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MCQs on Vitamins
By:Dr Sara ali Shoaib
‫ﺩ ﺳﺎﺭﺓ ﻋﻠﻲ ﺷﻌﻴﺐ‬
2013-2014
Benghazi University Faculty
Of Medicine
Biochemistry Department

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-Essential For The Process Of Nerve Conduction And Structure Of Nerve

Membrane
• (B1) Thiamine
• vitamin B12
• Biotin B7
• Vitamin B6

-Wernicke-Korsakoff syndrome seen in deficiency of

• (B1) Thiamine
• vitamin B12
• Biotin B7
• Vitamin B6

-Affects the heart it is sometimes fatal, as it causes a combination of heart

failure and weakening of the capillary walls
• Wet Beriberi
• Pellagra
• Dry beriberi

-Found in Milk , Milk Products ,Eggs, Liver And Green Leafy Vegetables
• B2 (Riboflavin)
• vitamin B12
• Biotin B7
• Vitamin B6

-Cheilosis due to deficiency of :

• B2 (Riboflavin)
• vitamin B12
• Biotin B7
• Vitamin B6

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-Enters in the formation of coenzyme Nicotinamide Adenine Dinucleotide

(NAD) :
• B3
• vitamin B12
• Biotin B7
• Vitamin B6

-Pellagra
Deficiency of niacin

-Biotin acts as coenzyme for:

• Carboxylase
• Decaboxylase
• Oxidase
• lipase

-Gastric Intrinsic Factor (GIF) is:

• a glycoprotein produced by the parietal cells of the stomach
• a lipoprotein produced by liver

-Deficiency of folic acid:

• Megaloblastic Anemia
• Wet Beriberi
• Pellagra
• Dry beriberi

-Vitamins are
• Accessory food factors
• Generally synthesized in the body
• Produced in endocrine glands
• Proteins in nature

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-Preformed Vitamin A is supplied by

• Milk, fat and liver
• All yellow vegetables
• All yellow fruits
• Leafy green vegetables

-Fat soluble vitamins are

• Soluble in alcohol
• one or more Propene units
• Stored in liver
• All these

-One manifestation of vitamin A deficiency

• Painful joints
• Night blindness
• Loss of hair
• Thickening of long bones

-Deficiency of Vitamin A causes

• Xeropthalmia
• Hypoprothrombinemia
• Megaloblastic anemia
• Pernicious anemia

- An important function of vitamin A is

• To act as coenzyme for a few enzymes
• To play an integral role in protein synthesis
• To prevent hemorrhages
• To maintain the integrity of epithelial tissue

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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- Retinal is a component of
• Iodopsin
• Rhodopsin
• Cardiolipin
• Glycoproteins

-Retinoic acid participates in the synthesis of

• Iodopsin
• Rhodopsin
• Glycoprotein
• Cardiolipin

-Vitamin D absorption is increased in

• Acid pH of intestine
• Alkaline pH of intestine
• Impaired fat absorption
• Contents of diet

-The most potent Vitamin D metabolite is

• 25-Hydroxycholecalciferol
• 1,25-Dihydroxycholecalciferol
• 24, 25-Dihydroxycholecalciferol
• 7-Dehydrocholesterol

- A poor source of Vitamin D is

• Egg
• Butter
• Milk
• D) Liver

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-Richest source of Vitamin D is

• Fish liver oils
• Margarine
• Egg yolk
• Butter

-Deficiency of vitamin D causes

• Ricket and osteomalacia
• Tuberculosis of bone
• Hypthyroidism
• Skin cancer

-Calcitriol synthesis involves

• Both liver and kidney
• Intestine
• Adipose tissue
• Muscle

-Vitamin E reduces the requirement of

• Iron
• Zinc
• Selenium
• Magnesium
•
-The most important natural antioxidant is
• Vitamin D
• Vitamin E
• Vitamin B12
• Vitamin K

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-The vitamin required for the formation of hydroxyproline (in collagen) is

• Vitamin C
• Vitamin A
• Vitamin D
• Vitamin E

-Scurvy is caused due to the deficiency of

• Vitamin A
• Vitamin D
• Vitamin K
• Vitamin C

-Both Wernicke’s disease and beriberi can be reversed by administrating

• Retinol
• Thiamin
• Pyridoxine
• Vitamin B12

-The Vitamin B1 deficiency causes

• Ricket
• Nyctalopia
• Beriberi
• Pellagra

- Concentration of pyruvic acid and lactic acid in blood is increased due to

deficiency of the vitamin
• Thiamin
• Riboflavin
• Niacin
• Pantothenic acid
•

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-Vitamin B1coenzyme (TPP) is involved in

• Oxidative decarboxylation
• Hydroxylation
• Transamination
• Carboxylation

-Increased glucose consumption increases the dietary requirement for

• Pyridoxine
• Niacin
• Biotin
• Thiamin

- Thiamin is oxidized to thiochrome in alkaline solution by

• Potassium permanganate
• Potassium ferricyanide
• Potassium chlorate
• Potassium dichromate

- Riboflavin is a coenzyme in the reaction catalysed by the enzyme

• Acyl CoA synthetase
• Acyl CoA dehydrogenase
• β-Hydroxy acyl CoA
• Enoyl CoA dehydrogenase

- The daily requirement of riboflavin for adult in mg is

• 0–1.0
• 1.2–1.7
• 2.0–3.5
• 4.0–8.0

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-In new born infants phototherapy may cause hyperbilirubinemia with deficiency
of
• Thiamin
• Riboflavin
• Ascorbic acid
• Pantothenic acid

-Riboflavin deficiency causes

• Cheilosis
• Loss of weight
• Mental deterioration
• Dermatitis

-The pellagra preventive factor is

• Riboflavin
• Pantothenic acid
• Niacin
• Pyridoxine

-Pellagra is caused due to the deficiency of

• Ascorbic acid
• Pantothenic acid
• Pyridoxine
• Niacin

Niacin or nicotinic acid is a monocarboxylic acid derivative of

• Pyridine
• Pyrimidine
• Flavin
• Adenine

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-Niacin is synthesized in the body from

• Tryptophan
• Tyrosine
• Glutamate
• Aspartate

-The proteins present in maize are deficient in

• Lysine
• Threonine
• Tryptophan
• Tyrosine

-Niacin is present in maize in the form of

• Niatin
• Nicotin
• Niacytin
• Nicyn

-Pellagra occurs in population dependent on

• Wheat
• Rice
• Maize
• Milk

-The enzymes with which nicotinamide act as coenzyme are

• Dehydrogenases
• Transaminases
• Decarboxylases
• Carboxylases

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-Dietary requirement of Vitamin D:

• 400 I.U.
• 1000 I.U.
• 6000 I.U.
• 700 I.U.

-The Vitamin which does not contain a ring in the structure is

• Pantothenic acid
• Vitamin D
• Riboflavin
• Thiamin

-Pantothenic acid is a constituent of the coenzyme involved in

• Decarboxylation
• Dehydrogenation
• Acetylation
• Oxidation

-The precursor of CoA is

• Riboflavin
• Pyridoxamine
• Thiamin
• Pantothenate

Burning foot syndrome’ has been ascribed to the deficiency of

• Pantothenic acid
• Thiamin
• Cobalamin
• (D) Pyridoxine

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-Pyridoxal phosphate is central to

• Deamination
• Amidation
• Carboxylation
• Transamination

- The vitamin required as coenzyme for the action of transaminases is

• Niacin
• Pantothenic acid
• (C) Pyridoxal phosphate
• (D) Riboflavin

-Vitamin B6 deficiency may occur during therapy with

• Isoniazid
• Terramycin
• Sulpha drug
• Aspirin

-Vitamin B6 deficiency may occur during therapy with

• Isoniazid
• Terramycin
• Sulpha drugs
• Aspirin

-Biotin is a coenzyme of the enzyme

• Carboxylase
• Hydroxylase
• Decarboxylase
• Deaminase

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-The coenzyme required for conversion of pyruvate to oxaloacetate is

• FAD
• NAD
• TPP
• Biotin

-Consumption of raw eggs can cause deficiency of

• Biotin
• Pantothenic acid
• Riboflavin
• Thiamin

-The cofactor or its derivative required for the conversion of acetyl CoA to
malonylCoA is
• FAD
• ACP
• NAD
• Biotin

-A cofactor required in oxidative decarboxylation of pyruvate is

• Lipoate
• Pantothenic acid
• Biotin
• Para aminobenzoic acid

-The central structure of B12 referred to as corrin ring system consists of

• Cobalt
• Manganese
• Magnesium
• Iron

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-The central heavy metal cobalt of vitamin B12is coordinately bound to

• Cyanide group
• Amino group
• Carboxyl group
• Sulphide group

-Vitamin B12has a complex ring structure (corrin ring) consisting of four

• Purine rings
• Pyrimidine rings
• Pyrrole rings
• Pteridine rings

- A deficiency of vitamin B12 causes

• Beri-Beri
• Scurvy
• Perniciuos anemia
• Ricket

-Vitamin B12deficiency can be diagnosed by urinary excretion of

• Pyruvate
• Methylmalonate
• Malate
• Lactate

-Subacute combined degeneration of cord is caused due to deficiency of

• Niacin
• Cobalamin
• Biotin
• Thiamin

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-Vitamin required for metabolism of diols e.g. conversion of ethylene glycol to

acetaldehyde is
• Thiamin
• Cobalamin
• Pyridoxine
• Folic acid

-Both folic acid and methyl cobalamin (vitamin B 12) are required in
• Deamination of serine
• Deamination of threonine
• Conversion of pyridoxal phosphate to pyridoxamine phosphate
• Methylation of homocystein to methionine

-Folic acid or folate consists of the

• Base pteridine, p-amino benzoic acid and asparate
• Base purine, p-amino benzoic acid and glutamate
• Base pteridine, p-amino benzoic acid and glutamate
• Base purine, p-hydroxy benzoic acid and glutamate

-Folate as a coenzyme is involved in the transfer and utilization of

• Amino group
• Hydroxyl group
• Single carbon moiety
• Amido group

-Folic acid deficiency can be diagnosed by increased urinary excretion of

• Methylmalonate
• Figlu
• Cystathionine
• Creatinine

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-Sulpha drugs interfere with bacterial synthesis of

• Lipoate
• Vitamin E
• Tetrahydrofolate
• Ascorbic acid

-Folate deficiency causes

• Microcytic anemia
• Hemolytic anemia
• Iron deficiency anemia
• Megaloblastic anemia

-Thiamin deficiency includes

• Mental depression
• Fatigue
• Beriberi
• All of these

-Thiamin diphosphate is required for oxidative decarboxylation of

• α-Keto acids
• α-Amino acids
• Fatty acids
• All of these

- Loss of thiamin can be decreased by using

• Unpolished rice
• Parboiled rice
• Whole wheat flour
• All of these

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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-Thiamin requirement is greater in

• Non-vegetarians
• Alcoholics
• Pregnant women
• Both B and C

-People consuming polished rice as their staple food are prone to

• Beriberi
• Pellagra
• Both (A) and (B)
• None of these

-Riboflavin is heat stable in

• Acidic medium
• Alkaline medium
• Neutral medium
• Both (A) and (C)

-FAD is a coenzyme for

• Succinate dehydrogenase
• Glycerol-3-phosphate dehydrogenase
• Sphingosine reductase
• All of these

-Riboflavin deficiency can cause

(A) Peripheral neuritis
(B) Diarrhoea
(C) Angular stomatitis
(D) None of these

-Pellagra preventing factor is:

By Dr.sara ali shoaib
‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬
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(A) Thiamin
(B) Riboflavin
(C) Niacin
(D) Pyridoxine

By Dr.sara ali shoaib

‫د ﺳﺎرﻩ ﻋﻠﻲ ﺷﻌﺒﺐ‬