Beruflich Dokumente
Kultur Dokumente
Professional Experience
Genomics Product Specialist
Vector Biotechnologies
US Northern Midwest territory
September 13th 2010-Present
Sales of Agilent Technologies genomic products and services
Cytogenetics/Microarry Technologist
Childrens Mercy Hospital
Kansas City, MO
May 2007-September 2010
Perform clinical aCGH (microarray-based Comparative Genomic Hybridization) stud
ies analyzing genetic copy number variants
Perform clinical chromosome analysis
Perform development studies improving clinical diagnostic microarray and PCR co
nfirmation tests
Manage microarray lab: inventory, specimens, data, disseminate findings to pro
fessional colleagues and physicians
Scientist I - Enzyme Induction, In-vitro division
XenoTech L.L.C.
Lenexa, KS
June 2006-May 2007
LAB FOCUS:
Pharmaceutical Research & Development studies
DUTIES:
-Perform In Vitro experiments analyzing human hepatocytes for toxicological effe
cts and enzyme induction of Cytochrome P450 by new chemical entities
-Isolation of Microsomes from hepatocyte cells
-Serve as Lead Scientist on studies
-Liver perfusion On-Call team, EI Culture Queue Expert
Senior Research Laboratory Technician
University of Missouri-Columbia
June 2001-July 2005
LAB FOCUS:
Improve current anti-cancer drugs
Identify breast cancer biomarkers
Proteomic analysis of dog lymphoma tumors
DUTIES:
-Assist lab personnel with experiments
-Maintain radioactive and hazardous materials
-Maintain cell cultures, supplies, budget and equipment
-Supervise and Interview Junior/Undergraduate lab members
Publications
Yu S, Fiedler S, Stegner A, Graf WD. Genomic profile of copy number variants on
the short arm of human chromosome 8. European Journal of Human Genetics. 2010
May 12.
Yu S, Kielt M, Stegner AL, Kibiryeva N, Bittel DC, Cooley LD. Quantitative real-
time polymerase chain reaction for the verification of genomic imbalances detect
ed by microarray-based comparative genomic hybridization.Genetic Testing Molecul
ar Biomarkers. 2009 Dec;13(6):751-60.
McCaw DL, Chan AS, Stegner AL, Mooney B, Bryan JN, Turnquist SE, Henry CJ, Alexa
nder H, Alexander S. Proteomics of canine lymphoma identifies potential cancer-
specific protein markers. Clinical Cancer Research: an official journal of the
American association for Cancer Research. 2007 April 15;13(8):2496-503.
Min J, Traynor D, Stegner AL, Zhang L, Hanigan MH, Alexander H, Alexander S. Sph
ingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to t
he anticancer drug cisplatin. Eukaryotic Cell. 2005 January;4(1):178-89
Alexander H, Stegner AL, Wagner-Mann C, Du Bois GC, Alexander S, Sauter ER. Prot
eomic analysis to identify breast cancer biomarkers in nipple aspirate fluid. Cl
inical Cancer Research: and official journal of the American association for Can
cer Research. 2004 November 15;10(22):7500-10
Min J, Stegner AL, Alexander H, Alexander S. Overexpression of sphingosine-1-pho
sphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum res
ults in a selective increase in sensitivity to platinum-based chemotherapy drugs
. Eukaryotic Cell. 2004 June;3(3):795-805