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PENDIDIKAN:

• S1 FAKULTAS KEDOKTERAN UNIVERSITAS INDONESIA, TAHUN 2003


• PENDIDIKAN DOKTER SPESIALIS ILMU KESEHATAN ANAK FKUI
RSCM, TAHUN 2011
PEKERJAAN:
• STAF DIVISI RESPIROLOGI ANAK RUMAH SAKIT ANAK BUNDA HARAPAN
KITA JAKARTA (RSABHK)

PELATIHAN:
• INTERNATIONAL CHILDHOOD TB TRAINING COURSE, DESMOND TUTU TB
CENTRE, UNIVERSITEIT STELLENBOSCH, SOUTH AFRICA, TAHUN 2018
• PAEDIATRIC FLEXIBLE BRONCHOSCOPY COURSE, NATIONAL UNIVERSITY
HOSPITAL, SINGAPORE, TAHUN 2016
ORGANISASI:
• ANGGOTA UNIT KELOMPOK KERJA RESPIROLOGI ANAK – IDAI
• ANGGOTA SATGAS SIAGA PENANGGULANGAN BENCANA PP IDAI
• ANGGOTA IDAI CABANG DKI JAKARTA
• ANGGOTA RESPIRATORY CARE INDONESIA (RESPINA)
• INSTRUKTUR EMERGENCY FIRST AID COURSE IMANI CARE
https://covid19.go.id/peta-sebaran
https://covid19.go.id/peta-sebaran
https://covid19.go.id/peta-sebaran
https://covid19.go.id/peta-sebaran
https://doi.org/10.1016/j.cell.2020.08.021
https://doi.org/10.1016/j.cell.2020.08.021
https://doi.org/10.1016/j.cell.2020.08.021
https://doi.org/10.1016/j.eclinm.2020.100433, A. Hoang et al. / EClinicalMedicine 24 (2020) 100433

https://doi.org/10.3389/fped.2021.668484
Arch Dis Child 2020;0:1-11. doi:10.1136/archdischild-2020-320338








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JAMA Pediatr. 2021;175(2):176-184. doi:10.1001/jamapediatrics.2020.5052





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https://doi.org/10.1016/j.ijid.2021.04.019
https://doi.org/10.1016/j.ijid.2021.04.019
PNAS October 6, 2020 117 (40) 24620-24626; https://doi.org/10.1073/pnas.2012358117


BioRender (2021). The SARS-CoV-2 Variants of Concern. Retrieved from https://app.biorender.com/biorender-templates/figures/5e99f5395fd61e0028682c01/t-609a99442a2d6e00a4d3fc38-the-sars-cov-2-variants-of-concern
Table by Eric Topol, MD
Table by Eric Topol, MD
BMJ 2020;370:m3223
<8 jam Aluminium
Stainless steel

24 jam Kertas
Baju

Besi
48 jam Plastik
Kertas

Kaca
Plastik

4 hari
PVC
Karet silicon
Keramik
Teflon
Metal
Coronavirus Disease 2019: Tinjauan Literatur Terkini. Jurnal Penyakit Dalam Indonesia. Vol. 7, No. 1. Maret 2020
Area terpapar Frekuensi
Sistem organ
(dewasa) paparan
Kulit 4 m2 +++
Sal. napas 40 m2 ++
Sal. cerna 400 m2 +

Adapted from McArdle WD, Katch FI, Katch VL. Exercise Physiology; 2014. Figure 12.1.
Widdicombe J. Cough. Blackwell publishing 2003; 17-23
https://elifesciences.org/articles/57309
https://pubmed.ncbi.nlm.nih.gov/32532804/
KARAKTERISTIK VIRUS
SARS CoV-2

Bakteri TBC 0,2 -0,6 μm x 1-10 μm


Virus influenza 80-120 nm
Virus SARS Cov-2 50-200 nm
RAMBUT MANUSIA 17 to 181 µm

DOI http://dx.doi.org/ 10.1016/j.cell.2020.04.013


https://elifesciences.org/articles/57309
www.azuravesta.com
DOI http://dx.doi.org/ 10.1016/j.cell.2020.04.013
PROSTAGLANDIN O2
TNF , IL 1, IL 6
CAUSES FEVER NERVE ENDINGS
CO2 STIMULANTS

+
COUGH REFLEX
HIPOKSEMIA
Sel alveolar
BRONKOKONSTRIKSI

LEUKOTRIENS SIGNALS TO
PROSTAGLANDIN NEARBY
CELLS TO ↑
Alveoli ANTIVIRAL
LYMPHOPENIA
DEFENSE

MACROPHAGE INTERFERON
CYTOKINES
ANTIBODIES ARE + DAMPs
TLR PRODUCED AGAINST
SPIKE PROTEINS MAKROFAG
SPIKE PROTEIN + ALVEOLAR
OF VIRUS NEUTROPHILS Replikasi virus
ENGULF VIRUS
T-CELL + di dalam sel
CYTOKINES
PULMONARY EDEMA TNF alveolar
PLASMA CELL IL 1
IL 6 RELEASE OF TOXIC
Surfaktan IL 8 BYPRODUCTS
DYSPNEA ALVEOLAR CHEMOKINES
HYPOXEMIA COLLAPSE
INFLAMATORY IL 8
IL 8
TNF
+ IL 1 ACUTE PHASE
INTERSTITIAL EDEMA REACTANTS:

+
TACHYCARDIA CIRCULATING ↑WBC - CRP
TACHYPNEA NEUTRPHILS
- FIBRINOGEN
- HEPCIDIN
MONOCYTE
www.azuravesta.com
BioRender (2021). Cytokine Storm. Retrieved from https://app.biorender.com/biorender-templates/figures/5e99f5395fd61e0028682c01/t-5f177d0f77526300ae48799f-cytokine-storm
BioRender (2021). Acute Respiratory Distress Syndrome (ARDS). Retrieved from https://app.biorender.com/biorender-templates/figures/5e99f5395fd61e0028682c01/t-5e9789dde5276300aad94cac-acute-respiratory-distress-syndrome-ards
https://doi.org/10.1016/j.eclinm.2020.100433, A. Hoang et al. / EClinicalMedicine 24 (2020) 100433
https://doi.org/10.3389/fped.2021.668484

https://doi.org/10.1016/j.ijid.2021.04.019
PENEGAKAN DIAGNOSIS COVD 19
PDPI, PERKI, PAPDI, PERDATIN, IDAI. Pedoman Tatalaksana COVID-19. Edisi ke-3. Desember 2020


PDPI, PERKI, PAPDI, PERDATIN, IDAI. Pedoman Tatalaksana COVID-19. Desember 2020.

PDPI, PERKI, PAPDI, PERDATIN, IDAI. Pedoman Tatalaksana COVID-19. Desember 2020.
doi:10.1001/jama.2020.8259
Courtesy of Prof.Dr. Aryati , dr., MS, SpPK (K)
BioRender (2021). COVID-19 Diagnostic Test through RT-PCR. Retrieved from https://app.biorender.com/biorender-templates/figures/5e99f5395fd61e0028682c01/t-5e8f21be13f46000ab9f6806-covid-19-diagnostic-test-through-rt-pcr
iScience. 2020 Aug 21; 23(8): 101406.
KEPUTUSAN MENTERI KESEHATAN REPUBLIK INDONESIA NOMOR HK.01.07/MENKES/3602/2021
Courtesy of Prof.Dr. Aryati , dr., MS, SpPK (K)
Diagnostics 2021, 11(1), 53; https://doi.org/10.3390/diagnostics11010053
iScience. 2020 Aug 21; 23(8): 101406.
Diagnostics 2021, 11(1), 9; https://doi.org/10.3390/diagnostics11010009
Diagnostics 2021, 11(1), 9; https://doi.org/10.3390/diagnostics11010009
https://doi.org/10.1016/j.eclinm.2020.100433, A. Hoang et al. / EClinicalMedicine 24 (2020) 100433
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https://doi.org/10.1016/j.ijid.2021.04.019
DURING THIS
COVID 19 MEDICAL

PANDEMIC,
DOCTOR

PLEASE DON’T
BE LIKE


CLASSIFICATION OF
THE SEVERITY OF
PNEUMONIA

DEFINISI TAKIPNEA
< 2 bulan : ≥ 60x/menit
2 bulan – 1 tahun : ≥ 50x/menit
1 – 5 tahun : ≥ 40x/menit
TANDA PNEUMONIA
Retraksi dinding dada (subcostal),
fremitus vokal meningkat, pekak perkusi,
suara napas melemah, dan terdengar
crackles/rales (kadang mengi)

Dpt dijumpai
“anggukkan
kepala”,
nyeri dada,
friction rub,
dan nyeri
abdomen.

Marostica PJC, et al. CAP. Dalam: Kendig and Chernick’s. Disorders of the Respiratory Tract in Children. Edisi ke-8;2012. h. 461-72.




JAMA Dermatol. 2021;157(2):207-212. doi:10.1001/jamadermatol.2020.4779
JAMA Dermatol. 2021;157(2):207-212. doi:10.1001/jamadermatol.2020.4779


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BioRender (2021). Remdesivir: Potential Repurposed Drug Candidate for COVID-19. Retrieved from https://app.biorender.com/biorender-templates/figures/5e99f5395fd61e0028682c01/t-5e8f2617bbf15200b1d93310-remdesivir-potential-repurposed-drug-candidate-for-covid-19
BioRender (2021). Favipiravir: Potential Repurposed Drug Candidate for COVID-19. Retrieved from https://app.biorender.com/biorender-templates/figures/5e99f5395fd61e0028682c01/t-5eac4dbb1b981d00b29ab1b1-favipiravir-potential-repurposed-drug-candidate-for-covid-19
Neonatology 2020;117:133–140. DOI: 10.1159/000507935


BioRender (2021). Approaches to Viral Vaccine Development. Retrieved from https://app.biorender.com/biorender-templates/figures/5e99f5395fd61e0028682c01/t-5e6256cdd7f17b0088a993d3-approaches-to-viral-vaccine-development
BioRender (2021). Common Components of Vaccines. Retrieved from https://app.biorender.com/biorender-templates/figures/5e99f5395fd61e0028682c01/t-5ec6b950af5ada00b016ccd1-common-components-of-vaccines
BioRender (2021). Clinical Phase Vaccine Candidates for COVID-19.
Retrieved from https://app.biorender.com/biorender-
templates/figures/5e99f5395fd61e0028682c01/t-
5ea83be2d3420200adea0b6a-clinical-phase-vaccine-candidates-
for-covid-19
Biologics 2021, 1(1), 2-40; https://doi.org/10.3390/biologics1010002
safe and induced
humoral

3·0 μg dose
were higher

https://doi.org/10.1016/S1473-3099(21)00319-4
Pfizer. Pfizer-Biontech announce positive topline results of pivotal COVID-19 vaccine study in adolescents. March 31, 2021. https://www.pfizer.com/news/press-release/press-release-detail/ pfizer-biontech-announce-positive-topline-results-pivotal (accessed April 27, 2021).


(Liputan6.com/Fery Pradolo)