DRUG ACTION INDICATION CONTRAINDICATI ADVERSE NURSING

ON EFFECTS CONSIDERATIONS

Nicardipine Inhibits calcium ion Management of: Patients who do not Peripheral edema, > Assess patient before
influx across cell hypertension, have complete headache, and after giving the drug.
membrane during angina pectoris, hemostasis tachycardia, > Monitor vital signs.
cardiac vasospastic angina. following palpitations, > PO route: Do not open,
depolarization, Unlabeled use: intracranial localized crush, chew sustained
produces relaxation Management of hemorrhage. thrombophlebitis release capsule.
of coronary vascular congestive heart Increased and hypotension. > IV route: Dilute each
smooth muscle, failure. intracranial 25mg/240ml of
dilates coronary pressure during compatible solution. Give
arteries, and acute phase of slowly.
increases stroke. > Give with or without
myocardial delivery regards to meals.
in patients with > Store in airtight
vasospastic angina. container at room
temperature.
> Health Education:
- Take with non-fatty food.
- Avoid caffeine and
alcohol.
- Consult physician before
increasing exercise
routine.
- Report possible adverse
side effects immediately.

Esmolol Competitively Short-term Sinus bradycardia, Symptomatic and > Assess patient before
blocks stimulation management of heartblock >1st asymptomatic and after giving the drug.
of alpha 1- supraventricular degree, cardiogenic hypotension, > Assess patient and
adrenergic tachyarrhythmias shock or overt heart diaphoresis family’s knowledge of
receptors in the and failure. Patients who accompanied drug therapy.
myocardium noncompensatory require inotropic hypotension, > Monitor vital signs.
resulting to sinus tachycardia. agents dizziness, > Give by intermittent
negative and/orvasopressors somnolence, infusion after diluting with
chronotrophic and to maintain confusion, compatible solution.
inotrophic activity: systemic blood bronchospasm, > Give overloading dose
decrease rate of SA pressure and wheezing, GI for 1min, then
node discharge, cardiac output. IV disturbances, maintenance dose for
 slow conduction of cavcium channel inflammation and 4mins.
AV node, decrease antagonists, IV induration of > Health Education:
heart rate and verapamil or within infusion site. - Caution patient to rise
oxygen close proximity. slowly to prevent
consumption of the orthostatic hypotension.
myocardium. It also - Report possible adverse
decreases rennin- side effects immediately.
angiotensin-
aldosterone system
at high doses and
inhibits alpha 2-
receptors in
bronchial system at
higher doses.

Insulin Decreases blood Management of Hypoglycemia, Redness, pain, > Assess patient before
glucose; by type 1 DM or insulin insulinomia, itching, hives, and after giving the drug.
transport of glucose dependent DM and hypersensitivity swelling or > Monitor vital signs.
into cells and the type 2 DM or reactions. IV inflammation. >FOR SUBQ ROUTE
conversion of noninsulin administration of Hypoglycemia, - Give after warming to
glucose to glycogen dependent DM insulin suspension, temporary visual room temp by rotating
indirectly increases which cannot be diabetic coma. impairment. Edema palm.
blood pyruvate and controlled by diet, and referction - Rotate sites.
lactate, decreases exercise or weight anomalies. - Give lispro 15mins
phosphate and reduction alone. before meals.
potassium. - Keep away from heat
and sunlight.
> FOR IV ROUTE, regular
only
- Do not use if cloudy,
thick or discolored.
- Give at 50U/min or less.
>Health Education:
- Instruct patient on
proper technique for
administration.
- Discuss importance of
not changing brands.
- Advise not to exercise
and not to smoke 30mins
 after administration of
insulin.
- Notify physician if
pregnant or planning to
be pregnant.
- Inform patient with the
importance of diet and
exercise.
- Advise to carry medical
identification at all time.

Stephanie Claire C. Paulino

BSN 4Y1-3
Group 313B