GENERIC DOSE, INDICATION/ ADVERSE/SIDE NURSING RATIONALE CLIENT

NAME AND STRENGTH & MECHANISM OF EFFECTS RESPONSIBILITIES (10%) TEACHING

BRAND NAME FORMULATION DRUG ACTION DRUG INTERACTION (15%) (20%)
(15%) (15%)
(10%) (10%)

GENERIC: ORDERED: INDICATIONS: ADVERSE ASSESSMENT:

Gentamicin Serious infection REACTION: 1. Assess patient’s
sulfate caused by CNS: headache, infection and
TIMING: sensitive strains lethargy, numbness, hearing before
of Pseudomonas paresthesia, peripheral starting therapy and
aeruginosa, neuropathy, regularly thereafter.
BRAND: Escherichia coli, neurotoxicity, seizures, 2. Obtain specimen
DURATION: Proteus, twitching for culture and
Klebsiella, EENT: ototoxicity sensitivity tests
unknown Serratia, GU: nephrotoxicity before giving the
Eneterobacter, Hematologic: first dose.
CLASSIFICA Citrobacter, agranulocytosis, 3. weigh patient
TION: Staphylococcus. leucopenia, and review baseline
OTHER FORMS: thrombocytopenia renal function
Aminoglycoside; Injection: 40 M.O.A.: Other: hypersensitivity studies before
antibiotic mg/ml (adults), Chemical effect: reactions therapy and
10 mg/ml Inhibits protein regularly during
(pediatrics), 2 synthesis by DRUG therapy
mg/ml binding to INTERACTIONS: 4. therapy usually
(intrathecal) ribosomes. Drug-drug: Acyclovir, continues for 7 to
IV Infusion amphotericin B, 10 days. If no
(premixed): 40 Therapeutic cisplatin, response occurs in
mg, 60 mg, 80 effect: Kills methoxyflurane, other 3 to 5 days, therapy
mg, 90 mg, 100 susceptible aminoglycosides, maybe stopped
mg, 120 mg, 160 bacteria (many vancomycin: May
mg, 180 mg aerobic gram- increase ototoxicity and
available in saline negative nephrotoxicity. Use
solution organisms and together cautiously.
some aerobic Diuretics: May increase
gram-positive ototoxicity. Avoid use
organisms). Drug together.
may act against General Anesthetics:
some May increase effects of
aminoglycoside- non-depolarizing
resistant bacteria. muscle relaxant,
including prolonged
respiratory depression.
Use together only when
necessary.
Neurotoxic drugs: May
increase neurotoxicity.
Avoid use together.
Parenteral ampicillins:
May inactivate
gentamicin in vitro.
Don’t mix together.