All of the above
d. B & C
 

c. It has a smooth muscle


23. The cause of withdrawal syptoms relaxant effect
following sudden stoppage of d. None of the above
morphine addiction is :
a. Endogenous opioid is deficient 27. Morphine and Meperdine are
b. Opioid receptors becomes free similar in :
of endogenous and exogenous a. Causing Severe Miosis effect
opioids b. Causing Cough center
c. Opioid receptors are saturated depression
by exogenous opioids c. Causing Respiratory
d. A & C depression
e. A & B d. Analgesic effect
e. Causing Histamine release
24. Morphine like compounds in the
brain are called enkephalids and 28. Meperidine is used in obstetrics to
in pituitary gland are called relive labour pain instead of
amdrophins : Morphine because :
a. True a. Morphine can cross blood-
b. False placental barrier while
Meperidine can't
b. Morphine causes respiratory
25. Methadone is used in the in the
depression in newly born
treatment of Morphine addiction
infant while Meperidine
because :
doesn’t
a. It has minor side effects
c. Both of them cross blood-
b. It’s also an addicting drug
placental barrier but
c. Its withdrawal symptoms are
Meperidine doesn’t cause
less than those of morphine
respiratory depression unlike
d. A & B
Morphine
e. B & C
d. A & B

26. Meperidine is characterized by


29. All of the following are true about
papaverine-like action because :
Naloxone EXCEPT :
a. It has a parasympatholytic
a. It’s a competitve narcotic
effect
antagonist at all opioid
b. It has an analgesic effect receptors
 

b. It has a rapid onset (1-5 c. Pentazocine is an example of


minutes) these drugs
c. It has a short duration of d. All of the above
action e. A & C
d. It can be given orally or by IM
or subcutanous injection 33. All of the following are true about
Pentazocine EXCEPT :
30. The difference between a. It’s an agonist on kappa
Naltrexone and Naloxone is that : receptors
a. Naltrexone has a longer b. It’s a weak antagonist at Mu
duration of action than receptors
Naloxone c. It’s an effective analgesic by
b. Naltrexone can be given orally itself
while Naloxone can't d. It behaves as an antagonist
c. Naltrexone has more rapid when given in combination
onset than Naloxone with Naloxone
d. A & B
e. A & C 34. NSAIDs are a group of drugs that
share in common the capacity to
31. Therapeutic uses of Opioid induce
antagonists are : a. Analgesic effect
a. Treatment of acute morphine b. Antipyretic effect
poisoning c. Anti – inflammatory effect
b. Treatment of morphine d. All of the above
addiction
c. Diagnosis of morphine
35. Any drug has analgesic antipyretic
addiction
effect classified as NSAIDs
d. All of the above
a. True
e. A & C
b. False

32. Mixed agonist-antagonist opioid


36. NSAIDs that inhibit cyclo –
analgesics are :
oxgenase enzyme centrally
a. Drugs that acts on only one
produce .......
opioid receptors
a. Analgesic effect
b. Drugs that stimulate one
b. Antipyretic effect
receptor but block another
c. Anti – inflammatory effect
 

d. Both a , b b. PGE2
c. IL-1
37. NSAIDs that produce the anti – d. All of the above
inflammatory effect inhibit cyclo –
oxgenase enzyme ..... 42. Salicylates lower the elevated body
a. Centrally temperature to normal by
b. Periphery a. Inhibiting prostaglandins
c. Both of them centrally
d. Non of the above b. Inhibiting prostaglandins
periphery
38. Non selective COX inhibitors c. Inhibiting IL-1 synthesis
associated with gastrointestinal d. Both a ,c
tract upset and renal impairment
on long term use 43. All of the following are the
a. True mechanism that salicylates use to
b. False loss heat by acting on heat
regulating center except
39. salicylates act on ......... level to a. Vasoconstriction of cutaneous
produce their analgesic action blood vessels
a. Thalamus b. Increasing sweating
b. Hypothalamus c. Encouraging evaporation
c. Subcortical d. VD of cutaneous blood vessels
d. All of the above
44. Decreasing of prostaglandins and
40. Raising of the threshold to painful inhibition of chemotaxis is the
stimuli relayed from the thalamus mechanism by which salicylates
to the sensory cortex is the way by produce
which salicylates produce a. Analgesic effect
a. Analgesic effect b. Antipyretic effect
b. Antipyretic effect c. Anti – inflammatory effect
c. Anti – inflammatory effect d. All of the above
d. Both a , b
45. NSAIDs gastritis is always due to
41. During fever .there is release of .... direct irritation of gastric mucosa
by the released salicyclic acid
a. PGE1
a. True
 

b. False a. Visual disturbances


b. Ringing in the ear
46. ........is/ are produced due to c. Confusion
prolonged use of salicylates except d. All of the above
a. Gasric ulceration
b. Peptic bleeding 51. Aspirin allergy may be manifested
c. Both of them in the form of urticaria only
d. Non of the above a. True
b. False
47. In gout patient , salicylates are
used in ........ doses 52. Salicyltes is the best choice for
a. Small treating chicken pox in children
b. Large a. True
c. Less than 5 g /day b. False
d. All of the above
53. .......... is preferred in treatment of
48. In the effect of salicylates on the influenza in children
blood .all of the following are true a. Morphine
except b. Aspirin
a. Inhibition of COX platelet c. Paracetamol
b. Reduce production of TXA2 d. All of the above
c. Increase sedimentation rate
d. Prolongation of bleeding time 54. Paracetamol shouldn’t use in
pregnancy
49. Salicylates is used in all the a. True
following cases except b. False
a. Common cold
b. Coronary thrombosis 55. Therapeutic doses of paracetamol
c. Cardiac complication of acute may lead to acute hepatic necrosis
rheumatic fever a. True
d. Toothache b. False

50. Repeated administration of large


doses of salicylates as in rheumatic
fever result in
 

56. Cardiac depression and serious 62. Lipid solubility enhances the
arrhythmia is one of the side a. onset
effects of b. duration of action
a. isoflurane c. intensity of the local anesthesia
b. sevoflurane
c. halothane 63. As the amount of the unionized
fragment increases the duration of
57. Malignant hyperthermia is a onset
genetic disease at which the a. increases
patient have taken b. decreases
a. succinylcholine c. remains constant
b. halothane
c. both 64. The onset of action is faster by
a. increasing
58. at which it is treated by b. decreasing the gap between
a. dantrolene the PKa and the PH of the
b. propofol tissue

59. Cause of the vomiting is the 65. we ought not to use a


stimulation of the sympthatomimetic with a local
a. CTZ anethetics because of the resulting
b. CIC a. vasodilatation
b. vasoconstriction
60. Relaxation of the skeletal muscles
as a side effect of the inhalational 66. which may cause local ischemia in
anesthesia is enhancing the effect the
of the a. digits
a. neuromuscular blockers b. abdomen
b. sympthatomimetics
c. sympthatolitics 67. We use cocaine topically in
a. otolaryngeal
61. Mechanism of action of all local b. nasopharyngeal use to reduce
anesthetics is by the mucosal bleeding
a. binding to the Na+ channel
from outside 68. One of the systemic side effects of
b. binding to the Na+ channel the local anesthetics is the
from inside a. convulsions
 

b. arrhythmia
c. allergy produced by the
lignocaine

69. The metabolism of the esters is


through the
a. liver
b. pseudo cholinesterase

70. The half life time of the amides is


a. longer
b. shorter than that of esters

71. The metabolism of the procaine


leads to the formation of the
a. benzoic acid
b. para amino benzoic acid

72. Allergy is more common in the


a. esters
b. amides 
 

Answers: 36. D
37. B
38. A
1. E
39. D
2. B
40. A
3. C
41. D
4. B
42. D
5. B
43. D
6. E
44. C
7. E
45. B
8. E
46. C
9. E
47. B
10. C
48. C
11. A
49. C
12. A
50. D
13. B
51. B
14. C
52. B
15. C
53. C
16. A
54. B
17. E
55. B
18. D
56. C
19. E
57. C
20. D
58. A
21. D
59. A
22. D
60. A
23. E
61. B
24. B
62. A
25. E
63. B
26. C
64. B
27. D
65. B
28. C
66. A
29. D
67. A
30. D
68. A
31. E
69. B
32. D
70. A
33. D
71. B
34. D
72. A
35. B
 

Histology of the CNS: 4. an electron dense membrane


of the target neuron at the
site of synapse.
1. When a synapse is formed
between an axon and a a. Synaptic cleft
dendritic spine then it is b. Postsynaptic membrane
called:
c. Presynaptic membrane
a. Axodendritic
b. Axosomatic 5. During anaesthesia in order to
c. Dendrodendritic avoid paralysis caused by
d. Axo-axonic injecting substances in the spinal
cord doctors prefer to inject the
2. synapses are which are
patient with the anaesthetic
commonly found in the
substance in
nervous system are
a. Below L2
a. Axodendritic and axosomatic b. In thoracic region
b. Axoaxonic and dendrodendritic c. Bet C4 & C5
c. Axodendritic and
dendrodendritic 6. The no. of cervical segments of
d. Axosomatic and axoaxonic the spinal cord is:

3. Which of the following is a. 5

incorrect about electrical b. 7

synapses: c. 6
d. 8
a. It is a gap junction
b. providing for cells electrical 7. What is the structure that is
coupling almost absent in the Gray Matter
c. Transmission of impulse is a. nerve cells
Direct and unidirectional b. myelinated nerve fibers
d. Less commonly present in the c. neuroglia
nervous system than chemical d. capillary bed
synapses
 

8. all of the following is corrct 11. Which of the following nuclei


concerning the anterior horn gives rise to the ventral
except: spinothalamic tracts?
a. broad in the cervical and a. The substantia gelatinosa of
lumbosacral segments Rolandi,
b. contains large multipolar b. The nucleus proprius
motor neurons c. The nucleus dorsalis of Clarke
c. called the motor nuclei
d. axons of these cells form the 12. Which of the following nuclei is
sensory fibers emerging in the absent in L5?
dorsal root of spinal nerves a. The substantia gelatinosa of
Rolandi,
9. the following nuclei are only b. The nucleus proprius
present in the cervical and c. The nucleus dorsalis of Clarke
lumbar enlargements.
a. antero-medial 13. All of the following statements
b. postero-medial are correct about the lateral horn
c. antero-lateral of the spinal cord except:
d. postero-lateral a. Present in all thoracic
segments
10. which of the following b. The cells are small multipolar
statements is incorrectly neurons
describing substantia gelatinosa c. belonging to the somatic
of Rolandi nervous system
a. Represented in all segments of
the spinal cord. 14. They are formed of small nerve
b. One of the anterior horn cells cells with short axons that
c. Impulses from it are carried by ascend and descend for few
the lateral spinothalamic segments on the same side.:
tracts. a. nucleus proprius
d. Important cell station for b. sympathetic nuclei
impulses of pain and c. commissural neurons
temperature d. intersegmental neurons
 

15. all of the followings statements subconscious level of the


are correctly describing coma cerebellum or midbrain:
tracts except: a. Gracile & Cuneate
a. present in the dorsal white b. Spino-tectal tract
column of the cervical c. Ventral spino-thalamic
segments. d. ventral spino-cerebellar
b. It lies between the gracile and
cuneate tracts. 19. the Olivospinal tract is absent in
c. It carries proprioceptive fibers all the following segments
to the anterior horn cells except:
d. It control the function Of the a. Cervical level
lower part of the body b. Thoracic level
through the actions of the c. Lumbar level
reflex arcs. d. Sacral level

16. One of the similarities between 20. The lateral horn cell is found in :
The Septomarginal tract and The a. Cervical level
Comma-Shaped tract is b. Thoracic level
a. Site in the spinal cord c. Lumbar level
b. Function d. All of the above
c. Side of the body it controls
21. The only tract that is absent in
17. Gracile & Cuneate tracts carry the cervical segments of the
impulses of : spinal cord is:
a. proprioceptive sensations a. Septomarginal
b. crude touch b. Olivospinal
c. pain & temperature c. Cuneate
d. simple touch d. Lateral tecto-spinal

18. One of the Tracts carrying pain 22. The central canal of the spinal
impulses, which will not reach cord is posteriorly situated at :
the cerebral cortex but end in the a. Cervical level
b. Thoracic level
 

c. Lumbar level b. It's One of the huge upper


motor neurons
d. Sacral level
c. It's of stellate type

23. The deep grooves that can be d. It's found in the motor cortex

seen in cerebrum are called:


a. Sulci 27. The stellate cells transmit motor

b. Gyri and sensory impulses from and


to the cerebrum

24. The two cerebral hemispheres a. True

are connected together by thick b. False

band of grey matter called


corpus callosum. 28. The following are examples of

a. True stellate cells except:

b. False a. Horizontal cells of Cajal


b. Fusiform cells

25. All of the following statements c. Cells of Martinotti

are correctly describing the d. Astrocytes

pyramidal cells except:


a. The apex is directed to the 29. the molecular layer is formed

cortical surface. a thick mainly of :

branching dendrite arises from a. small stellate cells

the base of the cell and passes b. neuroglia

into the underlying white c. Axons and Dendrites

matter. d. small horizontal neurons

b. Small cells are usually


superficial 30. the inner granular layer is

c. they are well developed in formed mainly of :

motor centers a. small stellate nerve cell bodies


b. neuroglia

26. Which of the following is in c. Axons and Dendrites

incorrect about Betz cells d. small horizontal neurons

a. It's The largest cells of the


cortex
 

31. The large pyramidal cells with b. It is connected with the


their long dendrites running cerebellum by means of the
towards the molecular layer are inferior cerebellar peduncles.
mainly found in : c. In the closed medulla, there
a. Molecular layer are motor decussation of the
b. The outer pyramidal cell layer cortico-spinal tracts in the
c. The pleomorphic layer upper level
d. The inner pyramidal cell layer
35. Which of the following is
32. All of the following statements incorrect about the trigeminal
are right about Martinotti cells (5th) cranial nerve nucleus
except: a. homologous to substantia
a. They are present in the The gelatinosa of Rolandi
pleomorphic layer b. carry pain and temperature
b. They are small and unipolar from the face
c. Their axons proceed towards c. starts to appear at the level of
the surface giving collaterals closed Medulla at the level of
on their way. Sensory Decussation

36. ventral cortico-spinal tract is


33. The area called the striate area as
uncrossed fibers that descend on
it appears striated by the naked
the same side as direct pyramidal
eye:
tract
a. The motor area
b. The sensory area a. true

c. The visual area b. false


d. The olfactory area

37. All the descending extra


34. All of the following statements
pyramidal tracts are present in
about the medulla oblongata are
the Closed Medulla at the level of
correct except:
Motor Decussation except:
a. It is continuous above with the
a. sulcomarginal tract
pons
b. septomarginal tract
 

c. rubrospinal tract d. Protect the brain from foreign


38. The crossed internal arcuate particles
fibers ascend on the opposite side 42. All of the following can be found
of the brain stem and continue as or related to the arachnoid
the Medial Lemniscus. except :
a. True a. CSF
b. False b. Dense fibrous connective
tissue
39. Cranial nerve nuclei of the c. Delicate tissue trabaculae
hypoglossal and of the vagus d. Thin epithelial tissue
appear in the gray matter around
the central canal at the level of 43. One of the following can be
open medulla. found in the granular layer of
a. True cerebellum :
b. False a. Axon of Purkinjie cells
b. Purkinjie cell bodies
40. ..act as relay station for the c. Granule cell bodies
proprioceptive pathway coming d. Dendrites of Pukinjie cells
from the spinal cord to the
cerebellum 44. Neuroglia is found in one of the
a. Cuneate nuclei following layers :
b. Medial Lemniscus. a. Molecular cell layer
c. lateral cuneate nuclei b. Granular cell layer
d. arcuate nuclei c. Purkinjie cell layer
d. All of the above
41. All of the following are
properties of blood brain barrier 45. All of the following synapse with
except : the dendrites of the Purkinje cells
a. Endothelium with occluding except :
junction a. Mossy fibres
b. Neuroglia can be found b. Granular cells axon
c. Gap junction can be observed c. Climbing fibres
d. Neurons of molecular layer
 

46. The most medial cerebellar 50. Which of the following nerve
nucleus is : nuclei appears in upper mid
a. Nucleus Dentate brain :
b. Nucleus Fastigii a. 3rd cranial nerve
c. Nucleus emboli b. 4th cranial nerve
d. Nucleus Globosus c. 6th cranial nerve
d. 7th cranial nerve
47. All of the following can be seen
in a section of the mid brain
except :
a. 4th ventricle
b. Cerebral aqueduct
c. Tectum
d. Cerebral peduncle

48. Middle longitudinal bundle can


be found in all of the following
except :
a. Closed medulla
b. Open medulla
c. Tectum of mid brain
d. Pons

49. The main function of inferior


colliculus is :
a. Hearing in relation to
movement
b. Vision reflex
c. Gag reflex
d. Stretch reflex
 

Answers: 31. D
32. B
33. C
1. A
34. C
2. A
35. C
3. C
36. A
4. B
37. A
5. A
38. A
6. D
39. B
7. B
40. D
8. D
41. C
9. D
42. B
10. B
43. C
11. B
44. A
12. C
45. A
13. C
46. B
14. D
47. A
15. D
48. C
16. B
49. A
17. A
50. A
18. D
19. A
20. B
21. A
22. D
23. A
24. B
25. A
26. C
27. B
28. D
29. C
30. A
 
 

Chapter 3: Special senses: b. Frontal nerve


c. Trochlear nerve

Anatomy of special d. Abducent nerve

senses:
5. All of the following openings
are found in the lateral wall of
1. All of the following are related the orbit except:
to the roof of the orbit except : a. Superior orbital fissure
a. Trochlea b. Ethmoid fissure
b. Optic nerve c. Zygomatotemporal canal
c. Infra orbital vessels d. Zygomatofacial canal
d. Lacrimal gland

6. All of the following can be


2. All of the following forms the found in the orbit except :
medial wall of the orbit except a. Vessels
: b. Muscles
a. Lacrimal bone c. Nerves
b. Ethmoid bone d. Lymph nodes
c. Body of sphenoid
d. Greater wing of sphenoid 7. All of the following are
intrinsic muscles in the eye
3. Which of the following bones ball except :
forms a part of two boundries a. Sphincter papillae
of the orbit : b. Dilator papillae
a. Zygoma c. Lateral rectus
b. Maxilla d. Ciliary body
c. Lacrimal bone
d. Ethmoid 8. One of the following has
different nerve supply from
4. Most lateral structure passing the others :
inside the superior orbital a. Superior rectus
fissure : b. Lateral rectus
a. Lacrimal nerve c. Medial rectus
 

d. Inferior rectus a. Optic nerve


b. Frontal nerve
9. If both superior and inferior c. Lacrimal nerve
rectus contract together : d. Nasociliary nerve
a. No motion occurs
b. Deviation to lateral side 14. Length of optic nerve is :
c. Deviation to medial side a. 1 cm
d. Protrusion of eye ball b. 2 cm
c. 3 cm
10. Optic nerve is the cranial d. 4 cm
nerve number :
a. 1 15. Terminal branch of the
b. 2 ophthalamic artery is
c. 3 a. Dorsal nasal
d. 4 b. Superotrochlear
c. Both
11. Optic nerve is connected to the d. None
other side by :
a. Optic chiasma 16. The sinus to which orbit is
b. Anterior perforating drained to is :
process a. Cavernous sinuses
c. Mamillary body b. Superior sagittal sinuses
d. Optic tract c. Inferior sagittal sinuses
d. Transverse sinuses
12. Zygomatic nerve is a branch of
: 17. The check ligaments extends
a. Ophthalamic nerve from :
b. Maxillary nerve a. Bulbar fascia
c. Mandibular nerve b. Optical periosteum
d. None of the above c. Optical septum
d. Suspensory ligament
13. Supratrochlear nerve is a
branch from :
 

18. The smallest and most a. True


important branch of b. False
ophthalamic artery is :
a. Lacrimal artery 23. The subcutaneous tissues of the

b. Central artery of retina cartilaginous part of The external

c. Palpebral artery acoustic meatus are rich in


seruminous glands which secrete
d. Meningeal branch
serumin
a. True
19. Lateral palpebral artery is
b. False
branched from :
a. Ophthalamic artery
24. Which of the following
b. Lacrimal artery
statements about the tympanic
c. Central artery of the retina
membrane is incorrect?
d. Dorsal nasal artery
a. When examined by autoscope
or direct light the
20. Apex of the orbit is directed :
anteroinferior part of the
a. Posteriorly
membrane appears bright
b. Anteriorly
b. Its Middle is containing
c. Laterally
chorda tympani nerve
d. Medially
c. Its inner layer is Formed of
fibrous tissue
21. The nerve supplies the skin of the
d. The outer surface of its inner
auricle near the external acoustic
layer is innervated by branch
meatus
of-vagus-nerve
a. A branch of vagus
b. Hypoglossal nerve
25. All of the following about the
c. Vestibulocochlear nerve
relations of the middle ear are
d. Glossopharyngeal-nerve
correct except:
a. The Medial wall is related to
22. In the bony part ( lateral 1/3) of
the facial canal
The external acoustic meatus
b. The anterior wall is related to
There is a constriction called
aditus to mastoid antrum
isthmus
 

c. The Floor is related to the c. It is composed of: Utricle,


tympanic branch of the Saccule , semi circular duct
glossopharyngeal nerve and tympanic membrane
d. The mastoid wall is Related to d. Formed of a sac is filled with a
facial canal viscous fluid with low Na
content
26. A branch of the vagus nerve
supplies:
a. the skin of the auricle near the
external acoustic meatus.
b. the outer surface of the
tympanic membrane
c. the inner surface of the
tympanic membrane
d. the middle ear
e. a and b
f. and c
g. all of the above
27. hyperacusis can occur In cases of
facial paralysis due to paralysis
of the tensor tympani muscle
a. true
b. false

28. Which of the following


statements about the
membranous labyrinth is
incorrect :
a. It is in the form of
membranous sac inside the
bony labyrinth
b. Outside the sac lies the
perilymph between the sac and
the bony labyrinth
 

Answers:

1. C
2. D
3. A
4. A
5. B
6. D
7. C
8. B
9. C
10. B
11. A
12. B
13. B
14. D
15. C
16. A
17. A
18. B
19. B
20. A
21. A
22. B
23. A
24. C
25. B
26. E
27. B
28. C
 
 

Histology of special d. The basal cell layer


responsible for the epithelial
senses:
regeneration

1. All of the following are contents of 5. ……………. Protects the cornea


the orbit except: from trauma or bacterial invasion
a. Eye ball a. Bowman’s membrane
b. Lacrimal glands b. Descemet’s membrane
c. Orbital lymph nodes
d. Conjunctiva 6. All of the following are true
concerning the substantia propria
2. All of the following are parts of the except:
uvea except: a. It’s the thickest layer of the
a. Choroid cornea
b. Ciliary body b. It contains 60 regular
c. Cornea lamellae of parallel collagen
d. Iris bundles that cross parallel to
each other
3. The cornea contains: c. Characterized by the presence
a. Blood vessels of the butterfly cells
b. Lymphatics d. The fibers and the cells are
c. Nerve endings embedded into the corneal
d. Muscles proteoglycans

4. All of the following are true 7. All of the following are factors
concerning the corneal epithelium contributing into the corneal
except: transparency except:
a. The basal cell layer shows a. The absences of blood vessels
microvilli embedded into the b. The equal spacing between el
percorneal tear film collagen bundles
b. It contains plenty of free c. The collagen bundles are
nerve endings oriented at right angles to
c. Sensitive to pain and touch each other
 

d. None of the above d. Venae verticosae

8. All of the following changes 11. ……………. Is responsible for


occurs at the limbus except: nutrition and blood supply of the
a. The corneal epithelium retina
becomes continuous with the a. Ciliary body
bulbar conjunctiva b. Aqueous humor
b. The regular lamellae of c. Choroid
collagen fibers of the cornea d. Vitreous body
merge with the irregular
collagen bundles of the sclera 12. All of the following are true
c. The bowman’s membrane is concerning the ciliary body
replaced by subconjunctival except:
connective tissue a. It’s present at the limbus
d. The descemt’s membrane and b. The apex of the triangle is
corneal endothelium become continuous anteriorly with
continuous with the the choroid
discontinuous layer of c. The base faces the anterior
fibroblasts and melanocytes of chamber
the sclera d. The outer surface faces the
sclera
9. ………….. pierces the sclera :
a. Optic nerve fibers 13. The ciliary epithelium is arranged
b. Ciliary nerves and vessels into 2 layers outer non-pigmented
c. Central artery of the retina layer and inner pigmented one
d. All of the above a. True
b. False
10. All of the following are related to
the sclera except: 14. All of the following is true
a. Conjunctiva concerning the ciliary muscles
b. Choroid except:
c. Ciliary vessels a. Arranged into 3 groups
meridional, circular and radial
 

b. Responsible for b. orra serrata, optic disk


accommodation for near vision
c. Receive parasympathetic 19. the temporal and nasal branches
supply from the occulomotor of the superior division of the
nerve central artery of the retina
d. Attached to the lens via the anatomize with those of the
zonules inferior division to supply the
different parts of the retina
15. The anterior chamber lies between a. true
the lens and the iris while the b. false
posterior chamber lies between
the iris and the cornea 20. The circulus arteriosus major and
a. True minor supply …………..
b. False a. choroid
b. ciliary body
16. ………… are arranged in circules c. sclera
concentric to the pupil d. iris
a. Dilator pupillae muscles
21. Which of the following statements
b. Constrictor pupillae muscles
isn't correct about the outer
portion of the retina:
17. …………….. forms the capsule of a. Formed of pigmented
the lens epithelium
a. Basement membrane material b. it is photosensitive
b. Reticular fibers c. it is firmly attached to the
c. Collagen fibers choriocapillary layer of the
d. a and b
choroid.
e. a and c
22. All of the following statements
about the fovea centralis are
18. The retina extends from …………
correct except
posteriorly to ……………..
a. shallow depression
anteriorly
b. located 2.5 mm lateral to the
a. optic disk, orra serrata
optic disc
 

c. It is the area of greatest visual 26. Which of the following statements


acuity. is incorrect about the Rod cells
present in the retina
d. called also optic papilla
a. mediate night vision
23. tight junctions in the Retinal b. contains rhodopsin
Pigmented epithelial cells are c. extremely sensitive to light
present between:
d. doesn't have outer fibers
a. numerous invaginations of the
cell base and basal lamina 27. It contains the synapses between
b. The adjacent cell membranes the synaptic processes of rod and
cone cells and the dendrites of the
of cells
bipolar cells and horizontal cells.
c. The cell apex and the rods and
a. Retinal Pigmented epithelium
cones
b. Inner plexiform layer
c. The outer plexiform layer
24. the blood retinal barrier is formed
d. The outer limiting membrane
from tight junctions between
adjacent cells of Retinal Pigmented 28. cell bodies with the nuclei of the
epithelial cells with the tight bipolar cells are present in
junctions between endothelial cells a. Retinal Pigmented epithelium
of retinal blood vessels
b. Inner nuclear layer
a. true
c. The outer nuclear layer
b. false
d. The outer limiting membrane

25. the layer of the retina that has a 29. Cells that extend from the outer to
role in Participation in restoration the inner limiting membranes. It
of photosensitivity to visual has supportive, protective and
pigments is nutritive functions.
a. Retinal Pigmented epithelium a. Horizontal cells
b. Inner plexiform layer b. Muller cells
c. The outer plexiform layer c. Amacrine cells
d. The outer limiting membrane
30. few large cells with vesicular
nucleus and basophilic cytoplasm
and The retinal blood capillaries
are present between them
 

a. Ganglion nerve cells. 35. Muller muscle is inserted in the


b. Horizontal cells superior border of the tarsal plate
and is supplied by
c. Supporting cells
parasympathetic nerves
d. Amacrine cells
a. True

31. myelin of the optic nerve fiber is b. False


formed by
a. melanocytes 36. The following are modified
b. oligodendrocytes sebaceous glands except:
c. muller cells a. Meibomian glands

d. Schwann cells. b. Zeis gland


c. Glands of Moll

32. Conjunctiva is made up of


37. Between the vestibular scala and
a. non keratinized stratified
the middle scala is:
squamous epithelium
b. keratinized stratified squamous a. Reissner's membrane.
epithelium b. The basilar membrane.
c. The stria vascularis.
c. simple columnar epithelium
d. The spiral ganglion.
d. simple cuboidal epithelium

38. Between the middle scala and the


33. Conjunctiva helps in defending
tympanic scala is:
the eye against infection.
a. True a. Reissner's membrane
b. False b. The basilar membrane
c. The stria vascularis.
d. The spiral ganglion.
34. Levator palpebrae superioris
muscle is supplied by
a. Occulomotor nerve 39. The stria vascularis is found in:
b. Optic nerve
a. The middle scala.
c. Trochlear nerve
b. The vestibular scala.
d. Abduscent nerve c. The tympanic scala.
d. The modiolus..
 

40. The ogan of Corti is found in:

a. The middle scala.


b. The vestibular scala.
c. The tympanic scala.
d. The modiolus.
 

Answers: 32. A
33. A
1. C 34. A
2. C 35. B
3. C 36. C
4. A 37. A
5. A 38. B
6. B 39. A
7. D 40. A
8. D
9. D
10. D
11. C
12. B
13. B
14. C
15. B
16. B
17. D
18. A
19. B
20. D
21. B
22. D
23. B
24. A
25. A
26. D
27. C
28. B
29. B
30. A
31. B
 

6. The distance between the lens and


the principale focus is :
a. principale focal distance
b. principale axis
c. principale focus
d. none of the above
Physiology of special senses:
7. The rays from an object less than 6
meters are parallel:
1. Bouncing of light rays of a surface:
a. true
a. refraction
b. false
b. reflection
c. absorption
8. The refractive power of a lens is
d. none of the above
measured in :
a. m
2. The transfer of L ight energy to a
b. mm
particle or surface:
c. nm
a. refraction
d. diopters
b. absorption
c. reflection
9. The refractive media of the eye is
d. none of the above
formed of :
a. cornea
3. When light passes from one
b. lens
transparent medium to another ,its
c. aqueous and vitreous humor
speed is constant:
d. all of the above
a. true
b. false
10. The refractive index of cornea is :
a. 1.38
4. The greater the incident angle and
b. 1.4
the greater the difference in
c. 1.33
refractive indices ,the lesser is the
d. 1.36
bending or refraction
a. true
11. The refractive power of cornea is
b. false
…….diopters:
a. 20
5. A line passing through the centers
b. 40
of curvature of the lens :
c. 30
a. principale focus
d. none of the above
b. principale focal distance
c. principale axis
12. The refractive index of lens is ….
d. none of the above
a. 1.36
 

b. 1.38 b. false
c. 1.4
d. 1.33 19. The center of corneal reflex is
located in :
a. midbrain
13. The refractive power of lens is b. pons
……..diopters: c. medulla oblongata
a. 20 d. none of the above
b. 40
c. 30 20. The effector of the corneal reflex is
d. none of the above :
a. orbicularis oculi
14. The total refractive power of the b. medial rectus
human eye during accommodation c. ciliary
is 60 diopters: d. all of the above
a. true
b. false 21. The aqueous humor controls the
intraocular volume and pressure:
15. Cornea and lens are the chief a. true
refractive media of the eye : b. false
a. true
b. false 22. The lens is vascular transparent
biconvex structure :
16. The most important part of the a. a.true
refractive power of the eye is : b. b.false
a. lens
b. cornea 23. Clear gelatinous material filling
c. aqueous humor the space between the posterior
d. all of the above surface of the lens and the retina :
a. vitreous humor
b. aqueous humor
17. The refractive index of the cornea
c. all of the above
is slightly different from that of the
d. none of the above
air:
a. true
b. false 24. Blurred vision is the stimulus for
accommodation reflex:
18. Protection is the main importance a. true
of corneal reflex: b. false
a. true
 

25. The recession of the near vision e. All of the above


with age is called:
a. myopia
28. At maximal light intensity the
b. hyperopia
c. presbypia membrane potential can reach
d. none of the above - 70 mV. this inhibits the
release of neurotransmitter
glutamate Thus in bipolar cells

26. All of the following events can fire an action potential

occur during darkness except: a. True

a. cGMP binds to cation channels b. False

in the outer segments of


photoreceptors 29. All of the following statements

b. photoreceptors are depolarized about the retinal adaptation are

c. there is continuous glutamate correct except:

release by photoreceptors at a. It depends on the

their synapses with the bipolar concentration of the

cells. . photosensitive chemicals in the

d. channels in rod's outer rods and cones

segment close. b. Light adaptation can occur

e. Cation influx in the outer more rapid than dark

segment now decreases, while adaptation

Na+ ions continue to be c. The sensitivity of the retina In

pumped out from the inner darkess is lower than its

segment sensitivity in light

f. Ca+2 ions are removed by the d. Light adaptation is due to the

Na+-Ca2+ exchange carrier. break down of the


photosensitive chemicals in the

27. The output neuron of the retina rods and cones

a. The photoreceptors
b. bipolar cells 30. All of the following occurs

c. The ganglion cells during dark adaptation except:

d. A and b a. Visual acuity is small


 

b. all the retinal and opsins in 34. The scala vestibuli and the
rods and cones are converted media are separated from each
into light sensitive pigments other by the
c. Increase in retinal sensitivity to a. Reissner's membrane
light b. basilar membrane
d. the retinal is converted into c. tympanic membrane
vitamin A d. tectorial membrane

31. which of the following 35. The endolymph:

statements is correctly a. formed by stria vascularis

describing nyctalopia b. present in scalae vestibule and

a. optic nerve function is tympani

seriously hampered c. electronegative compared to

b. the most common cause of perilymph

night blindness is prolonged d. similar in composition to the

vitamin A deficiency extracellular fluid

c. the rods and cons cann't 36. The primary auditory cortex:
perform their normal a. is called broca's area
functions b. receives information from both
d. occurs due to abnormal gene cochlea
on the X-chromosome c. show no regional localization of
the cochlea
32. Exposure to light activates d. can appreciate significance of
phosphodiestrase enzyme PDE the spoken words
that breaks cGMP into 5' GMP e. present in the parietal lobe in
a. True the floor of the central sulcus
b. False
37. About the intensity of sound all
of the following is true except:
33. Dark adaptation occurs four
a. measured in decibels
times as rapidly in rods as in
b. determined by amplitude of
cons
sound waves
a. True
c. perceived as loudness of sound
b. False
 

d. not affected by the frequency of d. contraction of tympani and


sound waves relaxation of stapedius
e. none of the above
38. The basilar membrane of the
cochlea 41. The length of the fibers of the
a. cover oval and round windows The basilar membrane decrease
b. separates scalae vestibule and progressively from the base
tympani towards the apex of the cochlea
c. vibrates in pattern determined a. True
by the form of travelling waves b. False
in the cochlear perilymph
42. The rods of corti support:
39. Auditory discrimination of a a. The reticular lamina
certain sound pich depends b. Tectorial membrane
upon: c. Basilar membrane
a. part of the basilar membrane
43. Helicotrema is an opening that
maximally displaced by the
connects:
sound wave
a. scalae vestibule and tympani
b. frequency of sound waves
b. scalae vestibule and media
c. difference in the middle ear
c. scalae media and tympani
amplification of sounds of
different piches 44. When the basilar membrane
d. a and b but not c moves up, the reticular lamina
e. a,b and c moves up and in away from the
modiolus
40. Attenuation reflex caused by
a. True
loud voice leads to:
b. False
a. contraction of both stapedius
and tensor tympani muscles 45. Depolarization of the hair cells
b. relaxation of the above 2 depends mainly on:
muscles a. Outflux of Cl
c. contraction of stapedius and b. Influx of Na
relaxation of tympani c. Influx of K
d. Outflux of K
 

46. (Choose the incorrect answer) 49. The tonotopic organization


Sound localization In the present in the organ of Corti is
horizontal plane : preserved within the cochlear
a. Doesn't Require bilateral nuclei, the inferior colliculus
hearing and the primary auditory area
b. It is a function of the superior a. True
olivary nucleus and the primary b. False
auditory cortex
c. Detect the difference in the
50. Most of the information leaving
intensity of sound between the
the cochlea to the auditory
two ears.
pathway comes from
d. detect the time lag between the
a. the inner hair cells
entry of sound into one ear and
b. the outer hair cells
its entry into opposite ear
c. both of the hair cells are equally
through the presence of time lag
discharging
neurons

47. It is a center for (audiospinal 51. olfactory sensory receptors


reflexes). located in:
a. Auditory cortex a. in a ganglion
b. Inferior colliculus
b. in olfactory mucosa
c. Superior olivary nucleus
d. Cochlea c. in taste mucous membrane

48. Unilateral lesion of the primary


auditory cortex 52. surface area covered by the
a. gives total deafness yellowish pigmented olfactory
b. unilateral deafness on the mucous membrane in
ipsilateral side microsomatic animals:
c. does not lead to deafness in
a. large area
either ear
d. The person cannot interpret the b. 10 squares cm
meaning of the sound.
c. 5 squares cm
 

d. None of the above 56. The dendrites of neurons of


olfactory receptors:

53. surface area covered by the a. Thick & long


yellowish pigmented olfactory
b. Thick & short
mucous membrane in
macrosomatic animals: c. Thin & long

a. large area d. Thin & short

b. 10 squares cm
57. Cilia of olfactory receptors:
c. 5 squares cm
a. Myelinated with 0.1µm in
d. None of the above
diameter

b. Myelinated with 2µm in


54. pigmented olfactory mucous
diameter
membrane contain:
c. Unmyelinated with 0.1µm
a. supporting cells
in diameter
b. progenitor cells
d. Un myelinated with 2 µm
c. both A & B in diameter

d. none of the above


58. Olfactory membrane covered
by mucous membrane secreted
55. between supporting &
by:
progenitor cells of pigmented
olfactory mucous membrane: a. Schwann cells

a. 10-20 thousands receptors b. Olfactory cells

b. 10-20 millions receptors c. Nasal membrane

c. 10-20 hundreds receptors d. Bowman's glands

d. 10-20 receptors
59. Olfactory cells can't regenerate:
 

a. True b. by drugs

b. False c. by conditions

d. all of the above


60. Olfactory cells stimulated by:

a. Odorant molecules 64. the main structure responsible


for discriminate odors:
b. Taste molecules
a. olfactory mucosa
c. None of the above
b. olfactory genes

61. Receptor-odorant complex c. olfactory glomeruli


stimulate:
d. all of the above
a. adenylate cyclase

b. Odorant molecule 65. Olfactory signals become


topographically organized
c. G-protein ( Golf )
within:
d. Na+/ Ca2+ channels
a. olfactory glomeruli

b. olfactory mucosa
62. adenylate cyclase cause:
c. both A & B
a. adenylate cyclase
d. olfactory bulb
b. formation cAMP

c. G-protein ( Golf )
66. adaptation of olfactory system:
d. Na+/ Ca2+ channels
a. rapid and at CNS level

b. rapid and at receptor level


63. spasticity of olfactory
epithelium controlled by: c. slow and at CNS level

a. genetically d. both A & B


 

67. the constitutions of chemical e. Ketones & Sugars & Glycols


sense: & Alcohols

a. Olfaction
70. sweet taste caused by:
b. Gustation
a. ionized salts
c. Both A & B
b. acids
d. None of the above
c. long chain organic
substances contain
68. the common character of smell
alkaloids
& taste:
d. foods containing glutamate
a. provide information
regarding the external e. Ketones & Sugars & Glycols
environment & Alcohols

b. replaced with a half-time


of a few weeks 71. Sour taste caused by:

c. specialized sensory a. ionized salts


receptors are stimulated by
b. acids
chemical molecules
c. long chain organic
d. all of the above
substances contain
alkaloids
69. sweet taste caused by:
d. foods containing glutamate
a. ionized salts
e. Ketones & Sugars & Glycols
b. acids & Alcohols

c. long chain organic


substances contain 72. Bitter taste caused by:
alkaloids
a. ionized salts
d. foods containing glutamate
b. acids
 

c. long chain organic b. palate, pharynx


substances contain
c. epiglottis
alkaloids
d. All of the above
d. foods containing glutamate

e. Ketones & Sugars & Glycols


76. Damage to the nerves
& Alcohols
innervating the taste buds
cause:
73. Umami taste caused by:
a. Total ageusia
a. ionized salts b. Partial ageusia
c. Both A & B
b. acids
d. None of the above
c. long chain organic
substances contain
77. innervation of taste buds on
alkaloids
anterior 2/3 of tongue:
d. foods containing glutamate
a. facial nerve (CN VII)
e. Ketones & Sugars & Glycols b. glossopharyngeal nerve
& Alcohols ( CN IX )
c. Vagus nerve (CN X).
74. receptors of taste sensation
located in:
78. the innervation of taste buds on
a. taste buds
posterior 1/3 of tongue:
b. olfactory epithelium
a. facial nerve (CN VII)
c. skin
b. glossopharyngeal nerve
d. all of the above ( CN IX )

c. Vagus nerve (CN X)


75. taste buds located in:

a. papillae 79. the innervation of taste buds on


epiglottis
 

a. facial nerve (CN VII)

b. glossopharyngeal nerve (
CN IX )

c. Vagus nerve (CN X)


 

Answers: 31. B
32. A
33. B
1. B
34. A
2. B
35. A
3. B
36. B
4. B
37. D
5. C
38. C
6. A
39. D
7. B
40. A
8. D
41. B
9. D
42. A
10. A
43. A
11. B
44. B
12. C
45. C
13. A
46. A
14. B
47. B
15. A
48. C
16. B
49. A
17. B
50. A
18. A
19. B 51. B
20. A
52. C
21. A
22. B 53. A
23. A
54. C
24. A
25. C 55. B
26. E
56. B
27. C
28. B 57. C
29. C
58. D
30. D
 

59. B

60. A

61. C

62. B

63. A

64. C

65. D

66. D

67. C

68. D

69. E

70. A

71. B

72. C

73. D

74. A

75. D

76. C

77. A

78. B

79. C
 
 

Chapter 4: d. terbutaline (Brethine)

6. Nerve terminal reuptake inhibitor


Pharmacology bank Qs ;)
a. methoxamine (Vasoxyl)
b. cocaine
1. ANS:
c. reserpine
1. Drugs activating this receptor are d. timolol (Blocadren)
used in treating asthma:
a. beta1 adrenergic 7. Alpha adrenoceptor COVALENT
b. muscarinic cholinergic blocker:
c. beta2 adrenergic a. propranolol (Inderal)
d. nicotinic cholinergic b. phenoxybenzamine
(Dibenzyline)
2. Epinephrine effects on the heart c. phentolamine (Regitine)
a. increased rate d. pilocarpine (Pilocar)
b. decreased contractility
c. coronary vasodilation 8. Orthostatic (postural)
d. A & C hypotension
a. beta receptor activation
3. Receptor activation mainly b. alpha receptor activation
responsible for positive c. alpha receptor blocker
inotropism: d. dopamine receptor blockade
a. alpha1
b. beta1 9. Norepinephrine pressor response
c. dopamine D1 blocked by:
d. muscarinic cholinergic a. mecamylamine (Inversine)
b. prazosin (Minipress)
4. Epinephrine effects on c. atropine
respiration: d. propranolol (Inderal)
a. stimulation
b. Inhibition 10. Positive chronotropic effects of
epinephrine:
5. Activates alpha receptors a. increased SA nodal potassium
a. isoproterenol (Isuprel) current
b. propranolol (Inderal) b. beta1 receptor activation
c. phenylephrine (Neo- c. mediated by G protein
Synephrine) d. B&C
 

11. Pressor effects of epinephrine are b. cocaine increases conversion


blocked by this drug of norepinephrine to
("epinephrine reversal") phenylephrine
a. propranolol (Inderal) c. cocaine decreases cholinergic
b. phentolamine (Regitine) receptor number
c. phenylephrine (Neo- d. cocaine decreases N.E.
Synephrine) metabolism by MAO
d. metoprolol (Lopressor) e. cocaine increases N.E.
receptor number
12. Decreases blood pressure
a. propranolol (Inderal) 16. Immediate biosynthetic precursor
b. mecamylamine (Inversine) of epinephrine:
c. phentolamine (Regitine) a. L-DOPA
d. all of the above b. doapmine
c. norepinephrine
13. Centrally-acting antihypertensive d. metaraminol
drug e. Isoproterenol
a. nitroprusside sodium
(Nipride) 17. Epinephrine:
b. clonidine (Catapres) a. limited effect on alpha
c. methoxamine (Vasoxyl) receptors
d. captopril (Capoten) b. increases heart rate,
contributing to increase blood
14. Therapeutic use of esmolol pressure
(Brevibloc): c. epinephrine often reduces
a. bronchial asthma peripheral vascular resistance,
b. renal vasodilator especially at high
c. antihypertensive concentration
d. antiarrhythmic drug d. epinephrine tends to exhibit
e. positive inotrope in CHF negative inotropic effects
e. all of the above
15. The magnitude of the
cardiovascular response to 18. Vasoconstrictive effects of
norepinephrine is increased by epinephrine:
cocaine because: a. alpha-1 adrenergic receptor-
a. cocaine inhibits mediated affecting precapillary
norepinephrine reuptake resistance vessels of the skin,
kidney, and mucosa
 

b. veins e. all of the above


c. both
d. Neither 23. Significant respiratory tract
effects of epinephrine:
19. A decrease in diastolic pressures a. beta-2 receptor mediated
associated with epinephrine bronchoconstriction
administration would most likely b. alpha-1 receptor-mediated
occur in which dosage? bronchodilation
a. relatively high doses c. beta-1 receptor-mediated
b. relatively low doses bronchodilation
d. beta-2 receptor-mediated
20. Most probable BP effect of bronchodilation
epinephrine, if epinephrine is
administered after an alpha- 24. Examples of epinephrine
receptor antagonist: metabolic effects
a. previous administration of a. insulin secretion reduced by
the alpha-receptor antagonist beta2 adrenergic receptor
will not influence the blood- activation
pressure response to b. glucagon secretion:
epinephrine diminished by beta adrenergic
b. increased blood-pressure receptor activation
response to epinephrine c. free fatty acids: increased
c. decreased blood-pressure d. minimal calorigenic effect
response to epinephrine e. glycolysis inhibition

21. Prominent cardiac beta- 25. Toxicities/adverse reactions


adrenergic receptor type: associated with
a. beta-1 sympathomimetics
b. beta-2 a. angina
c. beta-3 b. hypertension; cerebral
hemorrhage
22. Cardiac effects associated with c. cardiac arrhythmias
epinephrine: d. anxiety reactions
a. positive chronotropic e. all the above
b. positive inotropic
c. increased cardiac output 26. Drugs antagonize epinephrine
d. increased oxygen pressor effects:
consumption a. phentolamine (Regitine)
 

b. terbutaline (Brethine) b. heart rate cannot decrease


c. dopamine (Intropin) following norepinephrine
d. dobutamine (Dobutrex) infusion because
e. Atropine norepinephrine activates beta-
1 adrenergic receptors
27. Epinephrine effects on AV nodall c. activation of the baroreceptor
conduction: system causing a reflex-
a. increased conduction velocity mediated decrease in heart
b. decreased conduction velocity rate
c. promotes AV block d. peripheral vasodilation
e. none of the above
28. Ventricular effects associated
with epinephrine administration: 31. Vascular effects of
a. increased automaticity norepinephrine (Levophed):
b. increased ectopic pacemaker a. significantly decreases
activity glomerularl filtration rates
c. increased conduction b. effective in treating variant
philosophy (Prinzmetal's) angina
d. increased contractility c. norepinephrine pressor
e. all the above effects blocked by prazosin
(Minipress)
29. Primary neurotransmitter d. increased blood flow to liver,
released by postganglionic kidney, and skeletal muscle
neurons of the autonomic
sympathetic system: 32. Immediate synthetic precursor of
a. epinephrine norepinephrine:
b. dopamine a. Epinephrine
c. dobutamine b. tyrosine
d. norepinephrine c. tyrosine hydroxylase
e. Phenylephrine d. dopamine
e. Dopa
30. Decreased heart rate following
norepinephrine infusion is most 33. CNS neurotransmitter associated
likely due to: with the basal ganglia and motor
a. direct norepinephrine control:
activation of muscarinic a. dopamine
receptors at the SA node b. acetylcholine
c. both
 

d. Neither a. low systemic blood pressure


b. decreased atrial filling
34. Low doses, this precursor of pressures
norepinephrine causes c. high urinary output
renovascular dilation:
a. epinephrine 38. Simultaneous increases in
b. dopa myocardial contractility,
c. dopamine (Intropin) glomerular filtration rate, sodium
d. dobutamine (Dobutrex) excretion, urine output, and renal
e. nitroprusside sodium blood flow are associated most
(Nipride) likely with:
a. epinephrine
35. Pharmacological action(s) of b. isoproterenol (Isuprel)
dopamine (Intropin): c. phenylephrine (Neo-
a. positive inotropism Synephrine)
b. promotes myocardial d. dopamine (Intropin)
norepinephrine release e. norepinephrine (Levophed)
c. increases glomerular
filtration rates (low-dose) 39. Properties of dobutamine
d. vasoconstriction by alpha-1 (Dobutrex):
receptor activation (high-dose) a. positive inotropic agent;
e. all the above causes significant increase in
heart rate
36. Significant therapeutic use for b. promotes catecholamine
dopamine: release
a. management of sleep cycles c. mainly acts through
b. treatment of Raynaud's dopamine receptors
phenomenon d. positive inotropic effect is
c. treatment of mediated through beta-
cardiogenic/hypovolemic adrenergic receptor activation
shock e. appropriate for long-term
d. management of management of myocardial
tachyarrhythmias pump-failure following
surgery
37. Cardiovascular characteristics of
patients who might benefit from 40. Examples of beta-2 selective
IV dopamine (Intropin) adrenergic agonists
administration: a. metaproterenol (Alupent)
 

b. terbutaline (Brethine) c. cardiac output obstruction


c. albuterol (Ventolin,Proventil) d. loss of peripheral vascular
d. A&B tone
e. A, B & C e. all of the above

41. Clinical use(s) of alpha-1- 45. Most likely to reduce myocardial


receptor agonists: performance in a damaged heart
a. management hypotensive by increasing afterload:
states a. isoproterenol (Isuprel)
b. termination of paroxysmal b. phenylephrine (Neo-
atrial tachycardia Synephrine)
c. nasal decongestant c. low-dose dopamine
d. A&B (Intropin)
e. A,B & C d. low-dose epinephrine

42. Primary use for alpha-2-selective 46. Receptor system most likely
adrenergic agonists: responsible for improved
a. to manage hypotensive states myocardial contractility when
b. to increase myocardial dopamine is administered at low
contractility concentrations:
c. to reduce blood pressure a. muscarinic cholinergic
d. A & B receptors
e. A,B & C b. alpha adrenergic receptors
c. beta adrenergic receptors
43. Major mechanism of d. dopamine receptors (D1)
antihypertensive effects e. leukotriene receptors
associated with alpha-2-selective
adrenergic agonists: 47. Clinical applications of beta-
a. competitive inhibition of adrenergic antagonists:
vascular alpha receptors a. management of coronary
b. reduced sympathetic outflow vascular disease
b. treatment of arrhythmias
44. Clinical uses for c. treatment of hypertension
sympathomimetic drugs: d. all the above
a. hypovolemic shock caused
by dehydration or blood loss 48. A non-selective beta-adrenergic
b. cardiogenic shock (pump receptor blocker:
failure) a. metoprolol (Lopressor)
 

b. atenolol (Tenormin) a. epinephrine


c. timolol (Blocadren) b. isoproterenol (Isuprel)
d. esmolol (Brevibloc) c. cromolyn sodium (Intal)
d. beclomethasone (Banceril)
49. Beta-adrenergic receptor e. albuterol
blockers: effects on the heart -- (Ventolin,Proventil)
a. increase heart rate
b. increased AV nodal refractory 53. Used to suppress premature
period labor:
c. increased contractility
a. isoproterenol (Isuprel)
d. increased myocardial oxygen
b. losartin (Cozaar)
demand
c. ritodrine (Yutopar)
e. increased phase 4
d. phenylephrine (Neo-
depolarization
Synephrine)
e. clonidine (Catapres)
50. Most likely to cause dangerous
bronchiolar constriction in 54. Produces epinephrine reversal,
asthmatic patients or patients converting a pressor response to a
with COPD deep pressor response:
a. metoprolol (Lopressor)
b. propranolol (Inderal) a. losartin (Cozaar)
c. esmolol (Brevibloc) b. propranolol (Inderal)
d. atenolol (Tenormin) c. metoprolol (Lopressor)
d. phentolamine (Regitine)
51. Very potent beta adrenergic e. clonidine (Catapres)
receptor agonists with minimal
effects on alpha adrenergic 55. Choose the incorrect statement
receptors: concerning metabolic effects of
a. propranolol (Inderal) sympathomimetic agents
propranolol (Inderal)
a. Activation of beta receptors
b. isoproterenol (Isuprel)
in fat cells increase lipolysis.
c. epinephrine
b. Alpha -- 2 adrenergic
d. yohimbine (Yocon)
receptors inhibit lipolysis
e. phentolamine (Regitine)
c. Hepatic catecholamine
effects our mediated mainly by
52. Beta-2 selective agonist--
beta adrenergic receptor
typically administered by aerosol
activation
for asthma management:
 

d. At high concentrations, a. Release of norepinephrine


catecholamines may induce a from nerve terminals
metabolic acidosis b. Activation of adrenoreceptors
e. Sympathomimetic drugs on postsynaptic sites
increase extracellular c. Release of epinephrine from
potassium the adrenal medulla
d. All of the above
56. Correct receptor type: tissues --
actions 59. Characteristics of epinephrine
include all of the following
a. alpha 1: heart: positive
EXCEPT:
inotropic
a. It is synthesized into the
b. alpha 1: pupillary dilator
adrenal medulla
muscle: miosis (pupillary
b. It is synthesized into the nerve
contraction)
ending
c. alpha 2:cholinergic nerve
c. It is transported in the blood to
terminals: facilitate transmitter
target tissues
release
d. It directly interacts with and
d. beta 1: heart: decrease
activates adrenoreceptors
forests of contraction
e. beta 2:human liver: inhibits
60. Which of the following
glycogenolysis
sympathomimetics acts
57. Correct receptor type: tissues: indirectly?
actions a. Epinephrine
b. Norepinephrine
a. alpha 1:most innervated c. Ephedrine
vascular smooth muscle: d. Methoxamine
contraction
b. alpha 2:platelets: 61. Indirect action includes all of the
aggregation following properties EXCEPT:
c. beta 2:uterine smooth a. Displacement of stored
muscle: smooth muscle catecholamines from the
relaxation adrenergic nerve ending
d. A&C b. Inhibition of reuptake of
e. A, B & C catecholamines already
released
58. Sympathetic stimulation is c. Interaction with
mediated by: adrenoreceptors
 

d. Inhibition of the release of Norepinephrine


endogenous catecholamines
from peripheral adrenergic 65. Direct effects on the heart are
neurons determined largely by:
a. Alfa1 receptor
62. Catecholamine includes following b. Alfa2 receptor
EXCEPT: c. Beta1 receptor
a. Ephedrine d. Beta2 receptor
b. Epinephrine
c. Isoprenaline 66. Which of the following effects is
d. Norepinephrine related to direct beta1-
adrenoreceptor stimulation?
63. Epinephrine decreases a. Bronchodilation
intracellular camp levels by b. Vasodilatation
acting on: c. Tachycardia
a. α1 receptor d. Bradycardia
b. α2 receptor
c. beta1 receptor 67. Distribution of alfa
d. beta2 receptor adrenoreceptor subtypes is
associated with all of the
64. Which of the following following tissues except those of:
statements is not correct? a. Heart
a. ALFA receptors increase arterial b. Blood vessels
resistence, whereas beta2 c. Prostate
receptor promote smooth d. Pupillary dilator muscle
muscle relaxation
b. The skin and splanchic vessels 68. Beta adrenoreceptor subtypes is
have predominantly alfa contained in all of the following
receptors tissues EXCEPT:
c. Vessels in a skeletal muscle may a. Bronchial muscles
constrict or dilate depending on b. Heart
whether alfa or beta2 receptors c. Pupillary dilator muscle
are activated d. Fat cells
d. Skeletal muscle vessels have
predominantly alfa receptors 69. In which of the following tissues
and constrict in the presence of both alfa and beta1 adrenergic
epinephrine and stimulation produces the same
effect?
 

a. Blood vessels d. Αlfa agonists increase the


b. Intestine outflow of aqueous humor
c. Uterus from the eye
d. Bronchial muscles
74. A bronchial smooth muscle
70. The effects of sympathomimetics contains:
on blood pressure are associated a. Αlfa1 receptor
with their effects on: b. Αlfa2 receptor
a. The heart c. c) Beta 1 receptor
b. The peripheral resistance d. Beta 2 receptor
c. The venous return
d. All of the above 75. All of the following agents are
beta receptor agonists EXCEPT:
71. A relatively pure alfa agonist a. Epinephrine
causes all of the following effects b. Isoproterenol
EXCEPT: c. Methoxamine
a. Increase peripheral arterial d. Dobutamine
resistance
b. Increase venous return 76. Αlfa-receptor stimulation
c. Has no effect on blood vessels includes all of the following
d. Reflex bradycardia effects EXCEPT:
a. Relaxation of gastrointestinal
72. A nonselective beta receptor smooth muscle
agonist causes all of the following b. Contraction of bladder base,
effects EXCEPT: uterus and prostate
a. Increase cardiac output c. Stimulation of insulin
b. Increase peripheral arterial secretion
resistance d. Stimulation of platelet
c. Decrease peripheral arterial aggregation
resistance
d. Decrease the mean pressure 77. Beta1 receptor stimulation
includes all of the following
73. Which of the following statement effects EXCEPT:
is not correct? a. Increase in contractility
a. Αlfa agonists cause miosis b. Bronchodilation
b. Αlfa agonists cause mydriasis c. Tachycardia
c. Beta antagonists decrease the d. Increase in conduction
production of aqueous humor velocity in the
 

atrioventricular node d. Isoprenaline has a


predominantly beta action
78. Beta2 receptor stimulation
includes all of the following 82. Indicate the drug, which is a
effects EXCEPT: direct-acting both alfa- and beta-
a. Stimulation of renin receptor agonist:
secretion a. Norepinephrine
b. Fall of potassium b. Methoxamine
concentration in plasma c. Isoproterenol
c. Relaxation of bladder, uterus d. Ephedrine
d. Tachycardia
83. Which of the following agents is
79. Hyperglycemia induced by an alfa1 alfa2 beta1 beta2
epinephrine is due to: receptor agonist?
a. Gluconeogenesis (beta2) a. Methoxamine
b. Inhibition of insulin b. Albuterol
secretion (alfa) c. Epinephrine
c. Stimulation of glycogenolysis d. Norepinephrine
(beta2)
d. All of the above 84. Indicate the direct-acting
sympathomimetic, which is an
80. Which of the following effects is alfa1 alfa2 beta1 receptor
associated with beta3-receptor agonist:
stimulation? a. Isoproterenol
a. Lipolysis b. Ephedrine
b. Decrease in platelet c. Dobutamine
aggregation d. Norepinephrine
c. Bronchodilation
d. Tachycardia 85. Which of the following agents is
a nonselective beta receptor
81. Which of the following agonist?
statements is not correct? a. Norepinephrine
a. Epinephrine acts on both b. Terbutaline
alfa- and beta-receptors c. Isoproterenol
b. Norepinephrine has a d. Dobutamine
predominantly beta action
c. Methoxamine has a 86. Indicate the beta1-selective
predominantly alfa action agonist:
 

a. Isoproterenol d. Mydriasis
b. Dobutamine
c. Metaproterenol 91. Epinephrine is used in the
d. Epinephrine treatment of all of the following
disorders EXCEPT:
87. Which of the following a. Bronchospasm
sympathomimetics is a beta2- b. Anaphylactic shock
selective agonist? c. Cardiac arrhythmias
a. Terbutaline d. Open-angle glaucoma
b. Xylometazoline
c. Isoproterenol 92. Compared with epinephrine,
d. Dobutamine norepinephrine produces all of
the following effects EXCEPT:
88. Indicate the indirect-acting a. Similar effects on beta1
sympathomimetic agent: receptors in the heart and
a. Epinephrine similar potency at an alfa
b. Phenylephrine receptor
c. Ephedrine b. Decrease the mean pressure
d. Isoproterenol below normal before
returning to the control value
89. Epinephrine produces all of the c. Significant tissue necrosis if
following effects EXCEPT: injected subcutaneously
a. Positive inotropic and d. Increase both diastolic and
chronotropic actions on the systolic blood pressure
heart (beta1 receptor)
b. Increase peripheral resistance 93. Norepinephrine produces:
(alfa receptor) a. Vasoconstriction
c. Predominance of alfa effects at b. Vasodilatation
low concentration c. Bronchodilation
d. Skeletal muscle blood vessel d. Decresed potassium
dilatation (beta2 receptor) concentration in the plasma

90. Epinephrine produces all of the 94. Which of the following direct-
following effects EXCEPT: acting drugs is a relatively pure
a. Decrease in oxygen alfa agonist, an effective
consumption mydriatic and decongestant and
b. Bronchodilation can be used to raise blood
c. Hyperglycemia pressure?
 

a. Epinephrine 98. 047. Characteristics of salmeterol


b. Norepinephrine include all of the following
c. Phenylephrine EXCEPT:
d. Ephedrine a. It is a potent selective
beta2 agonist
95. 044. Isoproterenol is: b. It causes uterine
a. Both an alfa- and beta- relaxation
receptor agonist c. It stimulates heart rate,
b. beta1-selective agonist contractility and
c. beta2-selective agonist cardiac output
d. Nonselective beta d. It is used in the therapy
receptor agonist of asthma

96. 045. Isoproterenol produces all of 99. 048. Characteristics of ephedrine


the following effects EXCEPT: include all of the following
a. Increase in cardiac EXCEPT:
output a. It acts primarily
b. Fall in diastolic and through the release of
mean arterial pressure stored cathecholamines
c. Bronchoconstriction b. It is a mild CNS
d. Tachycardia stimulant
c. It causes tachyphylaxis
97. 046. Characteristics of with repeated
dobutamine include all of the administration
following EXCEPT: d. It decreases arterial
a. It is a relatively beta1- pressure
selective synthetic
catecholamine 100. 049. Ephedrine causes:
b. It is used to treat a. Miosis
bronchospasm b. Bronchodilation
c. It increases c. Hypotension
atrioventricular d. Bradycardia
conduction
d. It causes minimal 101. 050. Compared with
changes in heart rate epinephrine, ephedrine produces
and systolic pressure all of the following features
EXCEPT:
 

a. It is a direct-acting to prolong the duration of


sympathomimetic infiltration nerve block:
b. It has oral activity a. Epinephrine
c. It is resistant to MAO b. Xylometazoline
and has much longer c. Isoproterenol
duration of action d. Dobutamine
d. Its effects are similar,
but it is less potent 106. 055. Which of the following
sympathomimetics is related to
102. 051. Which of the following short-acting topical decongestant
sympathomimetics is preferable agents?
for the treatment of chronic a. Xylometazoline
orthostatic hypotension? b. Terbutaline
a. Epinephrine c. Phenylephrine
b. Norepinephrine d. Norepinephrine
c. Ephedrine
d. Salmeterol 107. 058. Indicate the
sympathomimetic, which may be
103. 052. Indicate the useful in the emergency
sympathomimetic drug, which is management of cardiac arrest:
used in a hypotensive emergency: a. Methoxamine
a. Xylometazoline b. Phenylephrine
b. Ephedrine c. Epinephrine
c. Terbutaline d. Xylometazoline
d. Phenylephrine
108. 059. Which of the following
104. 053. Which of the following sympathomimetics is used in the
sympathomimetics is preferable therapy of bronchial asthma?
for the emergency therapy of a. Formoterol
cardiogenic shock? b. Norepinephrine
a. Epinephrine c. Methoxamine
b. Dobutamine d. Dobutamine
c. Isoproterenol
d. Methoxamine 109. 060. Indicate the agent of
choice in the emergency therapy
105. 054. Indicate the of anaphylactic shock:
sympathomimetic agent, which is a. Methoxamine
combined with a local anesthetic b. Terbutaline
 

c. Norepinephrine 114. Resistant to hydrolysis by


d. Epinephrine acetylcholinesterase
a. carbachol (carbamylcholine)
110. 061. Which of the following b. methacholine (Provocholine)
sympathomimetics is an effective c. both
mydriatic? d. neither
a. Salmeterol
b. Phenylephrine 115. Highest nicotinic receptor
c. Dobutamine activity among choline esters:
d. Norepinephrine a. acetylcholine
b. atropine
111. 062. The adverse effects of c. methacholine (Provocholine)
sympathomimetics include all of d. carbachol
the following EXCEPT:
a. Drug-induced 116. Associated with
parkinsonism parasympathetic activation
b. Cerebral hemorrhage or (direct effects):
pulmonary edema a. increase heart rate
c. Myocardial infarction b. decreased GI motility
d. Ventricular arrhythmias c. decrease cardiac contractility
d. urinary retention
112. Sympathetic Nervous System
a. Ganglionic neurotransmitter: 117. Miosis produced by
acetylcholine a. pilocarpine (Pilocar)
b. generalized response upon b. atropine
sympathetic activation c. both
c. thoraco-lumbar origin for d. neither
preganglionic cell bodies
d. A, B and C 118. Antimuscarinic drug with
highest CNS activity
113. Choline ester most susceptible a. atropine
to hydrolysis by b. scopolamine
acetylcholinesterase: c. homatropine
a. carbachol d. muscarine
b. acetylcholine
c. methacholine (Provocholine) 119. Muscarinic agent: enhances
d. pilocarpine (Pilocar) transmission through the A-V
node:
 

a. isoproterenol (Isuprel) d. A & C


b. atropine e. A, B & C
c. propranolol (Inderal)
d. methacholine (Provocholine) 124. Cholinergic receptor type
primarily localized at skeletal
120. Least likely to be used as a muscle neuromuscular junctions:
mydriatic because of long- a. muscarinic
duration of action: b. nicotinic
a. homatropine (Isopto
Homatropine) 125. Highly sensitive to the action
b. atropine of acetylcholinesterase:
c. cyclopentolate (Cyclogyl) a. carbachol
d. benztropine (Cogentin) b. bethanechol (Urecholine)
c. acetylcholine
121. Clinically-used to treat sinus d. A & C
bradycardia secondary to acute e. A,B, & C
myocardial infarction:
a. homatropine (Isopto 126. Muscarinic receptor subtype
Homatropine) primarily associated with the
b. atropine heart:
c. benztropine (Cogentin) a. M1
d. tropicamide (Mydriacyl) b. M2
c. M3
122. Location(s) of cholinergic d. M4
synaptic sites:
a. neuromuscular junction 127. Effective antagonist at
b. autonomic effector sites neuromuscular junction
innervated by post-ganglionic receptors;
sympathetic fibers a. atropine
c. some CNS synapses b. tubocurarine
d. A & C
128. Cardiac muscarinic Type M2-
123. Localization of muscarinic receptor mediated action(s):
cholinergic receptors: a. increased phase 4
a. postganglionic depolarization rate
parasympathetic effector sites b. increased AV nodal conduction
b. autonomic ganglia cells velocity
c. adrenal medulla
 

c. Decreased atrial and c. both


ventricular contractility d. neither
d. all the above
135. Which type of glaucoma
129. Ligand-gated ion channels: response to anticholinesterase
a. nicotinic treatment?
b. muscarinic a. primary
c. both b. secondary
d. neither c. congenital

130. Tends to cause fast responses: 136. Probable cause of myasthenia


a. nicotinic gravis:
b. muscarinic a. excessive synthesis of
cholinergic receptors
131. Agonist effects blocked by b. inadequate synthesis of
tubocurarine: acetylcholine
a. muscarinic receptors c. failure of acetylcholine
b. nicotinic receptors reuptake system
d. binding of anti--muscarinic
132. Indirect-acting receptor antibodies to the
cholinomimetic: muscarinic cholinergic
a. atropine receptor
b. edrophonium (Tensilon) e. binding of anti-nicotinic
c. carbachol receptor antibodies to the
d. acetylcholine nicotinic cholinergic receptor
e. ephedrine
137. Preferred anticholinergic drug
133. More lipophilic: when sedation is the principal
a. neostigmine (Prostigmin) objective, preoperatively:
b. most organophosphate a. atropine
acetylcholinesterase inhibitors b. glycopyrrolate (Robinul)
c. scopolamine
134. Consequences of
acetylcholinesterase inhibitor 138. Anticholinergic drug most
application to the conjunctiva likely to be used clinically to
a. relaxation of the pupillary promote bronchodilation:
sphincter muscle a. IV atropine
b. relaxation of the ciliary muscle b. aerosolized atropine
 

c. aerosolized ipratropium a. a) Heart


bromide (ipratropium b. b) Glands
(Atrovent)) c. c) Smooth muscle
d. scopolamine d. d) Endothelium
e. all of the above
144. Which of the following
139. Mydriasis without loss of cholinomimetics activates both
accommodation muscarinic and nicotinic
a. parasympatholytic receptors?
b. sympathomimetic a. a) Lobeline
b. b) Pilocarpine
140. Management of severe c. c) Nicotine
bradycardia and A-V block d. d) Bethanechol
associated with acute myocardial
infarction: 145. Indicate a cholinomimetic
a. atropine agent, which is related to direct-
b. neostigmine (Prostigmin) acting drugs:
a. a) Edrophonium
141. Acetylcholine is not a specific b. b) Physostigmine
neurotransmitter at: c. c) Carbachol
a. a) Sympathetic ganglia d. d) Isoflurophate
b. b) Sympathetic postganglionic
nerve endings 146. Characteristics of carbachol
c. c) Parasympathetic ganglia include all of the following
d. d) Parasympathetic EXCEPT:
postganglionic nerve endings a. a) It decreases intraocular
pressure
142. Muscarinic receptors are b. b) It causes mydriasis
located in: c. c) It exerts both nicotinic and
a. a) Autonomic ganglia muscarinic effects
b. b) Skeletal muscle d. d) It is resistant to
neuromuscular junctions acethylcholiesterase
c. c) Autonomic effector cells
d. d) Sensory carotid sinus 147. Acetylcholine is not used in
baroreceptor zone clinical practice because:
a. a) It is very toxic
143. Indicate the location of M2 b. b) The doses required are very
cholinoreceptor type: high
 

c. c) It is very rapidly hydrolyzed c) Acetylcholine


d. d) It is very costly d) Bethanechol

148. Parasympathomimetic drugs 153. Characteristics of pilocarpine


cause: include all of the following
a. a) Bronchodilation EXCEPT:
b. b) Mydriasis a) It is a tertiary amine alkaloid
c. c) Bradycardia b) It causes miosis and a
d. d) Constipation decrease in intraocular
149. Which of the following direct- pressure
acting cholinomimetics is mainly c) Causes a decrease in secretory
muscarinic in action? and motor activity of gut
a. a) Bethanechol d) It is useful in the treatment of
b. b) Carbachol glaucoma
c. c) Acetylcholine
d. d) None of the above 154. Which of the following
cholinomimetics is indirect-
150. Which of the following direct- acting?
acting cholinomimetics has the a) Lobeline
shortest duration of action? b) Edrophonium
a) Acetylcholine c) Pilocarpine
b) Methacholine d) Carbachol
c) Carbachol
d) Bethanechol 155. The mechanism of action of
indirect-acting cholinomimetic
151. Bethanechol has all of the agents is:
following properties EXCEPT: a) Binding to and activation
a) It is extremely resistant to of muscarinic or nicotinic
hydrolysis receptors
b) Purely muscarinic in its action b) Inhibition of the hydrolysis
c) It is used for abdominal urinary of endogenous
bladder distention acetylcholine
d) It exerts both nicotinic and c) Stimulation of the action of
muscarinic effects acetylcholinesterase
d) Releasing acetylcholine
152. A M-cholinimimetic agent is: from storage sites
a) Carbachol
b) Pilocarpine
 

156. Indicate a reversible 161. Сholinesterase inhibitors do


cholinesterase inhibitor: not produce:
a) Isoflurophate a) Bradycardia, no change or
b) Carbochol modest fall in blood pressure
c) Physostigmine b) Increased strength of muscle
d) Parathion contraction, especially in muscles
weakened by myasthenia gravis
157. Which of the following c) Miosis and reduction of
cholinesterase inhibitors is intraocular pressure
irreversible? d) Dramatic hypertension and
a) Physostigmine tachycardia
b) Edrophonium
c) Neostigmine 162. Which of the following
d) Isoflurophate cholinomimetics is commonly
used in the treatment of
158. Indicate cholinesterase glaucoma?
activator: a) Pilocarpine
a) Pralidoxime b) Lobeline
b) Edrophonium c) Acethylcholine
c) Pilocarpine d) Neostigmine
d) Isoflurophate
163. Which of the following
159. Isofluorophate increases all of cholinomimetics is most widely
the following effects except: used for paralytic ileus and atony
a) Lacrimation of the urinary bladder?
b) Bronchodilation a) Lobeline
c) Muscle twitching b) Neostigmine
d) Salivation c) Pilocarpine
d) Echothiophate
160. Indicate a cholinesterase
inhibitor, which has an additional 164. Chronic long-term therapy of
direct nicotinic agonist effect: myasthenia is usually
a) Edrophonium accomplished with:
b) Carbochol a) Edrophonium
c) Neostigmine b) Neostigmine
d) Lobeline c) Echothiophate
d) Carbachol
 

165. Which of the following 169. The excessive stimulation of


cholinomimetics is a drug of muscarinic receptors by
choice for reversing the effects of pilocarpine and choline esters is
nondepolarizing neuromuscular blocked competitively by:
relaxants? a) Edrophonium
a) Echothiophate b) Atropine
b) Physostigmine c) Pralidoxime
c) Edrophonium d) Echothiophate
d) Pilocarpine
170. The toxic effects of a large dose
166. Indicate the reversible of nicotine include all of the
cholinesterase inhibitor, which following EXCEPT:
penetrates the blood-brain a) Hypotension and bradycardia
barrier: b) Convulsions, coma and respiratory
a) Physostigmine arrest
b) Edrophonium c) Skeletal muscle depolarization
c) Neostigmine blockade and respiratory paralysis
d) Piridostigmine d) Hypertension and cardiac
167. Which of the following arrhythmias
cholinomimetics is used in the
treatment of atropine 171. The dominant initial sights of
intoxication? acute cholinesterase inhibitors
a) Neostigmine intoxication include all of the
b) Carbochol following except:
c) Physostigmine a) Salivation, sweating
d) Lobeline b) Mydriasis
c) Bronchial constriction
168. The symptoms of excessive d) Vomiting and diarrhea
stimulation of muscarinic
receptors include all of the 172. Which of those drugs used for
following EXCEPT: acute toxic effects of
a) Abdominal cramps, diarrhea organophosphate cholinesterase
b) Increased salivation, excessive inhibitors?
bronchial secretion a) Atropine
c) Miosis, bradycardia b) Pilocarpine
d) Weakness of all skeletal c) Pralidoxime
muscles d) Edrophonium
 

173. The group of nicotinic 178. Indicate the skeletal muscle


receptor-blocking drugs consists relaxant, which is a depolarizing
of: agent:
1. Ganglion-blockers a) Vencuronium
2. Atropine-similar drugs b) Scopolamine
3. Neuromuscular junction blockers c) Succinylcholine
4. Both a and c d) Hexamethonium

174. M3 receptor subtype is located: 179. Which of the following drugs


1. In the myocardium is a nondepolarizing muscle
2. In sympathetic postganglionic relaxant?
neurons a) Pancuronium
3. On effector cell membranes of b) Succinylcholine
glandular and smooth muscle cells c) Hexamethonium
4. On the motor end plates d) Scopolamine

175. Which of the following drugs 180. Indicate the drug, which is
is both a muscarinic and nicotinic rapidly and fully distributed into
blocker? CNS and has a greater effect than
a) Atropine most other antimuscarinic
b) Benztropine agents?
c) Hexamethonium a) Atropine
d) Succinylcholine b) Scopolamine
c) Homatropine
176. Indicate a muscarinic d) Ipratropium
receptor-blocking drug:
a) Scopolamine 181. The effect of the drug on
b) Pipecuronium parasympathetic function
c) Trimethaphan declines rapidly in all organs
d) Pilocarpine EXCEPT:
a) Eye
177. Which of the following agents b) Heart
is a ganglion-blocking drug? c) Smooth muscle organs
a) Homatropine d) Glands
b) Hexamethonium
c) Rapacuronium
d) Edrophonium
 

182. The mechanism of atropine 186. Atropine causes:


action is: a) Miosis, a reduction in intraocular
a) Competitive ganglion blockade pressure and cyclospasm
b) Competitive muscarinic b) Mydriasis, a rise in intraocular
blockade pressure and cycloplegia
c) Competitive neuromuscular c) Miosis, a rise in intraocular
blockade pressure and cycloplegia
d) Noncompetitive d) Mydriasis, a rise in intraocular
neuromuscular blockade pressure and cyclospasm

183. The tissues most sensitive to 187. Patients complain of dry or


atropine are: “sandy” eyes when receiving large
1. The salivary, bronchial and doses of:
sweat glands a) Atropine
2. The gastric parietal cells b) Hexamethonium
3. Smooth muscle and autonomic c) Pilocarpine
effectors d) Carbachol
4. The heart
188. All of the following parts of the
184. Atropine is highly selective heart are very sensitive to
for: muscarinic receptor blockade
a) M1 receptor subtype except:
b) M2 receptor subtype a) Atria
c) M3 receptor subtype b) Sinoatrial node
d) All of the above c) Atrioventricular node
d) Ventricle
185. Which of the following
antimuscarinic drugs is often 189. Atropine causes:
effective in preventing or a) Bradycardia, hypotension and
reversing vestibular disturbances, bronchoconstriction
especially motion sickness? b) Tachycardia, little effect on blood
a) Atropine pressure and bronchodilation
b) Ipratropium c) Decrease in contractile strength,
c) Scopolamine conduction velocity through the
d) Homatropine AV node
d) Tachycardia, hypertensive crisis
and bronchodilation
 

190. Atropine is frequently used 194. Which of the following drugs


prior to administration of is useful in the treatment of
inhalant anesthetics to reduce: uterine spasms?
a) Muscle tone a) Carbachol
b) Secretions b) Vecuronium
c) Nausea and vomiting c) Atropine
d) All of the above d) Edrophonium

191. Atropine is now rarely used 195. Atropine may cause a rise in
for the treatment of peptic ulcer body temperature (atropine
because of: fever):
a) Slow gastric empting and a) In adults
prolongation of the exposure b) In pregnant women
of the ulcer bed to acid c) In infants and children
b) Low efficiency and necessity d) All of the above
of large doses
c) Adverse effects 196. The pharmacologic actions of
d) All of the above scopolamine most closely
resemble those of:
192. Which of the following a) Hexamethonium
antimuscarinic drugs is a b) Atropine
selective M1 blocker? c) Succinylcholine
a) Atropine d) Pilocarpine
b) Scopolamine
c) Pirenzepine 197. Compared with atropine,
d) Homatropine scopolamine has all of the
following properties EXCEPT:
193. Atropine causes: a) More marked central effect
a) Spasmolitic activity b) Less potent in decreasing
b) Intestinal hypermotility bronchial, salivary and
c) Stimulation of contraction in sweat gland secretion
the gut c) More potent in producing
d) Stimulation of secretory mydriasis and cycloplegia
activity d) Lower effects on the heart,
bronchial muscle and
intestines
 

198. Indicate the antimuscarinic 202. Antimuscarinics are used in


drug, which is used as a the treatment of the following
mydriatic: disorders EXCEPT:
a) Pilocarpine a) Motion sickness
b) Neostigmine b) Glaucoma
c) Homatropine c) Hyperhidrosis
d) Ipratropium d) Asthma

199. Which of the following agents 203. The atropine poisoning


is used as an inhalation drug in includes all of the following
asthma? symptoms EXCEPT:
a) Atropine a) Mydriasis, cycloplegia
b) Ipratropium b) Hyperthermia, dry mouth, hot
c) Lobeline and flushed skin
d) Homatropine c) Agitation and delirium
d) Bradicardia, orthostatic
200. Which of the following agents hypotension
is most effective in regenerating
cholinesterase associated with 204. The treatment of the
skeletal muscle neuromuscular antimuscarinic effects can be
junctions? carried out with:
a) Suscinilcholine a) Neostigmine
b) Pralidoxime b) Hexametonium
c) Pirenzepine c) Homatropine
d) Propiverine d) Acetylcholine

201. Indicate an antimuscarinic 205. Contraindications to the use of


drug, which is effective in the antimuscarinic drugs are all of
treatment of mushroom poising: the following except:
a) Pralidoxime a) Glaucoma
b) Pilocarpine b) Myasthenia
c) Homatropine c) Bronchial asthma
d) Atropine d) Paralytic ileus and atony of
the urinary bladder
 

206. Hexamethonium blocks the 210. Skeletal muscle relaxation and


action of acethylcholine and paralysis can occur from
similar agonists at: interruption of functions at
a) Muscarinic receptor site several sites, including all of the
b) Neuromuscular junction following EXCEPT:
c) Autonomic ganglia a) Nicotinic acethylcholine
d) Axonal transmission receptors
b) Muscarinic acethylcholine
207. Which of the following agents receptors
is a short-acting ganglion c) The motor end plate
blocker? d) Contractile apparatus
a) Homatropine
b) Trimethaphane 211. Nondepolarisation
c) Hexamethonium neuromuscular blocking agents:
d) Pancuronium a) Block acetylcholine reuptake
b) Prevent access of the
208. Ganglion blocking drugs are transmitter to its receptor and
used for the following depolarization
emergencies EXCEPT: c) Block transmission by an
a) Hypertensive crises excess of a depolarizing
b) Controlled hypotension agonist
c) Cardiovascular collapse d) All of the above
d) Pulmonary edema
212. Which of the following drugs
209. Agents that produce has “double-acetylcholine”
neuromuscular blockade act by structure?
inhibiting: a) Rocuronium
a) Interaction of acetylcholine b) Carbachol
with cholinergic receptors c) Atracurium
b) Release of acetylcholine from d) Succylcholine
prejunctional membrane
c) Packaging of acetylcholine 213. Indicate the long-acting
into synaptic vesicles neuromuscular blocking agent:
d) Reuptake of acetylcholine into a) Rapacuronium
the nerve ending b) Mivacurium
c) Tubocurarine
d) Rocuronium
 

214. Which of the following d) Cholinesterase inhibitors do not


neuromuscular blocking drugs is have the ability to reverse the
an intermediate-duration muscle blockade
relaxant?
a) Vecuronium 218. Which of the following
b) Tubocurarine neuromuscular blockers causes
c) Pancuronium transient muscle fasciculations?
d) Rapacuronium a) Mivacurium
b) Pancuronium
215. Which competitive c) Succinylcholine
neuromuscular blocking agent d) Tubocurarine
could be used in patients with
renal failure? 219. Which neuromuscular
a) Atracurium blocking agent has the potential
b) Succinylcholine to cause the greatest release of
c) Pipecuronium histamine?
d) Doxacurium a) Succylcholine
b) Tubocurarine
216. Which depolarizing agent has c) Pancuronium
the extremely brief duration of d) Rocuronium
action?
a) Mivacurium 220. Indicate the neuromuscular
b) Rapacuronium blocker, which causes
c) Rocuronium tachycardia:
d) Succinylcholine a) Tubocurarine
b) Atracurium
217. Depolarizing agents include all c) Pancuronium
of the following properties d) Succinylcholine
EXCEPT:
a) Interact with nicotinic receptor to 221. Which neuromuscular
compete with acetylcholine blocking agent is contraindicated
without receptor activation in patients with glaucoma?
b) React with the nicotinic receptor a) Tubocurarine
to open the channel and cause b) Succinylcholine
depolarisation of the end plate c) Pancuronium
c) Cause desensitization, d) Gallamine
noncompetive block manifested
by flaccid paralysis
 

222. All of the following drugs 2. Select the narcotic analgesic,


increase the effects of which is an antagonist or
depolarizing neuromuscular partial mu receptor agonist:
blocking agents EXCEPT: a) Fentanyl
a) Aminoglycosides b) Pentazocine
b) Antiarrhythmic drugs c) Codeine
c) Nondepolarizing blockers d) Methadone
d) Local anesthetics
3. Which of the following agents
223. Which of the following is a full antagonist of opioid
diseases can augment the receptors?
neuromuscular blockade a) Meperidine
produced by nondepolarizing b) Buprenorphine
muscle relaxants? c) Naloxone
a) Myasthenia gravis d) Butorphanol
b) Burns
c) Asthma 4. The principal central nervous
d) Parkinsonism system effect of the opioid
analgesics with affinity for a
224. Indicate the agent, which mu receptor is:
effectively antagonizes the a) Analgesia
neuromuscular blockade caused b) Respiratory depression
by nondepolarizing drugs: c) Euphoria
a) Atropine d) All of the above
b) Neostigmine
c) Acetylcholine 5. Most strong mu receptor
d) Pralidoxime agonists cause:
a) Hypertension
2. Analgesia: b) Increasing the
pulmonary arterial
pressure and
1. Indicate the narcotic analgesic,
myocardial work
which is a natural agonist:
c) Cerebral vasodilatation,
a) Meperidine
causing an increase in
b) Fentanyl
intracranial pressure
c) Morphine
d) All of the above
d) Naloxone
 

6. Morphine causes the following c) Fentanyl


effects EXCEPT: d) Loperamide
a) Constipation
b) Dilatation of the biliary duct 11. The diagnostic triad of opioid
c) Urinary retention overdosage is:
d) Bronchiolar constriction a) Mydriasis, coma and
hyperventilation
7. Therapeutic doses of the opioid b) Coma, depressed respiration
analgesics: and miosis
a) Decrease body temperature c) Mydriasis, chills and
b) Increase body temperature abdominal cramps
c) Decrease body heat loss d) Miosis, tremor and vomiting
d) Do not affect body
temperature 12. Which of the following opioid
agents is used in the treatment
8. Which of the following opioid of acute opioid overdose?
analgesics is used in obstetric a) Pentazocine
labor? b) Methadone
a) Fentanyl c) Naloxone
b) Pentazocine d) Remifentanyl
c) Meperidine
d) Buprenorphine
13. Non-narcotic analgesics are
mainly effective against pain
9. Indicate the opioid analgesic,
associated with:
which is used for relieving the
a) Inflammation or tissue
acute, severe pain of renal
damage
colic:
b) Trauma
a) Morphine
c) Myocardial infarction
b) Naloxone
d) Surgery
c) Methadone
d) Meperidine
14. Non-narcotic agents cause:
a) Respiratory depression
10. Which of the following opioid
b) Antipyretic effect
analgesics is used in the
c) Euphoria
treatment of acute pulmonary
d) Physical dependence
edema?
a) Morphine
b) Codeine
 

15. Which of the following non- 19. Correct statements concerning


narcotic agents is salicylic acid aspirin include all of the
derivative? following EXCEPT:
a) Phenylbutazone a) It inhibits mainly
b) Ketamine peripheral COX
c) Aspirin b) It does not have an
d) Tramadol anti-inflammatory
effect
16. Which one of the following c) It inhibits platelet
non-narcotic agents inhibits aggregation
mainly cyclooxygenase (COX) d) It stimulates respiration
in CNS? by a direct action on
a) Paracetamol the respiratory center
b) Ketorolac
c) Acetylsalicylic acid 20. For which of the following
d) Ibuprofen conditions could aspirin be
used prophylactically?
17. Most of non-narcotic a) Noncardiogenic
analgetics have: pulmonary edema
a) Anti-inflammatory b) Peptic ulcers
effect c) Thromboembolism
b) Analgesic effect d) Metabolic acidosis
c) Antipyretic effect
d) All of the above 21. All of the following are
undesirable effects of aspirin
18. Indicate the non-narcotic EXCEPT:
analgesic, which lacks an anti- a) Gastritis with focal
inflammatory effect: erosions
a) Naloxone b) Tolerance and physical
b) Paracetamol addiction
c) Metamizole c) Bleeding due to a
d) Aspirin decrease of platelet
aggregation
d) Reversible renal
insufficiency
 

22. Characteristic findinds of 26. Descriptive of the drug that


salicylism include: may have an agonist effect at
a) Headache, mental one opioid receptor site and an
confusion and antagonist effect at another
drowsiness opioid receptor site.
b) Tinnitus and difficulty a) full agonist
in hearing b) pure antagonist
c) Hyperthermia, c) mixed agonist-antagonist
sweating, thirst, d) endorphin
hyperventilation, e) Dynorphins
vomiting and diarrhea
d) All of the above 27. Principal alkaloid in opium
(derived from opium poppy)
23. Narcotic agonists: most serious a) morphine
adverse effect: b) fentanyl (Sublimaze)
a) cardiac arrhythmias c) codeine
b) respiratory depression d) naloxone (Narcan)
c) convulsions e) meperidine (Demerol)
d) endogenous depression
24. Physiological effects of 28. Opioid effect least likely to
morphine: exhibit tolerance following
a) chronic diahrrea prolonged opioid
b) mydriasis administration:
c) respiratory depression a) analgesia
d) A & C b) bradycardia
c) respiratory depression
25. An opioid with both agonist d) Miosis
and antagonist properties: e) Euphoria
a) morphine
b) meperidine (Demerol) 29. Opioid antagonist with
c) pentazocine (Talwain) shortest duration of action:
d) oxycodone (Roxicodone) a) naloxone (Narcan)
b) nalmefene (Revex)
c) naltrexone (ReVia)
d) all about equal duration of
action
 

e) these agents are not opioid 3. Anaesthesia:


antagonists

1. The state of “general


30. Contraindications/caution for
anesthesia” usually includes:
opioid use:
a. Analgesia
a) patients with Addison's
b. Loss of consciousness,
disease
inhibition of sensory and
b) patients with impaired
autonomic reflexes
pulmonary function
c. Amnesia
c) patients with head injury
d. All of the above
d) B&C
e) A, B & C
2. Inhaled anesthetics and
intravenous agents having
31. Signs and symptoms of acute
general anesthetic properties:
opioid withdrawal (abstinence
a. Directly activate GABAA
syndrome)
receptors
a) yawning
b. Facilitate GABA action but
b) lacrimation
have no direct action on
c) hyperventilation
GABAA receptors
d) diarrhea
c. Reduce the excitatory
e) all the above
glutamatergic
neurotransmission
32. In obstetrical
d. Increase the duration of
applications:opioid less likely
opening of nicotine-activated
to produce respiratory
potassium channels
depression in the newborn
a) meperidine (Demerol)
3. An ideal anesthetic drug
b) morphine
would:
a. Induces anesthesia smoothly
and rapidly and secure rapid
recovery
b. Posses a wide margin of safety
c. Be devoid of adverse effects
d. All of the above
 

4. Which of the following 9. Which of the following


general anesthetics belongs to inhaled anesthetics is an
inhalants? induction agent of choice in
a. Thiopental patient with airway problems?
b. Desfluran a. Desfurane
c. Ketamine b. Nitrous oxide
d. Propofol c. Halothane
d. None of the above
5. Indicate the anesthetic, which
is used intravenously: 10. Indicate the inhaled anesthetic,
a. Propofol which causes the airway
b. Halothane irritation:
c. Desflurane a. Nitrous oxide
d. Nitrous oxide b. Sevoflurane
c. Halothane
6. Which of the following d. Desflurane
inhalants is a gas anesthetic?
a. Halothane 11. Which of the following
b. Isoflurane inhaled anesthetics can
c. Nitrous oxide produce hepatic necrosis?
d. Desflurane a. Soveflurane
b. Desflurane
7. Which of the following c. Halothane
inhaled anesthetics has rapid d. Nitrous oxide
onset and recovery?
a. Nitrous oxide 12. Unlike inhaled anesthetics,
b. Desflurane intravenous agents such as
c. Sevoflurane thiopental, etomidate, and
d. All of the above propofol:
a. Have a faster onset and rate of
8. Indicate the inhaled anesthetic, recovery
which reduces arterial b. Provide a state of conscious
pressure and heart rate: sedation
a. Isoflurane c. Are commonly used for
b. Halothane induction of anesthesia
c. Desflurane d. All of the above
d. Nitrous oxide
 

13. Indicate the intravenous 17. Local anesthetics types: shorter


anesthetic, which is an ultra- duration of action
short-acting barbiturate: a. Ester-type agents
a. Fentanyl b. Amide-type agents
b. Thiopental c. no difference in
c. Midazolam duration of action
d. Ketamine
18. Factors influencing local
14. Which of the following anesthetic absorption and
intravenous anesthetics has distribution:
antiemetic actions? a. presence of
a. Thiopental vasoconstrictors
b. Propofol b. injection site
c. Ketamine c. dosage
d. Fentanyl d. A&C
e. A, B & C
15. Indicate the intravenous
anesthetic, which produces 19. Addition to vasoconstrictors
dissociative anesthesia: may prolong/enhance spinal
a. Midazolam anesthesia by:
b. Ketamine a. activating alpha2 adrenergic
c. Fentanyl receptors
d. Thiopental b. increase local neuronal local
anesthetic uptake
16. Ketamine anesthesia is c. both
associated with: d. neither
a. Cardiovascular stimulation
b. Increased cerebral blood flow, 20. Effect of clonidine (Catapres)
oxygen consumption and addition to local anesthetic
intracranial pressure solutions:
c. Disorientation, sensory and a. enhanced local anesthetic
perceptual illusions, and vivid effectiveness
dreams following anesthesia b. reduced local anesthetic
d. All of the above effectiveness
c. no clonidine (Catapres)
influence on local anesthetic
efficacy
 

21. Effect of local anesthetic- 25. Local anesthetics: acid/base


mediated vasodilation on properties
pharmacokinetic a. Local anesthetics are weak
characteristics: acids
a. Greater vasodilation -- b. Local anesthetics are weak
longer duration of action; bases
reduced systemic absorption c. Local anesthetics have no
b. Greater vasodilation -- ionizable groups
increased systemic absorption;
reduced duration of action 26. Factors influencing
effectiveness of epinephrine or
22. Pharmacokinetic characteristic local anesthesia:
of local anesthetics which a. choice of local anesthesia
favor more rapid onset of b. level of sensory blockade
action: required or spinal anesthesia
a. pK farther away from c. both
physiological pH d. neither
b. pK close to physiological
pH 27. Example(s) of ester-type local
anesthetics:
23. Type of local anesthetic with a. procaine (Novocain)
wider distribution: b. tetracaine (pontocaine)
a. Amide agents c. cocaine
b. Ester agents d. A&C
c. no difference e. A, B & C

24. pKa range for most local 28. Clearance: amide local
anesthetics anesthetic
a. 6.0-7.0 a. rapid hydrolysis
b. 7.0-8.0 b. hepatic mediation
c. 8.0-9.0 c. significant renal excretion
d. > 9.0
 

29. Patient presentations which is a. Allergic reactions


suggestive of local anesthetic b. Systemic toxicity
allergy: c. both
a. rash d. neither
b. urticaria
c. laryngeal edema 32. Factor(s) which influence the
d. bronchospasm extent of local anesthetic
e. all the above systemic absorption
a. initial dose administered
30. Basis/evidence for local b. injection site vascularity
anesthetic allergies: c. whether or not epinephrine
a. clinical history was used to provide local
b. intradermal testing vasoconstriction
c. both d. properties of the drug itself
d. neither e. all the above

31. Primary side effect(s) of local


anesthetics:
 

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