Seat No.: _____ Enrolment No.

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GUJARAT TECHNOLOGICAL UNIVERSITY

D.Ph. - Year–2 • EXAMINATION – SUMMER -2018

Subject Code: 420002 Date: 30/04/2018

Subject Name: PHARMACEUTICAL CHEMISTRY-II
Time: 10:30AM TO 01:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Draw structures of following compounds (Any SIX) 06

1. Diazepam 2. Aspirin 3. Atropine 4. Thyroxin
5. Isoprenaline 6. Chlorpheniramine 7. Pethidine 8. Paracetamol
(b) Give a detailed account of Adrenergic drug with example 05
(c) Explain the term Beta blockers, write in detail on Propranolol. 05
Q. 2 (a) Write in detail on Narcotic Analgesics with suitable examples 06
(b) Define Anesthesia, classify Local anaesthetics with examples 05
(c) Give detail account of NSAIDS with suitable examples 05
Q. 3 (a) Classify barbiturates with examples & write in detail on their CNS applications 06
(b) Write in detail on Phenothiazines, draw structure of Chlorpromazine 05
(c) Explain various Benzodiazepines and its applications in mental disorders 05
Q. 4 (a) Classify Antidepressants with examples; write in brief on any one class. 06
(b) Give detail account of CNS stimulants with examples 05
(c) Classify various cardiovascular agents, discuss any one class in detail 05
Q. 5 (a) Write in detail on Beta Lactum antibiotics with suitable examples 06
(b) Discuss various agents from sulphonyl urea class as hypoglycemic agents 05
(c) Classify Diuretics with suitable examples, and discuss its uses. 05
Q. 6 (a) Write a descriptive note on Antimalarial drugs 06
(b) Give chemical classification of antihistaminic with examples 05
(c) Discuss the use of adrenocortical hormones and related compound in medicine 05
Q. 7 (a) Classify vitamins, write a note on water soluble vitamins 06
(b) Write in detail on Antineoplastic agents 05
(c) Explain following terms 05
1. Sedatives 2. Antipyretics 3. Expectorants
4. Arrhythmia 5. Anthelmintics

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