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Homeopathy: coined in German from Greek hómoios- ὅμοιος- "like-" + páthos πάθος "suffering"
Homeopathy's efficacy beyond the placebo effect is unsupported by the collective weight of
scientific and clinical evidence.[2][3][12][13][14] While some individual studies have positive results,
systematic reviews of published trials fail to conclusively demonstrate efficacy.[15][16][17][18][19]
Furthermore, higher quality trials tend to report results that are less positive,[17][20] and most
positive studies have not been replicated or show methodological problems that prevent them
from being considered unambiguous evidence of homeopathy's efficacy.[2][13][21][22] A 2010 inquiry
into the evidence base for homeopathy conducted by the United Kingdom's House of Commons
Science and Technology Committee concluded that homeopathy is no more effective than
placebo.[3]
Depending on the dilution, homeopathic remedies may not contain any pharmacologically active
molecules,[23] and for such remedies to have pharmacological effect would violate fundamental
principles of science.[14][24] Modern homeopaths have proposed that water has a memory that
allows homeopathic preparations to work without any of the original substance; however, there
are no verified observations nor scientifically plausible physical mechanisms for such a
phenomenon.[24][25] The lack of convincing scientific evidence supporting homeopathy's
efficacy[26] and its use of remedies lacking active ingredients have caused homeopathy to be
described as pseudoscience, quackery,[27][28][29][30][31] and a "cruel deception".[32]
The regulation and prevalence of homeopathy is highly variable from country to country. There
are no specific legal regulations concerning its use in some countries, while in others, licenses or
degrees in conventional medicine from accredited universities are required. In several countries,
homeopathy is covered by the national insurance coverage to different extents, while in some it
is fully integrated into the national health care system. In many countries, the laws that govern
the regulation and testing of conventional drugs do not apply to homeopathic remedies.[33]
Contents
[hide]
• 1 General philosophy
○ 1.1 Hahnemann's "Law of similars"
○ 1.2 Miasms and disease
• 2 Homeopathic remedies
○ 2.1 Preparation
○ 2.2 Dilutions
2.2.1 Dilution debate
○ 2.3 Provings
○ 2.4 Repertory
○ 2.5 Homeopathic pills
○ 2.6 List of ingredients
• 3 Related practices
○ 3.1 Isopathy
○ 3.2 Flower remedies
○ 3.3 Veterinary use
• 4 Medical and scientific analysis
○ 4.1 High dilutions
○ 4.2 Effectiveness
○ 4.3 Meta-analyses
4.3.1 Scientific explanations of effects
○ 4.4 Effects in other biological systems
○ 4.5 Methodological and publication issues
○ 4.6 Ethics and safety
• 5 Regulation and prevalence
• 6 History
○ 6.1 Historical context
○ 6.2 Hahnemann's concept
○ 6.3 19th century: rise to popularity and early criticism
○ 6.4 Revival in the late 20th century
• 7 See also
• 8 References
• 9 Footnotes
• 10 External links
○ 10.1 Videos
○ 10.2 Associations and regulatory bodies
General philosophy
A homeopathic remedy prepared from marsh Labrador tea. The "15C" dilution shown here
contains no molecules of the original herb.
Homeopathy is a vitalist philosophy which interprets diseases and sickness as caused by
disturbances in a hypothetical vital force or life force. It sees these disturbances as manifesting
themselves as unique symptoms. Homeopathy maintains that the vital force has the ability to
react and adapt to internal and external causes, which homeopaths refer to as the law of
susceptibility. The law of susceptibility implies that a negative state of mind can attract
hypothetical disease entities called miasms to invade the body and produce symptoms of
diseases.[34] However, Hahnemann rejected the notion of a disease as a separate thing or invading
entity and insisted that it was always part of the "living whole".[35] Hahnemann proposed
homeopathy in reaction to the state of traditional western medicine at that time, which often was
brutal and more harmful than helpful.[citation needed]
Hahnemann's "Law of similars"
Hahnemann observed from his experiments with cinchona bark, used as a treatment for malaria,
that the effects he experienced from ingesting the bark were similar to the symptoms of malaria.
He therefore decided that cure proceeds through similarity, and that treatments must be able to
produce symptoms in healthy individuals similar to those of the disease being treated.[36] Through
further experiments with other substances, Hahnemann conceived of the law of similars,
otherwise known as "let like be cured by like" (Latin: similia similibus curentur)[37][38] as a
fundamental healing principle. He believed that by using drugs to induce symptoms, the artificial
symptoms would stimulate the vital force, causing it to neutralise and expel the original disease
and that this artificial disturbance would naturally subside when the dosing ceased.[36] It is based
on the belief that a substance that in large doses will produce symptoms of a specific disease
will, in extremely small doses, cure it.
Hahnemann's law of similars is an "ipse dixit" "axiom",[5] in other words an unproven assertion
made by Hahnemann, and not a true law of nature.[4]
Miasms and disease
In 1828, Hahnemann introduced the concept of miasms; underlying causes for many known
diseases.[39] A miasm is often defined by homeopaths as an imputed "peculiar morbid
derangement of [the] vital force".[40] Hahnemann associated each miasm with specific diseases,
with each miasm seen as the root cause of several diseases. According to Hahnemann, initial
exposure to miasms causes local symptoms, such as skin or venereal diseases, but if these
symptoms are suppressed by medication, the cause goes deeper and begins to manifest itself as
diseases of the internal organs.[41] Homeopathy maintains that treating diseases by directly
opposing their symptoms, as is sometimes done in conventional medicine, is ineffective because
all "disease can generally be traced to some latent, deep-seated, underlying chronic, or inherited
tendency".[42] The underlying imputed miasm still remains, and deep-seated ailments can only be
corrected by removing the deeper disturbance of the vital force.[43]
Hahnemann's miasm theory remains disputed and controversial within homeopathy even in
modern times. In 1978, Anthony Campbell, then a consultant physician at The Royal London
Homeopathic Hospital, criticised statements by George Vithoulkas claiming that syphilis, when
treated with antibiotics, would develop into secondary and tertiary syphilis with involvement of
the central nervous system.[11] This conflicts with scientific studies, which indicate that penicillin
treatment produces a complete cure of syphilis in more than 90% of cases.[44] Campbell described
this as "a thoroughly irresponsible statement which could mislead an unfortunate layman into
refusing orthodox treatment".[11]
Originally Hahnemann presented only three miasms, of which the most important was "psora"
(Greek for itch), described as being related to any itching diseases of the skin, supposed to be
derived from suppressed scabies, and claimed to be the foundation of many further disease
conditions. Hahnemann believed psora to be the cause of such diseases as epilepsy, cancer,
jaundice, deafness, and cataracts.[39] Since Hahnemann's time, other miasms have been proposed,
some replacing one or more of psora's proposed functions, including tubercular miasms and
cancer miasms.[41]
The theory of miasms has been criticized as an explanation developed by Hahnemann to preserve
the system of homeopathy in the face of treatment failures, and for being inadequate to cover the
many hundreds of sorts of diseases, as well as for failing to explain disease predispositions as
well as genetics, environmental factors and the unique disease history of each patient.[45]
Homeopathic remedies
High dilutions
The extremely high dilutions in homeopathy have been a main point of criticism. Homeopathic
remedies are usually diluted to the point where there are no molecules from the original solution
left in a dose of the final remedy.[99] Homeopaths believe that the methodical dilution of a
substance, beginning with a 10% or lower solution and working downwards, with shaking after
each dilution, produces a therapeutically active remedy, in contrast to therapeutically inert water.
Since even the longest-lived noncovalent structures in liquid water at room temperature are only
stable for a few picoseconds,[106] critics have concluded that any effect that might have been
present from the original substance can no longer exist.[107] No evidence of stable clusters of
water molecules was found when homeopathic remedies were studied using NMR.[108]
Furthermore, since water will have been in contact with millions of different substances
throughout its history, critics point out that water is therefore an extreme dilution of almost any
conceivable substance. By drinking water one would, according to this interpretation, receive
treatment for every imaginable condition.[109]
Practitioners of homeopathy contend that higher dilutions produce stronger medicinal effects.
This idea is inconsistent with the observed dose-response relationships of conventional drugs,
where the effects are dependent on the concentration of the active ingredient in the body.[100] This
dose-response relationship has been confirmed in multitudinous experiments on organisms as
diverse as nematodes,[110] rats,[111] and humans.[112]
Physicist Robert L. Park, former executive director of the American Physical Society, has noted
that
Park has also noted that "to expect to get even one molecule of the 'medicinal' substance
allegedly present in 30X pills, it would be necessary to take some two billion of them, which
would total about a thousand tons of lactose plus whatever impurities the lactose contained".
The laws of chemistry state that there is a limit to the dilution that can be made without losing
the original substance altogether.[23] This limit, which is related to Avogadro's number, is roughly
equal to homeopathic potencies of 12C or 24X (1 part in 1024).[68][101][113]
Scientific tests run by both the BBC's Horizon and ABC's 20/20 programs were unable to
differentiate homeopathic dilutions from water, even when using tests suggested by homeopaths
themselves.[56][114]
Effectiveness
In 2002, a review of systematic reviews found that higher-quality trials tended to have less
positive results, to the point that those results were clinically irrelevant. Also, when taking
collectively all the systematic reviews, there was no convincing evidence that any homeopathic
remedy had better effects than placebo, and current evidence did not allow to recommend its
usage in clinical treatment.[2]
In 2005, a systematic review of the representation of homeopathy in the medical literature
suggested that mainstream journals had a publication bias against clinical trials of homeopathy
that showed positive results, and the opposite was the case for complementary and alternative
medicine journals. The authors suggested that this could be due to an involuntary bias, or
otherwise a submission bias, in which positive trials tend to be sent to CAM journals and
negatives ones to mainstream journals.[20] Reviews in all journals approached the subject in an
apparently impartial manner, though most of the reviews published in CAM journals made no
mention of the plausibility of homeopathy, whereas 9 out of 10 reviews in mainstream journals
mentioned a lack of plausibility of homeopathy in the introduction.[20]
In 2005, The Lancet medical journal published a meta-analysis of 110 placebo-controlled
homeopathy trials and 110 matched medical trials based upon the Swiss government's Program
for Evaluating Complementary Medicine, or PEK. The study concluded that its findings were
compatible with the notion that the clinical effects of homeopathy are nothing more than placebo
effects.[14]
A 2006 meta-analysis of six trials evaluating homeopathic treatments to reduce cancer therapy
side effects following radiotherapy and chemotherapy found "encouraging but not convincing"
evidence in support of homeopathic treatment. Their analysis concluded that there was
"insufficient evidence to support clinical efficacy of homeopathic therapy in cancer care".[120]
A 2007 systematic review of homeopathy for children and adolescents found that the evidence
for attention-deficit hyperactivity disorder and childhood diarrhea was mixed. No difference
from placebo was found for adenoid vegetation, asthma, or upper respiratory tract infection.
Evidence was not sufficient to recommend any therapeutic or preventative intervention.[13]
The Cochrane Library found insufficient clinical evidence to evaluate the efficacy of
homeopathic treatments for asthma[121] dementia,[122] or for the use of homeopathy in induction of
labor.[123] Other researchers found no evidence that homeopathy is beneficial for osteoarthritis,[124]
migraines[125] or delayed-onset muscle soreness.[90]
Health organisations such as the UK's National Health Service,[126] the American Medical
Association,[127] and the FASEB[107] have issued statements of their conclusion that there is no
convincing scientific evidence to support the use of homeopathic treatments in medicine.
Clinical studies of the medical efficacy of homeopathy have been criticised by some homeopaths
as being irrelevant because they do not test "classical homeopathy".[128] There have, however,
been a number of clinical trials that have tested individualized homeopathy. A 1998 review[129]
found 32 trials that met their inclusion criteria, 19 of which were placebo-controlled and
provided enough data for meta-analysis. These 19 studies showed a pooled odds ratio of 1.17 to
2.23 in favor of individualized homeopathy over the placebo, but no difference was seen when
the analysis was restricted to the methodologically best trials. The authors concluded "that the
results of the available randomized trials suggest that individualized homeopathy has an effect
over placebo. The evidence, however, is not convincing because of methodological shortcomings
and inconsistencies." Jay Shelton, author of a book on homeopathy, has stated that the claim
assumes without evidence that classical, individualized homeopathy works better than
nonclassical variations.[130]
Jack Killen, acting deputy director of the National Center for Complementary and Alternative
Medicine, says homeopathy "goes beyond current understanding of chemistry and physics." He
adds: "There is, to my knowledge, no condition for which homeopathy has been proven to be an
effective treatment."[26]
Scientific explanations of effects
Mainstream science offers a variety of explanations for how homeopathy, if the preparations
themselves are ineffective, may appear to cure diseases or alleviate symptoms:[131]
• Unassisted natural healing — time and the body's ability to heal without assistance can
eliminate many diseases of their own accord
• Unrecognized treatments — an unrelated food, exercise, environmental agent or
treatment for a different ailment, may have occurred
• Regression toward the mean — since many diseases or conditions are cyclical, symptoms
vary over time and patients tend to seek care when discomfort is greatest, they may feel
better anyway but because the timing of the visit to the homeopath they attribute
improvement to the remedy taken
• Non-homeopathic treatment — patients may also receive non-homeopathic care
simultaneous with homeopathic treatment, and this is responsible for improvement
though a portion or all of the improvement may be attributed to the remedy
• Cessation of unpleasant treatment — often homeopaths recommend patients stop getting
conventional treatment such as surgery or drugs, which can cause unpleasant side effects;
improvements are attributed to homeopathy when the actual cause is the cessation of the
treatment causing side effects in the first place
• Lifestyle changes — homeopaths often recommend diet and exercise, as well as
limitations in alcohol or coffee consumption and stress reduction, all of which can
increase health and decrease symptoms
• The placebo effect — the intensive consultation process and expectations for the
homeopathic preparations can result in the release of endorphins or other body-effecting
chemicals which alleviate pain or other symptoms, or otherwise affect an individual's
biology
• Psychological healing — the care, concern and reassurance provided by a homeopath as
part of the consultation can assure the patient the symptoms are minor and easily treated,
or alleviate tension that could exacerbate a preexisting condition. This caring engagement
can prove particularly effective when conventional physicians have limited time with the
patient or cannot provide a diagnosis or treatment.
Effects in other biological systems
Hampton House, the former site of Bristol Homeopathic Hospital, one of two homeopathic
hospitals run by the NHS.[3]
Homeopathy is fairly common in some countries while being uncommon in others; is highly
regulated in some countries and mostly unregulated in others. It is practised worldwide and
professional qualifications and licences are needed in most countries.[33] Regulations vary in
Europe depending on the country. In some countries, there are no specific legal regulations
concerning the use of homeopathy, while in others, licences or degrees in conventional medicine
from accredited universities are required. In Germany, no specific regulations exist, while
France, Austria and Denmark mandate licences to diagnose any illness or dispense of any
product whose purpose is to treat any illness.[33] Some homeopathic treatment is covered by the
public health service of several European countries, including France, the United Kingdom,
Denmark, and Luxembourg. In other countries, such as Belgium, homeopathy is not covered. In
Austria, the public health service requires scientific proof of effectiveness in order to reimburse
medical treatments and homeopathy is listed as not reimbursable[164] but exceptions can be made;
[165]
private health insurance policies sometimes include homeopathic treatment.[33] The Swiss
government, after a 5-year trial, withdrew homeopathy and four other complementary treatments
in 2005, stating that they did not meet efficacy and cost-effectiveness criteria.[166] The Indian
government recognises homeopathy as one of its national systems of medicine,[167] and a
minimum of a recognised diploma in homeopathy and registration on a state register or the
Central Register of Homoeopathy is required to practice homeopathy in India.[168]
In the United Kingdom, MPs inquired into homeopathy to assess the Government's policy on the
issue, including funding of homeopathy under the National Health Service and government
policy for licensing homeopathic products. The decision by the House of Commons Science and
Technology Committee follows a written explanation from the Government in which it told the
select committee that the licensing regime was not formulated on the basis of scientific evidence.
"The three elements of the licensing regime (for homeopathic products) probably lie outside the
scope of the ... select committee inquiry, because government consideration of scientific
evidence was not the basis for their establishment," the Committee said. The inquiry sought
written evidence and submissions from concerned parties.[169][170]
In February 2010 the House of Commons Science and Technology Committee concluded that:
... the NHS should cease funding homeopathy. It also concludes that the Medicines and
Healthcare products Regulatory Agency (MHRA) should not allow homeopathic product labels
to make medical claims without evidence of efficacy. As they are not medicines, homeopathic
products should no longer be licensed by the MHRA.
The Committee concurred with the Government that the evidence base shows that homeopathy is
not efficacious (that is, it does not work beyond the placebo effect) and that explanations for why
homeopathy would work are scientifically implausible.
The Committee concluded - given that the existing scientific literature showed no good evidence
of efficacy - that further clinical trials of homeopathy could not be justified.
In the Committee’s view, homeopathy is a placebo treatment and the Government should have a
policy on prescribing placebos. The Government is reluctant to address the appropriateness and
ethics of prescribing placebos to patients, which usually relies on some degree of patient
deception. Prescribing of placebos is not consistent with informed patient choice-which the
Government claims is very important-as it means patients do not have all the information needed
to make choice meaningful.
Beyond ethical issues and the integrity of the doctor-patient relationship, prescribing pure
placebos is bad medicine. Their effect is unreliable and unpredictable and cannot form the sole
basis of any treatment on the NHS.[3]
The Committee also stated:
In July 2010 the newly elected UK Secretary of State for Health deferred to local NHS on
funding homeopathy. A nineteen page document details the Government´s response, and it states
that "our continued position on the use of homeopathy within the NHS is that the local NHS and
clinicians, rather than Whitehall, are best placed to make decisions on what treatment is
appropriate for their patients - including complementary or alternative treatments such as
homeopathy - and provide accordingly for those treatments." The response also stated that "the
overriding reason for NHS provision is that homeopathy is available to provide patient choice".
[172]
History
Wikisource has the text of the 1911 Encyclopædia Britannica article Homoeopathy.
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aAIDS denialism • Astrology • Body memory • Bogdanov Affair • Creation Science • Dianetics •
mFaith healing • Homeopathy • Intelligent design • Japhetic theory • Lunar effect • Lysenkoism •
pMelanin theory • Moon landing conspiracy theories • Parapsychology • Perpetual motion •
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