2. A Guyton Med Physio 11th ed pg 480 3. D Harrison’s 20th Ed pg 296 4. A Ophtha Secrets 4th Ed 2016 pg 52 5. A Lippincot Pharma 6th Ed pg 242 6. A Harrison’s pgs 1781 and 3246 7. A Guyton Med Physio 11th Ed. Pg 947 8. C Guyton Med Physio 11th Ed. Pg 974 9. D Guyton Med Physio 11th Ed. Pg 473 10. B Guyton Med Physio 11th Ed. Pg. 776 11. C Harrison’s 20th Edition Pg. 2113 12. D Guyton Med Physio 11th Ed. Pg 1007 13. A Guyton Med Physio 11th Ed. Pg. 797 14. C Harrison’s 20th Edition Pg 2604 15. C Guyton Med Physio 11th Ed. Pg 347 16. D Guyton Med Physio 11th Ed. Pg 1055 17. A Harrison’s 20th Edition Pg. 2510 18. D Harrison’s 20th Edition Pg. 711 19. D Harrison’s 20th Edition Pg. 3335 20. C Harrison’s 20th Edition Pg. 3333 21. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 330 22. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 532 23. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 390 24. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 1030 25. B. Seeley’s Essentials of Anatomy and Physiology 9th ed., p. 502 26. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 927 27. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 563 28. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 79 29. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 541 30. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 748 31. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 949 32. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 3031 33. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 114 34. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 536 35. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 501 36. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 184 37. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 501 38. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 124 39. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 473 40. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 1048 41. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 841 42. A. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 88 43. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 535 44. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 2018 45. A. BRS Physiology 5th ed., p. 168 46. A. Harrisons Principles of Internal Medicine 20th ed., p. 2053 47. A. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 947 48. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 1032 49. A. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 912 50. A. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 959 51. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 455, 459, 465 52. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 587 53. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 834 54. C. BRS Pharmacology 5th ed., p. 13 55. A. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 232 56. A. Harrisons Principles of Internal Medicine 20th ed., p. 259 57. A. BRS Physiology 5th ed., p. 219 58. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 802 59. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 822 60. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 504 61. Neutrophins foster the production of proteins associated with nerve development, growth and survival. Which of the following is CORRECT about nerve growth factor (NGF)? A. It is important for the growth of sensory neurons that supply the muscle spindles B. It is responsible for the growth and maintenance of adrenergic neurons in the brain (Chapter 45: Organization of NS, Basic Functions of Synapses, and Neurotransmitters. p 550, Guyton and Hall 12th ed.) C. It binds to both p75 receptor and Trk A receptors D. It compromises one alpha, two beta and one gamma polypeptide subunits 62. Which of the pancreatic secretion has a receptor with four subunits, two of which have tyrosine kinase activity? A. Glucagon B. Somatostatin C. Pancreatic lipase D. Insulin (Chapter 78: Insulin, Glucagon, and Diabetes Mellitus. p 941, Guyton and Hall 12 th ed.) 63. Total cross sectional area is highest in ______. A. Arterioles B. Capillaries (Unit IV: The Circulation, p 158. Guyton and Hall 12th ed.) C. Veins D. Arteries 64. A defect in the _____ is responsible for the development of some of symptoms of schizophrenia. A. Hypothalamus B. Brain stem C. Mesocortical system D. Limbic system (Unit XI: States of Brain Activity—Sleep, Brain Waves, Epilepsy, Psychoses. p 727, Guyton and Hall 12th ed.) 65. At the muscle end plate Ach causes the opening of ______. A. Sodium channels and depolarization toward the sodium equilibrium potential B. Sodium and potassium channels and hyperpolarization to a value halfway between the Na and K equilibrium potentials C. Sodium and potassium channels depolarization to a value halfway between sodium and potassium equilibrium potentials D. Calcium channels and depolarization toward the calcium equilibrium potential (Unit II: Membrane Physiology, Nerve, and Muscle. p 86, Guyton and Hall 12th ed.) 66. Which of the following is TRUE regarding myogenic type of autoregulation of the kidneys? A. Alteration in GFR is due to glomerular perfusion pressure B. The macula dense senses changes and alter afferent arteriole tone (Chapter 17: Local and Hormonal Control of Tissue Blood Flow. p 195, Guyton and Hall 12th ed.) C. The precise detail of what is sensed in the tubular fluid is still unknown D. An increase in afferent arteriole blood flow would increase glomerular blood flow and increase arteriole wall tension 67. Which is true concerning the physiologic role of oxytocin during normal delivery? A. It stimulates uterine smooth muscle contraction (Chapter 75: Pituitary Hormones and Their Control by the Hypothalamus. p 905, Guyton and Hall 12th ed.) B. It is produced by adenohypophysis C. It decreases uterine contractility D. It inhibits cervical dilatation 68. Which diuretic is administered for the treatment of acute mountain sickness and causes an increase in the pH of urine? A. Chlorothiazide B. Acetazolamide (Comprehensive Examination. p 285, BRS Physiology 5th ed.) C. Spironolactone D. Furosemide 69. Malignant hyperthermia is due to abnormal release of calcium from the sarcoplasmic reticulum and maybe precipitated by _____. I. Certain anesthetic II. High environmental heat III. Lack of exercise A. II & III B. I & III C. I, II, III D. I & II (Chapter 25: Nutrition, Metabolism, and Temperature Regulation. p 957, Seeley’s Essentials of Anatomy and Physiology 8th ed.) 70. Which part of the electrocardiogram corresponds to ventricular repolarization? A. U wave B. T wave (Chapter 11: The Normal ECG. p 122, Guyton and Hall 12th ed.) C. QRS complex D. P wave 71. Which of the following structures contain specialized epithelial cells with multiple foot projections which has phagocytic actions and maintain the basement membrane? A. Tubular basement membrane B. Bowman’s epithelial cells C. Glomerular basement membrane D. Glomerular capillary endothelium (Chapter 26: Urine Formation by the Kidneys I. p 312, Guyton and Hall 12th ed.) 72. Which type of cell protects against sepsis secondary to translocation of intestinal bacteria? A. Cholangiocyte B. Gallbladder epithelial cell C. Kupffer cell (Chapter 70: The Liver as an Organ. p 839, Guyton and Hall 12th ed.) D. Hepatocyte 73. Putamen and anterior horn cells are important in which brain function? A. Language comprehension B. Motor (Chapter 56: Contributions of the Cerebellum and Basal Ganglia to Overall Motor Control. p 690-691, Guyton and Hall 12th ed.) C. Sensory D. Emotion 74. Which can cause metabolic alkalosis? A. Salicylate overdose B. Chronic renal failure C. Diarrhoea D. Hyperaldosteronism (Chapter 30: Acid-Base Regulation. p 393, Guyton and Hall 12th ed.) 75. Non propagated potential depending on their location are called ______. I. Synaptic II. Generator III. Electrotonic A. I, III (Chapter 45: Organization of NS, Basic Functions of Synapses, and Neurotransmitters. p 556, Guyton and Hall 12th ed.) B. II, III C. I, II, III D. I, II 76. Closure of aortic and pulmonic valves produces which sound? A. S4 B. S1 C. S2 (Chapter 9: Cardiac Muscle; The Heart as a Pump and Function of Heart Valves. p 107, Guyton and Hall 12th ed.) D. S3 77. Which is NOT a steroid? A. 17 alpha hydroxyprogesterone B. Estrone C. Pregnenolone D. Relaxin (Chapter 77: Adrenocortical Hormones. p 923, Guyton and Hall 12th ed.) 78. Hypokalemia may cause which of the following ECG changes? I. Prolonged PR interval II. Prominent u wave III. T wave is tall and peaked A. If I, II and III are all correct B. If only I is correct C. If only I and III are correct D. If only II is correct (Chapter 2: ECG. IM Platinum, 3rd ed. p 21.) 79. A disease characterized by muscle weakness is caused by an autoimmune attack against one of the voltage gated Ca channels in the nerve endings of the neuromuscular junction. This is known as _____. A. Guillain Barre syndrome B. Lambert Eaton myesthenic syndrome C. Myasthenia gravis D. Ehlers Danlos syndrome 80. Which step in the steroid hormone synthetic pathway is stimulated by angiotensin II? A. 17, 20 lipase B. 5 alpha reductase C. Aldosterone synthase (Chapter 9: Cardiac Muscle; The Heart as a Pump and Function of Heart Valves. p 107, Guyton and Hall 12th ed.) D. Cholesterol desmolase 80. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 965 81. B. Harrisons Principles of Internal Medicine 20th ed., p. 127 82. A/B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 784 83. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 1022 84. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 650 85. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 893 86. C. Harrisons Principles of Internal Medicine 20th ed., p. 2744 87. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 1044 88. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 954 89. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 919 90. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 17 91. D. Harrisons Principles of Internal Medicine 20th ed., p. 2238 92. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 462 93. C. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 607 94. A. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 1073 95. D. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 802 96. A. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 431 97. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 114 98. C. Keita, Uehara, Tominaga N. and Shibagaki Y. 2014. Adult Orthostatic Proteinuria. Clin Kidney J. 327-328 99. B. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 876 100. A. Guyton and Hall Textbook of Medical Physiology 13th ed., p. 582