CURRICULUM VITAE

Patricia Susana Pardo PhD

Home: 1205 Autrey St Apt 16
Houston TX 77006
713-301-8205
ppa1e03e@westpost.net
Education and Degrees:
PhD in Chemistry
School of Exact and Natural Sciences,
University of Buenos Aires, Argentina

Graduated in Biological Sciences

School of Exact and Natural Sciences,
University of Buenos Aires, Argentina.
Professional Experience:
2005-May 2010: Research Associate, Department of Medicine, Pulmonary Division, B
aylor College of Medicine. (PI: Aladin Boriek PhD)
1999-2004: Postdoctoral Associate, Huffington Center on Aging, Baylor College of
Medicine. (PI: Olivia Pereira Smith PhD, 1999-2001, Fred A. Pereira PhD, 2001-2
004)
1990-1999: Instructor at Microbiology, Department of Ecology. Faculty of Agronom
y, University of Buenos Aires.(PI: Susana Passeron PhD)
Fellowships and Awards:
Award to Scientific Production, Ministry of Economy, Argentina.
Fellowship of the National Council of Scientific and Technological Research (CON
ICET), Argentina.
Fellowship of the Comission of Scientific Investigation, Province of Buenos Air
es(SIC), Argentina
Publications:
1) Pardo, P. S., Lopez, M. A., Mohamed J. S and Boriek, A. M. Induction of Sirt1
by mechanical stretch of skeletal muscle through the early response factor Egr1
is involved in an antioxidative response. Accepted with minor revisions. Journa
l of Biological Chemistryl.
2) Lopez MA, Pardo PS, Cox GA, Boriek AM (2008) Early mechanical dysfunction of
the diaphragm in the muscular dystrophy with myositis (Ttnmdm) model. Am J Physi
ol Cell Physiol. 295:C1092-102.
3) Pardo, P. S., Lopez, M. A. and Boriek, A. M (2008). The FOXO Transcription fa
ctors are mechanosensitive and their regulation is altered in the respiratory pu
mp. Am J Physiol Cell Physiol. 294:C1056-66.
4) Pardo P. S. , Leung J. K. , Lucchesi J. C. , Pereira-Smith O. M. (2002) MRG15
, a novel chromodomain protein, is present in two distinct multiprotein complexe
s involved in transcriptional activation. J. Biol. Chem. 277: 50860-50866.
5) Pardo, P. , Zelada, A. M. and Passeron, S. (2002) In vivo and in vitro phosph
orylation of Candida albicans 20S proteasome. P. Fernandez Murray. Archives of B
iochemistry and Byophisics 404, 116-125.
6) Raina, A. K., Pardo, P., Rottkamp, C.A., Zhu, X., Pereira Smith, O. M. and Sm
ith, M. A. (2001) Neurons is Alzheimer Disease emerge from senescence. Mechanism
of Ageing and Development.123, 3-9.
7) Pardo, P*, Fernandez Murray*P., Walz, K., Franco, L. and Passeron, S. (1998)
In vivo and in vitro Phosphorylation of the *7/PRS1 Subunit of Saccharomyces ce
revisiae 20S proteasome: In vitro Phosphorylation by Protein Kinase CK2 is Absol
utely Dependent on Polylysine. Archives of Biochemistry and Biophysics 349:2, 39
7-401. (*, equal contribution)
8) K. Walz*, P. Pardo*, and S. Passeron (1997). Purification and Characterizatio
n of Protein Kinase CK2 from Candida albicans. Archives of Biochemistry and Biop
hysics 340:2, 347-354. (*, equal contribution).
9) Pucheu, N. L. Kerber, N. L., Pardo P., Brand, M., Drews G. and Augusto Garca
(1996) Bionergetic factors controlling in vitro phosphorylation of LHI a (B 870
) polypeptides in membranes isolated from Rhodobacter capsulatus. Archives of. M
icrobiology 165, 119-125.
10) Pardo, P. and Moreno, S. (1988). Characterization of two casein kinase activ
ities in the fungus Mucor rouxii, Second messengers and phosphoproteins, 12(4),
183-196
Unpublished manuscripts
1) Pardo, P. S, Montemayor, C. and Pereira F. A. Orphan nuclear receptors in ne
uroendocrine metabolism: involvement in aging and age-related diseases.
2) Pardo, P. S., Yotnda, P., Ling, F., Liu, Y. and Pereira, F. A. COUP-TFI lo
ss of function affects the normal progression through mitosis in mouse embryonic
fibroblasts.
Scientific societies membership
AAAS: member since 2007.
Sigma Psi: full member since 2007
Whos who: full member since 2009
Technical Skills
RNA and DNA: molecular cloning, site-direct mutagenesis, RNA/DNA purification, R
T-PCR, real time PCR, chromatin immunoprecipitation. EMSA.
Protein: bacterial expression and purification; western blot, co-immunoprecipita
tion.
Tissue culture: cell culture, transfection, viral production (lentivirus, retrov
irus), viral infection, immunohistochemistry.
Microbiology techniques: bacterial and yeasts culture,
Microscopy: fluorescence, deconvolution and confocal microscopy.
Others: flow cytometry.

Supervision of students research

Summer 2008: Tyler Merceron, SMART Program, Baylor College of Medicine, Huffingt
on Center on Aging.
Summer 2003: John Kwon, SMART Program, Baylor College of Medicine, Department of
Medicine.
Teaching
Courses
Undergraduate Courses:
1) Molecular Biology, School of Exact and Natural Sciences, University of Buenos
Aires, Department of Biological Chemistry.
2) Biological Chemistry. School of Exact and Natural Sciences, University of Bue
nos Aires, Department of Biological Chemistry.
3) Biological Chemistry II, School of Exact and Natural Sciences, University of
Buenos Aires, Department of Biological Chemistry.
4) Microbiology, School of Agronomy, University of Buenos Aires.
Graduate Courses
5) Biochemistry, Magister in Animal Health, School of Veterinary, University of
Buenos Aires (invited lecturer).
6) Energetic Metabolism of Microorganism, Magister in Biotechnology, University
of Buenos Aires.
7) Signal Transduction in Cellular Biology, Phosphorylation and Second Messenger
s", School of Medical Sciences, National University of Cuyo, Argentina (invited
lecturer).
8) Advances in Molecular Biology, School of Agronomy (Graduate School), Universi
ty of Buenos Aires.

Languages: Spanish and English

Immigration Status: Permanent Resident