KULWANT KAUR, PhD

6693 Urbandale Lane N - Maple Grove, MN 55311

email: kk8737e8@westpost.net
CLINICAL RESEARCH / SCIENTIST - PHARMACEUTICAL / BIOTECH / HEALTHCARE
Full Lifecycle Clinical Research Leadership - Protocol Development - Regulatory
Compliance
Highly accomplished, analytical professional with history of efficiently managin
g all aspects of complex clinical trials and clinical research. Proven ability t
o deliver highest quality projects on time and within budget. Motivational leade
r, adept at piloting teams in supportive, cooperative laboratory environments. R
esourceful problem solver, driven by new challenges. Adept at increasing workflo
w productivity by multitasking and improving project efficiencies. Areas of expe
rtise include new product development, assay validation, regulatory compliance,
protocol development, and communications. Hands-on experience supported by in-de
pth education. Extensive list of publications and presentations available upon r
equest.
Selected Highlights
-------------------
> Collaborated with pharmaceutical company to successfully develop new human mon
oclonal antibodies against infectious diseases.
> Filed for United States Patent in 2001: "Human monoclonal antibody against Pse
udomonas aeruginosa LPS O-side chain polysaccharide derived from transgenic Xeno
Mouse mice."
> As principal investigator, provided research support to Viking Children's Fund
investigation, "Neonatal production of APRIL and BAFF by dendritic cells and th
eir interactions with TNF family receptors."
Technical Proficiencies
-----------------------
Molecular Biology: DNA Cloning - RNA Isolation - Genomic or Plasmid DNA Isolatio
n - Electrophoresis - DNA Sequencing - Northern and Southern Blots - RT-PCR - Re
al-Time PCR - Recombinant DNA technology
Protein Biochemistry: Protein Expression - Glycoprotein Hemagglutination - Purif
ication and Characterization - Selective Labeling of Protein - Proteolysis Assay
s - Protein-Protein and Protein-DNA Interaction Assays - Radioactive and Non-Rad
ioactive Binding and Cleavage Assays - Western Blots - Chromatography Techniques
and Electrophoresis - Immunoprecipitation
Cell Biology: Immunocytochemistry - Maintenance of Mammalian Cell Culture - Bact
erial Cell Culture - Transfection, Fluorescent, and Confocal Microscopy - Flow C
ytometry FACS Analysis - Cell Proliferation and Viability Assays
Immunology: Animal Techniques - Production and Large-Scale Manufacturing of Mono
clonal and Polyclonal Antibodies - Assays for Lymphocyte Functions - Cytokine an
d Receptors Assays - ELISA - Isolation and In-Vitro Culture of Macrophages, Mono
cytes and Progenitor Cells - Immunoassays

PROFESSIONAL SUMMARY
DEFENSE ADVANCE RESEARCH PROJECT AGENCY (DARPA) Arlington, VA
R&D office for U.S. Department of Defense, which funds unique and innovative res
earch through government labs, private sector, and academic / non-profit organiz
ations
Technical / Healthcare Consultant 2009 to Present
> Analyze status of health care conditions (including infectious diseases) in de
veloping countries to facilitate development of technical strategies for Micro D
iagnostics Program focused on creating innovative, cost-effective, reliable, and
efficient diagnostic devices and methods.
> Assess current U.S. healthcare diagnostic market; compared up to 25 diagnostic
devices, determined customer needs, and recommended new solutions to bridge tec
hnology gaps.
> Conducted industry analyses, addressed technical challenges, and performed mar
ket research.
UNIVERSITY OF MINNESOTA MEDICAL CENTER - FAIRVIEW Minneapolis, MN
One of the Nation's most respected teaching institutions, balancing responsivene
ss to patients' needs with access to innovative treatments and technology 2004
to 2008
Assistant Professor / Instructor (2005 to 2008)
> Efficiently directed Pediatric Infectious Diseases Research Laboratory.
> Developed and served as Principal Investigator on independent research grant;
published paper in Blood, a peer-reviewed journal.
> Evaluated clinical and research data and assessed potential consequences for d
evelopment program.
> Performed specified immunological assays and procedures in accordance with stu
dy protocols / procedures; established clinical methods and standards.
> Developed validated cell-based bioassay protocol for use in R&D and clinical t
rials.
> Served as primary project manager on clinical and preclinical studies; develop
ed detailed study outlines and protocols.
> Optimized performance of study team, helped resolve cell-based assay issues, m
aintained project timelines / milestones, and reviewed results.
> Directed team that conducted basic, applied, and clinical research in coordina
tion with staff of local hospital; develop efficient record-keeping system, and
assessed performance of team members.
Senior Research Associate (2004 to 2005)
> Managed clinical study sites; ensured timely and effective communication and t
roubleshooting, and provided recommendations to optimize all aspects of clinical
studies. Completed project on time.
> Collected and analyzed data, scheduled and supervised clinical projects, and r
eviewed team.
> Provided daily leadership to studies; ensured on time, within budget delivery
of projects that complied with grant specifications.
> Helped track patient enrollment and study progress; created and reviewed sourc
e documents and ensured timely collection and submission of study data.
> Contributed to hiring, scheduling, management, and training of technical staff
; conducted performance reviews.
> Developed positive working relationships with research nurses and other labora
tory team members.
> Created QA system for laboratory processes and established laboratory biosafet
y, waste management, and SOPs. Passed annual audits without incident.
RAINBOW BABIES & CHILDREN HOSPITAL AT CWRU Cleveland, OH
Dedicated pediatric hospital / academic medical center that offers cutting-edge
therapies to children 1999 to 2004
Research Associate
> Developed and designed new assay and experimental strategies for clinical rese
arch. Coordinated and performed laboratory research within infectious diseases r
esearch group; outcome secured new NIH grant for lab.
> Developed human monoclonal antibodies against Pseudomonas Aeruginosa in collab
oration with Abgenix Inc.; carried out leading antibodies from early cloning sta
ges through preclinical development, which led to U.S. patent for antibodies.
> Conducted laboratory experiments on newly developed monoclonal antibodies afte
r large-scale production and purification, which resulted in three research publ
ications.
> Executed troubleshooting on research procedures, created experimental designs,
and maintained lab equipment.
> Managed all samples analysis, including tissue culture, set-up, harvesting, im
aging, and statistical.
> Adhered to QC and safety procedures while supporting evaluation of protocols f
or relevance.
> Supervised and trained up to six technical personnel and students.

EDUCATION & PROFESSIONAL DEVELOPMENT

GND University - Amritsar, India
PhD - Molecular Biology and Biochemistry
Master of Philosophy - Molecular Biology and Biochemistry
Master of Science - Human Biology
University of Minnesota - Minneapolis
Master of Science - Management of Technology