Introduction

-The recent kkk study has demonstrated that x, an inhibitor of y, resulted in a 38% reduction in
relative risk and a 42% risk reduction of hospitalization in patients with type 2 diabetes [1].

- Y inhibition also results in increased glucose excretion in diabetic patients.

-The previous findings do not suggest any beneficial effects of x on y.

-The mechanisms (causes) behind (underlying) these effects are still unknown.

-This study hypothesized that x has a direct effect on y.

-X and Y are drivers for Z.

-The study investigated whether x (1) directly reduces y; (2) increases z; and (3) changes L.