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Answer the following questions as you proceed through the activity slides.
Neutrophil
a. Innate immunity: ______________________________________________________________
T-Lymphocytes
b. Adaptive immunity: ____________________________________________________________
Macrophage
c. Both adaptive and innate immunity: _______________________________________________
2. Define innate immune system.
nonspecific defence mechanisms, that come into play immediately or within hours of an antigen's appearance in the
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boy.
Bone Marrow/Thymus
3. Where are the cells of the adaptive immune system found in humans? ______________________
The purpose of humoral immunity is to generate the antibodies from the B-cells
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6. How does antibody specificity arise?
There is different sequences in the antigen binding site.
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Page 2 of 3 Cells of the Immune System—Student Worksheet
7. Outline the specific steps involved in antibody production in response to infection with human
immunodeficiency virus (HIV).
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Virus gets to the other side of the ski barrier, Its taken up by dendritic cell, The transports virus to lymph nodes, B-cells interact
w/HIV, it will then recognize it,transfoms into plasma cells,then it will produce antibodies, Finally the anitbodies go out to the
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bloodstream.
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8. Define antigen.
Its important in fighting infection because it gives signals that are picked up by cells (cells on Adaptive immune)
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11. A T cell is a type of white blood cell that has surface receptors that recognize antigens. Does an
individual T cell have the ability to recognize more than one type of antigen? Explain your answer.
No, they are interested and only bin to one specific antigen
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12. Explain the relationship between the antigen-presenting cells and helper T cells.
Helper T-cells have receptors that have the same shape of it antigen, that cells make Cytokines.
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13. Watch the video on slide 8 and answer the following questions.
a. What specifically results from the release of cytokines by helper T cells?
Chemical messengers that help the effective immune response.
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b. What is the problem with helper T cells carrying out this function in HIV infection?
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They have receptors, HIV uses them to get inside/into the cells
14. What role do cytotoxic T cells play in fighting infection?
TCRs and CD8 have surfaces and when TCRS have found the antigen they will kill the infected cells immediately
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15. What two molecules on the surface of a cytotoxic T cell help the cell recognize infected cells?
Tags the proteins,it also carried them to proteasome.Then they will go to the chain of peptides.
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17. What is the role of an MHC class 1 protein? Be specific.
CD8 molecules and Cytotoxic T-cells will go together with TCRs and will kill the cells.
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18. What is the relationship between an MHC class 1 protein and a cytotoxic T cell?
MHC2 is there helper of T-cells that help combine the TCRs, MHC 1 will kill the cells. While the CD8 and MHC2 turn into
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antigens
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