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Atomic Physics
Drs.Pristiadi Utomo, M.Pd
Atomic Physics
Introduction
Modern atomic and nuclear physics is among the most impressive scientific
achievements of the last century. Both the theories and techniques of atomic and nuclear
physics have played an important role in the life sciences. The theories provided a solid
foundation for understanding the structure and interaction of organic molecules, and the
techniques provided many tools for both experimental and clinical work. Contributions
from this field have been so numerous and influential that it is impossible to do them
justice in a single chapter. We will present a brief description of the atom and the
nucleus, which will lead into a discussion of the applications of atomic and nuclear
physics to the life sciences.
• It was subsequently discovered that the nucleus also contains another particle, the
neutron, which has approximately the same mass as the proton but is
electrically
neutral.
• Although the nucleus contains most of the atomic mass, it occupies only a small
part of
the total atomic volume. The diameter of the whole atom is on the order of 10−8
cm,
but the diameter of the nucleus is only about 10−13 cm.
Unfortunately, this classical model leads to a prediction of self- destruction when applied
to the atom. As the electron radiates, energy is carried away from the atom, the radius of
the electron′ s orbit steadily decrease as this radiation is given off and its frequency of
revolution increases. This process would lead to an ever-increasing frequency of emitted
radiation and the electron should eventually spiral into the nucleus and finally an
ultimate collapse of the atom occurs.
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Figure 2: Diagram representing Bohr′s model of hydrogen atom. The orbiting electron is allowed to be
2. Only certain electron orbits are stable. When in one of these stationary states, as Bohr
called them, the electron does not emit energy in the form of radiation. Hence the total
energy level of the atom remains constant and classical mechanics can be used to
describe the electron’s motion. This representation claims that the centripetally
accelerated electron does not continuously emit radiation, losing energy and
eventually spiraling into the nucleus, as predicted by Rutherford ′s planetary model.
3. Radiation is emitted by the atom when the electron makes a transition from a more
energetic initial orbit to a lower-energy orbit. This transition can not be visualized.
Bohr was able to calculate the radii of these allowed orbits and shows that, the
radiation or spectral lines are emitted as a consequence of orbital restrictions. The
orbital restrictions are most easily illustrated with the simplest atom hydrogen,
which has a single proton nucleus and one electron orbiting around it. Unless energy
is added to the atom, the electron is found in the allowed orbit closet to the nucleus. If
energy is added to the atom, the electron may “jump” to one of the higher allowed
orbits farther away from the nucleus, but the electron can never occupy the regions
between the allowed orbits (Figure 3).
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Figure 3: Bohr model for the hydrogen atom. The electron orbits about the nucleus and can occupy only
4. The Bohr model was very successful in explaining many of the experimental
observations for the simple hydrogen atom. But to describe the behavior of atoms
with more than one electron, it was necessary to impose an additional restriction on
the structure of the atom; the number of electrons in a given orbit cannot be greater
than 2n2, where n is the order of the orbit from the nucleus, trough which the
maximum number of electrons in each orbit can be calculated according to the
following:
The atoms are found to be constructed in accordance with these restrictions. Helium
has two electrons, and, therefore, its first orbit is filled. Lithium has three electrons,
two of which fill the first orbit; the third electron, therefore, must be in the second
orbit. This simple sequence is not completely applicable to the very complex atoms,
but basically this is the way the elements are constructed.
given atom the electron can have energy E1, E2, E3, and so on, but cannot have energy
between these two values. This is a direct consequence of the restrictions on the
allowed electron orbital configurations.
6. The lowest
energy level that an
electron can occupy
is called the ground
state. This
state is associated
with the orbital
configuration closest to the nucleus. The higher
allowed energy levels, called excited states, are associated with larger orbits and
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different orbital shapes. Normally the electron occupies the lowest energy level but it
can be excited into a higher energy state by adding energy to the atom.
7. An atom can be excited from a lower to a higher energy state in a number of different
ways. The two most common methods of excitation are:
(a) Electron impact.
(b) Absorption of electromagnetic radiation.
Transition between each pair of energy levels results, in the emission of light at a
specific frequency, called transition or resonance frequency. Therefore, a group of
highly excited atoms of a given element emit light at a number of well-defined
frequencies which constitute the optical spectrum for that element.
(b) An atom in a given energy level can also be excited to a higher level by light at a
specific frequency. The frequency must be such that each photon has just the right
amount of energy to promote the atom to one of its higher allowed energy states.
Atoms, therefore, absorb light only at the specific transition frequencies, given by
Equation 1. Light at other frequencies is not absorbed. If a beam of white light
(containing all the frequencies) is passed through a group of atoms of a given species,
the spectrum of the transmitted light shows gaps corresponding to the absorption of
the specific frequencies by the atoms. This is called the absorption spectrum of the
atom. In their undisturbed state, most of the atoms are in the ground state. The
absorption spectrum, therefore, usually contains only lines associated with transitions
from the ground state to higher allowed states (Figure 5). Optical spectra are produced
by the outer electrons of the atom. The inner electrons, those closer to the nucleus, are
bound more tightly and are consequently more difficult to excite. However, in a
highly energetic collision with another particle, an inner electron may be excited.
When in such an excited atom an electron returns to the inner orbit, the excess energy
is again released as a quantum (photon) of electromagnetic radiation. Because the
binding energy here is about a thousand times greater than for the outer electrons, the
frequency of the emitted radiation is correspondingly higher. Electromagnetic
radiation in this frequency range is called X - rays.
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8. The Bohr model also explained qualitatively the formation of chemical bonds. The
formation of chemical compounds and matter in bulk is due to the distribution of
electrons in the atomic orbits. When an orbit is not filled to capacity (which is the
case for most atoms), the electrons of one atom can partially occupy the orbit of
another. This sharing of orbits draws the atoms together and produces bonding
between atoms. As an example we show in Figure 6, the formation of a hydrogen
molecule from two hydrogen atoms.
(a) (b)
Figure 6: A schematic representation for the formation of a hydrogen molecule.
(a) Two separate hydrogen atoms.
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(b) When the two atoms are close together, the electrons share each other’s orbit, which results
in the binding of the two atoms into a molecule.
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and ultimately bulk matter, are formed. Atoms with completely filled orbits (these
are atoms of the so-called noble gases) as helium, neon, argon, krypton, and xenon,
cannot share electrons with other elements and are, therefore, chemically most inert.
2) Spectroscopy
Spectroscopy is the study of the wavelength distribution of radiation from a sample. The
absorption and emission spectra of atoms and molecules are unique for each species.
They can serve as fingerprints in identifying atoms and molecules in various substances.
Spectroscopic techniques were first used in basic experiments with atoms and molecules,
but they were soon adopted in many other areas, including the life sciences as:
• In biochemistry, spectroscopy is used to identify the products of complex
chemical
reactions.
• In medicine, spectroscopy is used routinely to determine the concentration of
certain
atoms and molecules in the body. From a spectroscopic analysis of urine, for
example,
one can determine the level of mercury in the body. Blood sugar level is
measured by
first producing a chemical reaction in the blood sample which results in a
colored
product. The concentration of this colored product, which is proportional to the
blood-
sugar level, is then measured by absorption spectroscopy.
The basic principles of spectroscopy are simple and characterized by two different
forms:
2.1) Emission Spectroscopy
In emission spectroscopy the sample under investigation is excited by an electric current
or a flame. The emitted light is then examined and identified. Emission spectra can
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provide information about the concentration of the various components in the substance.
In emission spectroscopy, the intensity of the emitted light in the spectrum is
proportional to the number of atoms or molecules of the given species.
components in the substance. The absorption spectra can also provide information about
the concentration of all the components in a substance. In absorption spectroscopy, the
amount of absorption can be related to the concentration.
Spectrometers used in routine clinical work are automated and can be operated by
relatively unskilled personnel. The identification and interpretation of the spectra
produced by less well-known molecules, however, require considerable training and
skill. In addition to identifying the molecule, such spectra also yield information about
the molecular structure.
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3) Quantum Mechanics
3.1) Overview
Quantum mechanics is the study of mechanical systems whose dimensions are close to
or below the atomic scale, such as molecules, atoms, electrons, protons and other
subatomic particles. Quantum mechanics is a fundamental branch of physics with wide
applications. Quantum theory generalizes classical mechanics and provides accurate
descriptions for many previously unexplained phenomena such as stable electron orbits.
The effects of quantum mechanics are typically not observable on macroscopic scales,
but become evident at the atomic and subatomic level. The word “quantum” came from
the Latin word which means "what quantity". In quantum mechanics, it refers to a
discrete unit that quantum theory assigns to certain physical quantities, such as the
energy of an atom at rest. The discovery that waves have discrete energy packets (called
quanta) that behave in a manner similar to particles led to the branch of physics that
deals with atomic and subatomic systems which we today call quantum mechanics.
As mentioned earlier, quantum mechanics is essential to understand the behavior of
systems at atomic length scales and smaller. For example, if Newtonian mechanics
governed the workings of an atom, electrons would rapidly travel towards and collide
with the nucleus, making stable atoms impossible. However, in the natural world the
electrons normally remain in an unknown orbital path around the nucleus (Figure 8).
Figure 8: The electrons orbiting the atomic nucleus in different orbits, with different energy levels.
This branch of physics was initially developed to provide a better explanation of the
atom, especially the spectra of light emitted by different atomic species. The quantum
theory of the atom was developed as an explanation for the electron's staying in its
orbital, which could not be explained by Newton's laws of motion and by Maxwell's
laws of classical electromagnetism. In the formalism of quantum mechanics, the state of
a system at a given time is described by a complex wave function (sometimes referred to
as orbital in the case of atomic electrons), and more generally, elements of a complex
vector space. This abstract mathematical object allows for the calculation of probabilities
of outcomes of concrete experiments. For example, it allows one to compute the
probability of finding an electron in a particular region around the nucleus at a particular
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time. Contrary to classical mechanics, one can never make simultaneous predictions of
conjugate variables, such as position and momentum, with arbitrary accuracy. For
instance, electrons may be considered to be located somewhere within a region of space,
but with their exact positions being unknown. Contours of constant probability, often
referred to as “clouds” may be drawn around the nucleus of an atom to conceptualize
where the electron might be located with the most probability (Figure 8).
The other exemplar that led to quantum mechanics was the study of electromagnetic
waves such as light. When it was found in 1900 by Max Planck that the energy of waves
could be described as consisting of small packets or quanta, Albert Einstein exploited
this idea to show that an electromagnetic wave such as light could be described by a
particle called the photon with a discrete energy dependent on its frequency. This
led to a theory of unity between subatomic particles and electromagnetic waves called
wave –particle duality in which particles and waves were neither one nor the other, but
had certain properties of both...
λ=h/p=h/mv (2)
From equation 2, the magnitude of the momentum p of a particle of mass m and speed v
is p = m v.
Furthermore, in analogy with photons, de Broglie postulated that a particle obey the
Einstein relation E = h ƒ (Equation 1), where E is the total energy of the particle. Then
the frequency of a particle is
ƒ=E/h
The dual nature of matter is apparent in these last two equations, because each contains
both particle concepts (m v and E) and wave concepts (λ and ƒ).
development of electron microscopes that can observe objects 1000 times smaller than
are visible with light microscopes.
The basic construction of an electron microscope is shown in Figure 9. The similarities
between the electron and the light microscope are evident; both have the same basic
configuration of two lenses which produce two-stage of magnification.
4.1) Measurements
• Electrons are emitted from a heated filament, and are then accelerated and
collimated
into a beam.
• The beam passes through the thin sample under examination which diffracts the
electrons in much the same way as light is diffracted in an optical microscope.
But
because of their short wavelength, the electrons are influenced by much smaller
Although it is possible to produce electrons with a wavelength much less than 10−10m
(1˚A), the theoretical optimum resolution implied by such short wavelengths has not yet
been realized. At present, the best resolution of electron microscopes is about 5 x 10−10 m
(5A˚).
These conditions, of course, present some limitations in the study of biological materials.
The samples have to be specially prepared for electron microscopic examination. They
must be dry, thin, and in some cases coated. Nevertheless, electron microscopes have
yielded beautiful pictures showing details in cell structure, biological processes, and
recently even large molecules such as DNA in the process of replication.
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5) X-rays
Introduction
X-rays are part of the electromagnetic spectrum. X-rays were first observed and
documented in 1895 by Wilhelm Conrad Roentgen, a German scientist who found them
quite by accident when experimenting with electron beams in a gas discharge tube.
Roentgen noticed that, a fluorescent screen in his lab started to glow when the electron
beam was turned on. This response in itself was not so surprising. Fluorescent material
normally glows in reaction to electromagnetic radiation, but Roentgen's tube was
surrounded by heavy black cardboard. Roentgen assumed this has blocked most of the
radiation. Roentgen placed various objects between the tube and the screen, and the
screen still glowed. A week later, he took an X-ray photograph of his wife's hand which
clearly revealed her wedding ring and her bone as shown in Figure 10. The photograph
electrified the general public and aroused great scientific interest in the new form of
radiation. Roentgen called it "X" to indicate it was an unknown type of radiation.
provide the continuous curve in Figure 11, which shows the cutoff of x-rays below a
minimum wavelength value that depends on the kinetic energy of the incoming
electrons. X-ray radiation with its origin in the slowing down of electrons or continuous
spectrum shown in the Figure is called Bremsstrahlung, the German word for “braking
radiation.”
Figure 11: The x – rays spectrum of a metal target consists of a broad continuous spectrum plus a number
of sharp lines, which are due to characteristic x-rays. The data shown were obtained when 37-
ke V electrons bombarded a molybdenum target.
• If the vacancy in the K (n = 1) shell is filled with electron dropping from the M
shell (n
= 3), the Kβ line in Figure 11 is produced.
[K β is a transition from level M (n = 3) to level K (n=1)]
Typically, the energy of such transition is greater than 1 000 eV, and the emitted photons
have wavelengths in the range of 0.01 nm to 1 nm.
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Other characteristic x-rays lines are formed when electrons drop from upper levels to
vacancies other than those in the K shell. For example, L lines are produced when
vacancies in the L shell are filled by electrons dropping from higher shells. An Lα lines is
produced as an electron drops from M shell (n = 3) to the L shell (n = 2), and an Lβ is
produced by a transition from the N shell (n = 4) to the L (n = 2) shell.
The voltage difference between the cathode and anode is extremely high, so the
electrons fly through the tube with a great deal of force. When a speeding electron
collides with a tungsten atom, it knocks loose an electron in one of the atom’s lower
orbital. An electron in a higher orbital immediately falls to the lower energy level,
releasing its extra energy in the form of a photon. It’s a big drop, so the photon has a
high energy level; it is an X-ray photon (Figure 13).
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Figure 13: The free electron collides with the tungsten atom, knocking an electron out of a lower orbital.
A higher orbital electron fills the empty position, releasing its excess energy as a photon.
The high-impact collisions involved in x-ray production generate a lot of heat. A motor
rotates the anode to keep it from melting (the electron beam isn’t always focused on the
same area). A cool oil bath surrounding the envelope also absorbs heat. The entire
mechanism is surrounded by a thick lead shield. This keeps the x-rays from escaping in
all directions. A small window in the shield lets some of the x-ray photons escape in a
narrow beam. The beam passes through a series of filters on its way to the patient. A
camera on the other side of the patient records the pattern of x-ray light that passes all
the way through the patient’s body (Figure 12).
Generally, doctors keep the film image as a negative. That is, the areas that are exposed
to more light appear darker and the areas that are exposed to less light appear lighter.
Hard material, such as bone, appears white, and softer material appears black or gray.
Finally, from the preceding discussion, one can show that two different processes give
rise to radiation of x-ray frequency:
• In one process; radiation is emitted by the high - speed electrons themselves as
they
are slowed or even stopped in passing near the positively charged nuclei of the
anode
material. This is the Brehmsstrahlung radiation.
• In a second process; radiation is emitted by the electrons of the anode atoms
when
incoming electrons from the cathode knock electrons near the nuclei out of
orbit and
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they are replaced by other electrons from outer orbits. X - rays produced in this
way
have definite energies just like other line spectra from atomic electrons. They
are
Characteristic x-rays. The spectral lines generated depend on the target (anode)
element used and thus are called characteristic lines.
In medical applications, the target (anode) is usually tungsten or a more crack resistant
alloy of rhenium (5%) and tungsten (95%), but sometimes molybdenum for more
specialized applications, such as when soft x-rays are needed as in mammography.
In general, the spectrum of frequencies given off with any particular anode material thus
consists of a continuous range of frequencies emitted in the first process, and
superimposed on it a number of sharp peaks of intensity corresponding to discrete
frequencies at which x- rays are emitted in the second process.
tumor is located. Several tomographic techniques (CT scans) have been developed to
produce slice-images within the body which provide depth information. Presently the
most commonly used of these is x-ray computerized tomography (CT scan) developed
in the 1960. The basic principles of the technique in its simplest form illustrated in
Figure 14 are:
• A thin beam of x-rays passes through the plane we want to visualize and is
detected by
a diametrically opposing detector.
• For a given angle with respect to the object (in this case the head), the x-ray
source-
detector combination is moved laterally scanning the region of interest as
shown by the
arrow in Figure 14 (a).
• At each position, the detected signal carries integrated information about x-ray
transmission properties of the full path in this case A−B.
• The angle is then changed by a small amount (about 1˚) and the process is
repeated full
circle around the object.
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The visualized slices within the body obtained in this way are typically about 2 mm
thick. In the more recent versions of the instrument, a fan rather than a beam of x-rays
scans the object, and an array of multiple detectors is used to record the signal. Data
acquisition is speeded up in this way yielding an image in a few seconds.
5.3.2 Biology
Crystallography: x-rays have also provided valuable information about the structure of
biologically important molecules. The technique used here is called crystallography and
can be expressed as follows:
The wavelength of x-rays is on the order of 10−10 m, about the same as the distance
between atoms in a molecule or crystal. Therefore, if a beam of x- rays is passed through
a crystal, the transmitted rays produce a diffraction pattern that contains information
about the structure and composition of the crystal. The diffraction pattern consists of
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regions of high and low x-ray intensity which when photographed show spots of varying
brightness (Figure 15).
Diffraction studies are most successfully done with molecules that can be formed into a
regular periodic crystalline array. Many biological molecules can in fact be crystallized
under the proper conditions. It should be noted, however, that the diffraction pattern is
not a unique, unambiguous picture of the molecules in the crystal. The pattern is a
mapping of the collective effect of the arrayed molecules on the x-rays that pass through
the crystal. The structure of the individual molecule must be deduced from the indirect
evidence provided by the diffraction pattern.
If the crystal has a simple structure such as sodium chloride, the x-ray diffraction pattern
is also simple and relatively easy to interpret. Complicated crystals, however, such as
those synthesized from organic molecules, produce very complex diffraction patterns.
But, even in this case, it is possible to obtain some information about the structure of the
molecules forming the crystal. To resolve the three-dimensional features of the
molecules, diffraction patterns must be formed from thousands of different angles. The
patterns are then analyzed, with the aid of a computer. These types of studies provided
critical information for the determination of the structure for penicillin, vitamin B12,
DNA, and many other biologically important molecules.
X-ray radiation is used for imaging internal body structures, hard and soft tissue, for
diagnosis; x-rays hard tissues such as bones and teeth absorb more x-rays and show as
lighter areas on x-ray film; A contrast medium can be used to highlight soft tissues in
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still x-ray pictures, or can be followed on x-ray motion-picture films as it moves through
the body or part of the body to record body processes.
Contrast Medium; in a normal x-ray picture, most soft tissue doesn't show up clearly.
To focus in on organs, or to examine the blood vessels that make up the circulatory
system, doctors must introduce contrast media into the body. Contrast media are liquids
that absorb x-rays more effectively than the surrounding tissue. To bring organs in the
digestive and endocrine systems into focus, a patient will swallow a contrast media
mixture, typically a barium compound. If the doctors want to examine blood vessels or
other elements in the circulatory system, they will inject contrast media into the patient's
bloodstream.
Arthrography (Joint x-ray): Arthrography is the x-ray examination of joint that uses a
special form of x-ray called fluoroscopy and a contrast material containing iodine.
Fluoroscopy makes it possible to see internal organs in motion. When iodine is injected
into the joint space, it coats the inner lining of the joint structures and appears bright
white on an arthrogram, allowing the radiologist to assess the anatomy and function of
the joint (areas where the dye leaks out indicate a tear in the tendons). Arthrographic
images help physicians evaluate alterations in structure and function of a joint and help
to determine the possible need for treatment, including surgery or joint replacement. The
procedure is most often used to identify abnormalities within the shoulder, wrist, hip,
knee (Figure 16), and ankle.
Mammography: Mammography is a specific type of imaging that uses a low dose x-ray
system to examine breasts. A mammography exam, called a mammogram, is used to aid
in the diagnosis of breast diseases.
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Bone X-ray: A bone x-ray shows images of bones in the body, including the hand
(Figure 17), wrist, arm, foot, ankle, knee and leg. A bone x-ray is used to determine
whether a bone has been fractured or if a joint is dislocated. It also can ensure that a
fracture has been properly aligned and stabilized for healing following treatment. The
image can show whether there is a build up of fluid in the joint or around a bone. It can
also evaluate injury or damage from conditions such as infection, arthritis, abnormal
bone growths or other bone diseases, such as osteoporosis. This technique is also used to
assist in the detection and diagnosis of cancer.
Figure 18: This image shows the right side of the large intestine. Air (dark) distends the bowel and barium
Renal Examination: X-raying the kidneys, are usually done after injecting a contrast
medium into a vein. A series of x-rays is then taken to show the renal outline and
collecting system and structures of the kidneys, as well as ureters and the bladder.
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Dental X-rays: Structures that are dense (such as silver fillings or metal restoration) will
block most of the photons and will appear white on developed film. Air beneath the
teeth will be black on film, teeth and tissue will appear as shades of gray. The test is
performed in the dentist's clinics. There are four types of x-rays:
1. Bite-wing: The bite-wing is when the patient bites on a paper tab and shows the crown
Figure 19: Bite-Wings X-rays are some of the most typical x-rays a Dentist will take. These types of x-
rays are very effective at discovering tooth decay. It is called Bitewing because the x-ray
film holder provides a surface to bite down on and hold the x-ray securely in place.
2. Periapical X-rays: The periapical x-rays shows one or two complete teeth from crown
to root (Figure 20).
Figure 20: Periapical X-rays are taken to get a more effective examination of the entire tooth area from
crown to root. These types of x-rays provide a complete side view and typically a complete
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set consists of 14 films with each tooth appearing in two different films from two different
angles.
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3. Occlusal X-rays: Occlusal x-ray captures the upper or the lower teeth in one shot,
while the film rests on the biting surface of the teeth (Figure 21).
Figure 21: Occlusal X-rays are less common than either Bite-Wing or Periapical X-rays. These types of
x-rays are taken to show the lower or the upper jaw.
4. Panoramic: Panoramic x-ray requires a special machine that rotates around the head.
The x-ray captures the entire jaws and teeth in one shot. It's used to plan treatment for
dental implants, check for impacted wisdom teeth, and detect jaw problems. A
panoramic x-ray is not good for detecting cavities, unless the decay is very advanced
and deep( Figure 22).
Figure 22: Panoramic or Panorex (a type of film) X-ray is also very commonly done on an "initial" visit
of a dentist. As the name suggests, a Panoramic X-ray makes a complete half circle from ear
to ear to produce a complete two dimensional representation of all teeth. Panoramic X-rays
give the dentist an overall picture of all your teeth and jaw bones.
In General, dental x-rays may be used to identify the number, size, and position of teeth,
unemerged or impacted teeth, the presence and extent of dental cavities, bone damage
(such as from periodontitis), abscessed teeth, fractured jaw.
characteristics of cancer cells is that they grow and divide faster than normal cells.
Radiation also damages normal cells, but because normal cells are growing more slowly,
they are better able to repair radiation damage than are cancer cells. In order to give
normal cells time to heal and reduce side effects, radiation treatments are often given in
small doses over a six or seven week period. It is used in more than half of all cancer
cases. Radiation therapy can be used in different ways:
• Alone to kill cancer.
• Before surgery to shrink a tumor and make it easier to remove.
• During surgery to kill cancer cells that may remain in surrounding tissue after the
surgery.
• After surgery to kill cancer cells remaining in the body.
• To shrink an inoperable tumor in order to reduce pain and improve quality of life in
combination with chemotherapy.
6) Lasers
In this section, we will explore the nature of laser light and apply our knowledge of
atomic structure to describe the mechanism involved in the operation of laser. This will
be followed by describing a variety of applications of lasers in our technological society.
name indicates one of the requirements for laser light: this means that, to achieve laser
action, the process of stimulated emission must occur.
Suppose an atom is in the excited state E2, as in Figure 23, when a photon with energy
hƒ= E2 – E1 is incident on it, we can show that:
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• The incoming photon can stimulate the excited atom to return to the ground state and
thereby emit a second photon having the same energy hƒ and traveling in the same
direction. The incident photon is not absorbed, so after the stimulated emission, there
are two identical photons: the incident photon and the emitted photon. The emitted
photon is in phase with the incident photon.
• These photons can stimulate other atoms to emit photons in a chain of similar
processes. The many photons produced in this fashion are the source of the intense,
coherent light in a laser.
are typically 10-8s. In this case, the population inversion can be established and
stimulated emission is likely to occur before spontaneous emission as shown in
Figure 24.
[Spontaneous emission; Once an atom is in an excited state, the excited atom can
make a transition to a lower energy level, because this process happens naturally, it is
known as spontaneous emission].
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Figure 24: Spontaneous emission of a photon by an atom that is initially in the excited state E 2.
When the atom falls to the ground state, it emits a photon of energy hƒ = E2 – E1.
3. The emitted photons must be confined in the system long enough to enable them to
stimulate further emission from other excited atoms. That is achieved by using
reflecting mirrors at the ends of the system. One end is made totally reflecting, and the
other is partially reflecting. A fraction of the light intensity passes through the
partially reflecting end, forming the beam of laser light (Figure 25).
mirrors confine the photons to the tube, but mirror 2 is only partially reflective.
A red laser contains a long crystal made of ruby as shown in Figure 26 as a red bar with
a flash tube (yellow zig-zag lines) wrapped around it. The flash tube looks a bit like a
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fluorescent strip light, only it's coiled around the ruby crystal and it flashes every so
often like a camera's flash gun.
Figure 26: A construction for laser light by using a crystal and a flash tube.
The following represents how the flash tube and the crystal make laser light:
1. A high-voltage electric supply makes the tube flash on and off.
2. Every time the tube flashes, it "pumps" energy into the ruby crystal. The flashes it
makes inject energy into the crystal in the form of photons.
3. Atoms in the ruby crystal (large green blobs) soak up this energy in an absorption
process. When an atom absorbs a photon of energy, one of its electrons jumps
from a low energy level to a higher one. This puts the atom into an excited state, but
makes it unstable. Because the excited atom is unstable, the electron can stay in the
higher energy level only for a few milliseconds. It falls back to its original level,
living off the energy it absorbed as a new photon of light radiation (small blue blob).
This is the spontaneous emission process.
4. The photons that atoms give off zoom up and down inside the ruby crystal, traveling
at the speed of light.
5. Every so often, one of these photons hits an already excited atom. When this happens,
the excited atom gives off two photons of light instead of one. This is the stimulated
emission described earlier. Now one photon of light has produced two and the light
has been amplified (increased in strength). In other words, "light amplification" (an
increase in the amount of light) has been caused by "stimulated emission of radiation"
(hence the name "laser", because that's exactly how a laser works!)
6. A mirror at one end of the laser tube keeps the photons bouncing back and forth inside
the crystal.
7. A partial mirror at the other end of the tube bounces some photons back into the
crystal but lets some escape.
8. The escaping photons form a very concentrated beam of powerful laser light.
Lasers are classified into four broad areas depending on the potential for causing
biological damage. Safety thresholds for lasers are expressed in terms of Maximum
Drs.Pristiadi Utomo, M.Pd
Permissible Exposure (MPE). When you use a laser, it should be labeled with one of
these four classes designations:
Class 1
These lasers cannot emit laser radiation at known hazard levels under normal operating
conditions, because they are completely enclosed (prohibit or limits access to the laser
radiation). Examples of this class are: laser printers and laser disc players.
Class 1a
This is a special designation that applies only to lasers that are "not intended for
viewing," such as a supermarket laser scanner. The upper power limit of class1a is 4.0
mW.
Class 2
These are low-power visible lasers that emit above class 1 levels but at a radiant power
not above 1 mW. The concept is that the human aversion reaction to bright light will
protect a person and are capable of creating eye damage through chronic exposure. The
human eye blink reflex, which occurs within 0.25 seconds of exposure to Class 2 laser
beam. Examples are: Helium-Neon lasers and some laser pointers.
Class 3a
These are intermediate - power lasers from 1 to 5 mW, which are hazardous only for
intra-beam viewing. A warning label shall be placed on or near the laser in a
conspicuous location of caution users, to avoid staring into the beam or directing the
beam toward the eye of individuals. Example of this type of laser: Helium-Neon lasers,
some solid state laser pointers and most pen-like pointing lasers are in this class.
Class 3b
These are moderate-power lasers from 5 mW to 500 mW . These lasers will produce an
eye hazard if viewed directly.
Class 4
These are high-power lasers from 500 mW if continuous wave (cw), or 10 J/cm2 if
pulsed, which are hazardous to view under any condition.
Dye Lasers: use complex organic dyes, such as rhodamine 6G, in liquid solution or
suspension as lasing media. They are tunable over a broad range of wavelengths
Semiconductor Lasers: sometimes called diode lasers, are not solid- state lasers. These
electronic devices are generally very small and use low power. They may be built into
larger arrays, such as the writing source in some laser printers , laser pointers or CD
players.
6.5) Applications
There are many scientific, military, medical and commercial laser applications which
have been developed since the invention of the laser in the 1958. The coherency, high
monochromatic, and ability to reach extremely high powers, are all properties which
allow for these specialized applications of laser.
Commercial: The most widespread use of lasers is in optical storage devices
such as compact disc and DVD players, in which the laser (a few millimeters in size)
scans the surface of the disc. Other common applications of lasers are bar code readers,
laser printers and laser pointers.
Medicine: Bloodless surgery, laser healing, surgical treatment, kidney stone treatment,
eye treatment, dentistry.
Defense: Marking targets, guiding munitions, missile defense, electro-optical
countermeasures (EOCM) and alternative to radar.
Research: Spectroscopy, laser ablation, laser annealing, laser scattering, laser
interferometer.
Industry: Lasers are used for cutting and welding the steel and other metals and for
inscribing patterns (such as the letters on computer Key boards).
6.5.1 Medical Applications
Because various laser wavelengths can be absorbed in specific biological tissues, lasers
have a number of medical applications:
• Certain laser procedures have greatly reduced blindness in patients with glaucoma and
diabetes. Glaucoma is a widespread eye condition characterized by a high fluid
pressure in the eye, a condition that can lead to destruction of the optic nerve. A simple
laser operation, (iridectomy) can “burnˮ open a tiny hole in a clogged membrane
relieving the destructive pressure. A serious side effect of diabetes is
neovascularization, the proliferation of weak blood vessels, which often leak blood.
When neovascularization occurs in the retina, vision deteriorates (diabetic retinopathy)
and finally is destroyed. Today, it is possible to direct the green light from an argon ion
laser through the clear eye lens and eye fluid, focus on the retina edges, and
photocoagulate the leaky vessels. Even people who have only minor vision defects
such as nearsightedness are benefiting from the use of lasers to reshape the cornea,
changing its focal length and reducing the need for eyeglasses.
• Laser surgery is now an everyday occurrence at hospitals and medical clinics around
the word. Infrared light at 10 μ m from a carbon dioxide laser can cut through muscle
tissue, primarily by vaporizing the water contained in cellular material. Laser power of
approximately 100 W is required in this technique. The advantage of the “laserˮ knife
over conventional methods is that laser radiation cut tissue and coagulates blood at the
same time, leading to a substantial reduction in blood loss. In addition, the technique
Drs.Pristiadi Utomo, M.Pd
virtually eliminates cell migration, an important consideration when tumors are being
removed.
• A laser beam can be trapped in fine optical fiber light guides (endoscopes) by means of
total internal reflection. An endoscope can be introduced through natural orifices,
conducted around internal organs, and directed to specific interior body locations,
eliminating the need for invasive surgery. For example, bleeding in the gastrointestinal
tract can be optically cauterized by endoscopes inserted through the patient's mouth.
• In medical and biological research, it is often important to isolate and collect unusual
cells for study and growth. A laser cell separator exploits the tagging of specific cells
with fluorescent dyes. All cells are then dropped from a tiny charged nozzle and laser-
scanned for the dye tag. If triggered by the correct light-emitting tag, a small voltage
applied to parallel plates deflects the falling electrically charged cell into a collection
beaker.
6.5.2 Laser surgery
Before lasers could be successfully used in surgical procedures, a wide range of studies
had to be conducted to understand the effect of intense light on various types of tissues.
Further, technology had to be developed for precise control of light intensity and
duration and for accurate positioning of the focal point. While the surgical use of lasers
is growing in many areas of medicine and dentistry, the positional accuracy of laser
tissue-removal is particularly important in neurosurgery and eye surgery where a fraction
of a millimeter offset can make the difference between success and failure.
Dermatology
In laser skin resurfacing, a laser is used to remove areas of damaged or wrinkled skin,
layer by layer. The procedure is most commonly used to minimize the appearance of fine
lines, especially around the mouth and the eyes. However, it is also effective in treating
facial scars or areas of uneven pigmentation, sun damaged skin, acne scars, broken blood
vessels, wrinkles, (Figure 27 (a), (b) and (c)) and facial redness. Laser resurfacing may
be performed on the whole face or in specific regions.
(a) (b)
(c)
Figure 27: (a) Acne Scars, (b) Broken Blood Vessels, and (c) Wrinkles.
Drs.Pristiadi Utomo, M.Pd
Ophthalmology
Ophthalmologists were among the first to use lasers for a wide range of procedures.
Figure 28 describes the treatment of the disorder of the eye to restore normal vision
(lasik eye surgery).
(a) The cornea is the transparent part of the eye that covers the iris. It is also the main
(a)
(b) Anesthetic eye drops are given to numb the eye, and the surgeon marks the cornea
with water-soluble ink to guide replacement of the corneal flap.
(b)
(c) The surgeon performs a keratectomy which creates a corneal flap. The flap is lifted
and reflected exposing the cornea beneath (A keratectomy is a procedure that uses a
small instrument that makes a cut in the cornea as it moves across it).
Drs.Pristiadi Utomo, M.Pd
(c)
(d) A computer-controlled laser reshapes the cornea to the prescribed shape for clear
vision.
(d)
(e) The corneal flap is repositioned and bonds to the cut edge of the cornea quickly.
(e)
Figure 28: Lasik Eye Surgery.
Drs.Pristiadi Utomo, M.Pd
Oncology
Laser procedure promises to eliminate the need for radiation, preserve speech, shorten
treatment time and significantly improve care in other ways for many patients whose
cancer is diagnosed early. The therapy uses heat from laser to destroy the tumor’s blood
supply and cancer cells, which damages surrounding tissues far less than radiation and
different types of lasers.
Otolaryngology
Otolaryngology is the use of laser systems for excising skin tumors, cancers, birthmarks
and other disorders of the head and neck; problems of the voice box, throat, mouth, nose
and ear may be amenable to different laser treatments. Nodules or polyps on the larynx
and blood vessel defects in the upper airway are disorders that could be treated with
laser. In another instance, laser surgery might be performed to remove the stapes from
the middle ear for treatment of otosclerosis. A new outpatient could eliminate the need
for radiation in treating early cancer of the larynx, or voice box. Pulses of green laser
light selectively destroy blood vessels feeding the tumor without burning the vocal cords
as shown in Figure 29.
Figure 29: The use of laser in treating tumor in the voice box.
Finally, laser Surgery is often referred to as "bloodless surgery," laser procedures usually
involve less bleeding than conventional surgery. The heat generated by the laser keeps
the surgical site free of germs and reduces the risk of infection. Because a smaller
incision is required, laser procedures often take less time (and cost less money) than
traditional surgery. Sealing off blood vessels and nerves reduces bleeding, swelling,
scarring, pain, and the length of the recovery period.
Drs.Pristiadi Utomo, M.Pd
Dental Laser
A dental laser (Figure 30) is a type of laser designed specifically for use in oral surgery
or dentistry.
Lasers are so precise in what they can do; there are several unique types of lasers used in
dentistry for varied purposes in hard or soft tissue. They are designed with different
wavelengths that have different absorption capabilities that recognize and interact with
different types of human tissue. For example,longer wave lasers such as the Er: YAG
(erbium) lasers, are used for teeth and bone because they have an affinity for water and
can recognize the decayed part of the tooth because of the differences in water content
between solid and decayed tooth structure.
The laser emits light energy either in continuous or pulsed states. Most dental lasers
involve pulsed energy release. The pulse, or burst of light, delivers the laser’s heat
energy quickly (each pulse lasts only a few ten thousandths of a second) and then allows
the tissue a time to cool before initiating another blast. This heat energy pulse works by
either boiling away water within and between the cells, or by causing micro expansion of
hard tissue, resulting in a tiny explosion that removes the unwanted tissue. The
procedure consists of a series of “pops” that work to remove decay or cut away tissue or
tooth structure.
When laser used for surgical procedures, it acts as a cutting instrument or a vaporizer of
tissue. When used for cutting, a-filling, the laser helps to strengthen the bond between
the filling and the tooth. When used in teeth whitening procedures, the laser acts as a
heat source.
Several variants of dental laser are in use, with the most common being diode lasers,
carbon dioxide lasers and yttrium aluminum garnet laser. Different lasers use different
wavelengths and these mean they are better suited for different applications. For
example, diode in the 810–900 nm range are well absorbed by red colored tissues such
as the gingival, increasingly being used in place of electro surgery and standard surgery
for soft tissue applications such as tissue contouring and gingivectomy.
There are many different types of dental lasers, but all can be classified as one of two
kinds of hard or soft tissue dental lasers. Laser dentistry is a new technique that can
Drs.Pristiadi Utomo, M.Pd
improve the precision of your treatment while minimizing pain and recovery time
(Figure 31).
The application of lasers in dentistry opens the door for dentists to perform a wide
variety of dental procedures; they otherwise may not be capable of performing as:
• Benign Tumors: Dental lasers may be used for the painless and suture-free
removal of
benign tumors from the gums, palate, sides of cheeks, and lips.
• Cavity Detector: Low intensity soft tissue dental lasers may be used for the
early
detection of cavities by providing a reading of the by-products produced by
decay.
• Tooth and Gum Tissues: Optical Coherence Tomography (CT scan) is a safer
way to
see inside tooth and gums in real time.
• Cold Sores: Low intensity dental lasers reduce pain associated with cold sores
and
minimize healing time.
• Crown Lengthening: Dental lasers can reshape gum tissue and bone to expose
healthier tooth structure. Such reshaping called crown lengthening; provides a
stronger
foundation for a restoration.
• Dental Fillings: Hard tissue dental lasers may eliminate the need for a local
anesthetic
injection and the traditional turbine drill. Lasers used in dental filling
procedures are
capable of killing bacteria located in a cavity and this may lead to better long
term
tooth restorations.
• Soft Tissue Folds (Epulis): Dental lasers may be used for the painless and
suture-free
removal of soft tissue folds often caused by ill-fitting dentures.
Drs.Pristiadi Utomo, M.Pd
• Teeth Whitening: Low intensity soft tissue dental lasers may be used to speed
up the
bleaching process associated with teeth whitening and with the use of a
whitening gel.
The translucent bleaching gel is applied to the teeth and a laser light is used to
activate
the crystals to absorb the energy from the light and penetrate the teeth enamel
to
increase the lightening effect on the teeth. The length of time in the cosmetic
dentist's
chair depends on the degree of discoloration you have (Figure 32).
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Drs.Pristiadi Utomo, M.Pd
Assignment 5
1-Explain the operation of a spectrometer and describe two possible uses for this device.
2-How are X ray produced?
3-What are the applications of X rays in medicine?
4-Describe the 4 types of X ray images used in dentistry.
5-Describe the process of X-ray computerized tomography. What information does this
process provide that ordinary X-ray images do not?
6-Calculate the frequency of a photon of energy 4.8 x 10-19 J;
[ƒ= 7.24 X 1014 Hz]
7-Calculate the de Broglie wavelength for a proton moving with a speed of 106m/s.
[mass of proton = 1.67 X 10-27 kg]
[λ = 3.97 X 10-13m]
8-Describe the operation of a laser. Include a description of the method for obtaining the
inverted population distribution.
9-What are the applications of laser in medicine in general and in dentistry in particular?
Drs.Pristiadi Utomo, M.Pd
References:
1)Serway, R. and Jewett, J., Physics for Scientists and Engineers with Modern Physics,