Beruflich Dokumente
Kultur Dokumente
Global Health Concepts Copyright: Anthony Musso- All Rights Reserved- 2011
Index Chapter 1: Berberine History and Synopsis Chapter 2: Use in Diabetes Treatments Chapter 3: Use in Cholesterol Reduction Chapter 4: Use in Dysentery (Diarrhea) Chapter 5: Use in Bacterial Infection Chapter6: Use in Liver Function Treatment Chapter 7: Use in Critical Disease: Malaria and Dengue Chapter 8: Fever Reduction Combination Therapy Chapter 9: Artemisinin, Berberine Plus Other Compounds A. Summary
B. C.
D. Certificates of Analysis
E.
Note to Readers:
I have been working with Berberine Alkaloid for almost 6 years while based out of Asia. I have been the first person to combine it with Artemisinin which is another powerful plant concentrate (Artemisia Annua Botanical) used to treat severe fever in Mainland China for over 2000 years. Both Berberine and Artemisinin concentrates have extensive use historically as individual concentrates or simply in raw plant form soaked in water and used for drinking in tea form but always consumed for medical benefit purposes. I created this free E Book for people from the over 220 countries who need a self-medication type treatment that is safe and works while using it for major medical problems ranging from Diabetes to Dysentery, Malaria and Dengue Fever.. The fact is that I have had so many requests for information on Berberine and its potential uses and combinations that I believe it is now mandatory for me to divulge this important information and have it disseminated and readily available to the general public and medical practitioners who are interested in unique, safe natural cures and remedies that work. This will be available online and in a downloadable free mobile application shortly. Any questions or comments anthonymusso@gmail.com or requests please email to:
barberry root bark (Berberis vulgaris), Oregon grape root (Berberis aquifolium), and goldenseal root (Hydrastis canadensis). Berberine was isolated and used as an herbal medicine in China 50 years ago (the drug forms are usually the hydrochloride or sulfate; the chloride, as used in the dye, may have the strongest antiseptic action). It has since become an ingredient in several Western herbal products, particularly for treatment of intestinal infections. Coptis and phellodendron have been used in China for treating gastrointestinal diseases with reported success; applications have included acute gastroenteritis, cholera, and bacillary dysentery. So, the first applications of isolated Berberine were for treatment of these conditions. Recent clinical trials have yielded conflicting results as to which of the disease organisms causing intestinal symptoms are responsive to Berberine (1, 2). Tests of the antiseptic action of Berberine against bacteria, yeasts, viruses, and amoebas have shown a range of activity levels from apparent potent action to mild suppression. Inhibition of giardia and of candida have been areas of considerable interest and initial positive research results have led to development of several herb products for those applications.
Soon after Berberine was prepared as an isolated agent for clinical use, it was noted that Berberine had other potential benefits; for example, it appeared to reduce high blood pressure at doses of about 1 gram per day (3). The hypotensive action of Berberine has been confirmed in several pharmacology experiments, but follow-up clinical trials have been lacking. Still, this effect of Berberine fortunately led to further testing of the compound for patients with cardiovascular disease risk factors, and evidence developed to demonstrate a lowering of cholesterol (and triglycerides) and of blood sugar. These new findings are the main focus of this brief report. CHOLESTEROL: There has been increased interest in lowering blood cholesterol, and especially LDL-cholesterol, as a means of curtailing the high rates of heart attack and stroke. In addition to recommended dietary changes, many people are prescribed statin drugs for this goal. The statin drugs are powerful, frequently effective, and may have other benefits, though they also pose certain risks. During the 1990s, the Chinese herb material "red rice yeast" (Monascus purpureus) was sold in the U.S. as a natural supplement that contains, as one of its active ingredients, small amounts of lovastatin, one of the widely used statin drugs (it also contains several related compounds that contributed to the cholesterol lowering action). After prolonged legal disputes between the supplement providers, the drug companies, and the FDA about its content of the drug substance, the sale of red rice yeast and its extracts as natural cholesterol has limited distribution and availability..
It was reported recently that Berberine lowers cholesterol through a mechanism different than that of the statin drugs, suggesting potential use both as an alternative to the statins and as a complementary therapy that might be used with statins in an attempt to gain better control over cholesterol. In a controlled Chinese study (4), it was shown that Berberine, administered 500 mg twice per day for 3 months, reduced serum cholesterol by 29%, triglycerides by 35% and LDL-cholesterol by 25%. The apparent mechanism is increasing the production of a receptor protein in the liver that binds the LDL-cholesterol, preparing it for elimination. BLOOD SUGAR: Research on use of Berberine for diabetes began with Ni Yanxi and his colleagues in Changchun (a large city in Jilin Province) with diabetes treatments. As an introduction to a 1995 English language publication on this subject (presenting their earlier clinical data from 1983-1987), they wrote (5): "It was found by accident that berberine had the therapeutic effect on the decrease of blood glucose when the authors used berberine to treat diarrhea in patients who suffered from diabetes." Dietary therapy was first introduced to the patients for one month. For those who still had high fasting blood sugar, berberine was administered orally at a dose of 300, 400, or 500 mg each time, three times daily, adjusting the dosage according to the blood glucose levels; this treatment was followed for 1-3 months. A control group without diabetes was similarly treated, with no effect on blood sugar. For the diabetic patients, it was reported that patients had less thirst, consumed less water and urinated less, had improved strength, and had lower blood pressure; the symptoms declined in correspondence with declining blood glucose levels. Laboratory studies suggest that berberine may have at least two functions in relation to reducing blood sugar: inhibiting absorption of sugars from the intestine and enhancing production of insulin. As relayed by Ni in his review of the literature, clinical experience with berberine has shown that doses of 2 grams per day produced no side effects. Berberine Indications For treatment and cure of fungus infections and yeast infections, especially systemic, chronic, or recurrent fungus infection and yeast infection caused by Candida albicans intestinal yeast overgrowth (Candidiasis). For treatments addressing the symptoms of Candida albicans intestinal yeast infection. In men and women for addressing underlying causes of fungus and yeast-related disorders including oral yeast infection (thrush), vaginal yeast infection (vaginitis) and male yeast infection (jock itch). For treatment and supportive therapy of intestinal disorders commonly associated with Candida albicans yeast overgrowth (Candidiasis) including Irritable Bowel Syndrome (IBS), leaky gut syndrome, intestinal parasite infections, and intestinal bacterial infections.
Berberine Source & Availability: Berberine is a natural, herbal, botanical dietary supplement commonly available in pill, tablet, or capsule form. Berberine is an alkaloid found in various plants, including goldenseal, barberry, Oregon grape, and goldthread. Berberine exhibits a broad spectrum of antibiotic activity in test-tube, animal, and human studies. Berberine Medicinal Value; Berberine-containing plants are used medicinally in virtually all traditional medical systems, and have a history of usage in Ayurveda (Hindu) and Chinese medicine dating back at least 3,000 years. Berberine has demonstrated significant antimicrobial activity against bacteria, fungi, yeast, protozoans (Giardia, etc.), viruses, helminthes (worms) and chlamydia. In addition, Berberine's actions include: antagonism of the effects of cholera and E. coli toxin, inhibition of intestinal ion secretion, inhibition of smooth muscle contraction (spasms), and reduction of inflammation. Berberine's most common clinical uses include: bacterial diarrhea and intestinal parasites.
Probably the most extensive global use of Berberine Alkaloid is for the prevention and control of Diarrhea ranging from mild to severe forms. One can see quite rapidly how effective Berberine is for healing Diarrhea within 30 minutes to 3 hours of taking an adequate dose. It appears to directly treat the underlying causes of the condition unlike the over the counter drugs and synthetic medicines that only mask the problem and provide moderate or no comfort. GI tract and gas pains are rapidly diminished and dehydration is stopped.
Many clinical studies have been completed simply because the obvious physical effectiveness of the compound has excited so many researchers and scientists over
many decades of use in many countries, especially Asia since it is processed on an industrial scale in China. Relatively little is known in the USA or Europe about Berberine and its practical uses due to the fact that the Pharmaceutical companies have a stronghold on the information and distribution of products used to treat Diarrhea. Nurses are especially shocked to see how well it works on so many disease states and how simple it is to apply as a non-toxic substance. For Globe Trotting Travelers, Berberine and certain proprietary combinations including Artemisinin can be a miracle treatment in an emergency away from home. There is nothing worse than having your vacation time destroyed by rampant Diarrhea. I advise world travelers to take the Berberine combination compounds starting on the day they leave on their trip. It is an excellent preventative.
Another significant use of Berberine Alkaloid in in the use of treating bacterial infections ranging from Eye Infections including Conjunctivitis, Ear Infections, Tooth Infections and Urinary Tract Infections.
Clinical studies have verified the usefulness of Berberine Alkaloid to treat infections.
Summary
ON a personal note,
acquaintance I meet when they ask what do I do and after explaining about these amazing herbal concentrates and remedies is: Do you use these formulas ? Even if they do not answer I inform them quite definitively that I would not let anyone in my family travel to another country without taking these substances with them and also I educate them in their use. My children take these products regularly when fever shows up or they have the possibility of some disease such as Dysentery, Dengue or Malaria while traveling and living in Asian countries like the Philippines. I recommend everyone carry these ingredients in pill, capsule or powder form in their medicine cabinets and first aid kits like I do everywhere I travel. Even eating first class Sushi restaurant is quite risky as I found out one time in Boston, Mass.
Note: There are well over 500 studies done on Berberine Alkaloid. The following is a sampling of those studies.
Many more are in process due to the extreme significance of this compound and its effectiveness in so many areas of health and wellness. It is worth your while to read any relevant studies on conditions you are interested in knowing about.
References:
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