ORDER PATHOGNOMICS

A Arachnodactyly is pathognomic for Marfan's

Autosplenectomy is pathognomic for sickle cell anemia

Albumino-Cytologic Dissociation is pathognomic for Guillain-Barre

(markedly increased protein in CSF with only modest increase in cell count)

AFP in amniotic fluid or mother's serum is pathognomic for Spina Bifida&

Anencephaly

B Babinski is pathognomic for UMN lesion

Bence Jones Protein is pathognomic for multiple myeloma free light chains
(either kappa or lambda) & Waldenstrom's macroglobinemia

Blue Bloater is pathognomic for Chronic Bronchitis

Basophilic Stippling of RBCs is pathognomic for lead poisoning

C Cheyne-Stokes Breathing is pathognomic for cerebral lesion

Cold Agglutinins is pathognomic for Mycoplasma pneumoniae & infectious

mononucleosis

Crescents In Bowman's Capsule is pathognomic for rapidly progressive

(crescentic glomerulonephritis)

Chancre is pathognomic for primary Syphilis

Chancroid is pathognomic for Haemophilus ducreyi

Curschmann's Spirals is pathognomic for bronchial asthma

Condyloma Lata is pathognomic for secondary Syphilis

Currant-Jelly Sputum is pathognomic for Klebsiella

Cardiomegaly with Apical Atrophy is pathognomic for Chagas' Disease

D Depigmentation Of Substantia Nigra is pathognomic for Parkinson's

E Ectopia Lentis is pathognomic for Marfan's

 Erythema Chronicum Migrans is pathognomic for Lyme Disease

Eburnation is pathognomic for osteoarthritis (polished ivory-like appearance

of bone)

F Fatty Liver is pathognomic for Alcoholism and relatively normal with age and
obesity

G Ghon Focus / Complex is pathognomic for Tuberculosis (primary &

secondary respectively)

Gower's Maneuver is pathognomic for Duchenne's MD use of arms to stand

H Hemorrhagic Urticaria is pathognomic for Henoch-Schonlein

Hypochromic Microcytic RBCs is pathognomic for iron-deficiency anemia

Hypersegmented PMNs is pathognomic for Megaloblastic anemia

J Joint Mice is pathognomic for osteoarthritis (fractured osteophytes)

K Kaussmaul Breathing is pathognomic for acidosis

L Lumpy-Bumpy IF Glomeruli is pathognomic for poststreptococcal

glomerulonephritis

M Myxedema is pathognomic for hypothyroidism

Monoclonal Antibody Spike is pathognomic for multiple myeloma this is

called the M protein (usually IgG or IgA) & MGUS

N Notching of Ribs is pathognomic for Coarctation of Aorta

 Non-pitting Edema is pathognomic for Myxedema & Anthrax Toxin

Neurofibrillary Tangles is pathognomic for Alzheimer's

Nutmeg Liver is pathognomic for CHF

P Painless Jaundice is pathognomic for pancreatic CA (head)

Pannus is pathognomic for rheumatoid arthritis

Pautrier's Microabscesses is pathognomic for mycosis fungoides (cutaneous

T-cell lymphoma)

Pseudohypertrophy is pathognomic for Duchenne muscular dystrophy

Pink Puffer is pathognomic for Emphysema Centroacinar smoking Panacinar

- a1-antitrypsin deficiency

Philadelphia Chromosome is pathognomic for CML & ALL=t (9,22)

Podagra is pathognomic for gout (MP joint of hallux)

Punched-Out Bone Lesions is pathognomic for multiple myeloma

R Reid Index Increased is pathognomic for chronic bronchitis

Rouleaux Formation is pathognomic for multiple myeloma RBC's stacked as

poker chips

Rash on Palms & Soles is pathognomic for secondary Syphilis & RMSF

Red Morning Urine is pathognomic for paroxysmal nocturnal

hemoglobinuria

S Spike & Dome Glomeruli is pathognomic for membranous

glomerulonephritis

Smith Antigen is pathognomic for SLE (also anti-dsDNA)

 Soap Bubble on X-Ray is pathognomic for giant cell tumor of bone

Simian Crease is pathognomic for Down's

S4 Heart Sound is pathognomic for Pulmonary Stenosis & Pulmonary HTN

S3 Heart Sound is pathognomic for L®R Shunt (VSD PDA) & Mitral Regurg
& LV Failure

T Tendinous Xanthomas is pathognomic for Familial Hypercholesterolemia

Tram-Track Glomeruli is pathognomic for membranoproliferative

glomerulonephritis

Thyroidization of Kidney is pathognomic for chronic pyelonephritis

Tophi is pathognomic for gout

W Wire Loop Glomeruli is pathognomic for lupus nephropathy type IV