DR.

SONAL MALHOTRA
House #863, Sector 17 * Faridabad, Haryana, India 121002
91-999-133-75-87 * 91-981-858-4229. sonalmalhotra07@gmail.com
BIOTECHNOLOGY: ACADEMIC or INDUSTRIAL SCIENTIST * PROFESSOR
Highly experienced science/biotechnology professional with nearly 20 years of ha
nds-on research and undergraduate and graduate teaching experience, including 15
years in the U.S. as a researcher and professor for multiple educational instit
utions. Instrumental in creating global awareness for students by incorporating
U.S.-based ideas and learning. Combines expertise in specific subjects, includin
g genomics and proteomics tools and disulfide isomerases, with strong skills in
key areas, from staff supervision and project management to presentations and tr
aining.

College-level Course Design & Instruction * Student Advisement * Staff Training

& Management
Laboratory Equipment Procurement * Microbiology Research & Analysis * Project Ma
nagement
Presentations & Seminars * Hindi, Punjabi, Urdu & English Fluency

PROFESSIONAL EXPERIENCE
MAHARISHI MARKHANDESHWAR UNIVERSITY, Mullana, Ambala, India * 2008-Present
SINGHANIA UNIVERSITY, Bari, Rajastan, India * 2008-July 2009
Professor; Associate Professor/Consultant
Maharishi Markhandeshwar: Develop, plan, and teach 2 courses - Fundamentals of M
icrobiology and Applied Microbiology (undergraduate) and Master-level Fermentat
ion Technology course for one of India's largest private universities. Supervise
4 faculty members and contribute to recruitment of new staff and overall depart
ment management. Author proposals for University funding of projects.
Singhania: Prepared and taught courses to more than 50 students in Biotech, Micr
obiology, Bioinformatics Principles, Genomics, and Proteomics for rural universi
ty. Provided hands-on counseling and assistance with job searches and interview
strategies.
Major Highlights
Mahariski Markhandeshwar
* Designed and facilitated course of study for new Biotechnology program (Engine
ering discipline) in the Bachelor's of Technology (BTECH) program.
* Played key role in recruitment of students - provided preadmission counseling
and guidance regarding course benefits - brought in over 100 students to BTECH p
rogram, and more than 25 to the MTECH program (Masters).
* Personally designed new teaching laboratory - gathered information from both o
nline and professional sources, including consultations with eminent Indian scie
ntists in both Industry and Academia).
Singhania
* Successfully conducted three 6-month courses and supervised research projects
for students.
* Invited to guide several Ph.D. thesis studies.

J. SARGAENT REYNOLDS COMMUNITY COLLEGE, Richmond, Virginia * 2006-2007

Community college offering 2-year degree programs, as well as certificate progra
ms.
Adjunct Professor of Biology
Delivered BIOL 101 and BIOL 102 courses.
Major Highlights
* Earned accolades and appreciation from students by proactively engaging them i
n coursework and potential improvements to class administration.
* Expertly guided Courses in Ecology and conducted field projects with students.

DR. SONAL MALHOTRA * Page 2 * sonalmalhotra07@gmail.com

UNIVERSITY OF VIRGINIA, Charlottesville, Virginia, WI * 2004-2006

Public research university with 13K+ undergraduate students and 6K+ graduate stu
dents.
Research Associate
Supervised 2 students and 1 technician in genomic research focused on Identifica
tion and Characterization of BHV (broad host virulence) locus in Staphylococcus
aureus using the Caenorhabditis elegans infection model.
Major Highlights
* Determined individual and cumulative contributions of members of the BHV locus
to virulence and biofilm formation using the C. elegans infection model by gene
rating single and double deletion knock outs of members of this locus.
* Worked with biothreat agent Franscicella tularensis.

CAREER NOTE: Previous history includes role as Junior Scientist for HMGENEInc.

POST-GRADUATE RESEARCH EXPERIENCE

UNIVERSITY OF MASSACHUSETTS, Worcester, Massachusetts * 1998-2000
Post-doctoral Associate
Conducted research on identification of contributions to Haemophilus influenzae
pathogenesis by the dsbA ortholog por (Periplasmic oxidoreductase). Subsequent s
tudies on the periplasmic fractions using single dimension gel sub-proteomics an
d mass spectrophotometric analysis revealed ribH as a downstream target of por.
VIRGINIA POLYTECHNIC AND STATE UNIVERSITY, Blacksburg, Virginia * 2001-2003
Post-doctoral Associate
Conducted research to examine the nodulation process in the Microsymbiont Sinorh
izobium melliloti and its host Medicago truncatula. Utilized advanced genomics a
nd proteomics tools in set-up of the laboratory.

GRADUATE RESEARCH EXPERIENCE

UNIVERSITY OF TENNESSEE, Memphis, Tennessee * 1992-2000
1996-2000 - Mentor: Prof. Dennis E. Ohman
Employed Proteomic and Genomic analysis to identify transcriptional and proteomi
c changes upon mucoid conversion in Pseudomonas aeruginosa strain PAO1. Analysis
 identified bona-fide targets of AlgT (Sigma-22, an E. Coli Sigma E ortholog) th
e dsbA gene and also a novel 15 kDa protein with unknown function. Additionally,
identified targets-AruC (an arginine biosynthesis enzyme) in particular-that we
re repressed by AlgT. Subsequent characterization of DsbA showed that it was not
required for alginate biosynthesis, suggesting that the AlgT regulon encompasse
s a large set of genes besides those involved in Alginate biosynthesis. Analysis
has set the path for further genomic proteomic and systemic characterization of
regulons in P. aeruginosa.
1992-1996 - Mentor: Dr. Lorraine Albritton
Conducted research focused on characterizing the receptor domain for the murine
ecotropic virus receptor in mATRC1. Used homology scanning to identify residues
that may be critical for receptor function. Subsequently, determined that alanin
e scanning mutagenesis and biochemical substitutions would help identify and del
ineate the biochemical role of these residues that were critical for function.

EDUCATION
Doctor of Philosophy in Microbiology, University of Tennessee, Memphis, Tennesse
e
Degree in Zoology, Delhi University, Delhi, India
**Complete list of Training, Publications, Presentations, and Speaking Engagemen
ts available upon request
DR. SONAL MALHOTRA
House #863, Sector 17 * Faridabad, Haryana, India 121002
91-999-133-75-87 * sonalmalhotra07@gmail.com
TRAINING
Graduate-level course in Bioinformatics - Virginia Polytechnic and State Univers
ity
Certificate course in open distance learning - Indira Gandhi National Open Unive
rsity (IGNOU)
I have a certificate in Leadership training - Maharishi Markhandeshwar Universit
y

MEMBERSHIPS
American Society of Microbiology Members (since 1998)

PUBLICATIONS
* Ajay Kumar and Sonal Malhotra. A Simple Method For Introducing -SH Group at 5'
OH Terminus of Oligonucleotides. Nucleosides & Nucleotides 1992 11(5): 1003 -
1007. Copyright 1992, Marcel Dekker, Inc.
* Malhotra, S., A. G. Scott, T. Zavorotinskaya, and L. M. Albritton. Analysis of
the Murine Ecotropic Leukemia Virus Receptor Reveals a Common Biochemical Deter
minant on Diverse Cell Surface that is Essential to Retrovirus Entry. Journal of
Virology, Jan 1996; 70 (1): 321-6.
* Ohman, D.E., S. Malhotra, S. Jain, K. Mathee, and L. A. Silo-Suh. Alginate bio
synthesis in Pseudomonas aeruginosa: a stress response. Clinical Microbiology 19
99; 5:5S11-13.
* Malhotra, S., L. A. Silo-Suh and D. E. Ohman. A Proteome Analysis of the Effec
t of Mucoid Conversion on Global Protein Expression in Pseudomonas aeruginosa St
rain PAO1 Shows Induction of Disulfide Bond Isomerase, DsbA. J Bacteriol. Dec 20
00; 182(24): 6999-7006.
* 5) Malhotra, S, S. Suh and D. E. Ohman. A Proteome Analysis on Global Protein
Expression in Pseudomonas aeruginosa Cystic Fibrosis Isolate FRD1, Shows Induct
ion of a 15 kDa Protein that is Homologous to Escherichia coli Protein YgaU. (I
n preparation).
* 6) Sonal Malhotra, Qiang Chen, Nicole J. Mcmaster and Bruno W. S. Sobral. A Th
ioredoxin Like Protein (tlpA) Ortholog in Sinorhizobium meliloti is Critical For
the Nodulation Process (In preparation).
* Sonal Malhotra, Brian J. Akerley and Dennis E. Ohman: An examination of Disulf
ide Isomerase function in two Distinct Bacterial Systems Reveals Common Pathways
of Action that may Control Bacterial Virulence. CETAS-2009 (Changing Environmen
tal Trends and Sustainable Development) International Conference in Hissar India
. February 9-11, 2009 Proceedings CETAS Page 344.
* Sonal Malhotra: Examination of a Genetic Basis for Leadership traits using Man
ic Depressive Illness as a Model. 16th EDIC National Conference on New Initiativ
es in Entrepreneurship and Industry-Institute Interface. September 16-17th 2009.
National Institute of Technical Teachers Training and Research, Chandigarh, Ind
ia.
* Sonal Malhotra and Ramesh Chand. Identification of Potential DNA sequences in
Pseudomonas aeruginosa and other Food borne pathogens that could serve as poten
tial as diagnostic markers. Accepted for Publication in Proceedings of National
Conference on Hospitality Industry in India - Developments & Challenges: Nov. 6-
7, 2009.
* Sonal Malhotra. New and Alternate ways to enhance efficient oil production fro
m Algae and potentially Microorganisms. Accepted for Publication and Presentati
on at the NITTTR Conference on Cleaner Production Technologies. November 16th -N
ovember 17th 2009.
* Sonal Malhotra. Efficient Waste management of Liquid Oil from University and H
ospital Cafeterias-A systematic Analysis. Accepted for Publication and Presentat
ion at the NITTTR Conference on Cleaner Production Technologies. November 16th -
November 17th 2009.

DR. SONAL MALHOTRA * Page 2 * sonalmalhotra07@gmail.com

POSTER AND ABSTRACT PRESENTATIONS

* Malhotra, S., A. Scott and L. M. Albritton. Biochemical Contribution of an Ess
ential Tyrosine Residue in the MulV-E Receptor-SU Protein Interaction. Retroviru
s Meeting at Cold Spring Harbor May 24-May 29, 1994.
* Malhotra, S., and D. E. Ohman. Use of a 2-Dimensional Gel Analysis Reveals Pro
teins in Pseudomonas aeruginosa whose Respective Genes are Regulated by the Alte
rnate Sigma Factor AlgT. Annual American Society for Microbiology Meeting. Chica
go IL May 1999.
* Malhotra S, Nicole J. McMaster, Eric Nordberg and Bruno W. S. Sobral. A Global
Examination of the Nodulation Process in the Model Microsymbiont, Sinorhizobium
meliloti and its host Medicago truncatula. Poster displayed at Congressional Me
eting, Virginia Tech- Northern VA Campus, May 2002.
* Sonal Malhotra, Qiang Chen, Nicole J. Mcmaster and Bruno W. S. Sobral. A Thior
edoxin Like Protein (tlpA) Ortholog in Sinorhizobium meliloti is Critical For th
e Nodulation Process. Abstract presented at Annual American Society for Microbio
logy Meeting, New Orleans, LA May 2004.
* Sonal Malhotra and Costi D. Sifri. Comparison of the Disulfide Isomerase dsbA
genes Between Gram Positive and Gram Negative Bacteria Reveals Distinct Sequence
Divergence in Conserved Domains. Poster presented at the Annual Research Day ce
lebration. Dept. of Internal Medicine. University of Virginia at Charlottesville
. May 3, 2005.
* Torres-Zapata, Irimar, UPR-MAYAGUEZ; Malhotra Sonal, Division of Infectious Di
seases & International Health University of Virginia Health System; Sifri Costi
D.,Division of Infectious Diseases & International Health University of Virginia
Health System. Caenorhabditis Elegans: A Novel Host For Staphylococcus aureus P
athogenesis. 41st ACS Junior Technical Meeting & 26th Puerto Rico Interdisciplin
ary Scientific Meeting (PRISM), University of Puerto Rico at Cayey 2006.

INVITED SPEAKING ENGAGEMENTS

* Research presentation to Prof. Sharon Long's Research Lab, Dept. of Biological
Sciences, Stanford University, Stanford CA. May 2002. Developed partnership wit
h the Long lab group. We obtained several plasmid constructs to establish a mol
ecular genetic lab at Virginia Tech to study the microsymbiont Sinorhizobium Mel
iloti.
* Lecture at Rocky Mountain laboratories, National Institute of Health, 903, Sou
th Street, Hamilton MT 59840. December 12, 2004. Title: The biological role of D
isulfide Isomerases Revealed by Genomic Analysis. Guest of Dr. Olivia Steele Mor
timer.
* Seminar presentation at Plum Island Disease Center, United States Department o
f Agriculture. Foreign Animal Disease Research Unit. USDA, ARS, PIADC. Title: I
mpact of bioinformatics and genomic biology on addressing keys biology problems-
A case in point Disulfide Isomerases Examined by Genomic Analysis. Primary focu
s was examination of various methods to develop genomic and bioinformatics tools
to study FMV virus and other biological systems at Plum Island. Guest of Dr. Lo
uis Rodriguez.
* Discussion forum on Bird Flu and its socio-economic impact on The Asian Contin
ent. June 22, 2006. Guest of Brigadier Khanna and Mr. M. M. Malhotra, members of
Thinker's Forum, 863, Sector 17, Faridabad, Haryana. India 121002.
* Seminar presentation at School of Biotechnology, Jawaharlal Nehru University,
New Delhi, India. March 24th, 2008. Seminar topic: An Examination of the AlgT r
egulon in Pseudomonas aeruginosa, using genomic and proteomic strategies.
* Training seminar on Molecular Biology, to Lecturers and Teachers of local Gove
rnment Colleges. Academic Staff College, Jawaharlal Nehru University, New Delhi,
India. August 6th 2009.