Herzzentrum

UniversitŠtsspital Basel
Herzzentrum

Herzzentrum
Jahresbericht 2016
 Vorwort

Mehr wissen. Alles geben.

Mehr machen. Besser kšnnen.
Zusammen arbeiten. Mehr erreichen.
Diese Axiome fokussieren unsere Arbeit im Herzzentrum des UniversitŠtsspitals auf das Wesentliche:
Gemeinsam mehr erreichen fŸr eine optimale, Ÿberregionale Patientenversorgung, fŸr eine fundierte
Aus- und Weiterbildung, fŸr die universitŠre Wissenschaft, fŸr ein nachhaltiges Gesundheitssystem.
Diesen GrundsŠtzen folgend haben wir den diesjŠhrigen Jahresbericht auf das Wesentliche reduziert:
Teams, Zahlen, Fakten, Lehre & Forschung.

DafŸr stehen wir und unser Herzteam.

Friedrich Eckstein Stefan Osswald

02 03
 Inhalt
01 Dienstleistungen 06 - 11
Leistungsstatistik Kardiologie UniversitŠtsspital
Leistungsstatistik Herzchirurgie UniversitŠtsspital
Leistungsstatistik PartnerspitŠler
Outcomestatistik

02 Kardiologie 12 - 23
Interventionelle Kardiologie
Elektrophysiologie
Echokardiographie
Cardiac Imaging
Herzinsuffizienz
KardiovaskulŠre PrŠvention / GUCH
KARAMBA (Kardiale Rehabilitation)
Kurzzeitklinik / Pflege / MTT / MTRA
Administration / Controlling
Outcome Forschung
Swiss-AF Cohort Study
Grundlagenforschung

03 Herzchirurgie 24 - 27

04 Notfallzentrum 28 - 29

05 Medizinische Intensivstation 30

06 KardioanŠsthesie 31

07 Operative Intensivbehandlung (OIB) 32 - 33

08 Lehre 34 - 35

09 Finanzielles 36 - 39
ForschungsbeitrŠge
Sponsoren / Gšnner

10 Publikationen Kardiologie / Herzchirurgie 40 - 51
Originalarbeiten
Reviews & Editorials
Letters to the editor
Case reports
Book chapters

11 Auszeichnungen
52 - 53

12 Kontakt
54

04 05
 01 Dienstleistungen

Dienstleistungen

 Leistungsstatistik Kardiologie UniversitŠtsspital
2016 2015 2014 2013

StationŠre Patienten 2'169 2'051 1'870 1'830

 Leistungsstatistik Kardiologie UniversitŠtsspital
Kardiologische Ambulatorien 2016 2015 2014 2013
Schrittmacherkontrollen 1'691 1'644 1'704 1'499
ICD-Kontrollen 1'649 1'514 1'757 1'774 Elektrokardiographie
Rhythmussprechstunde 452 398 403 458 Ruhe-EKG 1 15'082 11'473 12'127 12'028
Kardiologische AbklŠrungen 1'049 881 678 1'072 Langzeit-EKG Untersuchungen inkl. R-Tests 1'783 1'842 631 867
Herzinsuffizienz-Sprechstunde 547 547 460 423
LVAD-Kontrollen 45 n.a. n.a. n.a. Therapie
GUCH-Sprechstunde 130 122 123 128 Kardioversionen 228 208 165 176
Privatsprechstunden 1'304 1008 846 768 Schrittmacherimplantationen 304 283 273 237
Hypertonie Sprechstunde 1'001 813 730 547 Schrittmacherwechsel / Schrittmacherrevision 73 77 61 79
Rauchstopp Sprechstunde 758 541 497 286 Elektrodenentfernungen 29 15 19 20
Konsile 1'602 1'459 2'002 1'690 ICD-Implantationen 88 125 87 99
ICD-Wechsel / ICD-Revision 54 47 52 46
Spezialuntersuchungen CRT-ICD / CRT-PM 53 57 53 49
Linksherzkatheter 2'473 2'525 2'354 2'292 Ablationen 710 646 581 436
Rechtsherzkatheter 155 175 179 160 PTCA 1'278 1'279 1'193 1'130
Myokard-Biopsie 27 23 25 34 Mehrast-PTCA 387 422 364 286
Elektrophysiologische Untersuchungen 71 80 53 n.a. Sinus Coronarius Reduktion 6 n.a. n.a. n.a.
Echokardiographien, transthorakal 10'810 9'275 8'854 7'665 Valvuloplastien 1 1 2 3
Echokardiographien, transoesophageal 1'051 979 891 872 Verschluss eines ASD / PFO 33 27 47 39
Stressechokardiographien 220 145 123 64 Nicht operativer Aortenklappenersatz (TAVI) 131 103 107 99
24 h Blutdruckmessungen 1'224 1004 846 754 MitraClip 15 13 18 11
Somnotouch 296 137 n.a. n.a. Indirekte Mitralklappenannuloplastie 4 n.a. n.a. n.a.
Herz-MR 738 715 627 395 Renale Denervationen 1 1 n.a. 6
Herz-CT 356 232 277 572 Vorhofsohrverschluss 9 11 7 7
Ergometrien (inkl. Nuklearmedizin) 2'074 1'248 1'195 1'770 MVP 0 5 4 3
Spiroergometrien 84 72 83 96 ParavalvulŠrer Leckverschluss 2 n.a. n.a. 1
Myokardperfusionsszintigraphien 1'466 1'618 1'571 1'729 TASH 0 1 2 4
Herz-PET 55 n.a. n.a. n.a. Rehabilitation (KARAMBA) 331 389 363 284

06 07
 01 Dienstleistungen

Dienstleistungen

 Leistungsstatistik PartnerspitŠler  Leistungsstatistik Herzchirurgie UniversitŠtsspital
2016 2015 2014 2013 2016 2015 2014 2013

Bruderholzspital Prozeduren 1'098 1'031 1'157 1'267

Ruhe-EKG 10'385 11'539 10'936 2'708 Operationen mit Herz-Lungen-Maschine (HLM) 533 568 631 667
Langzeit-EKG (24-h) 547 633 553 582 Operationen ohne Herz-Lungen-Maschine (HLM) 121 101 112 95
R-Tests 54 38 34 47 Sonstige Operationen (Schrittmacher, ICD, Perikard, etc) 196 195 210 239
Ergometrien 454 340 329 364
Echokardiographie, transthorakal 1'942 1'948 1'917 1'773 Kombinationseingriffe (Herzoperationen mit HLM) 198 195 210 244
Echokardiographie, transoesophageal 72 83 93 81
Stressechokardiographie 22 25 23 27 Bypasschirurgie 313 345 417 449
Myokardperfusionsszintigraphie (in Zusammenar. m. Radiol.) 123 119 127 131 Aortokoronarer Bypass (AKB) isoliert mit HLM 168 208 234 250
MRI (in Zusammenarbeit mit Radiologie) 70 78 71 65 Aortokoronarer Bypass (AKB) ohne HLM ("OPCAB") 27 29 50 36
BD-Messung (24-h) 58 118 82 98 Kombinationseingriffe (AKB+) 116 110 132 163
Schrittmacherkontrollen inkl. ICD 726 828 828 783
Schrittmacherimplantationen inkl. -wechsel 62 67 72 81 Aortenklappenchirurgie 234 208 273 290
Kardioversionen 50 44 42 50 Aortenklappenersatz biologisch 127 119 167 170
StationŠre Konsilien 782 735 867 692 Aortenklappenersatz mechanisch 35 34 39 48
Aortenklappenrekonstruktion mit Eigenperikard (OP nach Ozaki) 15 8 n.a. n.a.
Aortenklappen- und Wurzelersatz ("Composite") 13 23 35 30
Service de Cardiologie Hopital du Jura Aortenklappenrekonstruktion 24 25 36 31
Transapikaler Aortenklappenersatz (ohne HLM, mit Kardiol.) 19 18 31 32
Ergometrien 125 136 174 108 AortoventrikulŠrer Bypass (AVB) 0 0 0 3
Echokardiographien, transthorakal 378 537 673 652
Echokardiographien, transoesophageal 8 4 13 15 Mitralklappenchirurgie 121 133 117 126
MRI 29 84 79 68 Mitralklappenersatz mit HLM 46 (43/3) 43 (40/3) 31 26
EKG 272 424 825 805 Mitralklappenrekonstruktion mit HLM 73 (33/40) 87 (43/44) 85 98
R-Test 5 12 9 10 Rekonstruktionsrate (geplant vs. durchgefŸhrt) 98% 97% n.a. n.a.
Schrittmacherimplantationen 4 31 24 29 Andere 2 3 n.a. 2
Schrittmacherwechsel 11 17 14 10
Schrittmacherkontrollen 171 374 340 317 Trikuspidal- und Pulmonalklappenchirurgie 12 16 15 20
ICD-Kontrollen 9 36 29 15 Trikuspidalklappenrekonstruktion 11 16 14 20
Holter 139 n.a. n.a. n.a. Pulmonalklappenersatz 1 0 1 0

08 09
 01 Dienstleistungen

Dienstleistungen

 Leistungsstatistik Herzchirurgie UniversitŠtsspital  Outcome Statistik
2016 2015 2014 2013
Zentraler Fokus bei den von der Kardiologie des USB angebo- sondern auch die Procedure-related Mortality ermittelt. Beides
tenen Leistungen ist die medizinische QualitŠt. Gerade in Zei- sind wichtige Messgršssen in der QualitŠtskontrolle, welche die
Operationen an der thorakalen Aorta 82 87 104 106
ten einer rasanten Entwicklung vor allem in technischen Berei- Kardiologie des USB seit mehreren Jahren transparent rappor-
chen der Medizin ist die exakte und lŸckenlose Aufarbeitung tiert.
Sonstige Eingriffe 48 50 53 51 von Komplikationen und TodesfŠllen, welche im Spital auftreten
Vorhofablation/Pulmonalvenenisolation 10 16 21 30 (In-hospital Mortality) von enormer Wichtigkeit. Im Rahmen der In der untenstehenden Tabelle sind alle TodesfŠlle aufgelistet, die
Vorhofseptumdefekt 38 34 32 21 QualitŠtskontrolle der Abteilung Kardiologie erfolgt eine syste- nach einer kardiologischen Intervention aufgetreten sind. Hierzu
matische Erfassung aller Eingriffe, welche im Laufe eines Jahres ist anzumerken, dass dabei auch TodesfŠlle rapportiert werden,
durchgefŸhrt werden. Basierend auf interdisziplinŠren Bespre- welche nicht kausal mit der Intervention zusammenhŠngen.
Extrakorporale Zirkulation (EKZ) 533 568 631 667
chungen im Rahmen von sogenannten Morbidity & Mortality Deshalb wird zusŠtzlich auch die procedure-related Mortality
Minimalisierte EKZ ("MECC") 146 196 232 231 Konferenzen (M&M) wird dabei nicht nur die In-hospital Mortality rapportiert.
Hypothermer Kreislaufstillstand 74 71 79 86

Kardiale UnterstŸtzungssysteme 49 61 53 57
Untersuchungstyp Anzahl In-hospital Tod Procedure-related Tod
Intraaortale Ballonpulsation (IABP) 28 42 31 37
Extrakorporale Membranoxygenation (ECMO) 21 19 22 19 Untersuchungen N (%) N (%)
LVAD (Destinationstherapie) 3 2 n.a. n.a.
PTCA / Stentimplantationen 1278 29 (2.3%) 4 (0.3%)
Eingriffsdringlichkeit Linksherzkatheter (ohne PTCA) 1195 28 (2.3%) 2 (0.2%)
Elektiv 567 504 530 573
Interventionelle Klappeneingriffe * 153 4 (2.6%) 2 (1.3%)
Notfall 154 135 89 94
Katheterablationen 710 2 (0.3%) 0
Dringlich 129 141 80 70
Schrittmacher-Implantationen 377 1 (0.3%) 0
Konsile Kardiologie 285 269 n.a. n.a. Schrittmacher-Wechsel/-revision
ICD-Implantationen 142 0 0
ICD-Wechsel/-revision
CRT-ICD / CRT-PM 53 0 0
Elektrodenextraktion 29 0 0
Rechtsherzkatheter 155 2 (1.3%) 0
Biopsie 27 1 (3.7%) 0
ASD/PFO-Verschluss 42 0 0

* TAVI (n=131, davon 112 transfemoral), Valvuloplastien der Aortenklappe oder Mitralklappe (AVP: n=1, MVP: n=0), Mitraclip (n=15),
indirekte Mitralklappenannuloplastie (n=4), Verschluss paravalvulŠres Leck (n=2)

10 11
 02 Kardiologie
Interventionelle Kardiologie
 Team
€rztliches Team
Prof. Christoph Kaiser
Prof. Raban Jeger
Prof. Peter Buser
Dr. G. Fahrni
Dr. R. Twerenbold
Dr. Bastian Wein
Wissenschaftliches Team
Dr. Nicole Gilgen
Andrea Harder-Allgšwer
Franziska Jordan
Margarete Baumgartner
12
Elektrophysiologie
 Team
€rztliches Team
Prof. Christian Sticherling
Prof. Stefan Osswald
PD Dr. Michael KŸhne
PD Dr. Tobias Reichlin
Prof. Beat SchŠr
Technisches Team
Dr. Sven Knecht
Florian Spies
Wissenschaftliches Team
Sarah Giesebart
Franziska Jordan
13
 02 Kardiologie

Echokardiographie Cardiac Imaging

 Team  Team

Aerztliche Mitarbeiter Echokardiographie Prof. Michael Zellweger

PD Dr. Beat Kaufmann Prof. Peter Buser
Prof. Michael Zellweger Dr. Thilo Burkard
PD Dr. Otmar Pfister Dr. Philip Haaf
PD Dr. Daniel Tobler
Dr. Arnheid Kessel Kollaboration mit Radiologie und Nuklearmedizin
Dr. Wanda Kloos
Dr. Jens Lohrmann
Dr. Frank-Peter Stephan

Mitarbeiter Cardiovascular Molecular Imaging

PD Dr. Beat Kaufmann
Dr. Amanda Ochoa-Espinosa
Dr. Mukesh Punjabi
Dr. Lifen Xu
David Steinl

14 15
 02 Kardiologie

Herzinsuffizienz KardiovaskulŠre PrŠvention / GUCH

 Team  Team KardiovaskulŠre PrŠvention/Hypertonie - Standort USB-MedPol

€rztliches Team Dr. Thilo Burkard

Prof. Christian MŸller
PD Dr. Otmar Pfister
Prof. Peter Rickenbacher
Prof. Peter Buser
PD Dr. Gabriela Kuster Pfister
Dr. Zaid Sabti
Wissenschaftliches Team
Salome RŸmmler
Franziska Jordan
Dr. Andrea Meienberg
Dr. Corinna KlŸber
Dr. Annina Vischer
Dr. Karsten Murray, AA (1.1.-31.3.16)
Dr. Firas Aldebssi, AA (1.6.-31.12.16)
Dr. Ruth Debenath A€ Medpol (1.1.-31.3.16)
Dr. Janina Ršhm, A€ Medpol (1.4.-30.9.16)
Dr. Martina Frick, A€ MedPol (1.10.-31.12.16)
Uta Engler
Nathalie Klaus

 Team GUCH

PD Dr. Daniel Tobler

Prof. Birgit Donner
Dr. Manuela Bernoulli A€ (01.10.2016-31.12.2016)
Dr. Sebastian Imhof AA (01.04.2016-30.06.2016)
Dr. Nicolas Kozhuharov AA (01.07.2016-30.09.2016)
Dr. Elena Lardi A€ (01.10.2016-31.12.2016)
Dr. Lukas Meier AA (1.1.2016-31.03.2016)
Lukas Notz
Gaby Frey

16 17
 02 Kardiologie

KARAMBA (Kardiale Rehabilitation) Kurzzeitklinik / Pflege / MTT / MTRA

 Team  Team KUK (Station 8.2)  Team MTRA

PD Dr. Otmar Pfister Susanne Timus Severine Dziergwa

Dr. Thilo Burkard Catherine Malgat Nadine Ruettener
Dr. Manuela Florence Bernoulli Prof. Christian MŸller Manuel Reidy
Dr. Cornelia Ganzoni Dr. Wanda Kloos Selina Botta
Andrea Iris Bannwart Dr. Jens Lohrmann Lea Burri
Antonia Candela (ab 01/2017) Stefan Devries
Livia Graf FrŠnzi Giger
Theresia Kohler  Team Pflege / MTT Barbara Imfeld
Julia LŠderach-Kaufmann Matthias Merz
Ruth Ostertag-Irniger Rosemarie BŸhrer Katja Obhues
Sarah Rigling Sšren Lorenz Christine Orsingher
Nicolas Rodriques (bis 12/2016) Nicole Kunst Salome Seppi
Monika Ršthlisberger-Dubach Bettina Andris (ab 01.06.16) Kathrin Waidele
Stephanie Ruch Norman BaumgŠrtel Gina Wietschorke
Yolanda Sanchez Bianca Behrendt (01.06.-31.07.16) Feride Yesilyayla
Fabienne Schneider Paul Blind
Madeleine Wick Annette Bus
Constance Deininger
Necla Demir (ab 01.08.16)
Klaus Peter Gunsch
Kathrin Hendrych (bis 29.02.16)
Antje Henke
Christina Huldi
Claudia Kernbach
Heidi Linder
Claudia Lutz
Daniele Minio
Andrea Mussler
Monika Schwager (bis 29.02.16)
Mandy Schwieger (bis 30.11.16
Brigitta Sorg
Kristina Valaityte
Brigitte Wiedmer
Alice Wingerdt

18 19
 02 Kardiologie 02 Kardiologie / Klinische Forschung

Administration / Controlling Outcome Forschung

 Team  Team

Arton Jusaj Prof. Danielle Menosi Gualandro Mustafa Assadian Deborah MŸller
Rocio Alvarez Dr. Ayman Alhussini Sara Barata Julian PfŠffli
Ela Ari Dr. Patrick Badertscher Patrick Bergsma Kristin Podkowik
Bilal Bektas Dr. Sanela Barac Dominik BreitenbŸcher Markus Riesterer
Gaby Frey Dr. Paul Jasper Boeddinghaus Sydney Corbire Therese Rinderknecht
Melanie Jost Dr. Ina-Maria Ferel-Harwrth Janosch Cupa Nicolas SchŠrli
Jolanda MŸller Dr. Ivana Dinclovic Jeanne du Fay de Lavallaz Deborah Schneider
Sarah Rigling Dr. Daniela Ernst Dayana Flores Widmer Aline Alessandra Schšni
Nicholas Rodriques Dr. Cornelia Ganzoni Michael Freese Marie Schubera
Aleksandra Schweizer Dr. Karin Grimm Natascha Herr Carmela Schumacher
Christina Schott Dr. Beate Hartmann Jonas Hilti Lukas Schumacher
Gaby Schwob Dr. Nikola Kozhuharov Ursina Honegger Daniela Seeberger
Sanja Trifkovic Dr. Caroline Kulangara Claudia Huck Claudia Stelzig
Ursula Vogt Dr. Riham Mahfouz Rahel Isenrich Ivo Strebel
Dr. Ewa Milopolska Irina Klimmeck Kathrin Luzia Thommen
Dr. Christian Puelacher Christine Kruse Devran TopyŸrek
Dr. Zaid Sabti Sabrina Laule Michael Tschuk
Dr. Samyut Shresta Nundsin Vanessa Lhasam Janine Všgele
Nathalie Rose, PhD Sarah Lšffel Fabian Vogt
Stella Marbot Joan Elias Walter
Patrick MŠchler Andres Zimmerli
Kathrin Meissner

20 21
21
 02 Kardiologie / Klinische Forschung 02 Kardiologie / Grundlagenforschung

Swiss-AF Cohort Study Cardio Biology

 Team  Team

Swiss-AF Cohort Study Prof. Marijke Brink, Forschungsleiterin

Prof. David Conen Christian Morandi, MSc
Prof. Stefan Osswald Lifen Xu, PhD
PD Dr. Michael KŸhne Sonia Lebboukh
Prof. Christian Sticherling Philippe Heim
Dr. Stefanie Aeschbacher Joseph Iharinjaka Randriamboavonjy, PhD (seit 9.16)
Dr. Steffen Blum
Dr. Philipp Krisai
Dr. Christiane Pudenz
Dr. Tobias Schšn
Dr. Anne Springer Myocardial Research
Laura Dšrig
Lucien Eggimann
Peter Egli  Team
Andreas Fischer
Rahel Kreuzmann PD Dr. Gabriela Kuster Pfister
Thomas Kofler PD Dr. Otmar Pfister
Pascal Meyre M. Sc. Vera Lorenz
Christoph Muff Dr. Lifen Xu
Andreas Reusser Dr. Michika Sato Mochizuki
Javier Ruperti M. Sc. Giacomo Della Verde
Gian Všllmin M. Sc. Daria Monogiou Belik

Molecular Imaging
 Team

PD Dr. Beat Kaufmann

Dr. Mukesh Punjabi
Dr. Lifen Xu
Dr. Amanda Ochoa-Espinosa
David Steinl

22 23
23
 03 Herzchirurgie

Klinik fŸr Herzchirurgie

 Team

€rzte Fachassistenten Herzchirurgie

Prof. Friedrich Eckstein Stefan Adamcik (seit 04/16)
PD Dr. Oliver Reuthebuch Dr. Prerana Banerjee (seit 06/16)
PD Dr. Martin Grapow Dr. Ludovic Melly (bis 02/16)
PD Dr. Denis Berdajs (seit 06/16) Myroslava Mytsyk (seit 04/16)
Prof. Dr. Peter Matt (bis 05/16) Dr. Jasmin Hasmik Shahinian
Dr. Florian RŸter Dr. Charlotte Wichmann (bis 06/16)
Dr. Ulrich Schurr
Rotationsassistenten Chirurgie
IMC Chirurgie Vladislav Borisov
Dr. Pierre Branitzki Marc-Antoine Burch
Dr. Clemens Dovifat Dr. Wolfgang Krickl
Dr. Karin Fuhrmann-Hilbrecht Witali Gorelow
Mairi Ziaka
Kerstin Buchholz (bis 06/16) Rotationsassistenten Kardiologie
Dr. Marc HŠfliger
Sebastian Kopp
Claudia Joha

Rotationsassistenten Innere Medizin

Christian Ansprenger
Dr. Jasper Bšddinghaus
Dr. Lara Hitz

24 25
 03 Herzchirurgie

Klinik fŸr Herzchirurgie

 Team

Kardiotechniker Sekretariat
Thomas Dšbele (Leitung) Jolanda Giess
Claudia Endres Miriam Boughalmi
Bejtush Rrahmani Laura Voegeli
Dr. Antoine Simons (seit 08/16) Petra Vocat
Urs Zenklusen Bettina Kohler

Forschungsgruppenteam
PD Dr. Anna Marsano
Giulia Cerino, PhD
Giuseppe Isu
Giuseppe Pisani
Emanuele Gaudiello, MSc
Thomas Grussenmeyer, PhD
Dietlinde John-Steinberg
Myroslava Mytsyk

Chirurgische Intermediate
Care Station (IMC)
Vitomir Jankovic
Manuela Buchacher

Chirurgische Station 4.1

Marcel Hentz
Stephanie Beyeler
Simon Scheifele
Karin Steiger

Chirurgische Station 7.1

Sibylle Waldmann
Silvia Violante

26 27
 04 Notfallzentrum

Notfallzentrum
 Team

€rzte Kader Administration

Prof. Dr. Roland Bingisser Monika Stadler
PD Dr. Christian Nickel Artur Stickel
Dr. Cristian Beca
Dr. Luc Blattmann
Dr. Nicolas Bless
Dr. Gerhard JŠckh
Dr. Gilbert KrŠhenbŸhl
Dr. Kriemhild Lippay
Dr. Gregory Mansella
Dr. Vera Pedersen
Dr. Manuel Puntschuh
Dr. Elisabeth Ratzenbšck
Dr. Christiane Rosin
Dr. Jochen RŸdiger
Dr. Eckehart Schšll
Dr. Sonia Shamdasani

Pflege Kader
Kathrin Matheis
Thorsten Althun
Thomas Dreher
Franziska Immboden
Kai LŸben
Ursula Neff

28 29
 05 Medizinische Intensivstation 06 KardioanŠsthesie

Medizinische Intensivstation KardioanŠsthesie

 Team  Team

€rzte €rzte
Prof. Stephan Marsch PD Dr. Jens Fassl
Prof. Patrick Hunziker PD Dr. Daniel Bolliger
Dr. Andres Christ Dr. Joachim Erb
Dr. Kai Tisljar
Dr. Markus Maurer
Dr. Gianmarco Balestra
Dr. David Heppel
Dr. Eva Hammel
Dr. Jorge Kasper Dr. Stefan Gisin
Dr. Heidi Lederer Dr. Andreas Lampart
Dr. Magnus Stalder Dr. Jonas Quitt
Dr. Karin Wildi Dr. Dominik Kallias

Pflege Pflegeteam
Angelika Lehmann Isabelle Gisler
Monika Strohmeier Elisabeth Goustiaux
Sabine Hiller Michael Gregor
Lukas Weibel
Christian Emsden
Marie-Noelle von Allmen

Sekretariat
Deborah Minnig

30 31
 07 Operative Intensivbehandlung (OIB)

Operative Intensivbehandlung (OIB)

 Team

€rzte
Prof. Dr. Hans Pargger
PD Dr. Martin Siegemund
Dr. Nadine Cueni
Dr. Jan Bittner
PD Dr. Andrea Kopp Lugli
Dr. Andreas LŸdin
Dr. Benjamin MŸller
Dr. Sarah Salvato
Dr. Patric Schlegel
Dr. Daniel Tuchscherer
Dr. Marianne Zumbrunn

Pflege
Michael Wehrli
Claudia Spychiger
Ursula Barandun SchŠfer
Conrad Wesch

Sekretariat
Janine Angliker

32 33
 08 Lehre
 Einsitz in Standesorganisationen

¥ Prof. C. Sticherling
Mitglied des Scientific Writing Committees der European Heart Rhythm Association (EHRA)

Lehre Past-PrŠsident der AG Herzschrittmacher und Elektrophysiologie der SGK

Mitglied der Tarifkommission der SGK
¥ Prof. M. Brink, Treasurer, PD Dr. med. Beat Kaufmann, Mitglied
SGK, Working Group of Cardiovascular Biology
 Weiter- und Fortbildungs-Veranstaltungen ¥ Prof. F. Eckstein
VizeprŠsident im Vorstand der Schweizerischen Gesellschaft fŸr Herz- und Thorakale GefŠsschirurgie
Externe Weiter- und Fortbildung ¥ PD Dr. B. Kaufmann
¥ Rhythmusvisite Kantonsspital Aarau 1 x Monat SGK, Working Group Echocardiogaphy and Cardiac Imaging, VizeprŠsident
¥ Regionale Fortbildungskurse (Rheinfelden / Bad Bubendorf) SGK Working Group Cardiovascular Biology, Board Member
Mitglied Tarifkommission der SGK
Interne Weiter- und Fortbildung ¥ Prof. C. Kaiser
¥ CCU-Rapport, tŠglich 08.00 Uhr Past-PrŠsident der Arbeitsgruppe Interventionelle Kardiologie der SGK
¥ Kardiologie, Montag 08.15 Uhr ¥ PD Dr. M. KŸhne
¥ Herzchirurgie, Montag 07.30-08.00 Uhr Ambassador for young electrophysiologists der EHRA (European Heart Rhythm Association)
¥ Departements Konferenz Chirurgie, Montag 08.10-9.00 Uhr ¥ PD Dr. G. Kuster Pfister
¥ Echokardiographie Fortbildung, Montag 12.30-13.30 Uhr Mitglied Fachgruppe Frau & Herz der Schweizerischen Herzstiftung
¥ Kardiochirurgisches und -medizinisches Meeting, Montag 17.00 Uhr ¥ Prof. Ch. MŸller
¥ Curriculum AA, Dienstag 7.45 Uhr Leiter, Dissertationsauszeichnungskommission der Medizinischen FakultŠt Basel
¥ Seminar KardiovaskulŠre Grundlagenforschung, 1x Monat, alternierend Mo 09.00-10.00 Uhr, bzw. Di 10:30-11:30 Uhr European Society of Cardiology, Acute Cardiovascular Care Association, Board Member
¥ Herzinsuffizienz Lunch, jeweils jeden dritten Dienstag im Monat 12.30-13.30 Uhr European Society of Cardiology, Heart Failure Association, Board Member
¥ Research-Lunch, alle 14 Tage, Dienstag 12.30-13.30 Uhr European Society of Cardiology, Biomarker Study Group, Member
¥ Kardiochirurgisches und -medizinisches Meeting, Mittwoch, 17.00 Uhr European Society of Cardiology, Acute Cardiovascular Care Association, Acute Heart FAilure Study Group, chair
¥ Kardio-Lunch, Donnerstag 12.30-13.30 Uhr European Society of Cardiology, Heart Failure Association, Committee on Diagnosis, chair
¥ Journal Club, Freitag 08.15-9.00 Uhr European Society of Cardiology, Heart Failure Association, Committee on Acute Heart Failure, member
¥ PCI-Lunch, 1 x Monat, Mittwoch/Freitag 12.20-13.30 Uhr GREAT Network, Vice president
¥ Rhythm and Pizza, 1 x Monat, Freitag 12.30-13.30 Uhr ¥ PD Dr. O. Pfister
¥ Mortality & Morbidity Conference, 1 x Monat, Freitag 12.30-13.30 Uhr Past President Arbeitsgruppe Herzinsuffizienz der Schweizerischen Gesellschaft fŸr Kardiologie
¥ Problemorientierte Fall Tutorate (2. Jahreskurs Medizinische FakultŠt Basel) ¥ PD Dr. O. Reuthebuch
¥ Arzt-Patienten-Unterricht (4. und 6. Jahreskurs Medizinische FakultŠt Basel) RechnungsprŸfer der Schweizerischen Gesellschaft fŸr Herzchirurgie
¥ PD Dr. D. Tobler
 Selbstorganisierte Kongresse / Symposien der Kardiologie Basel SGK, Vorstandsmitglied der Arbeitsgruppe fŸr Erwachsene und Jugendliche mit angeborenen Herzfehlern (WATCH)
¥ Prof. M. Zellweger
¥ medArt 2016, Juni 2016, Basel PrŠsident der SGK
¥ InteruniversitŠres GUCH-Kolloquium, September 2016
 Ausbildung
 Kongresse / Symposien mit Basler Hauptorganisation
¥ Prof. Marijke Brink:
¥ 18. Winter-Meeting, Swiss Working Group for Heart Failure, 21. - 23. Januar 2016, Grindelwald Themenblockleiterin: Themenblock Herz Kreislauf, 2. Bachelor Studienjahr
¥ Arrhythmia Summit 21.4.2016, Basel Themenblock Co-leiterin, 1. Master Studienjahr
¥ JournŽe de Biologie Paris, 22. - 24.06.2016 Physiologie-Professorin (Vorlesungen, Praktika, Tutoriate)
¥ GREAT Meeting Rom, September 2016 ¥ PD Dr. Grapow: Tutoriat 1. JK, Betreuung von 3 Master Studenten, Betreuung von 1 Doktorandin
¥ "New Swiss Horizon" Electrophysiology-meeting Lenzerheide, 23./24.09.2016 ¥ PD Dr. Reuthebuch: Betreuung von 2 Master Studenten
¥ DreilŠndertreffen Herzinsuffizienz Halle an der Saale, 19. - 21. Oktober 2016 ¥ PD Dr. Reichlin: OSCE Staatsexamen
¥ EKG Kurs fŸr Assistenten, 27./28.10.2016, Luzern ¥ Prof. Christian MŸller: Betreuung von 10 Masterstudenten / Tutoriat 4. JK / Betreuung von 14 Doktoranden
¥ EHRA Education Program for Physisicans- Implantable Cardioverter Defibrillator Module, Berlin, 17.-18.11.2016 ¥ Prof. SchŠr: Themenblockorganisator
¥ Prof. Sticherling, Prof. Osswald, Prof. SchŠr, PD Dr. KŸhne: Vorlesungen
¥ Prof. Sticherling, Prof. Osswald, Prof. SchŠr, PD Dr. KŸhne, PD Dr. Reichlin: EKG Kurs
34 35
 09 Finanzielles

Finanzielles
 ForschungsbeitrŠge  Schweizerische Herzstiftung

 Schweizer Nationalfonds ¥ Rubini-G. M: Addressing gender-specific inequalties in the early diagnosis and management of acute cardiovascular diseases
Beginn: 01.11.2016 / 1 Jahr
¥ SNF Projektfšrderung 310030_149718: Kaufmann B. ¥ MŸller C.: Advantageous predictors of acute coronary syndromes evaluation (APACE, Phase III)
Non-invasive ultrasound molecular imaging of myocarditis and autoimmune myocardial inflammation Beginn: 01.11.2016 / 1 Jahr
Beginn: 01.04.2014 / 3 Jahre
¥ SNF Professur Nr: PP00P3_133681: Conen D.:
Risk factors and outcomes associated with the progression of human atrial fibrillation:  KTI
Role of Inflammation, Oxidative Stress and Fibrosis in the Initiation and Progression of Human Atrial Fibrillation: 2011-2016
Beginn: 01.07.2011 / 5 Jahre ¥ Projektfšrderung: MŸller C.
¥ SNF Projektfšrderung 310030-169996: Brink M Nicht-invasive Diagnose der koronaren Herzerkrankung:
"Gender-specific mechanisms of cardiac dysfunction in obesity" Innovative Anwendung von Biomarkern und EKG-Signalen
Beginn 01.10.2016 / 3 Jahre Beginn: 01.07.2014 / 2 Jahre
¥ SNF Projektfšrderung 33IC30_166855/1: Tobler D.
Effect of phosphodiesterase-5 inhibition with tadalafil on systemic right ventricular function � a multi-center, double-blind-
randomized, placebo-controlled clinical trial  Stiftung fŸr kardiovaskulŠre Forschung Basel
Beginn: 01.01.2016 / 5 Jahre
¥ SNF Projektfšrderung 156953: Kuster G./Pfister O. ¥ Brink M., Conen D., Jeger R., Kaiser C., Kaufmann B., Kuster Pfister G., MŸller C., Pfister O., Sticherling C., Zellweger M.
Regulators of cardiac progenitor cells: Focus on cancer drug targets
Beginn / Dauer: 1.1.2016 / 3 Jahre
¥ SWISS-AF (Longitudinal Studies): 33CS30_148474: Conen D., Osswald S.  ForschungsbeitrŠge UniversitŠt Basel
Swiss Atrial Fibrillation Cohort Study
Beginn: 01.03.2014 / 4 Jahre ¥ Kuster G.: Molecular mechanisms of matrix-instructed cardiac progenitor cell fate
¥ SNF Projektfšrderung Nr. 32003B_159495/1: MŸller C. APACE Validation Beginn / Dauer: 1.1.2016 / 1 Jahr
Beginn: 01.01.2016 / 3 Jahre

 EU-Grants

¥ 2013 European Union FP7-Health_2013_Innovation 1 (Project 602299): Sticherling C.

EU-CERT-ICD Comparative effectiveness research to assess the use of primary prophylactic implantable cardioverter
defibrillators in Europe
Beginn: 1.10.2013 / 4 Jahre

¥ Eurostars: "E!9799 ALVALE: Tobias Reichlin

Anatomical Localization of the origin of Ventricular Arrhythmias from the 12-Lead ECG"
Beginn: 1.1.16 / 1,5 Jahre

36 37
 09 Finanzielles

Finanzielles
 Andere Quellen / Stiftungen  Sponsoren und Gšnner

¥ Swiss Life AG JubilŠumsstiftung ¥ Abbott AG ¥ Medtronic (Schweiz) AG

G. Kuster: Impact of Flt3-disruption on cardiac progenitor cell homeostasis and function: Implications for cancer therapy-related ¥ Actelion Schweiz ¥ mepha
cardiotoxicity ¥ A. Menarini AG ¥ Merck Sharp & Dohme
Beginn / Dauer: 1.1.2015 / 2 Jahre ¥ AstraZeneca AG ¥ Mundipharma Medical Company
¥ Goldschmidt-Jacobsen-Stiftung
¥ Bayer (Schweiz) AG ¥ Novartis AG
T. Reichlin: Refinement and Integration of Advanced ECG Technologies in Clinical Cardiology
¥ Biosense Webster ¥ novo nordisk
Beginn / Dauer: 1.4.2015 / 3 Jahre
¥ Biotronik Schweiz AG ¥ Nycomed Pharma AG
¥ Boehringer Ingelheim ¥ Pfizer AG
 Andere Quellen / Industrie ¥ Boston Scientific ¥ Robapharm AG
¥ B.R.A.H.M.S. GmbH ¥ Roche
¥ Abbott: ¥ B. Braun Melsungen AG ¥ Sandoz Pharmaceuticals AG
Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.) ¥ BŸhlmann Laborator AG ¥ Sanofi Aventis SA
BASEL VIII (MŸller C) ¥ concile ¥ Schwabe Pharma AG
¥ BASEL-PMI (MŸller C) ¥ Cordis Johnson & Johnson ¥ Sigma-Tau Pharma AG
¥ Beckman Coulter: ¥ Daiichi Sankyo (Schweiz) AG ¥ Stentys
APACE (MŸller C) ¥ 8sens biognostics GmbH ¥ Stiftung fŸr kardiovaskulŠre Forschung Basel
¥ Biomerieux: ¥ Edwards Life Science AG ¥ St. Jude Medical (Schweiz) AG
Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.)
¥ Eli Lilly (Suisse) SA ¥ Sorin
¥ BRAHMS:
¥ Fšrderverein Kardiologie Basel ¥ Swiss Life AG
Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.)
BASEL IX - Basel Syncope Evaluation Study (MŸller C.) ¥ GlaxoSmithKline AG ¥ Takeda Pharma AG
BASEL V - Acute dyspnea (MŸller C.) ¥ GrŸnenthal Pharma AG ¥ Terumo
¥ B. Braun Melsungen AG: ¥ Guidant Europe SA ¥ The Medicines Company
BASKET-SMALL 2-Studie (Jeger R.) ¥ IBSA ¥ Vifor Pharma
¥ Roche: ¥ J.C. General Serv. CVBA ¥ Viollier AG
Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.) ¥ Johnson & Johnson
BASEL V - Acute dyspnea (MŸller C.)
GALACTIC (MŸller C.)
¥ Siemens:
Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.)
¥ Singulex:
Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.)
BASEL VII - Acute Abdominal Pain (MŸller C.)
Biochemical and electrocardiographic signatures to detect exercise-induced myocardial ischemia (MŸller C.)
BASEL V, BASEL VIII, BASEL IX (MŸller C.)

38 39
 10 Publikationen
Publikationen
 Originalarbeiten
1. Aeschbacher S, Bossard M, Ruperti Repilado FJ, Good N, Schoen T,
Zimny M, Probst-Hensch NM, Schmidt-TrucksŠss A, Risch M, Risch L,
Conen D. Healthy lifestyle and heart rate variability in young adults. Eur
J Prev Cardiol. 2016;23(10):1037-44. Impact Factor 3.361
2. Aeschbacher S, Bossard M, Schoen T, Schmidlin D, Muff C, Maseli
A, Leuppi JD, Miedinger D, Probst-Hensch NM, Schmidt-TrucksŠss A,
Risch M, Risch L, Conen D. Heart rate variability and sleep-related brea-
thing disorders in the general population. Am J Cardiol 2016;118(6):912-
7. Impact Factor 3.154
3. Aeschbacher S, Schoen T, Dšrig L, Kreuzmann R, Neuhauser C, Schmidt-
TrucksŠss A, Probst-Hensch NM, Risch M, Risch L, Conen D. Heart rate,
heart rate variability and inflammatory biomarkers among young and
healthy adults. Ann Med 2016: Epub ahead of print. Impact Factor 3.763
4. Aeschbacher S., Metin F., Bossard M., Schoen T., von Rotz M., Mettler
H., AbŠcherli R., Risch M., Risch L., Conen D. Relationships of electro-
cardiographic parameters with ambulatory hypertension in young and
healthy adults. Int J Cardiol 2016; 202:300-304. Impact Factor 4.638
5. Aimo A., Vergaro G., Ripoli A., Bayes Genis A., Pascual-Figal D.A., De
Boer R., Lassus J., Mebazaa A., Gayat E., Breidthardt T., Sabti Z., Mueller
C., Tang W., Grodin J.L., Zhang Y., Bettencourt P., Maisel A.S., Januzzi
J.L., Emdin L. Prognostic value of soluble suppression of tumorigenici-
ty-2 (sST2) in acute heart failure: a meta-analysis. JACC Heart Failure
2016 in press. Impact Factor 7
6. Asgar A, Chandrasekhar J, Mikhail G, Webb J, Lefvre T, Tamburino C,
Hildick-Smith D, Hambrecht R, Van Belle E, Widder J, Dumonteil N, Hink
U, Jeger R, Linke A, Deliargyris E, Gao P, Mehran R, Hengstenberg C,
Anthopoulos P, Dangas G; BRAVO-3 Investigators. Sex-based differen-
ces in outcomes with bivalirudin or unfractionated heparin for transca-
theter aortic valve replacement: Results from the BRAVO-3 randomized
trial. Catheter Cardiovasc Interv. 2016 May 6. doi: 10.1002/ccd.26607.
[Epub ahead of print] Impact Factor 2.181
7. Baber U, Giustino G, Sartori S, Aquino M, Stefanini GG, Steg PG,
Windecker S, Leon MB, Wijns W, Serruys PW, Valgimigli M, Stone GW,
Dangas GD, Morice MC, Camenzind E, Weisz G, Smits PC, Kandzari D,
Von Birgelen C, Mastoris I, Galatius S, Jeger RV, Kimura T, Mikhail GW,
Itchhaporia D, Mehta L, Ortega R, Kim HS, Kastrati A, Chieffo A, Mehran
R.Effect of Chronic Kidney Disease in Women Undergoing Percutaneous
Coronary Intervention With Drug-Eluting Stents: A Patient-Level Pooled
Analysis of Randomized Controlled Trials. JACC Cardiovasc Interv. 2016
Jan 11;9(1):28-38. doi: 10.1016/j.jcin.2015.09.023. Impact Factor 7.630
40
8. Bel M, Panteghini M, Plebani M, Verschuren F, Jernberg T, French JK,
Christenson RH, Body R, McCord J, Dilba P, Katus HA, Mueller C; for the
TRAPID-AMI Investigators. Age- and Gender-specific Compared to Gene-
ral 99th Percentile Cut-offs for Diagnosis of Myocardial Infarction and Pro-
gnostic Implications -Sub-analysis from the TRAPID-AMI (High-sensitivity
cardiac Troponin T assay for RAPID rule-out of Acute Myocardial Infarc-
tion) Study. Int J Cardiol. 2016; Apr 15;209:26-33. Impact Factor 4.638
9. Beri N., Marston N.A., Daniels L.B., Nowak R.M., Schreiber D., Muel-
ler C., Jaffe A., Diercks D.B., Wettersten N., DeFilippi C., Peacock W.F.,
Limkakeng A.T., Anand I., McCord J., Hollander J.E., Wu A.H., Apple
F.S., Nagurney J.T., Berardi C., Cannon C.M., Clopton P., Neath S.X.,
Christenson R.H., Hogan C., Vilke G., Maisel A. Necessity of hospitaliza-
tion and stress testing in low risk chest pain patients. Am J Emerg Med.
2016 Oct 29. Epub ahead of print. Impact Factor 2
10. Boccardo S, Gaudiello E, Melly L, Cerino G, Ricci D, Martin I, Eckstein
F, Banfi A, Marsano A. Engineered mesenchymal cell-based patches as
controlled VEGF delivery systems to induce extrinsic angiogenesis. Acta
Biomater. 2016 Sep 15;42:127-35. doi: 10.1016/j.actbio.2016.07.041.
Epub 2016 Jul 25. Impact Factor 6.008
11. Body R, Mueller C, Giannitsis E, Christ M, Ordonez-Llanos J, de Fi-
lippi CR, Nowak R, Panteghini M, Jernberg T, Plebani M, Verschuren F,
French JK, Christenson R, Weiser S, Bendig G, Dilba P, Lindahl B; for the
TRAPID-AMI Investigators. The use of very low levels of high sensitivity
troponin T to rule out acute myocardial infarction using a single blood
test. Acad Emerg Med J. 2016; Sep;23(9):1004-13. Impact Factor 3.0
12. Boeddinghaus J, Reichlin T, Cullen L, Greenslade JH, Parsonage WA,
Hammett C, Pickering JW, Hawkins T, Aldous S, Twerenbold R, Wildi
K, Nestelberger T, Grimm K, Rubini Gimenez M, Puelacher C, Kern V,
Rentsch K, Than M, Mueller C. Two-Hour Algorithm for Triage Towards
Rule-Out and Rule-In of Acute Myocardial Infarction by Use of High-
Sensitivity Cardiac Troponin I. Clin Chem. 2016; Mar;62(3):494-504. Im-
pact Factor 7.911
13. Bolliger D, Filipovic M, Matt P, Tanaka KA, Gregor M, Zenklusen
U, Seeberger MD, Lurati Buse G. Reduced aspirin responsiveness as
assessed by impedance aggregometry is not associated with adver-
se outcome after cardiac surgery in a small low-risk cohort. Platelets.
2016;27(3):254-61. Impact Factor 3.213
14. Bossard M, Kreuzmann R, Hochgruber T, Krisai P, Zimmermann AJ,
Aeschbacher S, Pumpol K, Kessel-Schaefer A, Stephan FP, Handschin N,
Sticherling C, Osswald S, Kaufmann BA, ParŽ G, KŸhne M, Conen D. De-
terminants of Left Atrial Volume in Patients with Atrial Fibrillation. PLoS
One. 2016 Oct 4;11(10):e0164145. doi: 10.1371/ journal. pone. 0164145.
Impact Factor 4.411
15. Bossard M, ThŽriault S, Aeschbacher S, Schoen T, Kunz S, von Rotz
M, Estis J, Todd J, Risch M, Mueller C, Risch L, ParŽ G, Conen D. Factors
independently associated with cardiac troponin I levels in young and
healthy adults from the general population. Clin Res Cardiol 2016;Epub
ahead of print. Impact Factor 4.324
16. Breidthardt T., Moreno Weidmann Z., Twerenbold R., Gantenbein
C., Stallone F., Rentsch K., Rubini Gimenez M., Kozhuharov N., Sabti
Z., BreitenbŸcher D., Wildi K., Puelacher C., Honegger U., Wagener M.,
Schumacher C., Hillinger P., Osswald S., Mueller C. Impact of Haemo-
concentration during Acute Heart Failure Therapy on Mortality and its
Relationship with Worsening Renal Function. Eur J Heart Fail 2016; Oct
19. doi: 10.1002/ejhf.667. [Epub ahead of print. Impact Factor 5.135
17. Brenner R, Ammann P, Yoon SI, Christen S, Hellermann J, Girod G,
Knaus U, Duru F, Krasniqi N, Ramsay D, Sticherling C, Lippuner, KŸhne
M. Reduction of falls and fractures after permanent pacemaker implan-
tation in elderly patients with sinus node dysfunction. Europace 2016 (in
press). Impact Factor 4.021
18. Brown J.R., Pearlman D.M, Marshall E., MacKenzie T.A., Recio-May-
oral A., Gomes V.O.,Kim B., Jensen L.O., Mueller C., Maioli M., Solomon
R.J. Individual Patient Data Meta-Analysis of Sodium Bicarbonate versus
Sodium Chloride for All-Cause Mortality After Coronary Angiography.
Am J Cardiol 2016; Nov 15;118(10):1473-1479. Impact Factor 3.154
19. Celikyurt U, Knecht S, Kuehne M, Reichlin T, Muehl A, Osswald S, Sti-
cherling C. Incidence of new-onset atrial fibrillation after cavotricuspid isth-
mus ablation for atrial flutter. Europace 2016 (in press). Impact Factor 4.021
20. Cerino G, Gaudiello E, Grussenmeyer T, Melly L, Massai D, Banfi A,
Martin I, Eckstein F, Grapow M, Marsano A. Three dimensional multi-
cellular muscle-like tissue engineering in perfusion-based bioreactors.
Biotechnol Bioeng. 2016 Jan;113(1):226-36. Impact Factor 4.243
21. Chapman A., Anand A., Boeddinghaus J., Ferry A., Sandeman D.,
Adamson P., Andrews J., Tan S., Cheng S., D‘Souza M., Orme K., Stra-
chan F., Nestelberger T., Twerenbold R., Badertscher P., Reichlin T., Gray
A., Shah A., Mueller C., Newby D., Mills N. Comparison of the efficacy
and safety of early rule out pathways for acute myocardial infarction.
Circulation 2016; in press. Impact Factor 17.202
22. Christ Michael, Stefan Stšrk, Marcus Dšrr, Hans J. Heppner, Chris-
tian MŸller, Rolf Wachter, and Uwe Riemer for the Trend HF Germany
Project. Heart failure epidemiology 2000–2013: insights from the Ger-
man Federal Health Monitoring System Eur J Heart Fail 2016; in press.
Impact Factor 5.135
23. Conen D, Arendacká B, Ršver C, Bergau L, Munoz P, Wijers S, Sti-
cherling C, Zabel M, Friede T. Gender differences in appropriate shocks
and mortality among patients with primary prophylactic implantable
cardioverter-defibrillators: Systematic review and meta-analysis. PLoS
One 2016; 11(9): e0162756. Impact Factor 4.411
24. Conen D, Wong JA, Sandhu RK, Cook NR, Lee IM, Buring JE, Albert
CM. Risk of malignant cancer among women with new-onset atrial fib-
rillation. JAMA Cardiol 2016;1:389-396.
25. De Maria GL, Fahrni G, Alkhalil M, Cuculi F, Dawkins S, Wolfrum
M, Choudhury RP, Forfar JC, Prendergast BD, Yetgin T, van Geuns RJ,
Tebaldi M, Channon KM, Kharbanda RK, Rothwell PM, Valgimigli M,
Banning AP. A tool for predicting the outcome of reperfusion in ST-
elevation myocardial infarction using age, thrombotic burden and index
of microcirculatory resistance (ATI score). EuroIntervention. 2016 Nov
20;12(10):1223-1230. Impact Factor 3.863
26. De Maria GL, Patel N, Wolfrum M, Fahrni G, Kassimis G, Porto I,
Dawkins S, Choudhury RP, Forfar JC, Prendergast BD, Channon KM,
Kharbanda RK, Garcia-Garcia HM, Banning AP. The influence of coronary
plaque morphology assessed by optical coherence tomography on final
microvascular function after stenting in patients with ST-elevation myo-
cardial infarction. Coron Artery Dis. 2016 Dec 6. [Epub ahead of print]
Impact Factor 1.553
27. Dobson L.E., Musa T.A., Uddin A., Fairbairn T.A., Swoboda P.P., Er-
hayiem B., Foley J., Garg P., Haaf P., Fent G.J., Malkin C.J., Blackman
D.J., Plein S., Greenwood J.P. Acute Reverse Remodelling After Transca-
theter Aortic Valve Implantation: A Link Between Myocardial Fibrosis and
Left Ventricular Mass Regression. Can J Cardiol. 2016 Dec;32(12):1411-
1418. doi: 10.1016/j.cjca.2016.04.009. PMID:27523272. Impact Factor
3.112
28. Eser P, Herzig D, Vogt M, StŠmpfli R, Trovato M, Olstad DS, Trachsel
L, Deluigi C, Wustmann K, Greutmann M, Tobler D, Stambach D, Schmid
JP, Schwerzmann M, Wilhelm M. Vagal reactivation after exercise and
cardiac autonomic nervous activity in adult Fontan patients without pace-
makers Int J Cardiol. 2016 Jun 28;220:527-533. Impact Factor 4.638
29. Fahrni G, Wolfrum M, De Maria GL, Banning AP, Benedetto U, Khar-
banda RK. Prolonged High-Dose Bivalirudin Infusion Reduces Major Blee-
ding Without Increasing Stent Thrombosis in Patients Undergoing Prima-
ry Percutaneous Coronary Intervention: Novel Insights From an Updated
Meta-Analysis. J Am Heart Assoc. 2016 Jul 22;5(7). Impact Factor 4.306
41
 10 Publikationen
Publikationen
30. Ferko N, Ferrante G, Hasegawa JT, Schikorr T, Soleas IM, Hernandez
JB, SabatŽ M, Kaiser C, Brugaletta S, de la Torre Hernandez JM, Galatius
S, Cequier A, Eberli F, de Belder A, Serruys PW, Valgimigli M. Cost-effec-
tiveness of percutaneous coronary intervention with cobalt-chromium
everolimus eluting stents versus bare metal stents: Results from a pati-
ent level meta-analysis of randomized trials. Catheter Cardiovasc Interv.
2016 Aug 16 [Epub ahead of print]. Impact Factor 2.181
31. Ferreira JP, Girerd N, Arrigo M, Bettencourt Medeiros P, Bento Ri-
cardo M, Almeida T, Rola A, Tolpannen H, Laribi S, Gayat E, Mebazaa
A, Mueller C, Zannad, F, Rossignol P, Araga˜o I. Enlarging Red Blood
Cell Distribution Width During Hospitalization Identifies a Very High-Risk
Subset of Acutely Decompensated Heart Failure Patients and Adds Va-
luable Prognostic Information on Top of Hemoconcentration. Medicine
2016;95: (14):e3307. Impact Factor 2.133
32. Forni Ogna V, Ogna A, Ponte B, Gabutti L, Binet I, Conen D, Erne P,
Gallino A, Guessous I, Hayoz D, Muggli F, Paccaud F, PŽchre-Bertchi
A, Suter PM, Bochud M, Burnier M. Prevalence and determinants of
chronic kidney disease in the Swiss population. Swiss Med Wkly
2016;146:w14313. Impact Factor 1.549
33. Franzone A, Taniwaki M, Rigamonti F, Heg D, Piccolo R, Roffi M,
TŸller D, Muller O, Vuilliomenet A, Cook S, Weilenmann D, Kaiser C,
Jamshidi P, JŸni P, Windecker S, Pilgrim T. Angiographic complexi-
ty of coronary artery disease according to SYNTAX score and clinical
outcomes after revascularisation with newer-generation drug-eluting
stents: a substudy of the BIOSCIENCE trial. EuroIntervention. 2016 Aug
5;12:e595-604. Impact Factor 3.863
34. Freiermuth D, Mets B, Bolliger D, Reuthebuch O, Doebele T, Scholz
M, Gregor M, Haschke M, Seeberger MD, Fassl J. Sevoflurane and Iso-
flurane-Pharmacokinetics, Hemodynamic Stability, and Cardioprotective
Effects During Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth.
2016 Dec;30(6):1494-1501. doi: 10.1053/j.jvca.2016.07.011. Impact
Factor 1.519
35. Garg P., Kidambi A., Swoboda P.P., Foley J.R., Musa T.A., Ripley
D.P., Erhayiem B., Dobson L.E., McDiarmid A.K., Fent G.J., Haaf P.,
Greenwood J.P., Plein S. The role of left ventricular deformation in the
assessment of microvascular obstruction and intramyocardial haemor-
rhage. Int J Cardiovasc Imaging. 2016 Oct 26. [Epub ahead of print]
PMID:27785677. Impact Factor 1.880
42
36. Giustino G, Baber U, Aquino M, Sartori S, Stone GW, Leon MB, Ge-
nereux P, Dangas GD, Chandrasekhar J, Kimura T, Salianski O, Stefanini
GG, Steg PG, Windecker S, Wijns W, Serruys PW, Valgimigli M, Morice
MC, Camenzind E, Weisz G, Smits PC, Kandzari DE, Galatius S, Von
Birgelen C, Saporito R, Jeger RV, Mikhail GW, Itchhaporia D, Mehta L,
Ortega R, Kim HS, Kastrati A, Chieffo A, Mehran R. Safety and Efficacy
of New-Generation Drug-Eluting Stents in Women Undergoing Complex
Percutaneous Coronary Artery Revascularization: From the WIN-DES
Collaborative Patient-Level Pooled Analysis. JACC Cardiovasc Interv.
2016 Apr 11;9:674-84 Impact Factor 7.630
37. Giustino G, Mastoris I, Baber U, Sartori S, Stone GW, Leon MB, Ser-
ruys PW, Kastrati A, Windecker S, Valgimigli M, Dangas GD, Von Bir-
gelen C, Smits PC, Kandzari D, Galatius S, Wijns W, Steg PG, Stefanini
GG, Aquino M, Morice MC, Camenzind E, Weisz G, Jeger RV, Kimura
T, Mikhail GW, Itchhaporia D, Mehta L, Ortega R, Kim HS, Chieffo A,
Mehran R Correlates and Impact of Coronary Artery Calcifications in Wo-
men Undergoing Percutaneous Coronary Intervention With Drug-Eluting
Stents: From the Women in Innovation and Drug-Eluting Stents (WIN-
DES) Collaboration. JACC Cardiovasc Interv. 2016 Sep 26;9(18):1890-
901 Impact Factor 7.630
38. Haude M, Ince H, Abizaid A, Toelg R, Lemos PA, von Birgelen C,
Christiansen EH, Wijns W, Neumann FJ, Kaiser C, Eeckhout E, Lim ST,
Escaned J, Garcia-Garcia HM, Waksman R. Safety and performance of
the second-generation drug-eluting absorbable metal scaff old in pati-
ents with de-novo coronary artery lesions (BIOSOLVE-II): 6 monthresults
of a prospective, multicentre, non-randomised, first-in-man trial. Lancet.
2016;31-9. Impact Factor 44.002
39. Haude M, Ince H, Abizaid A, Toelg R, Lemos PA, von Birgelen C,
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97. Satalkar P, Elger BS, Hunziker P, Shaw D. Challenges of clinical trans-
lation in nanomedicine: a qualitative study. Nanomedicine 2016. Impact
Factor 4.889
98. Schaer B, Frey S, Sticherling C, Osswald S, Reichlin T, KŸhne M. Per-
sistent improvement of ejection fraction in patients with a cardiac resyn-
chronization therapy defibrillator correlates with fewer appropriate ICD
interventions and lower mortality. Swiss Med Wkly 2016; 146:w14300.
Impact Factor 1.549
99. Schaer B, KŸhne M, Reichlin T, Osswald S, Sticherling C. Incidence of
and predictors for appropriate implantable cardioverter-defibrillator thera-
py in patients with a secondary preventive implantable cardioverter-defib-
rillator indication. Europace. 2016 Feb;18(2):227-31. Impact Factor 4.021
100. Seegers, J. Conen D., Jung K., Bergau L., Dorenkamp M., LŸthje L.,
Sohns C., Sossalla S.T., Fischer T.H., Hasenfuss G., Friede T., Zabel M..
Sex difference in appropriate shocks but not mortality during long-term
follow-up in patients with implantable cardioverter-defibrillators. Euro-
pace 2016;18:1194-1202. Impact Factor 4.021
101. Shende P, Xu L, Morandi C, Pentassuglia L, Heim P, Lebboukh S,
Berthonneche C, Pedrazzini T, Kaufmann BA, Hall MN, RŸegg MA, Brink
M.Cardiac mTOR complex 2 preserves ventricular function in pressure-
overload hypertrophy. Cardiovasc Res. 2016;109(1):103-14. Impact Fac-
tor 5.465
102. Shulga D, Morozov O, Hunziker P. A Tensor B-Spline Approach for
Solving the Diffusion PDE With Application to Optical Diffusion Tomogra-
phy. IEEE Transactions on Medical Imaging 2016. Impact Factor 3.756
103. Silvetti S, Crivellari M, Castiglioni A, Landoni G, Zangrillo A, Alfi-
eri O, Koster A, Faraoni D, Bolliger D, Tanaka KA. CASE 12-2016 As-
cending Aorta Dissection in a Jehovah‘s Witness Patient on Warfarin.
J Cardiothorac Vasc Anesth. 2016 Dec;30(6):1709-1715. doi: 10.1053/j.
jvca.2016.02.029. No abstract available. Impact Factor 1.519
104. Sou SM, Puelacher C, Twerenbold R, Wagener M, Honegger U,
Reichlin T, Schaerli N, Pretre G, AbŠcherli R, Jaeger C, Rubini Gimenez
M, Wild D, Rentsch KM, Zellweger MJ, Mueller C. Direct comparison of
cardiac troponin I and cardiac troponin T in the detection of exercise-
induced myocardial ischemia. Clinical Biochemistry 2016 Apr;49(6):421-
32. Impact Factor 2.382
105. Staempfli R, Schmid JP, Schenker S, Eser P, Trachsel LD, Delu-
igi C, Wustmann K, Thomet C, Greutmann M, Tobler D, Stambach D,
Wilhelm M, Schwerzmann Cardiopulmonary adaptation to short-term
high altitude exposure in adult Fontan patients M. Heart 2016;0:1-6.
doi:10.1136/heartjnl-2016-309682. Impact Factor 5.693
106. Stallone F, Schoenenberger AW, Puelacher C, Rubini Gimenez M,
Walz B, Naduvilekoot Devasia A, Bergner M, Twerenbold R, Wildi K,
Reichlin T, Hillinger P, Erne P, Mueller C. Incremental value of copep-
tin in suspected acute myocardial infarction very early after symp-
tom onset. Eur Heart J Acute Cardiovasc Care 2016 2016 Mar 24. pii:
2048872616641289.
107. Staub D, Partovi S, Zeller T, Breidthardt T, Kaech M, Boeddinghaus
J, Puelacher C, Nestelberger T, Aschwanden M, Mueller C. Multimarker
Assessment for the Prediction of Renal Function Improvement After Per-
cutaneous Revascularization for Renal Artery Stenosis. Cardiovascular
Diagnosis and Therapy 2016; in press.
108. Steinl M, Xu L, Khanicheh E, Ellertsdottir E, Ochoa-Espinosa A, Mit-
terhuber M, Glatz K, Kuster GM, Kaufmann BA. Non-invasive contrast
enhanced ultrasound molecular imaging detects myocardial inflamm-
atory response in autoimmune myocarditis. Circ Cardiovasc Imaging.
2016 Aug;9(8). pii: e004720. Impact Factor 5.744
109. Sticherling C, Menafoglio A, Burri H, ReeK S, Fuhrer J, GaniŽre V,
Zimmerli M, Babotai I, Duru F, Pruvot E, Seeberger M, Kindler C, Basciani
R, Vogt A, Eberle B, Marcucci C, Ecknauer E, Bollinger D. Recommenda-
tions for the perioperative management of patients with cardiac implan-
table devices. Cardiovasc Med 2016;19:13-18.
110. Swoboda P.P., McDiarmid A.K., Erhayiem B., Haaf P., Kidambi A.,
Fent G.J., Dobson L.E., Musa T.A., Garg P., Law G.R., Kearney M.T., Barth
J.H., Ajjan R., Greenwood J.P., Plein S. A Novel and Practical Screening
Tool for the Detection of Silent Myocardial Infarction in Patients With
Type 2 Diabetes. J Clin Endocrinol Metab. 2016 Sep;101(9):3316-23. doi:
10.1210/jc.2016-1318. PMID:27300573. Impact Factor 5.531
111. Tolppanen H, Siirila-Waris K, Harjola VP, Marono D, Parenica J,
Kreutzinger P, Nieminen T, Pavlusova M, Tarvasmaki T, Twerenbold R,
Tolonen J, Miklik R, Nieminen MS, Spinar J, Mueller C, Johan Lassus J.
Ventricular conduction abnormalities as predictors of long-term survival
in acute de novo and decompensated chronic heart failure. ESC Heart
Failure 2016 Mar;3(1):35-43. Impact Factor 1.14
112. Twerenbold R, Jaeger C, Rubini GimŽnez M, Wildi K, Reichlin T, Nest-
elberger T, Boeddinghaus J, Grimm K, Puelacher C, Moehring B, Pretre G,
Schaerli N, Campodarve I, Rentsch K, Steuer S, Osswald S, Mueller C. Im-
pact of high-sensitivity cardiac troponin on use of coronary angiography,
cardiac stress testing and time to discharge in suspected acute myocardi-
al infarction. Eur Heart J 2016; Epub ahead of print. Impact Factor 15.064
113. Vafaie M, Slagman A, Möckel M, Hamm C, Huber K, MŸller C, Vollert
JO, Blankenberg S, Katus HA, Liebetrau C, Giannitsis E, Searle J. Prog-
nostic value of undetectable hs troponin T in suspected acute coronary
syndrome. Am J Med. 2016 Mar;129(3):274-82.e2. Impact Factor 5.61
114. Vanderberk B, Garweg C, Voros G, Flore V, Marynissen T, Sticher-
ling C, Zabel M, Ector J, Willems R. Changes in implantation patterns
and therapy rates of implantable cardioverter-defibrillators over time in
ischemic and dilated cardiomyopathy patients. Pacing Clin Electrophysi-
ol 2016;39:848-57. Impact Factor 1.44
115. Vanniyasingam T, Rodseth RN, Lurati Buse GA, Bolliger D, Burkhart
CS, Cuthbertson BH, Gibson SC, Mahla E, Leibowitz DW, Biccard BM,
Thabane L. Predicting the occurrence of major adverse cardiac events
within 30 days of a vascular surgery: an empirical comparison of the
minimum p value method and ROC curve approach using individual pa-
tient data meta-analysis. Springerplus. 2016 Mar 9;5:304. doi: 10.1186/
s40064-016-1936-8. Impact Factor 0.982
47
 10 Publikationen
Publikationen
116. Vassalli G, Klersy C, De Servi S, Galatius S, Erne P, Eberli F, Rickli H,
Hornig B, Bertel O, Bonetti P, Moccetti T, Kaiser C, Pfisterer M, Pedrazzini
G; BASKET-PROVE Investigators. Can the optimal type of stent be predic-
ted based on clinical risk factors? A subgroup analysis of the randomized
BASKET-PROVE trial. Am Heart J. 2016;173:1-7. Impact Factor 4.332
117. Volosyuk VK, Zhyla SS, Kravchenko VF, Morozov AV, Pustovoit VI,
Huniker P. Method of holographic imaging of inhomogeneities in the
density of a substance of a semitransparent medium using plane-parallel
laser radiation. Doklady Physics. Impact Factor 0.513
118. von Gunten S, Schaer BA, Yap SC, Szili-Torok T, KŸhne M, Sticher-
ling C, Osswald S, Theuns DA. Longevity of implantable cardioverter de-
fibrillators: a comparison among manufacturers and over time. Europace
2016;18:710-7. Impact Factor 4.021
119. von Rotz M, Aeschbacher S, Bossard M, Schoen T, Blum S, Schnei-
der S, Estis J, Todd J, Risch M, Risch L, Conen D. Risk factors for prema-
ture ventricular contractions in young and healthy adults. Heart. 2016.
Epub ahead of print. Impact Factor 5.693
120. Wagener M.; AbŠcherli R.; Honegger U.; SchŠrli N.; Prtre G., Twe-
renbold R., Puelacher C., Sunier G., Reddiess P., Rubini Gimenez M., Wil-
di K., Boeddinghaus J., Nestelberger T., Badertscher P., Sabti Z., Schmid
R., Leber R., Flores Widmer D., Shrestha S., Strebel I., Wild D., Osswald
S., Zellweger M., Mueller C., Reichlin T. Diagnostic and prognostic value
of lead aVR during exercise testing. Am J Cardiol 2016; in press. Impact
Factor 3.276
121. Wienbergen H*, Pfister O*, Hochadel M, Michel S, Bruder O, Remp-
pis BA, Maeder MT, Strasser R, von Scheidt W, Pauschinger M, Senges
J, Hambrecht R; Usefulness of Iron Deficiency Correction in Manage-
ment of Patients With Heart Failure [from the Registry Analysis of Iron
Deficiency-Heart Failure (RAID-HF) Registry]. RAID-HF (Registry Analy-
sis of Iron Deficiency–Heart Failure) REGISTRY Study Group.*equal con-
tribution. Am J Cardiol. 2016 Dec 15;118(12):1875-1880. doi: 10.1016/j.
amjcard.2016.08.081. Impact Factor 3.154
122. Wildi K, Twerenbold R, Jaeger C, Rubini GimŽnez M, Reichlin T, Stoll
M, Hillinger P, Puelacher C, Boeddinghaus J, Nestelberger T, Grimm K,
Grob M, Rentsch K, Arnold C, Mueller C. Clinical impact of the 2010-2012
low-end shift of high-sensitivity cardiac troponin T. Eur Heart J Acute Car-
diovasc Care. 2016 Apr 7. pii: 2048872616642952. [Epub ahead of print]
48
123. Wildi K., Nelles B., Twerenbold R., Maria Rubini GimŽnez, Tobias
Reichlin, HŽlne Singeisen, Sophie Druey, Philip Haaf, Zaid Sabti, Hillinger
P. , Jaeger C., Campodarve I., Kreutzinger P., Puelacher C., Moreno Weid-
mann Z., Gugala M., Pretre G., Doerflinger S., Wagener M., Stallone F.,
Freese M., Stelzig C., Rentsch K., Bassetti S, Bingisser R., Osswald S., Mu-
eller C. Safety and Efficacy of the 0h/3h-protocol for rapid rule-out of Myo-
cardial Infarction. Am Heart J. 2016; Nov;181:16-25. Impact Factor 4.463
124. Woehrle D, Martinez M, Bolliger D. Hereditary heterozygous factor
VII deficiency in patients undergoing surgery : Clinical relevance. Anaes-
thesist. 2016 Oct;65(10):746-754. Impact Factor 0.964
125. Wolfrum M, Fahrni G, de Maria GL, Knapp G, Curzen N, Kharbanda
RK, Fršhlich GM, Banning AP. Impact of impaired fractional flow reser-
ve after coronary interventions on outcomes: a systematic review and
meta-analysis. BMC Cardiovasc Disord. 2016 Sep 8;16(1):177. Impact
Factor 2.021
126. Zbinden R, Piccolo R, Heg D, Roffi M, Kurz DJ, Muller O, Vuilliome-
net A, Cook S, Weilenmann D, Kaiser C, Jamshidi P, Franzone A, Eberli
F, JŸni P, Windecker S, Pilgrim T. Ultrathin Strut Biodegradable Polymer
Sirolimus-Eluting Stent Versus Durable-Polymer Everolimus-Eluting
Stent for Percutaneous Coronary Revascularization: 2-Year Results of the
BIOSCIENCE Trial. J Am Heart Assoc. 2016 Mar 15;4(3):e003255. doi:
10.1161/JAHA.116.003255. Impact Factor 4.306
127. Zbinden R, von Felten S, Wein B, Tueller D, Kurz DJ, Reho I, Galatius
S, Alber H, Conen D, Pfisterer M, Kaiser C, Eberli FR. Impact of stent
diameter and length on in-stent restenosis after DES vs BMS implantati-
on in patients needing large coronary stents - a clinical and health-eco-
nomic evaluation. Cardiovasc Ther. 2016 Sep 23 [Epub ahead of print].
Impact Factor 2.243
 Reviews & Editorials
1. 2016 ESC Guidelines for the diagnosis and treatment of acute and
chronic heart failure: The Task Force for the diagnosis and treatment of
acute and chronic heart failure of the European Society of Cardiology
(ESC). Developed with the special contribution of the Heart Failure As-
sociation (HFA) of the ESC. Authors/Task Force Members; Document
Reviewers. Eur J Heart Fail. 2016 May 20. doi: 10.1002/ejhf.592. [Epub
ahead of print]. Impact Factor 5.135
2. 2016 ESC Guidelines for the diagnosis and treatment of acute and
chronic heart failure: The Task Force for the diagnosis and treatment of
acute and chronic heart failure of the European Society of Cardiology
(ESC) Developed with the special contribution of the Heart Failure As-
sociation (HFA) of the ESC. Ponikowski P, Voors AA, Anker SD, Bueno
H, Cleland JG, Coats AJ, Falk V, González-Juanatey JR, Harjola VP, Jan-
kowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B,
Riley JP, Rosano GM, Ruilope LM, Ruschitzka F, Rutten FH, van der Meer
P; Authors/Task Force Members; Document Reviewers. Eur Heart J.
2016 May 20. pii: ehw128. [Epub ahead of print]. Impact Factor 15.064
3. Attenhofer Jost Ch., Tobler D, Greutmann M. Pulmonalatresie. Herz-
blatt Ausgabe 04/2016.
4. Bolliger D, Tanaka KA. Fibrinogen-is it a universal haemostatic agent?
Br J Anaesth. 2016 Nov;117(5):548-550. No abstract available. Impact
Factor 5.616
5. Bolliger D, Zenklusen U, Tanaka KA. Point-of-care coagulation ma-
nagement algorithms during ECMO support: are we there yet? Minerva
Anestesiol. 2016 Mar 30. [Epub ahead of print]. Impact Factor 2.036
6. Donner B, HŠffner N, Dechant M, Thomet C, Pfammatter JP, Tobler D.
Transition Jugendlicher mit einer angeborenen Herzerkrankung. Cardio-
Vasc 2016, Vol. 15, Nr. 5.
7. Gonalves D, Hunziker P. Transmission-blocking strategies: the road-
map from laboratory bench to the community. Malaria journal 15 (1), 95.
Impact Factor 3.03
8. Greutmann M, Tobler D.Health insurance problems for adults with
congenital heart disease. Eur Heart J. 2016 vol 37(18). Impact Factor
15.064
9. Haaf P, Garg P, Messroghli DR, Broadbent DA, Greenwood JP, Plein
S. Cardiac T1 Mapping and Extracellular Volume (ECV) in clinical practi-
ce: a comprehensive review. J Cardiovasc Magn Reson. 2016 Nov
30;18(1):89. Review. PMID:27899132. Impact Factor 5.752
10. Harjola VP, Mebazaa A, CelutkienŽ J, Bettex D, Chioncel O, Falk V, Fi-
lippatos GS, Gibbs S, Leite-Moreira A, Lassus J, Masip J, Mueller C, Mul-
lens W, Naeje R, Nordegraaf AV, Parissis J, Riley J, Ristic A, Rosano G,
Rudiger A, Ruschitzka F, Seferovic P, Sztrymf B, Vieillard-Baron A, Yilmaz
M, Konstantinides S. Contemporary Management of Acute Right Ven-
tricular Failure: A Statement from the Heart Failure Association and the
Working Group on Pulmonary Circulation and Right Ventricular Function
of the European Society of Cardiology European Journal of Heart Failure.
Eur J Heart Fail. 2016;18:226-41. Impact Factor 5.135
11. Hollander JE, Than M, Mueller C. State-of-the-Art Evaluation of Emer-
gency Department Patients Presenting With Potential Acute Coronary
Syndromes. Circulation. 2016 Aug 16;134(7):547-64. Impact factor 17.047
12. Hunziker P. Nanomedicine translation from enabling technologies to
the patient: focus on infectious diseases. European Journal of Nanome-
dicine Impact Factor 0.64
13. Kuster GM, Liao R. Fortune favors the prepared: Safety and efficacy
of allogeneic hypoxia preconditioned mesenchymal stromal cells in pri-
mates. Circ Res 2016;118:908-910. Impact Factor 11.6
14. Liu K, Jiang X, Hunziker P. Carbohydrate-based amphiphilic nano
delivery systems for cancer therapy. Nanoscale 16091-16156. Impact
Factor 7.76
15. Maeder MT, Mueller C, Schoch OD, Ammann P, Rickli H. Biomarkers
of Cardiovascular Stress in Obstructive Sleep Apnea. Clin Chim Acta.
2016 Jul 2;460:152-163. doi: 10.1016/j.cca.2016.06.046. [Epub ahead of
print] Review. Impact Factor 2.799
16. Mair J, Lindahl B, Giannitsis E, Huber K, Thygesen K, Plebani M,
Mšckel M, MŸller C, Jaffe AS; Biomarker Study Group of the European
Society of Cardiology Acute Cardiovascular Care Association. Will sacu-
bitril-valsartan diminish the clinical utility of B-type natriuretic peptide
testing in acute cardiac care? Eur Heart J Acute Cardiovasc Care. 2016
Jan 12. pii: 2048872615626355. [Epub ahead of print]
17. Mart’n-S‡nchez FJ, Christ M, Mir— ñ, Peacock WF, McMurray JJ,
Bueno H, Maisel AS, Cullen L, Cowie MR, Di Somma S, Platz E, Masip
J, Zeymer U, Vrints C, Price S, Mueller C. Practical approach on frail
older patients attended for acute heart failure. Int J Cardiol. 2016 Nov
1;222:62-71. Impact factor 4.638
18. Mebazaa A, Tolppanen H, Mueller C, Lassus J, DiSomma S, Bak-
syte G, Cecconi M, Choi DJ, Cohen Solal A, Christ M, Masip J, Arrigo
M, Nouira S, Ojji D, Peacock F, Richards M, Sato N, Sliwa K, Spinar
J, Thiele H, Yilmaz MB, Januzzi J. Acute heart failure and cardiogenic
shock: a multidisciplinary practical guidance. Intensive Care Med. 2016
Feb;42(2):147-63. Impact Factor 7.422
19. Miro O, Peacock FW, Christ M, Cowie M, Cullen L, Maisel AS, Ma-
sip J, Miro O, McMurray J, Peacock FW, Price S, DiSomma S, Bueno
H, Zeymer U, Mebazaa A, Mueller C. European Society of Cardiolo-
gy - Acute Cardiovascular Care Association position paper on safe di-
scharge of acute heart failure patients from the emergency department.
European Heart Journal: Acute Cardiovascular Care 2016; Feb 21. pii:
2048872616633853. [Epub ahead of print]. Impact Factor 15.064
49
 10 Publikationen
Publikationen
20. Mont L, Pelliccia A, Sharma S, Biffi A, Borjesson M, Brugada Terra-
dellas J, CarrŽ F, Guasch E, Heidbuchel H, La Gerche A, Lampert R,
McKenna W, Papadakis M, Priori SG, Scanavacca M, Thompson P,
Sticherling C, Viskin S, Wilson M, Corrado D; Reviewers., Lip GY, Go-
renek B, Blomstršm Lundqvist C, Merkely B, Hindricks G, Hern‡ndez-
Madrid,Lane D, Boriani G, Narasimhan C, Marquez MF, Haines D,
Mackall J, Manuel Marques-Vidal P, Corra U, Halle M, Tiberi M, Niebauer
J, Piepoli M. Pre-participation cardiovascular evaluation for athletic parti-
cipants to prevent sudden cardiac death: Position paper from the EHRA
and the EAPCR, branches of the ESC. Endorsed by APHRS, HRS , and
SOLACE. Eur J Prev Cardiol 2017;24:41-69. Impact Factor 3.361
21. Mšckel M, Giannitsis E, Mueller C, Huber K, Jaffe AS, Mair J, Ple-
bani M, Thygesen K, Lindahl B; Biomarker Study Group of the European
Society of Cardiology Acute Cardiovascular Care Association. Rule-in of
acute myocardial infarction: Focus on troponin. Eur Heart J Acute Cardi-
ovasc Care. 2016 Jun 2. pii: 2048872616653228. [Epub ahead of print.
22. Mueller C, Giannitsis E, Mšckel M, Huber K, Mair J, Plebani M, Thy-
gesen K, Jaffe AS, Lindahl B; Biomarker Study Group of the ESC Acute
Cardiovascular Care Association. Rapid rule out of acute myocardial in-
farction: novel biomarker-based strategies.Eur Heart J Acute Cardiovasc
Care. 2016 Jul 1. pii: 2048872616653229. [Epub ahead of print]
23. Mueller C, Patrono C, Roffi M. Background, fundamental concepts,
and scientific evidence of the high-sensitivity cardiac troponin 0h/1h-
algorithm for early rule-out or rule-in of acute myocardial infarction. Eur
Heart J. 2016; Epub ahead of print. Impact Factor 15.064
24. Murray K and Burkard T. [Hyperuricemia, gout and cardiovascular
diseases]. Ther Umsch. 2016;73:141-6.
25. Ramakrishna H, Gutsche JT, Patel PA, Evans AS, Weiner M, Morozo-
wich ST, Gordon EK, Riha H, Bracker J, Ghadimi K, Murphy S, Spitz W,
MacKay E, Cios TJ, Malhotra AK, Baron E, Shaefi S, Fassl J, Weiss SJ,
Silvay G, Augoustides JG. The Year in Cardiothoracic and Vascular Anes-
thesia: Selected Highlights from 2016. J Cardiothorac Vasc Anesth. 2016
Oct 14. pii: S1053-0770(16)30498-0. doi: 10.1053/j.jvca.2016.10.009.
[Epub ahead of print] Review. Impact Factor 1.519
26. Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F,
Bax JJ, Borger MA, Brotons C, Chew DP, Gencer B, Hasenfuss G, Kjeld-
sen K, Lancellotti P, Landmesser U, Mehilli J, Mukherjee D, Storey RF,
Windecker S. 2015 ESC Guidelines for the management of acute coro-
nary syndromes in patients presenting without persistent ST-segment
elevation. Task Force for the Management of Acute Coronary Syndro-
mes in Patients Presenting without Persistent ST-Segment Elevation of
the European Society of Cardiology (ESC)]. G Ital Cardiol (Rome). 2016
Oct;17(10):831-872. doi: 10.1714/2464.25804.
50
27. Rutz T, Wustmann K, Prsa M, VallŽe JP, Donner B, Bremerich J, De-
luigi C, Zellweger M, Tobler D, Kellenberger C, Wahl A, Monney P, Buser
P, Gudinchet F, Schwitter J, Valsangiacomo BŸchel E. Cardiac magenetic
resonance imaging in congenital heart disease. Cardiovascular Medici-
ne. 2016;19(06):176-184.
28. Salieb-Beugelaar GB, Zhang B, Nigo MM, Frischmann S, Hunziker
P. Improving diagnosis of pneumococcal disease by multiparameter tes-
ting and micro/nanotechnologies. European Journal of Nanomedicine 8
(3), 115-128. Impact Factor 0.64
29. Shulga D, Morozov O, Hunziker P. A Tensor B-Spline Approach for
Solving the Diffusion PDE With Application to Optical Diffusion Tomo-
graphy. IEEE Transactions on Medical Imaging 2016.
30. Tobler D, Peterli Wolf B. herznetz.ch - Verbesserung der Wahrneh-
mung und Verbreitung von Informationen. Herzblatt Ausgabe 04/2016.
31. Vargas KG, Kassem M, Mueller C, Wojta J, Huber K. Copeptin for the
Early Rule-out of Non-ST-elevation Myocardial Infarction. Int J Cardiol
2016; Nov 15;223:797-804. Impact factor 4.638
32. Visone R, Gilardi M, Marsano A, Rasponi M, Bersini S, Moretti M.
Cardiac Meets Skeletal: What‘s New in Microfluidic Models for Musc-
le Tissue Engineering. Molecules. 2016 Aug 26;21(9). pii: E1128. doi:
10.3390/molecules21091128. Review. Impact Factor 4.465
33. Xu, L., and Brink, M. (2016) mTOR, cardiomyocytes and inflamma-
tion in cardiac hypertrophy. Biochim Biophys Acta Impact Factor 5.34
34. Zhang B, Hunziker P. Cost-effectiveness: A challenge for dengue ra-
pid nanodiagnostic tests. Nanomedicine 2016 Jan; 12(19):251-2. Impact
Factor Impact Factor 4.889
 Letters to the editor
1. Badertscher P, du Fay de Lavallaz J, Mueller C. Prevalence of pulmo-
nary embolism among patients hospitalized for syncope. N Engl J Med
2016;in press. Impact factor 59.558
2. Boeddinghaus J, Twerenbold R, Nestelberger T, Wildi K, Mueller C.
Measurement of high-sensitivity cardiac troponin for exclusion of myo-
cardial infarction. Lancet 2016; Vol 387 June 4, 2016, 2288. Impact fac-
tor 44.002
3. Kohzuharov N, Sabti Z, Mueller C. Nitrates in the treatment of heart fai-
lure with preserved ejection fraction. N ENgl J Med 2016;374(16):1588-
9. Impact Factor 59.558
4. Mueller C, Giannitsis E, Lindahl B. TRAPID-AMI In reply. Ann Emerg
Med. 2016 Jun;67(6):794-5. doi: 10.1016/j.annemergmed.2016.02.037.
5. Zellweger MJ. The complex principle of cause and effect. J Nucl Car-
diol. 2016 May 4. [Epub ahead of print] No abstract available. PMID:
27146886
 Case reports
1. Celikyurt U, Sticherling C, Reichlin T, Schaer B, Osswald S, KŸhne M.
Wolff-Parkinson-White syndrome and diverticulosis of the heart? Cardio-
vasc Med 2016;19:34-36. Impact Factor 1.658
2. D‘Antico C, Hofer A, Fassl J, Tobler D, Zumofen D, Goettel N. Case
Report: Emergency awake craniotomy for cerebral abscess in a patient
with unrepaired cyanotic congenital heart disease F1000Research 2016;
5:2521. F1000Res. 2016 Oct 14;5:2521
3. D‘Antico C, Hofer A, Fassl J, Tobler D, Zumofen D, Goettel N. Emer-
gency awake craniotomy for cerebral abscess in a patient with unre-
paired cyanotic congenital heart disease.
4. Dayal N, Burri H, Sticherling C, Auricchio A. The subcutaneous im-
plantable cardioverter-defibrillator: pros and cons. Cardiovasc Med
2016;19:121-127. Impact Factor 1.658
5. Heid J, Vogel B, Kristen A, Kloos W, Kohler B, Katus HA, Korosoglou
G. Interventional treatment of the left subclavian in 2 patients with coro-
nary steal syndrome. World J Cardiol 2016; In press
6. Knecht S, Novak J, Kühne M. Entrapment of a diagnostic catheter in
a novel multipolar basket catheter (Orion) during right atrial mapping.
Europace 2016; 18:1186. Impact Factor 4.021
7. Knecht S, Spies F, Altmann D, Reichlin T, Sticherling C, KŸhne M.
Electroanatomic Mapping of Atrial Tachycardia-Manual vs. Automated
Annotation. Man versus Machine. Heart Rhythm Case Report accepted
8. Kopp S, Kiencke S, Sticherling C, Reichlin T. Recurrent symptomatic re-
gular tachycardia. Cardiovasc Med 2016;19:185-187. Impact Factor 1.658
9. Kuenzli E1, Labhardt N2, Balestra G3, Weisser M4, Zellweger MJ5,
Blum J2. Staphylococcus aureus Endocarditis as a Complication of
Toxocariasis-Associated Endomyocarditis With Fibrosis: A Case Report.
10. Mauermann E, Vškt C, Tsakiris DA, Tobler D, Girard T. Heparin-in-
duced thrombocytopenia in pregnancy: an interdisciplinary challenge-a
case report and literature review. Int J Obstet Anesth. 2016 May;26:79-
82. Impact Factor 2.04
11. Reichlin T, AbŠcherli R, Twerenbold R, Kühne M, Schaer B, Mueller C,
Sticherling C, Osswald S. Advanced ECG in 2016 and beyond: is there
more than just a tracing? Swiss Med Wkly 2016; 146:w14303. Impact
Factor 1.459
12. Reichlin T, KŸhne M, Sticherling C. Repetitive inappropriate implan-
table cardioverter-defibrillator shocks due to insulation failure with ex-
ternalized conductor cables of a Biotronik Linox SD ICD lead. Europace.
2016 May;18(5):686. Impact Factor 4.021
13. Schšn, KŸhne M. Vorhofflimmern. Ther Umsch. 2016;73(6):333-9.
14. Sticherling C, KŸhne M. Pulmonary vein isolation without assessing
pulmonary vein potentials - not there yet. Heart Rhythm 2016 (epub).
Impact Factor 4.391
15. Sticherling C. Methadon und QTc-VerlŠngerung - eine versteckte Ge-
fahr. Swiss Medical Forum 2016;16:157
16. Sticherling C. Pulmonary vein isolation: Is our target the one we
think? Heart Rhythm 2016; 13:1358-9. Impact Factor 4.391
17. v. Gunten S, Crevoisier JL, KŸhne M, Reichlin T, Osswald S, Sticher-
ling C, Schaer B. To explant, or not to explant, that is the question. Car-
diovasc Med 2016; 19:237-238. Impact Factor 1.658
 Books / Book chapters
1. Herzog B, Plein S, Greenwood J, Co-authors: Garg P, Haaf P. ESC CMR
pocket guide - Endorsed by the working group on CMR of the European
Society of Cardiology (ESC). www.cmr-guide.com, (Version 3.0 2016)
2. Kuster GM, Della Verde G, Liao R, Pfister O. Cell Therapy for Cardiac
Regeneration. In: J. Laurence, M. Van Beusekom, P. Baptista, A. Atala,
eds. Translating Regenerative Medicine to Clinics. United States of Ame-
rica: Academic Press, Elsevier Inc., 2016; pp. 266-283.
3. Vischer AS and Burkard T. Principles of Blood Pressure Measurement
- Current Techniques, Office vs Ambulatory Blood Pressure Measure-
ment. Adv Exp Med Biol. 2016.
51
 11 Auszeichnungen

Auszeichnungen
 Habilitationen
Beat SchŠr: Titularprofessur
 Dissertationen
Dissertationen bei Prof. Christian MŸller
Dr. Bourtzou Anna: Diagnostic and prognostic value of ST - seg-
ment deviation scores in suspected acute myocardial infarction
Dr. Cesal Martina: Direct comparison of B-type natriuretic pepti-
de and midregional pro-atrial natriuretic peptide in the diagnosis
of acute heart failure
Dr. Druey Sophie: Early rule-out and rule-in of myocardial infarc-
tion using sensitive cardiac Troponin I
Dr. Kern Anklin Vera: 2h-algorithm for triage towards "rule-out“"
and "rule-in" of acute myocardial infarction using high-sensitivi-
ty cardiac troponin I
Dr. Lee Gino: Clinical benefit of high-sensitivity cardiac Troponin
I in the detection of exercise-induced myocardial ischemia
Dr. Marono David: VentrikulŠre Reizleitungsstšrungen als PrŠ-
diktoren von LangzeitŸberleben in akuter Herzinsuffizienz
Dr. Merki Ramona Olivia: Incremental value of Copeptin for Ra-
pid Rule Out of Acute Myocardial Infarction
Dr. Nestelberger Thomas: Characterization of the observe zone
of the ESC 2015 high-sensitivity cardiac troponin 0 h/1 h-algo-
rithm for the early diagnosis of acute myocardial infarction
Dr. Neuhaus Jean-Daniel: A diurnal rhythm of cardiac troponin:
consequences for the diagnosis of acute myocardial infarction
Dissertationen bei Prof. David Conen
Dr. Kofler Thomas: The interrelationships of birthweight, inflam-
mation and body composition in healthy adults
Dr. Leib Stefanie: Relationships of iron metabolism with insulin
resistance and glucose levels in young and healthy adults
Dr. Ruperti Repilado Javier: Relationship of N-Terminal fragment
of Pro-B-Type Natriuretic Peptide and copeptin with erythrocy-
tes-related parameters: A population-based study
Dr. Tabord Alexandra: Die neuen oralen Antikoagulantien zur
SchlaganfallprŠvention bei Patienten mit Vorhofflimmern in der
Schweiz - Eine Bestandsaufnahme
Dr. Metin Fatih: "Relationships of electrocardiographic parame-
ters with ambulatory hypertension in young and healthy adults"
 Forschungspreise
Dr. Raphael Twerenbold: "Otto Hess Research Award"
der Schweizerischen Gesellschaft fŸr Kardiologie
Dr. Jasper Boeddinghaus: "Otto Hess Research Award"
der Schweizerischen Gesellschaft fŸr Kardiologie
Dr. Jasper Boeddinghaus: GREAT Meeting, Presentation Award
Dr. Patrick Badertscher: GREAT Meeting, Presentation Award
Dr. Krisai Philipp; Dr. Stefanie Aeschbacher: Pfizer Forschungs-
preis 2016

Dr. Eisenhut Timo: Complement Factors in Acute Heart Failure: Dr. Sou Seoung Mann: Direct comparison of cardiac Troponin Dr. Aeschbacher Stefanie, PhD: "Lifestyle and heart rate variabi-
Potential Role in Pathophysiologiy, Response to Treatment and I and cardiac Troponin T in the detection of exercise-induced lity in the general population"
Impact on long-term Survival myocardial ischemia

Dr. Engels Ulrike: Optimizing early rule-out strategies for NSTE-
MI: utility of a second measurement of high-sensitivity cardiac
troponin T or Copeptin at one hour
Dr. Fischer Catherine Marie-Madeleine: Risk-stratification in pa-
tients with acute chest pain using three high-sensitivity cardiac
troponin assays
Dr. Fischer Clarissa Felicitas: Cardiomyocyte injury induced by
hemodynamic cardiac stress: differential release of cardiac bio-
markers
Dr. Stoll Melanie Patricia: Clinical impact of the 2010-2012 low-
end shift of high-sensitivity cardiac troponin T
Dr. Walukiewicz Astrid Nicole: Optimal Cut-off Levels of More
Sensitive Cardiac Troponin Assays for the Early Diagnosis of
Myocardial Infarction in Patients with Renal Dysfunction
Dr. ZŸrcher Stephan Michael: Delayed release of brain natriure-
tic peptide to identify myocardial ischemia

Dr. Heitzelmann Karl-Frieder: Clinical Impact of Sex-specific Cutt-

off Values of High-sensitivity Cardiac Troponin T in Suspected
Myocardial Infarction

52 53
 12 Kontakt

Kontakt
 Kardiologie Basel  Herzchirurgie Basel

Chefarzt Chefarzt
Prof. Dr. med. Stefan Osswald Prof. Dr. med. Friedrich Eckstein

Anschrift Anschrift
Kardiologie Basel Herzchirurgie Basel
UniversitŠtsspital Basel UniversitŠtsspital Basel
Petersgraben 4 Spitalstrasse 21
CH - 4031 Basel CH - 4031 Basel
unispital-basel.ch/kardiologie unispital-basel.ch/herzchirurgie

Allgemeine AuskŸnfte Chefarztsekretariat

Tel +41 61 265 44 44, Fax +41 61 265 45 98
Email: kardiologie@usb.ch
Anmeldung ambulante und stationŠre Patienten
Tel. +41 61 265 44 45, Fax +41 61 265 55 75
Email: anmeldung.kardiologie@usb.ch
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Tel. +41 61 328 65 27, Fax +41 61 265 55 03
Email: karamba@usb.ch
Dienstarzt Kardiologie
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Email: jolanda.giess@usb.ch
Anmeldung
StationŠre Patienten Tel. + 41 61 265 71 45
Ambulante Patienten Tel. + 41 61 265 71 45
Aortensprechstunde Tel. + 41 61 265 71 46
Dienstarzt Herzchirurgie
Tel. + 41 61 556 58 58

Impressum

Herausgeber: Herzzentrum Basel; Redaktion: Christoph Kaiser (Leitung), Stefan Osswald, Friedrich Eckstein, Christian MŸller, Florian
RŸter, Markus Riesterer, Arton Jusaj, Ursula Vogt
Fotos: Markus Riesterer, Fabian Fiechter, Foto & Print Center USB, Christian Jaeggi, Patrick Sayer (Foto S. 55)
Konzeption: Markus Riesterer; Gestaltung: strawberry design; Druck: strawberry events; Auflage: 2'000 Ex.
Diese Publikation, einschliesslich all ihrer Texte, ist urheberrechtlich geschŸtzt. Jede Verwendung ausserhalb der engen Grenzen des
Urheberrechts ist ohne Zustimmung des Herzzentrums und der beteiligten Institutionen unzulŠssig und strafbar. Dies gilt insbesondere
fŸr VervielfŠltigungen, †bersetzungen, Mikroverfilmungen, sowie fŸr die Einspeicherung und Verarbeitung in elektronischen Systemen.
54 55
unispital-basel.ch/kardiologie I unispital-basel.ch/herzchirurgie