Pathophysiology Quiz 1/22/09

Single Best Answer

1. Choose the ONE BEST answer.

Which of the following is demonstrated by the curves below?

M fig 9-18 p. 233

A. B. C. D. E.

Regardless of pCO2, ventilation decreases with decreased pO2 Regardless of pCO2, ventilation increases with increasing pO2 Regardless of pO2, ventilation decreases with increased pCO2 Regardless of pO2, ventilation increases with increasing pCO2 Ventilation is independent of pCO2 if pO2 is held constant

2. Proprioceptors from the muscles of respiration sent signals to which of the following? A. Cerebellum B. Cerebrum C. Lung and upper airways

2 D. Medulla E. Spinal cord 3. Based on Poiseuilles Law, which of the following is the principal determinant of resistance in the lung under conditions of laminar flow? A. B. C. D. E. Airway caliber Flow rate Gas density Gas temperature Gas viscoisty

4. A. B. C. D. E.

Which of the following cell types makes surfactant? Columnar epithelium Cuboidal epithelium Squamous epithelium Mesothelium Mononuclear phagocyte

Matching

Choices may be used once, more than once, or not at all.

Match each organism with its preferred treatment. A. B. C. D. E. 5. 6. Cephalosporin Clindamycin Erythromycin Tobramycin + ticarcillin Trimethoprim + sulfamethoxazole Mycoplasma Klebsiella

Match each person with the spirometry values he/she is most likely to have (even if you would not really do pulmonary function testing on this person). I = Increased FEV1 A. B. C. D. E. D = decreased FVC FEV1/FVC N = normal TLC RV TV

7. 56 year old man from Russia who has cough productive of bloody sputum, weight loss, night sweats, and chest pain with a low grade fever for four months. His ABGs show hypoxia and hypocapnea. 8. 58 year old man who suffered smoke inhalation and who now has severe bilateral noncardiogenic pulmonary edema and is about to be intubated and mechanically ventilated. His ABGs show hypoxia and hypercapnea.

Match each organism with the sputum it is most likely to produce. A. B. C. D. E. Foamy white Green purulent No sputum Red jelly Rusty purulent

9.

Streptococcus pneumoniae

10. Pneumocystis jiroveci (carinii) Match each person with the description of the organism most likely to cause their illness. A. B. C. D. E. Acid fast bacilli Aerobic encapsulated Gram positive diploccocci Anaerobic Gram positive cocci Gram negative rods Will not stain

11. 12.

12 year old girl with sickle cell disease has had repeated bouts of pneumonia 12 year old boy with cystic fibrosis has had repeated bouts of pneumonia

Match each person with the chest x-ray he/she is most likely to have. A. B. C. D. E. Bilateral hazy ground glass appearance Bilateral microabscesses Left upper lobe thick-walled cavity Left lower lobe infiltrate Right middle lobe cavity with air-fluid level

13. 66 year old veteran who recently attended a square dance convention and now has diarrhea and nonproductive cough and malaise. He has heard that several of his friends who also were at the meeting are sick too. 14. 45 year old homeless man who has had 2 months of productive cough, low grade fever and night sweats. 15. 24 year old woman who has been coughing, coughing, coughing, coughing, coughing uncontrollably for four days. She has a low grade fever and malaise but doesnt feel so bad that she cant continue her daily routine.

Match each person with the arterial blood gases he or she is most likely to have. pH 7.4 A. B. C. D. E. 7.38 7.38 7.38 7.44 7.44 PCO2 35-45 28 64 64 28 64 PO2 90-100 78 58 84 78 84 HCO322-26 18 24 34 24 34

16. 14 year old boy who began having an asthma attack a half hour ago is on his way to the ER 17. 54 year old woman with productive cough, chest pain and fever for two days.

18. 67 year old man who has smoked 2 packs of cigarettes daily for 50 years presents with chronic productive cough, barrel chest, cyanotic fingertips and lips, prolonged expiration, but is feeling his usual state of health, no worse.

Match each adverse effect with the drug which is most likely to cause it. A. B. C. D. E. 19. 20. Albuterol Beclomethasone Ipatropium Rifampin Streptomycin Hearing loss Tachycardia

21. Thrombocytopenia Match each mechanism of action with the drug that does it. A. B. C. D. E. Albuterol Montelukast Rifampin Streptomycin Tiotropium

22. 23.

Competitive inhibition of muscarinic receptors Inhibit B subunit of bacterial RNA polymerase

Match each location on the spirogram with the most appropriate descriptive phrase.

24. 25.

Amount of air that can be inhaled after a normal exhalation. Amount of air in the lungs after a maximal exhalation