Human Genome

Overview:
Human genome is complete set of nucleic acid sequences for human. It is encoded
as DNA(Deoxyribonucleic acid) within the 23 chromosome pairs in cell
nucleous.22 pairs of chromosome are known as auto some and rest one pair of
chromosome is known as sex chromosome. This single pair of chromosome makes
sure that whether male or female.

Human genomes include both protein-coding DNA genes and non-coding DNA

.this coding is known as genetic coding. Which sequences are made with
combination of nitrogen bases. For DNA there are four nitrogen bases .they are
adenine, guanine, thiamin, cytosine and they are denoted respectively by A G T C.
adenine and thiamin are in Purina group and guanine and cytosine are in
pyramiding group. this four nitrogen bases can make sixty-four (64) combinations
for various types of criteria. A single combination of three bases denotes a single
criteria. There are 21 types of nucleic acids. They are also responsible for express
any criteria.

We can find similarities between two human or something using genetic coding.
we also can guess the evolution process by analyzing the similarities.

The International Human Genome Sequencing Consortium published the first draft
of the human genome in the journal Nature in February 2001 with the sequence of
the entire genome's three billion base pairs some 90 percent complete. A startling
finding of this first draft was that the number of human genes appeared to be
significantly fewer than previous estimates, which ranged from 50,000 genes to as
many as 140,000.The full sequence was completed and published in April 2003.

Upon publication of the majority of the genome in February 2001, Francis Collins,
the director of NHGRI, noted that the genome could be thought of in terms of a
book with multiple uses: "It's a history book - a narrative of the journey of our
species through time. It's a shop manual, with an incredibly detailed blueprint for
building every human cell. And it's a transformative textbook of medicine, with
insights that will give health care providers immense new powers to treat, prevent
and cure disease.

Although the sequence of the human genome has been completely determined by
DNA sequencing, it is not yet fully understood. Most (probably not all) genes have
been identified by a combination of high thought experiment
and bioinformatics approaches, yet much work still needs to be done to further
elucidate the biological functions of their protein and RNA products. Recent
results suggest that most of the vast quantities of non coding DNA within the
genome have associated biochemical activities, including regulation of gene
expression. organization of chromosome architecture, and signals
controlling epigenetic inheritance.