SCIENCE 7 1

PROTEINS AND AMINO ACIDS

At the end of lesson, you should be able to:
 Emphasize the importance of proteins and amino acids

What are amino acids?

Amino acids are special organic molecules used by living organisms to make proteins. The main
elements in amino acids are carbon, hydrogen, oxygen, and nitrogen. There are twenty different
kinds of amino acids that combine to make proteins in our bodies. Our bodies can actually make
some amino acids, but the rest we must get from our food.

What are proteins?

Proteins are long chains of amino acids. There are thousands of different proteins in the human
body. They provide all sorts of functions to help us survive.

Structure of a protein

Why are they important?

Proteins are essential for life. Around 20% of our body is made up of proteins. Every cell in our
body uses proteins to perform functions.

How are they made?

Proteins are made inside cells. When a cell makes a protein it is called protein synthesis. The
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instructions for how to make a protein are held in DNA molecules inside the cell nucleus. The
two major stages in making a protein are called transcription and translation.

Transcription

The first step in making a protein is called transcription. This is when the cell makes a copy (or
"transcript") of the DNA. The copy of DNA is called RNA because it uses a different type of
nucleic acid called ribonucleic acid. The RNA is used in the next step, which is called
translation.

Translation

The next step in making a protein is called translation. This is when the RNA is converted (or
"translated") into a sequence of amino acids that makes up the protein.

The translation process of making the new protein from the RNA instructions takes place in a
complex machine in the cell called the ribosome. The following steps take place in the
ribosome.

 The RNA moves to the ribosome. This type of RNA is called the "messenger" RNA. It is
abbreviated as mRNA where the "m" is for messenger.
 The mRNA attaches itself to the ribosome.
 The ribosome figures out where to start on the mRNA by finding a special three letter
"begin" sequence called a codon.
 The ribosome then moves down the strand of mRNA. Every three letters represents
another amino acid molecule. The ribosome builds a string of amino acids based on the
codes in the mRNA.
 When the ribosome sees the "stop" code, it ends the translation and the protein is
complete.

How a ribosome makes a protein

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Different Types of Proteins

There are literally thousands of different types of proteins in our bodies. Here are a few of the
major groups and functions of proteins:

 Structural - Many proteins provide structure for our bodies. This includes collagen which
is found in cartilage and tendons.
 Defensive - Proteins help protect us from diseases. They make up antibodies that fight
off foreign invaders such as bacteria and other toxic substances.
 Transport - Proteins can help to carry essential nutrients around our bodies. One
example is hemoglobin which carries oxygen in our red blood cells.
 Catalysts - Some proteins, such as enzymes, act as catalysts to assist in chemical
reactions. They help us to break up and digest our food so it can be used by our cells.

Interesting Facts about Proteins and Amino Acids

 We get amino acids from basic foods such as chicken, bread, milk, nuts, fish, and eggs.
 Hair is made up of a protein called keratin.
 A special kind of RNA called transfer RNA moves the amino acids to the ribosome. It is
abbreviated as tRNA where the "t" stands for transfer.
 The bonds that link the amino acids in a protein together are called peptide bonds.
 The arrangement and type of different amino acids along the protein strand determines
the function of the protein.

VIDEO: https://www.youtube.com/watch?v=HSCUAjZQhXI

Exercise:
1. Which of the following is NOT one of the four main elements of an amino acid?
a. Hydrogen
b. Carbon
c. Nitrogen
d. Calcium
e. Oxygen

2. How many different kinds of amino acids are in our bodies?

a. 4
b. 12
c. 20
d. 180
e. 1,000

3. True or False: ALL amino acids in our bodies come from food.
a. TRUE
b. FALSE
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4. Proteins are made up of:

a. Short strands of RNA
b. Short strands of amino acids
c. Long chains of RNA
d. Long chains of amino acids
e. Different combinations of RNA and amino acids

5. What percentage of the human body is made up of proteins?

a. 5%
b. 10%
c. 20%
d. 50%
e. 100%

6. Why are proteins important?

a. Proteins are essential for survival
b. There are thousands of different proteins in the human body
c. Proteins provide all sorts of functions
d. Every cell in the human body uses proteins
e. All of the Above

7. Where are the instructions for how to make a protein located in a cell?
a. Membrane
b. Lysosomes
c. Ribosomes
d. Nucleus
e. Mitochondria

8. Which type of protein is found in cartilage or tendons?

a. Structural
b. Defensive
c. Transport
d. Catalysts
e. Enzymes

9. Catalysts perform which of the following functions?

a. Carry essential nutrients around our bodies
b. Assist in chemical reactions
c. Convert DNA into RNA
d. Provide structure for our bodies
e. Protect us from disease

10. The protein hemoglobin, which carries oxygen in our red blood cells, is an example of what
type of protein?
a. Structural
b. Defensive
c. Transport
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d. Catalysts
e. Enzymes