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Amelogenesis
The process by which the Internal Enamel Ep-
enamel is formed you will
read about the diffrent stag-
ithelium
es this process has you will Deposits and later modifies enamel and it
read about toms’ process and is responsible for the formation of enamel
many other sturctures and only when the tooth differentiate and be-
more in this issue. come Ameloblasts (enamel forming cells),
read this issue to find out more about the
other layers.
Life cycle of
Enamel A dental importance
it consists of 5 stages in this is- in this issue we will stumble upon a very
sue we disscuess the first one important example which is tooth etching
which is presecrotery stage read this issue to find more about it.
read this issue to know more
about it.
JD
Oralhistologysubject
MK
One
Page “a page that sums it all “
But what about the other layers? Actually they also play an important role in forming the Enam-
el (please refer to table 1 next page) note that these functions are not completely understood.
You should note that the Enamel dose not form all at once, the process starts at the cusp tips
then >> Incisal edges then finally >> around the cervical extension of the crown, this is why
at 30 days you will see active Internal enamel Epithelium cells that have been converted into
Ameoblasts started to form Enamel but at the same time other areas will still have Internal
Enamel Epithelium that have not yet been converted) “By the time enamel is completed each
ameloblast will have completed the same life cycle “, we have a life cycle for each enamel cell or
ameloblast when the enamel is formed their life cycle ends.
the tip of tomes’ processes will deposit the core of the prism of enamel and the sides of tomes
processes will deposit the periphery in other words the middle of prisms will form the tip of
toms’ and the periphery of these prisms will form the prongs , “TP infills the residual pits as
they retreat from the prism’s core” here the idea is given in two examples the first one in the
aspect of the Tomes’ processes and the second one in the aspect of Primes note that the two
are the same.
Once the full thickness of enamel matrix has been laid down (this is brought by as we said protein
synthesis and mineralization )
A final important note about secrotry stage, by the end of secretory stage the final result between
the two processes of Protein synthesis and Mineralization are not equal, in fact protein is more
than minerals content or the calcified enamel in the enamel matrix, later on in “maturation stage”
the protein to mineralization content will be more equal (more minerals content).
Transition stage :
“Initially deposited enamel is high in protein & water & low in minerals “ as we just said above ,
the doctor gave some numbers (protein = 70% and minerals are = 30% ) to quailze these numbers
(the protein and minerals ) “Maturation involves converting the initially deposited enamel into
the fully mineralized enamel” so here we remove the non calcified and we put a calcified enamel
Transition stage is the stage where the ameloblasts change from a secretory to maturation forms
Ameloblasts become reduced in height & number and Protein synthesis organelles are reduced
this is because there is no more production of protein so there is no need for these organelles to
be present
Blood vessels invaginate enamel organ and reach the proximal end of ameloblasts
the end