SigmaPlot 12.0 Copyright 2010 Systat Software, Inc.

. All Rights Reserved ============================================== System Requirements =================== Hardware -------Windows 7 or Windows Vista: 1 GHz 32-bit (x86) or 64-bit (x64) processor, 1 GB o f system memory, 100 MB of available hard disk space. Windows XP: 500 megahertz (MHz) processor, 256 MB of system memory, 100 MB of av ailable hard disk space All Operating Systems: CD-ROM drive, 800x600 SVGA/256 color display or better. Software -------Windows XP, Windows Vista, Windows 7; Internet Explorer 6 or higher; Office 2003 or higher (paste to PowerPoint Slide, Insert Graphs into Word and other macros) . Known issues =========== Pasting graphs into Excel ------------------------If you paste a SigmaPlot graph into Excel and want to edit the graph, right-clic k on the graph and select Edit from the SPW 12.0 Graph Object submenu. Do not double-click to edit the graph since this will cause both Excel and Sigma Plot programs to stop responding.

New Features and Improvements in SigmaPlot 12 ============================================== Microsoft Office Style Ribbons ------------------------------Context sensitive feature grouping for enhanced functionality and ease of use. -Expanded tooltips that include hot keys. -High resolution button icons. -Alt Key Tips provide visual display of keyboard shortcuts. New Property Browser --------------------New graph object and property browser. Object selection in the graph is displa yed in the object window and the object s properties displayed in the property win dow. -Dynamic Update provides immediate graph redraw with property change. No Ok or Apply button press required. -Property group styles may be copied and applied across like groups thus simplif ying property specification.

-New window show/hide buttons for window real-estate management. User Interface Improvements ---------------------------New tabbed window views enables quick window management (selection, closing, gr ouping) -New docking panel guides providing simple window placement. This includes the Graph Gallery, Templates, Layouts, Object and Properties windows. -Group open windows into tabbed groups either vertically or horizontally. This collects like windows for easy comparison and better window management. -Object-specific mini toolbars are displayed adjacent to selected graph, workshe et and report objects. This allows rapid editing of object properties. -Customizable Quick Access Toolbar for frequently used user-specific controls. -Improved Graph Page Navigation -Zoom, pan, +/- controls and zoom dialog & slider always available on status bar . -Drag graph with "hand" mouse cursor. -Quick window scrolling with middle mouse wheel. Worksheet Improvements ----------------------Mini tool bar for worksheet cell editing. -Zoom enabled worksheet. -Quick Transforms list in Property Browser Object Window. -Quick worksheet window scrolling with middle mouse wheel. -Formatted text in worksheet cells. Text in worksheet can contain super and sub scripts, Greek letters, etc. and this can be used in tick labels. -Report Improvements -Insert tables with pre-defined styles or customize completely. -Copy/Paste tabular data both ways between the SigmaPlot report and Excel worksh eet. -Zoom enabled report. -Vertical and horizontal rulers. -Ability to change the report background color -Explicit icon in Graph Output ribbon for frequently used PDF export which is en hanced by a new version of the report engine. -Drag and Drop Word 2007 and Word 2010 content directly to the report page. New Curve Fitting Features --------------------------Weight variables may now be specified quite generally as functions of the param eters. Therefore these weights will change at each iteration. As special case s this includes weighting by predicted values, weighting as a function of residu als (for robust regression) and weighting as any function of the parameters. -Parameter covariance matrix and parameter confidence intervals added to nonline ar regression reports. -Implicit function curve fitting gives the ability to compute predicted values t hat are defined implicitly by the fit model. New Statistics Features -----------------------Non-parametric one sample t-test. -Deming regression allows for errors in both x and y variables a technique for m ethod comparison. -Normal distribution comparison with graph and statistics for preliminary qualit y control analysis. -Parallel line analysis to determine if linear regression slopes and intercepts are different. -Bland-Altman graph and statistics for method comparison. -Improvements in post-hoc testing for multi-factor ANOVAs including P-values for

Dunnett s test and more accurate statistics for multiple comparisons in 3-Way ANO VA. -New Analysis and Transform Language Features -Enzyme kinetics analysis module included. -Worksheet row and column titles may now be set from the Transform language stat ements. -New Root() and Implicit() functions for solving equations. New Graphing Features ---------------------GDI+ support to provide enhanced graphics features. -Color gradients available for almost all objects including area fills and lines . -Anti-aliasing eliminates jagged lines. -Area object and line transparency -Radar graph with sub-types: scatter, line, vector, area, line & error band -Dot histogram graph -ScaleGraph macro that allows scrolling through time-series data. Application Support Features ----------------------------Automatic transfer of Version 12 user options during software upgrade. Macro Support Features ----------------------Graph page measurement units specification. -Automatic legend state specification. Accessibility ============= Window 7 -------Open the command window (cmd.exe), navigate to the CD directory "SigmaPlot". Typ e setup.exe and hit the return key. Windows XP ---------To install SigmaPlot without using the initial autoplay menus, from the Windows Start menu, select Run and type: d:\SigmaPlot\Setup.exe (where d: is the CD drive letter)

============================================= For more information, see www.SigmaPlot.com =============================================