Sie sind auf Seite 1von 4

Disease and Role of MicroRNA

Disease Sample MicroRNA Dysregu Reference


lation
Liver pathology Serum miR-122-5p Up (Brunetto et al.,
HBV infection miR-99a-5p 2014)
miR-192-5p
Acute Hepatitis C Serum miR-122 Up (J. hua Wang et
Chronic Hepatitis C al., 2015)
(CHC)
Non-Alcoholic Fatty Serum miR-34a Up (Salvoza et al.,
Liver Disease (NAFLD) miR-122 2016)

Acetaminophen (APAP) Serum miR-4454-5p Down (Ward et al.,


miR-4516 2014)
miR-4286-5p
Non-Alcoholic Fatty Serum miR-122 Up (Martino et al.,
Liver Disease (NAFLD) 2015)
Hepatocellular Plasma miR-21 Up (Tomimaru et al.,
Carcinoma 2012)
(HCC)
Chronic hepatitis B Plasma/seru miR-122 Up (X. Zhang et al.,
Chronic hepatitis C m 2014)
chronic hepatitis B- Serum miR-122 Up (W. J. Wang et
related al., 2016)
liver failure (CHBLF)
HCV-infected human Serum miR-122 Up (Marquez et al.,
liver biopsies miR-21 2010)
hepatitis C virus (HCV) serum miR-122, miR- Up (S. Zhang et al.,
134 miR-424-3p 2015)
miR-629-5p

Hepatitis C virus (HCV) Infected miR-122 Up (Cox et al., 2013)


cultured cell

liver cirrhosis (LC) serum miR-29 Down (Xing et al.,


hepatitis B virus (HBV) 2014)
miR-122 Up
Hepatocellular carcinoma
(HCC)
Hepatitis B virus (HBV) Plasma miR-23b Up (Jin et al., 2015)
miR-122, miR-
150 miR-122-5p,
miR-192-5p
Hepatitis C virus (HCV) miR-143 Up
miR-21
Liver Cirrhosis (LC) miR-1 Up
miR-451a,
miR-18a-5p
miR-29c-3p
miR-106b-5p
miR-185-5p
Liver fibrosis Liver Biopsy miR-29 down (Roderburg et al.,
2011)
Hepatitis B virus (HBV) Tissue miR-22 down (Shi and Xu,
Hepatocellular carcinoma sample 2013)
(HCC)
Cirrhosis Serum miR-122 Up (Akamatsu and
Hepatocellular carcinoma miR-99a Hayes, 2015)
(HCC) miR-125b
miR-720
miR-22
Hepatocellular cancer Tissue miR-29 Up (Braconi et al.,
Sample 2011)

Acute Liver Failure Serum miR-122 Up (Dubin et al.,


Chronic Hepatitis C 2016)

Liver fibrosis Serum miR-122, miR- Up (Cermelli et al.,


Hepatocellular carcinoma 34a miR-16 2011)
miR-2
Alcoholic liver disease serum/plasm miR-155 Up (Bala et al., 2013)
(ALD) a miR-146a
Acetaminophen(APAP) miR-125b
Toll-like receptor (TLR)
Drug induced liver injury miR-122 Down
(DILI)

Non-alcoholic Serum miR-21 Up (Becker et al.,


steatohepatitis (NASH) profiles miR-122 2015)
miR-192
Hepatocellular carcinoma Plasma miR-122 Up (Zhou et al.,
(HCC) miR-192 2011)
miR-21
miR-223
miR-26a
miR-27
miR-801
Hepatocellular carcinoma Plasma miR-20a-5p Up (Wen et al., 2015)
(HCC) miR-25-3p
miR-30a-5p
miR-92a-3p
miR-132-3p
miR-185-5p
miR-320a
miR-324-3p

chronic hepatitis B Serum miR-122 down (H. Zhang et al.,


(CHB) miR-575 2012)
miR-575
miR-638
miR-744
Hepatocellular carcinoma Serum miR-143 UP (Z. Zhang et al.,
(HCC) miR-215 2014)

Hepatitis B virus(HBV) serum miR-25 Up (Qi et al., 2011)


Hepatocellular carcinoma miR-375
(HCC) let-7f
Chronic Hepatitis B virus Serum miR-29a Up (Huang et al.,
(HBV) miR-29b 2014)
miR-29c
Chronic Hepatitis C virus Serum miR-122 Up (Waidmann et al.,
(HCV) 2013)

Chronic Hepatitis B Serum miR-210 Up (F. Yu et al.,


(CHB) 2015)

Liver fibrosis serum miR-19a, miR- Up (Motawi et al.,


Hepatocellular carcinoma 296 2015)
(HCC) miR-130a, miR-
195
miR-192
miR-34a, miR-
146
Chronic Hepatitis B Serum miR-18a Up (Sohn et al.,
(CHB) miR-221 2015)
Liver cirrhosis (LC) miR-222
Hepatocellular carcinoma miR-224
(HCC)
miR-101 Down
miR-106b
miR-122
miR-195
Hepatocellular carcinoma Hepatoma miR-19a Up (G. Yu et al.,
(HCC) cells 2016)
miR-122 Down
miR-223
HBV related HCC Liver tissues miR-23a Down (Ura et al., 2009)
HCV related HCC miR-26a
miR-27a
miR-92
miR-200a
miR-26a Up
miR23a
miR-27a
miR-200a
miR-92