Understand more about...

· Incidence risk

DID YOU KNOW

of Down syn-
drome increas- Mongoliod!!!
THAT… es with mother's
age D o w n
… “Down Syn-
drome” was named after
John Langdon Down, an
· Less than 1-in-
They might be different but they are hu-
mans. And a little consideration please…
Syndrome
1,000 risk of
Englishman who first Down syndrome
characterized the syn- for women un- The Down's Syndrome Association has re-
drome as a state of mental der 30 sponded to today's media reports that a boy
disability. with Down's syndrome was charged by the
Down syndrome was the police following an alleged attack on an Asian
· About 1-in-25 student.
first human syndrome
risk of Down
attributed to a chromoso-
syndrome for a Carol Boys, Chief Executive of the Down's
mal disorder
45-year-old Syndrome Association, said:
mother "At the Down's Syndrome Association we
strive to overturn myths about people with
Down's syndrome - one of which is that they
are universally ‘sweet' and ‘cuddly'. People
A Mother Carrying her with Down's syndrome are no different to the
rest of human society in that they are quite
Child capable of exhibiting a whole range of human
emotions and prejudices. It is possible that
There are several ways to discover that a mom someone with Down's syndrome could have
racist views but it is also possible that they
may be carrying a child affected with DS. Usu-
could be influenced by views of friends, family
ally these are through genetic testing such and society.
as amniocentesis, chorionic villus sam-
pling (CVS), or percutaneous umbilical cord Read the article:
blood sampling (PUBS). http://www.downs-syndrome.org.uk/news-and-
media/press-releases/2008/144-police-charged-boy-
With the discovery with-downs-syndrome-a-response-from-the-downs-
of karyotype techniques syndrome-association.html
since 1950s, it became
possible to identify ab-
normalities of chromo-
somal number or shape
such as DS..
References:
Liptak, Gregory S (December 2008). "Down Syndrome
(Trisomy 21; Trisomy G)". Merck Manual. Retrieved 2010-12-
04. "Symptoms"

www.cafamily.org.uk/medicalinformation/.../d30_3.html

It is really arranged in this pamphlet
that the first phrase that you would read is
“understand more”. Why did I not use “learn
more about”? Well, not only is the objective
of this piece of paper is to inform but also to
gain sympathy for genetically disordered
people. Stop. Look. Read.
What is Down Syndrome?
Down syndrome (DS) is a disorder in the
genes which is caused by having an extra
21st chromosome. This form of Down syn-
drome is called Trisomy 21. The extra chro-
mosome causes problems with the way the
body and brain develop. About 4% of those
with Down syndrome have been found to
have a translocation of chromosome 21, usu-
ally associated with chromosome 14, 15, or
22.
It is sporadic therefore its inheritance pattern
is not certain or unpredictable.
How Do I Know If A Person
has DS? Ed u c a t i o n s t i l l r e m a i n s t h e
most effective management
It is not possible however to know the symp-
for DS patients. Since almost
toms that a affected child will develop.
all of them have cognitive dif-
Some may show of some or all of these symp- ficulty, it is much prescribed
toms: to give them your most pa-
 microgenia (abnormally small chin) tient and kindest attention.
 oblique eye fissures with skin folds on the
inner corner of the eyes
 muscle hypotonia (poor muscle tone)
 a protruding tongue or macroglossia,
caused by the small oral cavity
 a short neck
 Brushfield spots, characterized by white
spots on the iris
 excessive joint laxity
 excessive space between large toe and se-
cond toe, a single flexion furrow of the fifth
finger
 usually 5’1” height for adult men and 4’9”
for adult women
Not only physical abnormalities are being man-
ifested but also in the intellectual aspect of the
affected person. Most individuals with Down
syndrome have intellectual disability in the
mild (IQ 50–70) to moderate (IQ 35–50) range,
with individuals having Mosaic Down syn-
drome typically 10–30 points higher.