CNS

SEDATIVE AND HYPNOTICS

stages of sleep

rebound phenomenon

actions BZDs

why are BZDs free of residual effects ?

flumazenil

diazepam

phenobarbitone in neonatal jaundice

bzds is preffered over barbiturates

why are barbiturates contradictedin porphyria ?

acute barbiturate poisoning

melatonin

rameleon

drugs effecting REM

carbamazepine

zolpidem

use of intermedeiate and short acting barbiturates in insomnia

GENERAL ANESTHESIA

features of anesthesia 173

general protocol 173

minimum alveolar concentration 173

haloethane V IMP

CNS 1
 stages of anesthesia 174

general anesthetic classification page 174

second gas effect 177

diffusion hypoxia page 177

propfol 177

thiopentone sodium 178

thiopentone show redistribution phenomenon

ketamine 179

remifentanil page 179

preanesthetic medication 180

conscious sedation drugs used 181

A COMPLETE Q COMES ON GENERAL ANESTHETICS

Ketamine is prefferedover thipental sodium in GA

intravenous anethetic agents

balanced anesthesia

H2 blockers as pre anesthetic medications

atropine is used as a pre anesthetic

pancuronium provides cardiovascular stabillity

spinal anesthesia leads to hypotension

recovery from thiopentone sodium is rapid

balethene as general anesthetic agent

LOCAL ANESTHESIA

MOA of local anesthesia 182

why do local anesthetic do not work in inflammed and infected areas

182

adrenaline is administered along with xylocaine page 183

CNS 2
 why is bupivacaine not used as an LA ?

lignocaine page 186

obstetric analgensia age 186

epidural anesthesia

EMLA 186

oxethazaine page 186

drugs used for infiltration anesthesia —- lignocaine procaine

bupivacaine

spinal anesthesia

epidural anesthesia

lignocaine * propanolol page 189

use of local anesthethic in phenylepinehrine

ALCHOHOLS

acute alchol overdosage

treatment acute alchol overdoasage

chronic alcholism treatment

disulfiram

topiramate

methanol poisoming

ANTIEPILEPTICS

phenyoin

why is fosphenytoin preffered over phenytoin in status epilepticus

carbamazapine

oxcarmazapine

valproic acid

STATUS EPILEPTICUS

phenytoin sodium should not be used in petit grand mal epilepsy

CNS 3
 see table of newer epileptics

gabapentin

phenytoin and sodium valproate drug interactions

ANALGESICS

physical vs physiological dependence

actions of morphine

treatment of morphine dependence

methadone in morphine

acute morphine poisoning

morphine is contradicted in head injury

morphine is contradicted in asthma

morphine vs pethidine

morphine in emergency conditions

why is morphine given in LVF ?

endogenous opiod peptides 211

pethidine with oentazocine should be avoided in patient of MI

why is lopermaide used in diarhoea ?

why is atropine used with morphine in billiary colic

uses of oipods 206

tramadol 208

pentazozine

nuprenorphine

opiod antagnosit page 210

post operative pain

ANTIPARKINSONIAN

levodopa page 212

CNS 4
 on /off phenomenon 213

vitamine supplement must be given with L dopa in treatment of

parkinsonism

carbidopa

L dopa is not effective in drug induced parkinsonism

COMT inhibtors page 214

MAO

selegiline

ANTIPSYCHOTICS

cholrpromazine

haloperidol

beta blockers in anxiety

antidepressants

SSRIs

amitrypline

paroxetine

bipolar
lithium

CNS 5