Sie sind auf Seite 1von 38
THE SCIENCE OF HEALTH, naturally 2009 www.arkopharma.com
THE SCIENCE
OF HEALTH,
naturally
2009
www.arkopharma.com
Introduction ARKOPHARMA in brief Key dates in d’Arkopharma’s progress THE SCIENCE OF HEALTH, NATURALLY 5
Introduction
ARKOPHARMA in brief
Key dates in d’Arkopharma’s progress
THE SCIENCE OF HEALTH, NATURALLY
5
Outstanding events in 2009
2009 in figures
NATURE, EFFICIENTLY
9

Arkopharma, European leader in natural medicines Arkopharma, a healthcare company Phytotherapy, the science of plants Nutritherapy Dermopharmacy Bio Cosmetics Homeopathy and Aromatherapy

Dermopharmacy Bio Cosmetics Homeopathy and Aromatherapy CREATIVITY, SCIENTIFICALLY Seeking the best in Nature The
Dermopharmacy Bio Cosmetics Homeopathy and Aromatherapy CREATIVITY, SCIENTIFICALLY Seeking the best in Nature The
Dermopharmacy Bio Cosmetics Homeopathy and Aromatherapy CREATIVITY, SCIENTIFICALLY Seeking the best in Nature The
Dermopharmacy Bio Cosmetics Homeopathy and Aromatherapy CREATIVITY, SCIENTIFICALLY Seeking the best in Nature The
Dermopharmacy Bio Cosmetics Homeopathy and Aromatherapy CREATIVITY, SCIENTIFICALLY Seeking the best in Nature The
Dermopharmacy Bio Cosmetics Homeopathy and Aromatherapy CREATIVITY, SCIENTIFICALLY Seeking the best in Nature The

CREATIVITY, SCIENTIFICALLY

Seeking the best in Nature The latest facilities in the Service of Health Dynamic marketing at everyone’s service Graphic design

DEVELOPMENT, SUSTAINABLY

The environment’s respect Our social responsibility: to manage and develop skills

EXPANSION, INTERNATIONALLY

International Horizons Group Organisation Chart Administration, Management, Control

20
20

Arkopharma in brief

A comprehensive approach to health and well-being By adopting a comprehensive approach to health and
A comprehensive approach to health
and well-being
By adopting a comprehensive approach to health
and
well-being,
ARKOPHARMA
aims
to
meet
consumers’ expectations by providing natural
medicines, designed both to cure and to prevent,
and to encourage home medication, while at the
same time making new products available to the
medical profession for prescribing.
available to the medical profession for prescribing. ARKOPHARMA European leader in Phytotherapy and Nutritional

ARKOPHARMA

European leader

in Phytotherapy and Nutritional supplements

An International presence

in more than 60 countries

8 overseas subsidiaries:

Spain, Italy (2), Ireland, Netherlands, Belgium, Switzerland, Greece

1 202 employees

€ 177.6 million

of consolidated sales

ARKOPHARMA holds

1 724 Product Licences

for medicines.

ARKOPHARMA invests

4 % of net medicine sales in Research

and Development.

2

Key dates in ARKOPHARMA’s progress

1980 - 1982

Laboratoires ARKOPHARMA, pharmaceutical company, established. ARKOPHARMA launched Arkocaps, capsules containing whole plant powder.

1985

ARKOPHARMA introduced innovations into plant powder manufacturing procedures and established the industrial use of freeze-grinding, making it possible to retain the whole of the plant’s active principles, intact, in the finished product.

1986

The Ministry of Health recognised phytotherapy as a medicine and drafted regulations governing Product Licences for plant-based pharmaceutical products. ARKOPHARMA obtain its first registration of Arkocaps as a medicine.

1987 - 1988

ARKOPHARMA established four subsidiaries abroad: : in Spain, Italy, the USA and the UK.

1996

Introduction on the Paris Stock Exchange Second Market.

1997

ARKOPHARMA was the first pharmaceutical company to launch the 100% plant-based capsule. Steep rise in international business (+ 50%). Sales abroad accounted for 31% of consolidated net sales.

1998

Takeover of Belgian distributor, establishment of a subsidiary in the Netherlands. New factory set up in Ireland. Transformed into a Company with a Management Board and Supervisory Board.

1999

Takeover of in the USA (net sales € 7 m / FF 46 m in 1998) ); this company is well established at the 6000 points of sale in the American Health Food Channel and the US leader on the polyunsaturated oils market. Creation of BURGUNDY, firm specialized in the production of extracts of plants and natural products.

2000

Purchase of NUTRASENSE AUSTRALIA PTY Ltd (Net sales = 2.7 M€). Success of PHYTO SOYA, expert in treating menopause.

2002

Launch of PLANTE SYSTEM Laboratories and the range of 16 phytodermocosmetic products

2003

Purchase of two new subsidiaries in Switzerland: PAD and Phyto Pharma Medika. Establishment of ARKOPHARMA Canada. Success in France 4.3.2.1.Minceur, a slimming drink based on 10 plants.

2004

Mrs Colette Robert is awarded the Veuve Cliquot prize for Businesswoman of the Year 2004. International success for 4.3.2.1 MINCEUR, which becomes No. 1 product.

2005

New production unit in Italy goes on line. OPTIMAL NUTRITION range launched, a new and original range of food supplements.

2006

Transposition of European Directive No 2002/46/EC relating to food supplements on 20 th March 2006. Launch of 4.3.2.1 SLIM CHRONO, Day and Night in capsules, providing RTC, advantages, a major pharmaceutical innovation for 12-hour action. Launch of a new and original range “Plante System Bio Care”, free from chemical preservatives, free from petroleum derivatives and certified by Ecocert.

2007

Arkopharma delisted in July 17, 2007. Continuation of the action plan to improve the Group’s operating margin, with, in particular, a decrease in the product portfolio and ambitious advertising campaigns for the Group’s flagship products.

2008

Doctor Max Rombi, founder of the Arkopharma Laboratories, appointed one of his sons, Philippe 47, as the Group’s new Chairman of the Board.

2009

Our french sales networks have merged: a strategic choice for developing customer satisfaction and building strong relations.

The science of health, naturally

The science of health, naturally Our values, our strategy, our strength For more than 25 years,
The science of health, naturally Our values, our strategy, our strength For more than 25 years,

Our values, our strategy, our strength

For more than 25 years, ARKOPHARMA Laboratories

have been developing new "health medicines" based

on natural products.

In an era distinguished by a search for a healthier

life and a quest for essential values, phytotherapy

and food supplements are gaining ever-increasing

support from consumers worldwide.

5

Outstanding events in 2009 And, what’s new in 2010 In France, our sales networks have
Outstanding events in 2009 And, what’s new in 2010 In France, our sales networks have
Outstanding events in 2009
And, what’s new in 2010
In France, our sales networks have merged:
New products have been added to the different product lines, which are
a strategic choice for developing customer satisfaction
and building strong relations.
already widely known and recognized for their high quality and leading
position on their respective markets, such as:
In 2009, the ARKOPHARMA and ARKOMÉDIKA sales networks merged
into one single ARKOPHARMA network, comprised of 90 sales
representatives
This
merger
was
implemented
in
order
to
optimize
the
sales
performance of the Arkopharma Group, with the following goals:
- To boost the effectiveness of future product launches and secure
a foothold for the Group’s leading product lines in pharmacies,
- To increase the number of client pharmacies,
- To reduce the sales representatives’ sectors and thus increase the
number of pharmacy visits,
- In the ARKOCAPS line: ARKOLUTEINE (helps fight against eye strain),
- To lower management expenses and delivery charges,
ARKOLEVURE (helps restore balance to the intestinal flora), MACA
- To establish the Group’s position as European leader in the field of
Phytotherapeutic remedies and dietary supplements.
(physical and intellectual stimulation), SERENOA REPENS (urinary
comfort),

On a Commercial level, this merger brought together 90 sales representatives in the same network to create an increasingly dynamic sales force. The sales sectors were divided up in a new manner for more effective client follow-up.

On a Marketing level, this operation has consolidated the ARKOPHARMA and ARKOMÉDIKA product portfolios and will help redefine the strategic choices for the Group’s leading brands.

This merger has enabled us to improve the quality of the services we offer our pharmacy clients and thus consolidate customer relations, which were already optimized, thanks to the deployment of the CRM (Customer Relationship Management) tool that was finalized in 2009.

And, with the goals of developing lasting relations with our pharmacy clients, the sales promoter network expanded this year with a view to better meeting pharmacists’ needs in terms of product training and merchandising support.

Product development that meets consumers’ needs.

The new product lines that were launched in 2009 proved to be highly

successful both with pharmacists and consumers. This was the case for the

ARKOBIO TABLETS and ARKOBIO HERBAL tea lines, which combine 100%

Organic and Ecocert certified plants that offer all of the benefits of nature

in different dosage forms, and the ARKOLÉOL line that helps burn and

eliminate fat.

and the ARKOLÉOL line that helps burn and eliminate fat. - In the ARKO ROYAL line:
and the ARKOLÉOL line that helps burn and eliminate fat. - In the ARKO ROYAL line:
and the ARKOLÉOL line that helps burn and eliminate fat. - In the ARKO ROYAL line:
and the ARKOLÉOL line that helps burn and eliminate fat. - In the ARKO ROYAL line:

- In the ARKO ROYAL line: tablets combining Royal Jelly and Vitamins,

a SYRUP FOR RESPIRATORY COMFORT, a combination of Royal Jelly

and probiotics,

- In the CHONDRO-AID line: RESTRUCTURING CHONDRO-AID with a

collagen base (to regenerate and strengthen the articular cartilage),

base (to regenerate and strengthen the articular cartilage), - In the CYS-CONTROL line: new dosage forms
base (to regenerate and strengthen the articular cartilage), - In the CYS-CONTROL line: new dosage forms

- In the CYS-CONTROL line: new dosage forms (capsules, effervescent tablets),

- In the PLANTE SYSTEM COSMETIC line: Organic lip balm, eye contour gel, creams that protect the skin from cold weather…

And many more

that protect the skin from cold weather… And many more In 2010 , we will launch
that protect the skin from cold weather… And many more In 2010 , we will launch

In 2010 , we will launch a new ARKOPROBIOTICS line on the probiotics market, which is a rapidly growing sector (+30%) . This line will include three products packaged in innovative small bottles and will be highlighted in pharmacies inside refrigerated display units, furnished by ARKOPHARMA, which will help optimize the quality and conservation of the probiotic-based products

Other new products will be launched throughout the year on different buoyant segments in order to continue to best meet consumer needs.

A dynamic Internet policy for both consumers and clients. The Group’s Internet site (www.arkopharma.com) enables
A dynamic Internet policy for both consumers and clients. The Group’s Internet site (www.arkopharma.com) enables

A dynamic Internet policy for both consumers and clients.

The Group’s Internet site (www.arkopharma.com) enables users to view the main product lines manufactured by the ARKOPHARMA laboratories in France and abroad as well as access the websites of the Group’s different subsidiaries.

The Frenchwebsite (www.arkopharma.fr) has beenentirely redesignedand now boasts a new, more attractive and modern ergonomy. Moreover, the pharmacists can now rapidly and easily place their replenishment orders on-line. At the same time, a “Commercial Development” unit was set up to manage the Internet orders and challenges in pharmacies

On an international level, a restructuration that has been successful since 2009.

The closure of our non-strategic subsidiaries (Germany, Canada, England), which were often in deficit, combined with a disposal of assets policy (USA, Australia) have allowed us to significantly improve the contribution and performance of the Group’s international activities. This strategy of refocusing the subsidiaries’ business activities on Europe will be continued throughout the following years.

of refocusing the subsidiaries’ business activities on Europe will be continued throughout the following years. 8

Nature, efficiently

A philosophy
A philosophy
Nature, efficiently A philosophy Phytotherapy and nutrition therapy, those natural medicines, provide a

Phytotherapy and nutrition therapy, those

natural

medicines,

provide

a

particularly

good

solution

to

the

“ills

of

civilisation”

brought

on

by

stress,

poor

diet

and

an

unhealthy lifestyle. They meet the need to

“feel good” and to keep in shape, one of the

aspirations

most

strongly

felt

developed societies.

in

our

9

ARKOPHARMA, European leader in natural medicines

Preventing and curing, naturally, efficiently and safely.

For more than 20 years, the Arkopharma Group has demonstrated its creativity and innovatory flair, directing its research and development entirely towards humans, their health and their well-being.

Nowadays, French enthusiasm for natural treatments is equalled in all developed countries, where there is increasing mistrust of chemical medicines. This is more than a fashion, it reflects a deep desire for a return to nature, intensified by the disclosure of side-effects, perhaps even toxic, caused by some chemical medicines.

This situation explains the success enjoyed by phytotherapy, dietetics, nutritherapy and homeopathy, which satisfy the lasting need felt by consumers seeking balanced, natural and healthy living.

These “health products” developed by the Arkopharma Group meet two requirements: prevention and cure while maintaining the body’s equilibrium and treating the root cause rather than the symptom. They enable consumers to take charge of their own health, with all the product quality and safety guarantees that can be provided by a pharmaceutical company.

The launch, in 1997, of 100% plant-based capsules provided an additional guarantee and reassured consumers concerned for their health.

The constant advances made in phytotherapy, particularly the identification of new active principles, new pharmacological properties and the performance of numerous clinical trials validating the efficacy of the treatments, have contributed to the success of this “other

treatments, have contributed to the success of this “other medicine”   45,000 DOCTORS IN FRANCE (Source

medicine”

 

45,000 DOCTORS IN FRANCE

(Source ICOMED datas)

say they prescribe natural medicines

WHAT DOES ARKOPHARMA REPRESENT IN FIGURES?

 

With a catalogue of more than 1000 non-reimbursable products, ARKOPHARMA covers every sphere of self-

medication. On the nutritional supplements market, (without product licences for medicine and non-reimbursable self-

   

medication), representing € 46.9 m, ARKOPHARMA leadingplace, holdinga 15.7 %market share.

has a

(Source: IMS nutritional supplements, sell out- dec. 2008)

   
ARKOPHARMA, a healthcare company A diversified range comprising more than 1000 lines makes it possible
ARKOPHARMA, a healthcare company
A diversified range comprising more than 1000 lines makes it possible to cover all self-medication areas.
The market for sun protection in capsules
The 12 main markets per indication
(Source: year 2009 Nutritional Supplements in pharmacy)
(Sales pharmacy units 43,2 m/year)
(Source: base IMS Nutritional Supplements in pharmacy,
PM volume - CMA december 2009)
Arkopharma
17.6 %
Slimming
22.4 %
Œnobiol
34.4 %
Tonic
21.3 %
Naturactive
17.6 %
Immune systems
9.5 %
Forte Pharma
5.3 %
Stress
9.0 %
Noreva Pharma
4.3 %
Hair care
5.8 %
Others
20.8 %
Bone remineralizer
5.2 %
Ophtalmology
Gyneco and urinary problems
5.0 %
4.9 %

The market for slimming

(Volume: year 2009) (Source: Nutritional Supplements IMS)

(Volume: year 2009) (Source: Nutritional Supplements IMS) Arkopharma 13.5 % Phythea 14.5 % Forte

Arkopharma13.5 %

13.5 %

Phythea14.5 %

14.5 %

Forte Pharma12.9 %

12.9 %

Œnobiol10.3 %

10.3 %

Omega Pharma Franc5.8 %

5.8 %

Others43.0 %

43.0 %

The market for hair case

(Share market in pharmacy - Year 2009) (Source: IMS base Nutritional Supplements)

Arkopharma 20.9 % Œnobiol 21.7 % Furterer 9.5 % Ducray 9.6 % Naturactive 4.3 %
Arkopharma
20.9 %
Œnobiol
21.7 %
Furterer
9.5 %
Ducray
9.6 %
Naturactive
4.3 %
Others
34.0 %

Sun protector3.5 %

3.5 %

Menopause2.9 %

2.9 %

Circulation (range)2.8 %

2.8 %

Skin2.8 %

2.8 %

Others4.9 %

4.9 %

The market for tonics in pharmacy

(Share market in pharmacy - Year 2009) (Source: IMS base Nutritional Supplements)

- Year 2009) (Source: IMS base Nutritional Supplements) Arkopharma 24.2 % Bayer Sante Famil 14.9 %

Arkopharma24.2 %

24.2 %

Bayer Sante Famil14.9 %

14.9 %

Urgo Soins & Santé8.0 %

8.0 %

Menarini7.3 %

7.3 %

Merck MF6.4 %

6.4 %

Others39.2 %

39.2 %

The market for menopause in pharmacy

(Volume: december 2009)

market for menopause in pharmacy (Volume: december 2009) Phyto Soya/Arkopharma 13.9 % Theramex 9.2 %

Phyto Soya/Arkopharma13.9 %

13.9 %

Theramex9.2 %

9.2 %

Omega Pharma12.0 %

12.0 %

Noreva Pharma14.1 %

14.1 %

Nutrisante10.0 %

10.0 %

Others40.8 %

40.8 %

11

Phytotherapy, the science of plants

The Group ARKOPHARMA always used the most modern technology to allow the phytotherapy to stand out as a full medicine.

Freeze grinding.

Medicinal plants contain thousands of constituents, all potentially active and acting synergetically. In order to make the best use of them, ARKOPHARMA has developed the use of the whole powder of the active part of the plant.

After strict, rigorous selection of plants and performing numerous botanical, bacteriological and physico-chemical controls ensuring perfect quality and optimum efficacy, the plants are freeze ground in a nitrogen atmosphere at –196°.

Using this efficient technique, ARKOPHARMA has been able to ensure total efficacy. Freeze grinding makes it possible to retain the whole of

technique, ARKOPHARMA has been able to ensure total efficacy. Freeze grinding makes it possible to retain
The 100% plant-based capsule.
The 100% plant-based capsule.

the plant, to ensure a high active principle content and to obtain a particularly fine particle size, making assimilation easier and improving bioavailability.

   

It is ARKOPHARMA’s incessant innovative thrust and its quest for ever-better quality that enabled it quickly to

   

become No. 1 in phytotherapy in France.

The scientific value of its products is officially recognised,

since

ARKOPHARMA holds more than

213

Product Licences for

phytotherapy medicines, issued by the Agence

 

Française de Sécurité Sanitaire des Produits de Santé

(French Health Product Safety Agency).

In 1997, ARKOPHARMA made news by offering the first range of 100% plant-based products, thus confirming its status as phytotherapy leader:

indeed, in that year, the gelatin traditionally used for the capsule shell was replaced by a natural substitute of vegetable origin, a cellulose derivative. Cellulose surrounds and protects the cells of all plants.

The 100% plant-based capsule is entirely natural and contains no gluten or preservatives.

More than 120 DIFFERENT KINDS OF ARKOCAPS, that’s what ARKOPHARMA offers in phytotherapy
More than
120 DIFFERENT KINDS OF ARKOCAPS,
that’s what ARKOPHARMA offers in phytotherapy
ARKOBIO TABLETS… 4 ORGANIC plants in one tablet. A line made up of 6 ORGANIC
ARKOBIO TABLETS… 4 ORGANIC plants in one tablet. A line made up of 6 ORGANIC
ARKOBIO TABLETS…
4 ORGANIC plants in one tablet.
A line made up of 6 ORGANIC products, which offers a well-adapted
solution for all needs:
- ARKOBIO JOINTS: White Willow, Black Currant, Nettle and
Meadowsweet for greater articular flexibility.
- ARKOBIO DIGESTION: Anise, Fennel, Rosemary and Angelica for
improved digestion.
- ARKOBIO DETOX: Black Radish, Artichoke, Dandelion and Linden
Bark to purify the body.
- ARKOBIO FOR TIRED HEAVY LEGS: Red Vine, Cypress, Horse
Chestnut and Ruscus for energize tired, heavy legs.
The ARKOCAPS range.
- ARKOBIO WEIGHT LOSS: Green Tea, Grape Pomace, Birch and
Cherry Stem to slim down the figure.
With more than 120 products covering the principal indications for self-
medication, this line, which has been the leader of its market for many
years, is one of the ARKOPHARMA Group’s flagship lines. Its concept: one
plant/one capsule.
- ARKOBIO REST/SLEEP: Passion Flower, Lavender, Bitter Orange and
Hawthorn to help you rest and relax.
ARKOBIO HERBAL TEAS
Thanks to ARKOCAPS and informed advice from pharmacists, everyone
is now able to naturally treat his or her minor ailments.
100% environmentally-friendly, the plants used in the ARKOBIO herbal
teas are entirely ORGANIC and ECOCERT certified. These naturally
effective herbal teas offer you all the benefits of nature.
New highly promising plants have been added to the line, such as:

- MACA ARKOCAPS, help stimulate physical and intellectual strength and capacity in men and women

- ARKOLUTEINE ARKOCAPS combine natural ingredients, such as

lutein and xanthophylls to help protect the eyes and improve visual acuity.

- CARBON YEAST ARKOCAPS, a complete combination of botanical

carbon, revivifiable yeast Saccharomyces boulardii and Inulin, which are beneficial for digestion and intestinal comfort.

- SERENOA REPENS ARKOCAPS which improve urinary elimination and thus help restore urinary comfort.

urinary elimination and thus help restore urinary comfort. This line includes the following 4 products: -

This line includes the following 4 products:

- ARKOBIO INFUSION Sleep and Relaxation

- ARKOBIO INFUSION Detox

- ARKOBIO INFUSION Digestion

- ARKOBIO INFUSION Elimination

THE 4.3.2.1 SLIM LINE

The Arkopharma Laboratories have created new, highly innovative products:

- 4.3.2.1 SLIM CALORIATTACK: thanks to satioappetil®, an exclusive

complex comprised of 4 natural active ingredients, this new “all in one” weight loss sachet helps you resist overeating by diminishing hunger pangs.

- 4.3.2.1 SLIM TEACTIVE: a delicious herbal weight loss tea, which is comprised of 9 certified organic plants.

4.3.2.1 SLIM DIETPERFECT: a line of low calorie snacks with plant proteins that offers 7 original and delicious flavors.

And of course, the essentials from the 4.3.2.1 SLIM line:

- 4.3.2.1 SLIM ULTIMATE: the most highly concentrated formula on

the market in active botanical slimming ingredients, which comes in the form of a triple layer tablet.

- 4.3.2.1 SLIM DRAINEUR: a solution comprised of 99% botanical

aqueous extracts, which have been clinically proven effective.

- 4.3.2.1 SLIM DRAINEUR BIO: the expertise and effectiveness of 4.3.2.1 Slim, in an ORGANIC version.

- 4.3.2.1 STARTER SLIM: a complete formula that comes in a small

bottle, which is ideal for active women who want to maintain their shapely figure.

- 4.3.2.1 SLIM FOR MEN: a composition that is specially adapted to individuals who wish to burn fat, yet retain their muscle.

ARKOFLUIDS

CYS-CONTROL

Cranberry’s anti-adhesion properties, recognized by the French Authorities, are at the heart of CYS-CONTROL’s action. To better meet the needs of all consumers, CYS-CONTROL now comes in two different forms.

CYS-CONTROL capsules, which provide 36 mg of proanthocyanidins, the effective dose recommended to combat fixation by bacteria to the walls of the urinary tract and thus control urinary discomfort and its recurrence.

Three dosage forms are available: capsules, sachets and effervescent tablets.

ACEROLA 1000 CHEWABLE TABLETS
ACEROLA 1000 CHEWABLE TABLETS

Created by the ARKOPHARMA Laboratories’ research department, this line of Certified Organic oral ampoules, formulated without preservatives, alcohol, artificial colors or flavors, is made with natural active ingredients.

There are currently eleven products available: Joints; Urinary Comfort; Relaxation; Detox; Digestion; Tired Heavy Legs; Memory; Weight Loss Program; Black Radish; Stimulant; Weight Loss Synergy.

BAKOL FORT

BAKOL FORT,

cholesterol both of dietary origin and produced by the body. This combination of phytosterols and policosanols is one of the most effective natural alternatives for statin intolerant individuals.

natural alternatives for statin intolerant individuals. is a formula to combat ARTROPHYTUM This is a

is

a formula to combat

ARTROPHYTUM

This is a Harpagophytum-based remedy, which relieves articular pain and offers a genuine alternative to classic anti-inflammatory drugs, without the side effects.

The ACTIVOX LINE

This line provides a pharmaceutical solution suited to each type of ORL disorder, thanks to a wide range of capsules, gums, pastilles, syrups, mouth-washes, inhalers, tablets for inhalation and pomades. The new products added to the line in 2009 are:

- ACTIVOX PASTILLES ACEROLA, that contain Erysimum, which is

known for its soothing action on the throat.

- ACTIVOX SPRAY which soothes the throat and is formulated with Erysimum, Chamomile, Honey, Thyme and Propolis.

with Erysimum, Chamomile, Honey, Thyme and Propolis. Acerola is the fruit of a small shrub found

Acerola is the fruit of a small shrub found in Central America that can contain 20 to 80 times more vitamin C than citrus fruits. ACEROLA 1000, a delicious chewable tablet with a fresh taste containing 1000 mg of concentrated ACEROLA extract, offers an exceptionally high concentration of natural vitamin C. Two dosage forms are available:

chewable tablets or effervescent tablets, both of which contain a concentrated extract of Acerola, i.e. 180 mg of natural vitamin C.

PHYTO SOYA THE EXPERT IN TREATING MENOPAUSE, NATURALLY

The PHYTO SOYA line provides women with a natural solution for treating unpleasant menopausal symptoms: PHYTO SOYA “Standard Formula” 17.5 mg, PHYTO SOYA “Intensive Formula” 35 mg, Phyto Soya “Expert Formula”, PHYTO SOYA Age Minimizing Cream and PHYTO SOYA Vaginal Gel. The effectiveness of the line’s dietary supplements (which offers a significant decrease in hot flashes) as well as the safety of the extract used in terms of the breasts and endometrium has been clinically proven. These studies were published in international publications.

Nutritherapy

AZINC RANGE

There are times in life when our body shows a deficiency in vitamins and minerals, nutrients that are essential for the body to function properly. The AZINC range was specially designed to remedy such deficiencies and comes in several pharmaceutical forms (capsules, chewable tablets, effervescent tablets and syrup).

New products: AZINC PROBIOTICS FOR ADULTS, which is formulated with Propolis extract, 3 probiotics, 12 vitamins, 7 minerals and trace elements, stimulates our body’s natural defenses. AZINC PROBIOTICS FOR SENIORS, which is formulated with plant extracts, lutein, CO-E Q10, 2 probiotics, 12 vitamins, 7 minerals and trace elements, helps men and women over the age of 50 stay healthy, boosts vitality and improves memory.

What’s new? RESTRUCTURING CHONDRO-AID, which is formulated with collagen hydrolysat and hyaluronic acid, helps strengthen the articular cartilage.

1 : Clegg & al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis, N Engl J Med. 2006 Feb 23; 354 (8): 795-808

ARKO ROYAL HIVE
ARKO ROYAL HIVE
N Engl J Med. 2006 Feb 23; 354 (8): 795-808 ARKO ROYAL HIVE THE ARKOLEOL LINE

THE ARKOLEOL LINE

The NEW GENERATION of fat burners

ARKOLEOL is a triglyceride-free product line that is rich in unsaturated free fatty acids, which helps break down and eliminate stored fat, by:

- supplying energy that may be directly used by the body

- targeting the heart of the cell in order to burn and eliminate stored fat

Honey, Royal Jelly and Propolis: these natural substances have exceptional properties. Discover all of their healthcare benefits, thanks to the Royal Hive line from the ARKOMEDIKA Laboratories. This line offers a wide choice of products that meet the needs of the entire family: ROYAL JELLY Ampoules, DYNERGIE, Propolis, 100% ROYAL JELLY, PASTILLES and Propolis spray, syrups for children…

Two new products:

- ARKOROYAL ROYAL JELLY + PROBIOTICS, a combination of

lyophilized royal jelly and probiotics packaged in a small bottle that boosts energy, stimulates the body’s natural defenses and restores balance to the intestinal flora.

This product comes in 2 versions: a program for adults and a program for juniors

- ARKOROYAL ROYAL JELLY + GINSENG: This energizing formula

combines 2 sources of energy for extensive healthcare action.

The ARKOLEOL program:

- To get your day off to a great start: ARKOLEOL SACHETS

- To continue the program all day long: ARKOLEOL CAPSULES

- To enhance your meals: ARKOLEOL DIETETIC AND HEALTHY OIL

CHONDRO-AID FORT

A natural solution with a glucosamine and chondroitin base that helps fight against the deterioration of cartilage and restore articular mobility.

The development of this formula and choice of specific doses were based on the results of the GAIT1study, which proves the level of effectiveness of this specifically dosed active ingredient combination that helps restore comfort and articular mobility.

SEROXYL

SEROXYL, developed by the Arkopharma Laboratories, is ideal for fighting against anxiety, stress and mental fatigue. This composition includes an optimal dose of L-Tryptophan, which naturally plays a role in the production of serotonin, an element that is essential to emotional balance and well-being. It is combined with vitamin B6, which promotes relaxation, particularly during moments of overwork.

BETASELEN A combination of vitamin C, vitamin E, beta-carotene, zinc and selenium to fight against
BETASELEN A combination of vitamin C, vitamin E, beta-carotene, zinc and selenium to fight against
BETASELEN
A combination of vitamin C, vitamin E, beta-carotene, zinc and selenium
to fight against free radicals, which are responsible for cell and tissue
ageing, in the case of fatigue.
ARKOVISION
A combination of nutrients with antioxidant properties, LUTEIN AND
XANTHOPHYLLS, which help protect the retina and crystalline lens from
oxidative reactions that may be triggered by cigarette smoke, exposure
to the sun, pollution, aging…
ARKOPROBIOTICS
A brand new product line of probiotics that restores balance to the body
and stimulates its natural defenses:
- ARKOPROBIOTICS DEFENSES Adults, packaged in small bottles,
which contain 10 billion probiotics,
- ARKOPROBIOTICS DEFENSES + Adults packaged in Sachets, which
contain 50 billion probiotics,
- ARKOPROBIOTICS DEFENSES JUNIOR, packaged in small bottles,
which contain 5 billion probiotics.
in small bottles, which contain 5 billion probiotics. SLIMEXCELL Three new slimming products that meet the

SLIMEXCELL

Three new slimming products that meet the needs of women:

- SLIMEXCELL PROBIOTIC BALANCE WEIGHT LOSS and SLIMEXCELL

PROBIOTIC BALANCE WEIGHT LOSS 45+: These 2 formulas contain grape pomace extract combined with balance-restoring probiotics, to restore intestinal comfort, burn fat and drain toxins from the body.

- SLIMEXCELL CONCENTRATE ANTIOXIDANT TISSUE DRAINER is a

highly concentrated product that comes in an innovative dosage form, with a practical dropper that releases a body contouring plant concentrate and antioxidant pomegranate juice.

ARKOLEVURE

A dual active formula (Probiotics and a Prebiotic) that helps the body maintain balance in the intestinal flora and stimulates the body’s natural defenses. Comes in capsules and sachets.

maintain balance in the intestinal flora and stimulates the body’s natural defenses. Comes in capsules and
maintain balance in the intestinal flora and stimulates the body’s natural defenses. Comes in capsules and
Dermopharmacy SUN PROTECTION: THE PHYTOBRONZ LINE Primrose and Argan oils as well as carotenoids and
Dermopharmacy SUN PROTECTION: THE PHYTOBRONZ LINE Primrose and Argan oils as well as carotenoids and
Dermopharmacy
SUN PROTECTION: THE PHYTOBRONZ LINE
Primrose and Argan oils as well as carotenoids and vitamin E), this capsule
helps the skin maintain a natural radiant golden glow all year round.
To take full advantage of the sun’s benefits without suffering its
drawbacks, the skin must be prepared for exposure to sunrays.
PHYTOBRONZ thus offers: PHYTOBRONZ for fair, sensitive skin: this
formula, created for the most delicate skin types, helps activate the
skin’s natural tanning process and protects it from cellular ageing.
PHYTOBRONZ for dark, sensitive skin: this exclusive and complete
formula, with a natural carotenoid base (carotene and lutein), wheat
berry oil (rich in ceramides), natural silica and vitamin A, helps activate
the skin’s natural tanning process, replenish moisture and protect dark,
sensitive skin.For complementary action, use PHYTOBRONZ Sublime Oil,
which triggers, intensifies and prolongs a natural tan, leaving the skin
with a beautiful satiny golden glow.
HAIR CARE: FORCAPIL
FORCAPIL Capsules are not only market leader, they provide the most
complete combination of active principles on the market: this formula
And, SKIN PEARL HYALURONIC ACID, which contains 120 mg of
combines sulfurated amino acids, zinc and vitamin D3 with the vitamin
hyaluronic acid and helps the skin improve its level of moisture, elasticity
and firmness from within.

B

“All in one” action: anti-hair loss, fortifying and volume-enhancing, with clinically proven* effectiveness. Test results show a 66.5% decrease in hair loss after 6 months of product use.

The most recent new product: FORCAPIL FOR MEN. This formula, formulated with cystine, methionine, biotin, vitamins B5 and B6, Serenoa

repens and zinc, directly target the hair roots and helps prevent hair loss.

It increases the hair’s level of resistance and density and helps regulate the excess production of sebum

* Clinical study 2008 – ref 4757-77-E3

complex to remedy problems affecting hair and nails.

complex to remedy problems affecting hair and nails. BEAUTIFUL SKIN: THE SKIN PEARL LINE To nourish

BEAUTIFUL SKIN: THE SKIN PEARL LINE

To nourish your skin from within and prevent premature signs of cutaneous ageing: MOISTURIZING SKIN PEARLS, for women who wish to maintain radiant

Two new products have been added to the SKIN PEARL line: SKIN PEARL SUN-KISSED RADIANCE, for a healthy golden glow all year round. Thanks to its concentration of natural active ingredients (Borage, Evening

LICE CONTROL

ALTOPOU is a complete line of products to prevent and eliminate nits and lice: ALTOPOU DIMETICONE LOTION, ALTOPOU REPELLENT, ALTOPOU CLOTHING, ALTOPOU ENVIRONMENT and ALTOPOU SHAMPOO with 100% pure and natural essential oils to alleviate itching and repel parasites.

STICKS

TRAVELLER, a combination of essential oils to soothe and refresh in the case of motion sickness, sea sickness and mountain sickness without causing drowsiness.

VERRUSTICK, an effective formula containing essential oils, to eliminate common warts.

MIGRASTICK, clinically-proven effectiveness in relieving headaches.

clinically-proven effectiveness in relieving headaches. FITACNOL, containing essential oils to heal and cleanse.

FITACNOL,

containing essential oils to heal and cleanse.

ASIA-STICK, a thousand-year-old formula to relieve pain.

product

the

“anti-spot”

MOSQUITOX STICK, a roll-on stick for the immediate relief of mosquito bites.

X-ERPASTICK, to soothe burning sensations in cold sores.

BACTISEPTIC

An antiseptic hand gel, which combines disinfectant properties with Aloe Vera to maintain moisture.

Bio Cosmetics In 2009, PLANTE SYSTEM tripled the number of its points of sale, which
Bio Cosmetics In 2009, PLANTE SYSTEM tripled the number of its points of sale, which
Bio Cosmetics
In 2009, PLANTE SYSTEM tripled the number of its points of sale, which
confirmed the brand’s buoyant growth and the success of its new
products:
- TINTED MOISTURIZING EMULSION received a "BEAUTY AWARD" in 2009,
after having been tested and approved by a jury of independent
consumers.
- LIP CARE STICKS,
These genuine lip care treatments, in the form of sticks, contain no Vaseline
or paraffin. Day after day, they nourish and soften the lips, thanks to bee’s
wax and plant oils. Four active ingredients, four fragrances: nourishing lip
care with Argan oil, Anti-age lip care with Orchid, Regenerating lip care
with Gold of Pleasure and Colorful lip care with Lotus.
This skincare emulsion, which is lightly tinted, thanks to natural
pigments, restores moisture to the skin, helps diminish our first wrinkles
and adds an instant natural golden glow to the skin, without leaving
- MOISTURIZING PRODUCTS WITH EDELWEISS,
This precious skincare, which is rich in rare and precious active
ingredients, such as Edelweiss and Antarticine, protects the skin and
provides it with long-lasting moisturization. Two products are available:
Light Moisturizing Cream with Edelweiss for dry skin and Moisturizing
Fluid with Edelweiss for normal skin
- ANTI-WRINKLE AND ANTI-DARK CIRCLE EYE CONTOUR PRODUCTS
These products use the very best of nature to treat the eye contour

(Formulated without fragrance and essential oils, hypoallergenic and tested on contact lens wearers):

• Formulated with Arnica, cornflower water and hyaluronic acid, the

anti-dark circle gel diminishes dark under eye circles and reduces signs of fatigue.

• Formulated with Acacia Senegal (also called Acacia collagen),

Wheat and Ruscus glucosides, the lifting anti-wrinkle balm diminishes wrinkles and crow’s feet as well as softens the skin.

wrinkles and crow’s feet as well as softens the skin. On an international level, Plante System

On an international level, Plante System has proven to be successful in China, the Netherlands and Spain. In the very near future, it will be launched on new major markets, such as Russia, Brazil and Germany.

and Spain. In the very near future, it will be launched on new major markets, such
and Spain. In the very near future, it will be launched on new major markets, such

Homeopathy and Aromatherapy

HOMEOPATHY

The ARKOPHARMA Group has been present on the homeopathy market since 1991 (the year when it took over LABORATOIRES HOMEOPATHIE FERRIER) with:

- A range of FERRIER mother tinctures (reimbursed medication),

comprised of 30 products, manufactured from strictly controlled raw materials.

- A range of OTC homeopathic products including the new TABAPASS,

a real alternative for helping individuals break the nicotine addiction

- A line of the most widely prescribed and recommended polychrests, granules and doses, such as Arnica montana, Nux vomica, Ignatia amara, Gelsemium, Rhus toxicodendron, Chamomilla… as well as Influenzinum, which is used for preventing influenza states and influenza syndromes, has been hugely successful with over 2 million doses sold in 2009.

- The 30 ABBE CHAUPITRE formulae, homeopathic drops, cover many indications and arouse lively interest in consumers, particularly formula 6 (vertigo-migraines) and 7 (Minor sleep disorders – temporary periods of anxiety)

AROMATHERAPY

In line with its natural healthcare approach, the Arkomedika Laboratories chose to develop an aromatherapy range, launching 100% pure and natural ARKENTIAL essential oils that are non-deterpenated and

manufactured in compliance with the most rigorous specifications in effect.
manufactured in compliance with the most rigorous specifications in
effect.
compliance with the most rigorous specifications in effect. In order to meet growing consumer demands, 6

In order to meet growing consumer demands, 6 new Organic essential oils will be added to the ARKENTIAL line in 2009: lemon, eucalyptus, lavender, mint, tea tree, thyme, and a new derivative products will be launced in 2010 (sprays, capsules,…).

and CONTUSIUM, a stick comprised of botanical ingredients (Arnica, Melilotus and Hypericum) to relieve knocks, bumps and bruises, which has just been added to the line of topical remedies.

which has just been added to the line of topical remedies. - This line also includes:

- This line also includes: ANXIETUM sublingual tablets against stress and anxiety, AFTOSIUM to treat ailments of the buccal cavity, SLIMUM as an adjuvant to weight loss diets, NAUSETUM against travel sickness and nauseous states, VEINOSIUM, to treat

) and NOCTIUM for the

hemorrhoids and soothe tired, heavy legs ( management of sleep disorders in children.

to treat ) and NOCTIUM for the hemorrhoids and soothe tired, heavy legs ( management of

Creativity, scientifically

the many fruits of effective research
the many fruits
of effective research
scientifically the many fruits of effective research With strict selection of starting materials, clinical trials

With strict selection of starting materials, clinical

trials and the development of new manufacturing

technologies, ARKOPHARMA introduces something

new every year and offers products of impeccable

quality.

They are backed by efficient marketing, alert to

what consumers, pharmacists and doctors are

saying.

20

Seeking the best in nature

NEW REGISTRATIONS

PHYTOTHERAPY PRODUCTS

NEW INTERNATIONAL PRODUCT LICENSES The registration program for medicine continued on an International level, where a product license for ARKOCAPS HARPADOL was obtained for the United Kingdom, Portugal, Greece and Serbia. A product license was registered in Turkey for PROCALMIL.

Product licenses were obtained for different products in several South American countries: PHYTOSOYA 17.5mg in Ecuador, PHYTOSOYA 35 mg

in Chili, ARTROFITUM in Colombia and the CYS-CONTROL sachet in Peru.

In Madagascar, product licenses were obtained for the following medicine: ARKOCAPS CAMILINE, ARKOCAPS VALERIAN AND ARKOCAPS RED VINE.

A FOCUS ON THE 2011 PRODUCT LICENSES AND EUROPEAN LICENSES

DIETARY

OTHER PRODUCTS

337 international applications for registration were filed.

PRODUCTS

/

DIETARY

SUPPLEMENTS

/

COSMETICS

The notification/registration policy for the PLANTE SYSTEM line

and other cosmetic products was continued in numerous

countries throughout the world.

NEW PRODUCT LAUNCHES

DIETARY PRODUCTS AND DIETARY SUPPLEMENTS

THE ARKOLEOL® PROGRAM

ARKOLEOL® SACHETS: a powder that is very rich in unsaturated fatty

acids (20%), which comes in the form of ethyl esters without glycerol

PROGRAMS

The European Directive 2004/24/CE for traditional herbal medicinal products had major consequences on ARKOPHARMA. It requires that our company respect the European standards and that all of our MAN phytotherapy applications for registration be refiled before January

2011 in France. It is a matter of protecting and, in particular, developing the product licenses for the ARKOCAPS line, which is an important part

of our company’s portfolio.

Within the framework of this program, 23 ARKOCAPS applications for registration were filed in 2009. The rest of the applications will be filed before January 2011, including the ACTIVOX line, amongst others.

ARKOPHARMA is by far the Laboratory that has filed the highest number

of this type of updated applications at the AFSSAPS (French agency for

the sanitary security for health products)

Spain: 25 ARKOCAPS applications for registration were updated for the Spanish subsidiary, the Group’s leading subsidiary in terms of turnover.

7 applications for registration were sent to the main subsidiaries and most important distributors, beginning with the most promising ARKOCAPS products in terms of sales. 16 new applications for registration were budgeted for the European zone in 2010.

These applications were also filed for overseas export. Phytotherapy has always represented the foundation of our business activity and Laboratory expertise.

HOMEOPATHIC PRODUCTS

NEW APPLICATION FOR REGISTRATION IN FRANCE

In homeopathy, a new preparation has been registered: Alfalfa.

Thanks to the success that the Ferrier homeopathic units line showed in 2009 and with a goal to always optimally respond to our clients’ needs, 3 new applicationsforregistrationwerefiled(pulsatilla, influenzinumandginseng) and a dozen new developments were continued or initiated during 2009.

and is dispersible in water.

This product promotes the regulation of lipidic and glucidic metabolism,

breakdown of fatty deposits and elimination of stored fat, made up of

triglycerides.

A special milk protein absorption procedure was developed for this

formulation.

ARKOLEOL® DIETETIC AND HEALTHY OIL: this excellent seasoning oil,

which is comprised of fatty acids from olive oil in the form of ethyl

esters, allows you to delectably season your dishes without using

triglycerides. Having the same properties as the ARKOLEOL powder

sachet, this Dietetic and Healthy Oil allows to you effectively fight

against the metabolic syndrome.

A well-adapted industrial filtration system is used to manufacture this

oil, which separates the pieces of olive leaves and fruit that are in contact

with the fatty acids in order to improve its organoleptic characteristics.

EXPERIMENTAL STUDY

The ARKOPHARMA Laboratories have conducted an experimental study

on rats in order to compare the impact on the level of blood triglycerides

in the oils used for the ARKOLÉOL® sachets (ethyl oleate) and

ARKOLÉOL® capsules (omega-3 fatty acid esters), as compared to

ordinary olive oil (fatty acids in the form of triglycerides).

As expected, the use of classic olive oil causes the level of plasmatic

triglycerides to increase between the beginning and end of the study,

whereas the unsaturated free fatty acids, used in the ARKOLÉOL®

products, does not lead to a rise in the level of triglycerides. This

experimental study confirms the advantages of using free fatty acids,

which inhibit the rise in the level of blood triglycerides and thus their

storage in the adipose tissue.

PROBIOTICS The ARKOPHARMA Laboratories have completed their probiotics offer by launching a new line with
PROBIOTICS The ARKOPHARMA Laboratories have completed their probiotics offer by launching a new line with
PROBIOTICS
The ARKOPHARMA Laboratories have completed their probiotics offer
by launching a new line with 3 products: ARKOPROBIOTICS DEFENSE,
ARKOVISION is also formulated with numerous antioxidants that protect
the crystalline lens (B vitamins, including folic acid, vitamins PP and E)
and reduce the effects of ocular aging (Zinc, Copper, Manganese,
Selenium and Glutathione).
which are fresh and healthy dietary supplements that contain 5 to 50
billion active lactic ferments. This has made big news, thanks to the
exceptional and specially adapted refrigerated shipment containers used
to transport the products and thus ensuring the quality and integrity of
the probiotics.
For each product, the line offers several strains of probiotics that have
been specially chosen for their specific action on our immune system
and intestinal flora: ARKOPROBIOTICS JUNIOR DEFENSES and
ARKOPROBIOTICS ADULT DEFENSES, with a concentration of 5 to 10
billion probiotics + zinc and selenium, which come in small bottles as well
as
ARKOPROBIOTICS DEFENSES+ FOR ADULTS, with an exceptional dose
of
50 billion probiotics* and selenium, in the form of sachets.
OTHER NEW PRODUCTS
A genuinely
innovative
weight
loss
program by
ARKOPHARMA:
The ARKOPHARMA Laboratories have launched a new product to
SLIMEXCELL BODY CONTOURING ELIXIR. 25μg of chrome per day (i.e. 63%
of the recommended daily allowances RDA) stimulates fat and sugar

metabolism, thus preventing the storage of excess fat and reducing the desire for sweets. Toxin-eliminating fennel seed improves digestive comfort. Maté leaf burns fat and slows down digestion, thus eliminating sensations of hunger throughout the day. Grape Pomace, which is rich in polyphenols, drains and eliminates toxins from adipose cells as well as improves microcirculation. Pomegranate juice (330 mg of Pomegranate powder per day) is a powerful antioxidant.

Product advantages: a highly practical and innovative dosage form that can fit into even the smallest handbags: 30ml bottle with dropper; the product with the highest concentration in active ingredients on the market: 2 grams per day of active ingredients from titrated plant extracts (2.3% Polyphenols), at only 6 kcal per day, i.e. 3 tic-tacs

Thanks to the launch of ARKOVISION, the ARKOPHARMA Laboratories now offer a dietary supplement to help fight against damage done to the retina cells.

Although AMD (age-related macular degeneration) is the main cause of poor vision in older individuals, it can be prevented through micro- nutritional supplementation. AMD develops after the age of 50 and results in the progressive loss of central vision, leaving peripheral or lateral vision intact.

ARKOVISION is a dietary supplement that contains lutein and xanthophylls, which our body is unable to produce. They are natural pigments that are found in green leafy vegetables, certain fruit and corn. They are known for the important role they play in protecting the eyes

from the harmful effects of light (oxidation) by filtering blue light, which

is particularly harmful to the retina and crystalline lens and by

neutralizing free radicals, thanks to their antioxidant activity.

complete the Chondro-aid line: RESTRUCTURING CHONDRO-AID, which is mainly comprised of collagen (10 grams per sachet). Collagen is a fibrous structural protein that constitutes the protein of the skin, tendons, bones and especially the cartilage. It gives the different organs and tissue their strength and elastic properties.

Over time, the production of collagen in the body slows down, which affects the cartilage. This results in articular friction, which leads to pain.

This is why it is important to take large quantities of collagen as soon as the first signs of arthrosis or arthritis appear.

This product also contains ascorbic acid, which has a powerful effect on stimulating the collagen production process. In addition, it contains vitamin D3, which promotes bone recalcification, due to the more effective assimilation of calcium and hyaluronic acid that helps protect joints by increasing the viscosity of synovial fluid and adding greater elasticity to the cartilage.

4 % the share of net sales

devoted to research

1724

: the number of product licences

 

held by ARKOPHARMA

75 : the number of scientists working in Research and Development

 

The latest facilities in the Service of Health

Suitable industrial premises

One main site (Carros, 15 km from Nice), a site in Ireland opened in July 1998 and an another in Italy opened in march 2005, provide more than 105,000 m2 of industrial premises. The Group has modern, well-diversified equipment comprising about 90 machines or production lines making it possible to deal with most pharmaceutically manufactured galenic forms (powder and oil capsules, tablets, liquid and cosmetic forms). ARKOPHARMA’s know-how has enabled it to introduce innovations using an original manufacturing procedure applied to phytotherapy: freeze- grinding.

Freeze-grinding

This industrial technology was used for the first tine by ARKOPHARMA

for medicinal plants in 1985.

Freeze-grinding or grinding in liquid

Production, a few figures

Type of production

Volumes 2009

Plants used in manufacture

300 tonnes

Capsules, (Plant powder, mineral and vitamin, oil and antioxidant)

1.4 billion

Tablets

168 tonnes

Number of units packed

Containers (capsules and tablets)

21 million

Blisters and miscellaneous

23 million

Vials and bottles

2.7 million

Little vials

2.6 million

Ampoules

48 million

Bags

12.2 million

Tubes (tablets, liquids, homeopatics)

9.5 million

Tubes (tablets, liquids, homeopatics) 9.5 million nitrogen at-196oC preserves the whole of the plants’

nitrogen at-196oC preserves the whole of the plants’ active principles, intact. It provides a powder with optimum particle size and thus promotes the active principles’ bioavailability. It also improves productivity by making grinding easier. The production unit, operated by computer-aided production management software “SAP”, meets the firm’s growth requirements by providing a very large production capacity.

2009, industrial development

The industrial structure of the ARKOPHARMA Group is principally comprised of 3 production plants that are located in Carros (France), Waterford (Ireland) and Vintimille (Italy).

These 3 plants, which are completely complementary, provide the Group with industrial resources that are in full compliance with the strict pharmaceutical, food and cosmetic regulations. The corresponding production capacity is large enough to enable the plants to keep up with the Group’s projects and rate of development.

The industrial changes were based on the improved performance of our current installations.

In terms of performance, our production workshops have been organised using participatory working methods that aim at improving industrial

effectiveness. This has enabled us to increase productivity of certain

major processes (bottles, blisters, vials

This approach to continued improvement is one of the strong points behind our industrial management and will contribute in both the short and medium term to increase the ARKOPHARMA Group’s general performance.

)

1,4 billion the number of capsules packed by ARKOPHARMA in 2009
1,4 billion
the number of capsules packed by ARKOPHARMA
in 2009
the ARKOPHARMA Group’s general performance. ) 1,4 billion the number of capsules packed by ARKOPHARMA in
Dynamic marketing at everyone’s service The marketing teams endeavor to boost product sales on the
Dynamic marketing at everyone’s service The marketing teams endeavor to boost product sales on the
Dynamic marketing at everyone’s service
The marketing teams endeavor to boost product sales on the Pharmacy and Parapharmacy networks
● A network of medical representatives keeps gynecologists and general practitioners regularly informed about a
● A network of medical representatives keeps gynecologists and general
practitioners regularly informed about a selection of the Group’s
products that meet medical needs.
● A special division dedicated to Marketing and communication with:
- A Press Department, whose task is to publicize the Group’s
products in the Press, compile Press files and releases as well as
regularly visit the major editorial offices in Paris. In 2008, there were
over 800 write ups in both the professional and general public press,
thanks to press relations.
- A Direct Marketing Department, whose task is to boost

A team of Product Managers with dual training in Marketing and

Science, devises new products in cooperation with the Research & Development Department, boosts existing lines and promotes them through Press and TV campaigns and the provision of all promotional aids (counter and free-standing display units, showcards, maxi-boxes, booklets, brochures, etc.).

A team of sales promoters travels throughout France: its mission is to

support, train and guide the pharmacy teams in showcasing the product lines, advising and selling Group products. In 2008, these sales promoters assisted over 4,200 clients, via training programs (5,600 training sessions were given in pharmacies) and well- adapted merchandising advise.

communication operations targeting the ultimate consumers (Arkonews, informative newsletter

Part of the Global Marketing Department, the Multimedia Unit is in

charge of the Arkopharma Group’s web projects, with a focus on two main priorities: creating web sites and multimedia projects for all of the Group’s units and subsidiaries (web-design, web-publishing, web- development, server management, domain name management, e- learning and the creation of eBooks for the sales representatives) and web-marketing (web ranking, sponsored links and media buying campaigns, e-mailing campaign management, visitation analysis, competitive intelligence and follow-up on our e-reputation,…). And, since July 2009, Arkopharma has offered an e-Commerce solution to its pharmacy clients, who can now place their orders by Internet.

Graphic design and communication 2009: the year of standardized packaging Application of the European directive
Graphic design and communication 2009: the year of standardized packaging Application of the European directive
Graphic design and communication
2009: the year of standardized packaging
Application of the European directive on product licenses
Packaging for medicine has been changed, due to the 2008 European
directive. All of our products were updated prior to the directive
application date on May 7, 2009.
PRINTING HOUSE
IMPRIMEUR
The DTP team has added new coding and labeling, which must be placed
on both the packaging and the insert, such as the systematic use of
Braille to indicate the product name and dosage for the visually impaired
as well as the new generation CIP 13 bar codes.
Packaging, a joint effort between the Visual Design
& Communication Department and the plant team
Arkopharma
The Visual Design & Communication Department works hand in hand
with the teams at the manufacturing plant to standardize the
packaging.

The goal is to improve workflow fluidity, reduce the time required for the machine manufacturing phase and thus focus on creating high quality products

The Packaging Design and Methods divisions work together to resolve

their

technical

communication materials.

This collaboration is not new, simply the reflection of a new policy within the company.

manufacturing

constraints

and

create

their

the company. manufacturing constraints and create their In 2009, 1178 files were sent out to printers

In 2009, 1178 files were sent out to printers and magazines via FTP

The Visual Design & Communication Department has had a steady workload.

The 1178 files that were sent out included all of the different types of files that the Department manages: packaging components, POS advertising materials, press campaigns, the Arkonews magazine for the

general public, informative

- March was the most active month with 160 files completed

documents for pharmacists

- The most frequent packaging components were the boxes, with 400 new creations

- 25 files were sent out per graphic artist and per month in 2009.

The work is entirely done on-line: from the creation of the text that will be placed on the product (Marketing) to sending the file to the printer via FTP.

CDs are used less and less frequently and there are no more paper files used in the Visual Design & Communication Department: our company is committed to protecting the environment.

Development, sustainably

Respect of nature
Respect of nature
Development, sustainably Respect of nature True to its philosophy, ARKOPHARMA views its mission as a pharmaceutical

True to its philosophy, ARKOPHARMA views its

mission as a pharmaceutical company with the

greatest respect for Nature and basic ethical

principles.

Strict scientific rules and measures to ensure

quality help to produce natural, novel, safe and

effective medicines.

26

The environment’s respect:

Our Environment and Safety Commitment

As manufacturers of medicine, dietary products and cosmetics made from natural raw ingredients, the ARKOPHARMA Laboratories are committed to producing their entire product line, while ensuring optimal safety and health at work and protection of our environment.

Our policy in terms of safety and the environment includes risk control,

pollution prevention and managing our business activities in the spirit of

a socially responsible company with regards to our employees and nature.

Fully conscious of the responsibility that the pharmaceutical industry bears in terms of the outer world, our Safety and Environment commitment is a factor in internal progress and a trump card in our relations with our partners.

For Sustainable Production

Atmospheric waste control

ARKOPHARMA has developed industrial processes in which atmospheric waste is minimal and therefore controlled.

The atmospheric pollutants include dust and greenhouse gas.

is

to

systematically captured by efficient filtration installations.

Combustion gas emissions are also permanently controlled in our installations.

Dust

that

is

emitted

due

the

industrial

processes

Over the years, the reduction of pollutants in the air has become increasingly significant.

Protection of water resources

Control of water consumption is also an important part of this water resources protection policy. Water is of prime importance to our

We have

production, being one of our raw materials as well as a

noted a decrease in water consumption, which demonstrates, in part, a

In the framework of its strategic business plan, ARKOPHARMA continues

to be extremely involved in controlling our environmental impact, maintaining the safety conditions of our installations and equipment, promoting accident prevention and improving working conditions.

The Group’s Management ensures that these policies are implemented, and daily put into practice by all the firm’s departments. Here, they are backed by the Safety / Environment Department which contributes its expertise, with support from team members in the operational services and help from the CHSCT and the occupational physician.

Monthly committees were moreover established in every sector to answer closer in the continuous improvement.

The Environment: the factors involved

Protection of energy resources

Our energy policy is focused on rationalising energy consumption. Our technical teams are busy studying how to best optimise techniques for managing air conditioning stations, lighting, steam generation as well as stopping and restarting units.

rationalization of its use.

Aqueous waste control

The control of aqueous waste is part of the strategy to improveour environmental impact. Our self-monitoring program enables us to clearly determine our goals in terms of quantity and quality.

By regularly communicating these goals to our production personnel, we have been able to continually and increasingly raise their awareness.

Over the past several years, we have observed a decrease in our annual volume of aqueous waste.

The organizational measures and technical developments that we have implemented allow us to continue to significantly reduce the degree of pollution in the aqueous effluents discharged from the production sites.

to significantly reduce the degree of pollution in the aqueous effluents discharged from the production sites.

Efficient waste control

Managing waste disposal is a major challenge for our company. Over the past few years, we have placed emphasis on updating our waste management program by striving to reduce waste and recycle waste materials.

Given the fact that the cost of eliminating industrial waste is very expensive, more efficient waste control will allow us to bring together economic development and environmental concerns.

The waste production indicator for our activity is in constant decline, due to more efficient waste control.

The Safety/Environment Department is permanently striving to ensure that the waste sorting process is increasingly efficient. In 2009, a waste sorting program for paper was implemented on all of the Group’s sites.

Depending on the waste’s physicochemical nature, the Safety/Environment Department sends it to authorized waste recovery, recycling and disposal treatment and processing plants.

Safety / Occupational Health

We also have regulatory standards that are mainly taken from the

Environmental Code and in particular, the legislation on Classified

Installations for Environmental Protection (ICPE) as well as the Labor Code.

This is why our classified production sites are regularly and thoroughly

inspected by the public authorities.

This is not only due to the installations and equipment required for them

to operate, but also given the nature of certain products that are used

to produce our products.

The Safety/Environment Department is also in a position to rapidly

integrate regulatory changes, thanks to a monthly regulational watch.

We strive to take, whenever possible, a proactive approach in order to be

in full compliance with the legal obligations within the stated deadlines.

The increasing number of in-house audits on safety and the environment

has helped our employees become more involved and allowed us to reach

a more competitive level of conformity.

Investments in Environmental Protection and Safety

Occupational accidents

The prevention of occupational accidents and professional diseases is a priority in our policy of protecting Group staff members and partners.

It is preceded by risk studies prior to making investments and arrangements, in order to be able to integrate inherent safety principles in plant, equipment and processes as early as possible, right from the design stage.

All of these actions will help us continually reduce the number of work- related accidents. The results highlight a significant drop in the number of these accidents.

Industrial risk

Our installations are regularly monitored and maintained, and regulatory periodic checks are made.

Given our numerous storage and distribution activities as well as our processes that include flammable materials, fire is one of our major risks. High performance operational and organisational security systems ensure that our employees are permanently up to date on the measures to be taken for fire risk prevention and emergency responsiveness.

Regulatory factors

Given the diversity of our activities, we are subject to numerous regulations, which we use as a basis for the construction of our Environment & Safety measures.

As part of our continual improvement policy, ARKOPHARMA continues to

make investments to improve its installations, tools and production

processes. These significant efforts help endow us with a more efficient

working tool and include environmental protection dimensions as well as

the health and safety of people outside and inside the firm.

In 2009, investments were made due to new regulatory measures or, in

particular, to cover certain areas of safety in our installations. Efforts

were also made to control the potential impact on the environment and

use of energy resources.

Needless to say, this has to be compared with the operating budgets,

which include these important areas of Group management.

As we remain convinced that the success of our policy on safety and the

environment lies in each individual’s involvement and wiliness to take

responsibility, we also invest in training programs to enhance all of our

employees’ skills. In addition to the compulsory training programs, we

have developed a training plan that takes into consideration the

prevention improvement goals as well as the previously stated changes

in legislation. Moreover, practical summaries that describe good

practices for prevention are included in our information system, such as

safety data sheets for each work station, safety booklets per activity

sector as well as specific operating procedures.

In addition to this, responsible behavior audits in each sector will enable

us to regularly evaluate whether or not our employees have adopted this

responsible behavior.

Our social responsibility

Managing and Developing Skills

Constantly endeavouring to increase its level of competitiveness, thanks

to the continually improved skills of its personnel, the ARKOPHARMA

Laboratories are focusing on the development of expertise. Today, priority is placed on developing loyalty and motivating the company’s staff members in order to ensure the Group’s sustainability.

For the past several years, a management policy has been implemented

using the predictive management of jobs and skills approach. Tools such

as an ARKOPHARMA trades reference guide as well as job and description

definitions for each staff member are used.

The goals behind this process are:

- Better clarification of job limits, thanks to a comparison that measures the job requirements for a specific position and the capability and skills of the employees;

- Better clarification of the link between the various components

Dialogue: giving preference to nearness

Verbalisation meetings are held regularly in each Department. The aim is to enable staff members to express their feelings to their superiors concerning matters that are of importance to them. This contact, regarded as a special time for exchanging views, is a definite driving force in the development of the Group’s Human Resources policy.

Social dialogue also takes form in the quality of the relationships maintained between labour and management; several significant agreements are negotiated concerning various themes that boost the quality of the social context, in a common approach to the company’s success as well as the success of those who work in the company.

Protecting Human Health

In an industrial environment, ARKOPHARMA has chosen to monitor its

in the organisation in order to ensure a transversal dimension and improve communication;

- A more coherent remuneration system;

- Increased internal mobility thanks to an intranet that enables each staff member to apply for a job on line and thus be the prime mover in his/her advancement within the firm.

Social Protection: a Priority

Social protection has always been one of the ARKOPHARMA Group’s main concerns.

A new contract was negotiated in this aim with the managing

organisations enabling us to once again and in a socially positive manner develop this component of compensation.

The Group is constantly looking to improve its employees’ conditions concerning healthcare coverage.

For that purpose, the Group was equipped with services of a social worker who helps the employees in their personal problems.

Besides, the retirements, more and more numerous, and the modifications of the Law, motivated the Group to set up a service of personalized assistant.

staff to ensure their safety at work. Significant means (training, information, alerting, etc.) are devoted to human safety in order to reduce the incidence of accidents at work and their seriousness. Similarly, to mitigate the risk of occupational illness, ergonomists regularly work in close cooperation with employees, departmental heads and occupational medicine.

Expansion, internationally

ARKOPHARMA
ARKOPHARMA
Expansion, internationally ARKOPHARMA makes no secret of its powerful international ambitions, via the 8 subsidiaries. A

makes no secret of its powerful international

ambitions, via the 8 subsidiaries.

A worldwide presence in more than 60 countries

thanks to high-powered distribution contract

policy.

30

International horizons

In 2009, the ARKOPHARMA Group showed excellent results in its international business activities, despite the decrease in sales of its seasonal products, such as weight loss and sun care products

In a difficult international economic situation, which is due to the general decline of the world economy, the International Department’s global activity in 2009 has remained stable, on a like for like basis.

On the other hand, the Export Distributors structure (+7%) has shown excellent progress as they benefitted from the opening of new markets as well as the transfer of its subsidiaries’ activities to new distributors (i.e. England, Australia).

This winning strategy (closing non-strategic subsidiaries and focusing the subsidiaries’ business activities on Europe) has enabled us to make major savings and consolidate the largest distribution structures’ sales (Portugal, Germany and Saudi Arabia).

Moreover, and thanks to new European regulatory opportunities (phytotherapy remedies and dietary supplements), the Arkopharma

categories. This policy has finally proved to be successful and has allowed us to achieve 2 figure growth as compared to 2008 during the last four-

month period of 2009.
month period of 2009.

Group has been able to refocus its product mix/markets and increase product development in order to stay a cut ahead of its European competitors.

in order to stay a cut ahead of its European competitors. Product Mix All of these

Product Mix

All of these categories are showing buoyant growth and should reach their full potential in the years to come.

The international product portfolio not only focuses on the main OTC indications (Phytotherapy, articular pain, tonics) but also on the new therapeutic classes where self-medication is rapidly developing, such as treatments for recurring bladder infections using Cranberry extract and the prevention of winter colds and flu, with Echinacea, which stimulates the immune system.

Distributors

The Business Unit Export Distributor confirmed the strategy implemented by the ARKOPHARMA Group for its international development, outside of its subsidiaries, showing a global growth of 7% in sales to distributors as compared to 2008. The future looks very bright, due to the fact that our company shows overall growth in all regions and our active product portfolio is rapidly renewed. Moreover, the Latin American zone displayed buoyant growth with numerous countries showing a major expansion on the purely OTC pharmaceutical markets.

Phytotherapy has played a major role and thus enabled us to compensate for a lack of sales in the Weight loss and Menopause categories, as mature markets have become more difficult and highly competitive. Moreover, and given today’s unfavorable economic environment, there is a change in the behavior of consumers, who have made the decision to discontinue using certain intensive treatments / remedies.

Nonetheless, new product categories, such as hair loss treatments (FORCAPIL®) and chronic bladder infection treatments (CYS-CONTROL®) have continued to grow and consolidate their market share.

We have continued to deseasonalize our sales by reinforcing our position on the winter product lines: Royal jelly, cough and cold medicine, hair loss capsules as well as other products in the Vitamin and Mineral

jelly, cough and cold medicine, hair loss capsules as well as other products in the Vitamin

AKOPHARMA Spain

31

Outlook for 2010 The food supplement and plant-based product market (medicine or dietary supplements) in
Outlook for 2010 The food supplement and plant-based product market (medicine or dietary supplements) in
Outlook for 2010
The food supplement and plant-based product market (medicine or
dietary supplements) in Europe has become the Arkopharma Group’s
priority area of development on an international level, thus confirming
the company’s new focus on its core business: Phytotherapy, Plant-based
medicine and Specialties with a plant and vitamin-mineral base.
Lastly, we must highlight the fact that our Russian partner has stabilized
sales and successfully confronted the significant economic recession in
this region at the beginning of 2009.
New marketing operations have been planned for 2010 to relaunch our
Weight Loss, Phytotherapy and Tone/Vitality lines as well as promoting
different promotional operations in the various points of sale with a
view to developing long-term customer loyalty.
Priority will be placed on the Phytotherapy lines (ARKOCAPS and Plant
Ampoules) in order to develop our core business, which proves to be
highly solid and stable in relation to sales and the economic situation
As for the Distributors, 2010 has gotten off to a good start with
numerous new distribution agreements (Germany, Colombia, and Russia)
as well as the export of our PLANTE SYSTEM line. This development policy
should allow the Group to make a name for itself in the organic
cosmetics sector.

It is also important to note the imminent launch in numerous European countries of phytotherapeutic medicine for treating arthrosis, called HARPADOL®. It is a specialty that is made from cryoground Harpagophytum powder and is part of the ARKOCAPS line, which is the ARKOPHARMA Group’s Core Business line.

line, which is the ARKOPHARMA Group’s Core Business line. AKOPHARMA Belgium AKOPHARMA Netherlands AKOPHARMA Ireland
line, which is the ARKOPHARMA Group’s Core Business line. AKOPHARMA Belgium AKOPHARMA Netherlands AKOPHARMA Ireland

AKOPHARMA Belgium

the ARKOPHARMA Group’s Core Business line. AKOPHARMA Belgium AKOPHARMA Netherlands AKOPHARMA Ireland AKOPHARMA Italy 32

AKOPHARMA Netherlands

the ARKOPHARMA Group’s Core Business line. AKOPHARMA Belgium AKOPHARMA Netherlands AKOPHARMA Ireland AKOPHARMA Italy 32

AKOPHARMA Ireland

the ARKOPHARMA Group’s Core Business line. AKOPHARMA Belgium AKOPHARMA Netherlands AKOPHARMA Ireland AKOPHARMA Italy 32

AKOPHARMA Italy

Subsidiaries Distributors Specific sales and marketing follow-up in each country have again proved successful in
Subsidiaries
Distributors
Specific sales and marketing follow-up in each country
have
again proved successful in Europe.
Our international development except Europe has to
lean
on solid partnerships to penetrate into new
markets.
60 : the number of countries where ARKOPHARMA has a presence through its subsidiaries or
60 : the number of countries where ARKOPHARMA

60 : the number of countries where ARKOPHARMA

has a presence through its subsidiaries or distributors

60 : the number of countries where ARKOPHARMA has a presence through its subsidiaries or distributors
60 : the number of countries where ARKOPHARMA has a presence through its subsidiaries or distributors
60 : the number of countries where ARKOPHARMA has a presence through its subsidiaries or distributors
60 : the number of countries where ARKOPHARMA has a presence through its subsidiaries or distributors
60 : the number of countries where ARKOPHARMA has a presence through its subsidiaries or distributors
60 : the number of countries where ARKOPHARMA has a presence through its subsidiaries or distributors
60 : the number of countries where ARKOPHARMA has a presence through its subsidiaries or distributors
60 : the number of countries where ARKOPHARMA has a presence through its subsidiaries or distributors

Group Organisation Chart at 31 st December 2009

French subsidiaries

100%

FERRIER Laboratories Sarl.

Pharmaceutical Laboratory

100%

L H S S.A.

International subsidiaries
International subsidiaries

100%

ARKOCHIM ESPANA S.A.

Spain

100%

ARKOFARM Srl

Italy

100%

CIPRIANI Srl

Italy

100%

ARKOPHARMA UK Ltd.

United Kingdom

52%

ARKOPHARMA Nederland B.V.

Netherlands

96%

ARKOPHARMA BELUX

Belgium

100%

ARKOPHARMA Ireland

Ireland

100%

ARKO DIFFUSION SA

Switzerland

55%

ARKOPHARMA HELLAS

Greece

Administration, Management, Control

SUPERVISORY BOARD

Dr Max ROMBI

Chairman of the Supervisory Board

Monique ROMBI

Vice Chairman of the Supervisory Board

Bernard ROMBI

Member of the Supervisory Board

Janine ARON

Member of the Supervisory Board

MANAGEMENT BOARD

Philippe ROMBI

Chairman of the Management Board

Olivier ROMBI

Chief executive Officer

(Terms of office: june 2004 – june 2010)

(Terms of office: june 2004 – june 2010)

(Terms of office: june 2004 – june 2010)

(Terms of office: may 2009 – june 2015)

(Terms of office: june 2008 – november 2010)

(Terms of office: november 2004 – november 2010)

Bénédicte FOURNET

Chief executive Officer - Head Pharmacist

Brigitte ANDORRA

Member of the Management Board

FINANCE

Jean-Jacques ROBERT

Finance Director

STATUTORY AUDITORS CONTROL

CABINET TRINTIGNAC ET ASSOCIÉS

27, boulevard Général Vautrin 06000 CANNES

(Terms of office: november 2004 – november 2010)

(Terms of office: november 2004 – november 2010)

KPMG SA

Philippe LEVERT 80 route des lucioles 06560 SOPHIA ANTIPOLIS

(Terms of office: may 2009 – june 2015)

LABORATOIRES ARKOPHARMA

Limited Company with a Management Board and Supervisory Board with a capital of € 22 501 736 Registered Office: Zone industrielle de Carros - Premiere avenue 2709m – 06511 Carros (Alpes-Maritimes) - FRANCE Company Registration Number: Grasse B 307 378 489 Telephone: (33) 4 93 29 11 28 - Fax: (33) 4 93 29 11 62 Web Site: www.arkopharma.com – e-mail: info@arkopharma.com

Arkopharma group company addresses

FRANCE ARKOPHARMA Laboratories

LID de Carros-le-Broc

1re Avenue - 2709 m - BP 28

06511 CARROS CEDEX

Tél. : (33) 04 93 29 11 28 Fax : (33) 04 93 29 11 62 E-mail : info@arkopharma.com www.arkopharma.com

LHS

1re Avenue - 6008 m - BP 646

06511 CARROS CEDEX

Tél. : (33) 04 93 29 11 28 Fax : (33) 04 93 29 11 62 E-mail : adv-lhs@arkopharma.com

FERRIER Laboratories

SPAIN ARKOCHIM ESPANA SA

C/de Almatea, n°9

28045 MADRID

Tél. : (34) 91 527 15 12 Fax : (34) 91 527 99 91 E-mail : marketing@arkochim.es www.arkochim.es

GREECE ARKOPHARMA HELLAS

19002 PEANIA ATHENS

Tél. : (30) 210 66 83 000 Fax : (30) 210 66 83 250 E-mail : arriani@arriani.gr

ITALY

ARKOFARM Srl

Via Maneira n 17/c rosso - Frazione Bevera

IRELAND ARKOPHARMA IRELAND

Unit 507 Western Estate Waterford Industrial Estate, Ballynaneashagh WATERFORD Tél. : (353) 51 351 776 / 777 Fax : (353) 51 351 782

NETHERLANDS ARKOPHARMA NEDERLAND B.V.

Josephine Bakerstraat 43

Tél. : (31) 36 54 69 747 Fax : (31) 36 54 68 216 E-mail : arkoph47@XS4all.nl

SWITZERLAND

ARKO DIFFUSION

5D route des Jeunes

1211 GENEVE 26

LID de Carros-le-Broc

85 lavriou ave.

1311 GB ALMERE

LID de Carros-le-Broc

1re Avenue - 2709 m - BP 47

06511 CARROS CEDEX

Tél. : (33) 04 93 29 11 28 Fax : (33) 04 93 29 11 62 E-mail : adv-ferrier@arkopharma.com

BELGIUM ARKOPHARMA BELUX

Avenue Edison 13, Parc de la noire épine Zoning Nord 1300 WAVRE Tél. : (32) 2 10 233 600 Fax : (32) 2 10 233 610 E-mail : info@arkopharma.be

18039 VENTIMIGLIA IM

Tél. : (39) 0184 211 72 00 Fax : (39) 0184 211 74 00 E-mail : info@arkopharma-italia.com www.arkopharma.it

CIPRIANI Srl

Via Maneira n 17/c rosso - Frazione Bevera

18039 VENTIMIGLIA IM

Tél. : (39) 0184 211 72 00 Fax : (39) 0184 211 74 00 E-mail : cipriani@arkopharma.com www.ciprianilab.com

Tél. : (41) 22 300 1381 Fax : (41) 22 300 1396 E-mail : info@arkodiffusion.ch

B.P. 28 - 06511 Carros cedex - France - Tel. : + 33 (0) 4

B.P. 28 - 06511 Carros cedex - France - Tel. : + 33 (0) 4 93 29 11 28 - Fax : + 33 (0) 4 93 29 11 62 Web Site: www.arkopharma.com – e-mail: info@arkopharma.com