Beruflich Dokumente
Kultur Dokumente
New Delhi
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Questions for CSIR NET JRF (Paper—II)
1. Compare & contrast: a sodium atom & a sodium ion; a double bond & a
triple bond ; an atom of weak & strong electro negativity ; the electron
2. Why do polar molecules dissolve so readily in water? Why don’t fat droplets
dissolve in water? What is the concept behind formation of fat droplets in water?
properties of carbon atom are critical to life? Which compound makes the bulk
of a living organism?
4. If you were to add Hcl to water, what effect would this have on the hydrogen ion
concentration? On the pH? On the ionic charge of any protein in solution? What is
5. What is meant by protein domains & motifs ? How protein folding takes
place? Where protein folding takes place? Why some proteins are found as
quaternary structure?
6. How are the properties of an alpha helix different from a beta strand? How are
they similar? How do each of these secondary structure affect the properties of
7. Name two nonpolar amno acids. Sickle cell anaemia results from a substitution of
North Campus: 2274, Hudson Line, Behind Khalsa College (DU), Kingsway Camp, Delhi -110 009
South Campus: 28-A/11A, 1st Floor, Jia Sarai, Near IIT, Hauz Khas, New Delhi -110 016
Contact Number: 9350232207, 9891602060
a valine for a glutamate. What do you expect the effect might be if mutation were
Group—A Group—B
xi) Nucleus
xii) A protein
9. Which of the two photosystems operates at the most negative redox potential?
Which among them generates the strongest reducing agent? Which among them
10. Of the following substances PQH2, reduced cytochrome b6, reduced feredoxin,
NADP+, NADPH, O2, H2O, Tyrz+, Which is the strongest reducing agent? Which is
the strongest oxidising agent? Which has the strongest affinity for electrons? Which
11. In photosynthesis, the capture of light results in the release & subsequent
release & transfer of electrons. What is the reaction behind the process of
North Campus: 2274, Hudson Line, Behind Khalsa College (DU), Kingsway Camp, Delhi -110 009
South Campus: 28-A/11A, 1st Floor, Jia Sarai, Near IIT, Hauz Khas, New Delhi -110 016
Contact Number: 9350232207, 9891602060
photosynthesis? From what molecules are the electrons eventually derived? In
12. What is tight junction? How does the structure of tight junction contribute to
its function? What does freeze fracture analysis tell you about the structure of
13. Describe the components that make up a plant cell wall & the role of each in
the wall’s structure & function. Distinguish between cellulose & hemicellulose, a
cellulose molecule & a myofibril, a pprimary cell wall & a secondary cell wall.
14. In which part of a cell would you expect the following compounds to be first
15. Draw a schematic diagram of microtubule. What is myosin & kinesin? Some
members of kinesin family contain only a single heavy chain. How would you expect
their activity in an in vitro motility assay to differ from that of kinesin itself?
17. Compare the organisation of the genes that code for the large rRNA, 5S RNA,
& tRNA within the invertebrate genome. What is the relationship between hnRNA &
mRNA?
18. What are Barr bodies? Who gave the concept of Barr bodies? How many Barr
19. What is cDNA library? How it is different from a genomic DNA library? What
North Campus: 2274, Hudson Line, Behind Khalsa College (DU), Kingsway Camp, Delhi -110 009
South Campus: 28-A/11A, 1st Floor, Jia Sarai, Near IIT, Hauz Khas, New Delhi -110 016
Contact Number: 9350232207, 9891602060
20. Suppose that Messelson & stahl had carried out their experiment by growing
cells in medium with 14-N & then transferred the cells to medium containing
15-N. How would the bands within the centrifuge tubes have appeared if
weredispersive?
21. What is autoradiography? Describe how the use of 3-H thymidine &
autoradiography can be used to determine the length of the various periods of the
cell cycle.
22. What is the effect of fusing a cell in G1 with one in S; of fusing a G1 phase
23. Describe the events that occur in a cell during prometaphaase & during
anaphase. How do the events of mitotic prophase prepare the chromatids for
24. Constrast the overall roles of mitosis & meiosis in the lives of a plant or
animal. How do the nuclei formed by these two processes differ from one
another?
25. What is crossing over? Describe Holliday model of crossing over? Is this a
26. How was it demonstrated that genetic recombination took place by a breakage
& reunion mechanism? In which phase of cell cycle does this happen? What
are the other events that take place during this phase?
27. How the Ca2+ concentration of a cell is is maintained? What is the role of
North Campus: 2274, Hudson Line, Behind Khalsa College (DU), Kingsway Camp, Delhi -110 009
South Campus: 28-A/11A, 1st Floor, Jia Sarai, Near IIT, Hauz Khas, New Delhi -110 016
Contact Number: 9350232207, 9891602060
calcium binding protein in eliciting a response? Why the concentration of
28. Ca2+ , IP3, & cAMP have all been described as secondary messangers. In
what ways are their mechanism of action similar or different? Suggest some
29. Describe the two forms of diabetes & the causes of its occurrence. Suggest 3
molecular abnormalities that results in increase in sugar level in blood & urine
of an individual.
30. What do you understand by programmed cell death? Why certain cells have
longer half life than others? What all molecules are involved in this
event?
31. Which type of analytical techniques were used to conclude the structure of DNA?
Make a list of the various forms of DNA? Which form of DNA is mostly found in
membrane fraction?
34. what is active transport? Make a list of the active transport going inside a
North Campus: 2274, Hudson Line, Behind Khalsa College (DU), Kingsway Camp, Delhi -110 009
South Campus: 28-A/11A, 1st Floor, Jia Sarai, Near IIT, Hauz Khas, New Delhi -110 016
Contact Number: 9350232207, 9891602060
reaction? What we call the proteins that carry out active transport?
35. many different types of cells possess receptors that bind steroid hormones.
Where in the cell do you think these receptors might reside? Name a hormone
that regulates blood glucose level. Where in the cell the insulin receptor should
Plants. How do these differences affect the ability of these plants to grow in
37. Describe the basic plan of TCA cycle, indicating the reactions that require
energy input. Why it is called as a cycle? Why does energy has to be expended
38. What is the relationship between the energy content of a photon & wavelength
of light? How does the wavelength of light determine whether or not it will
39. What are cyclic & non cyclic photophosphorylation? Who discovered the
40. Why are catabolic pathways described as convergent and anabolic pathways as
anaerobically or aerobically.
North Campus: 2274, Hudson Line, Behind Khalsa College (DU), Kingsway Camp, Delhi -110 009
South Campus: 28-A/11A, 1st Floor, Jia Sarai, Near IIT, Hauz Khas, New Delhi -110 016
Contact Number: 9350232207, 9891602060