Master Bio Medical Engineering Guide Aug 09

Biomedical Engineering MSc programme Study Guide 2009/2010 www.bme.tudelft.
nl
BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p1/41
Disclaimer
This study guide has been compiled with the utmost care and is based on information provided by the faculties; this information was current on July 9, 2009. For the most recent information please visit CourseBase; the Universitys on-line course information system, at www.studiegids.tudelft.nl.
Content
Preface....................................................................................................................................... 5 1. 2. 3. 4. Introduction........................................................................................................................ 7 Goals.................................................................................................................................. 9 Qualifications of MSc in BME graduates ............................................................................... 10 Study programme.............................................................................................................. 11 4.1 4.1.1 4.1.2 4.1.3 4.2 4.2.1 4.3 4.3.1 4.3.2 4.3.3 4.3.4 4.4 5. 5.1 5.1.1 5.1.2 5.2 5.2.1 5.2.2 5.3 5.3.1 5.3.2 5.4 5.4.1 5.4.2 5.5 5.5.1 5.5.2 5.6 5.6.1 5.6.2 5.7 General information ................................................................................................... 11 Semesters and periods ........................................................................................... 11 Examinations......................................................................................................... 11 Study load and European Credits ............................................................................ 11 MSc: first year (60 EC) ............................................................................................... 12 Individual Study Programme (ISP) .......................................................................... 12 MSc: second year (60 EC) .......................................................................................... 13 Traineeship in a hospital, industry or other research institute (12 EC)......................... 13 Literature survey (10 EC) ....................................................................................... 13 Masters thesis project (38 EC) ................................................................................ 14 Oral presentations ................................................................................................. 14 Student interviews ..................................................................................................... 14 Medical Instruments & Medical Safety (MIMS).............................................................. 16 Overview .............................................................................................................. 16 Admission ............................................................................................................. 16 Biomechatronics (BM) ................................................................................................ 17 Overview .............................................................................................................. 17 Admission ............................................................................................................. 17 Tissue Biomechanics and Implants (TBI) ..................................................................... 18 Overview .............................................................................................................. 18 Admission ............................................................................................................. 18 Medical Imaging (MI)................................................................................................. 19 Overview .............................................................................................................. 19 Admission ............................................................................................................. 19 Medical Physics (MP).................................................................................................. 20 Overview .............................................................................................................. 20 Admission ............................................................................................................. 20 Biomedical Instrumentation (BI) ................................................................................. 21 Overview .............................................................................................................. 21 Admission ............................................................................................................. 21 Annotation Entrepreneurship ...................................................................................... 21
Specialisations within the MSc in BME programme................................................................ 15
6.
Admission ......................................................................................................................... 22 6.1 Admission for students with an academic bachelors degree ........................................... 22 6.1.1 Additional Bachelors courses for admission to Medical Instruments and Medical Safety (MIMS) and Biomechatronics (BM) ...................................................................................... 23 6.1.2 6.1.3 (MP) 6.1.4 6.2 6.2.1 Additional Bachelors Courses for admission to Tissue Biomechanics and Implants (TBI)23 Additional Bachelors Courses for admission to Medical Imaging (MI) and Medical Physics 24 Additional Bachelors Courses for admission to Biomedical Instruments (BI) ................ 24 Admission for students with a bachelors degree from a Dutch polytechnic school (TH/HBO) 25 Introduction .......................................................................................................... 25
6.2.2 Pre-masters programme for Medical Instruments and Medical Safety (MIMS); Biomechatronics (BM); and Tissue Biomechanics and Implants (TBI) ..................................... 26 6.2.3 6.2.4 6.3 7. 7.1 7.2 8. 8.1 8.2 9. 10. 10.1 10.2 10.3 10.4 10.5 11. 11.1 11.2 11.3 11.4 11.5 11.6 11.7 11.8 12. Pre-masters programme for Medical Imaging (MI) and Medical Physics (MP) .............. 27 Pre-masters programme for Biomedical Instruments (BI) .......................................... 28 Admission for students still in their academic bachelors programme ............................... 29 Courses in Leiden ...................................................................................................... 30 Courses in Rotterdam................................................................................................. 31 Biomedical courses .................................................................................................... 33 Mathematics and Engineering courses ......................................................................... 35 Enrolling for courses and tests, pass rules........................................................................ 37 Courses .................................................................................................................... 37 Tests ........................................................................................................................ 37 Pass rules ................................................................................................................. 37 Examination .............................................................................................................. 37 Cum laude ............................................................................................................... 37 Organisation ................................................................................................................. 38 Faculty 3ME .............................................................................................................. 38 Interfaculty masters programme ................................................................................. 38 Education support staff .............................................................................................. 38 Education committee ................................................................................................. 39 Board of Examiners.................................................................................................... 39 Student association.................................................................................................... 39 MSc coordinator ........................................................................................................ 39 Academic Counsellor .................................................................................................. 40 Further Information ....................................................................................................... 41
Teaching in Leiden (LUMC) and Rotterdam (Erasmus MC)..................................................... 30
All BME masters courses .................................................................................................... 32
Study and traineeship abroad ............................................................................................. 36
Preface
We are very pleased that the MSc programme in Biomedical Engineering will start on 1 September 2009 for the sixth year. Meanwhile many students were awarded their MSc degrees and most of them found that the course was exactly what they were looking for: challenging, interesting, relevant, multi-disciplinary, application-oriented and more. Almost all of them have been able to find rewarding jobs in the biomedical industry or in related fields, mostly as researchers or designers. In 2007 we received a visit from an evaluation committee which is responsible for monitoring the quality of the education programme. The committee members were very enthusiastic about the multidisciplinary character of the course, offered in collaboration with Leiden University Medical Centre and the Erasmus Medical Centre in Rotterdam. They were particularly in favour of the use of direct confrontation with clinical research issues as the main tool for keeping the students focused. The unique collaboration between the departments of Applied Sciences, Electrical Engineering and Mechanical Engineering in an interfaculty MSc programme does present challenges in terms of the lecture schedules and examinations etc. However, on the positive side, students are encouraged to look beyond the traditional boundaries of the individual disciplines and to discover new horizons. The contribution made by our clinical partners at the Leiden University Medical Centre (LUMC) and the Erasmus Medical Centre in Rotterdam (ErasmusMC) is very important. Medical doctors from the centres visit the Delft campus and introduce the BME students to the clinical problems that they are facing. The future BME engineers make several trips to Leiden and Rotterdam in order to gain direct experience of the clinical environment and many BME students carry out their MSc thesis assignments or at least part of them at the Leiden and Rotterdam sites. As an indication of the positive nature of the collaboration, during the last years some medical students have also come to Delft to take an introductory course in Biomedical Engineering. Medical doctors with a good appreciation of engineering methodology and design are very important as a counterpart to the BME engineers. This coming year more medical students are likely to spend part of their study time at Delft. In 2006 an official collaboration programme involving the LUMC, the University of Leiden, ErasmusMC, Erasmus University and Delft University of Technology began. This regional collaboration between three large knowledge institutes will act as a major stimulus for biomedical companies in the province of South Holland, which is referred to as the Medical Delta www.medicaldelta.nl. The collaboration involves both research and education. For new MSc students in particular it represents an ongoing commitment on the part of our clinical partners to participate in the education programme. In addition new jobs will be created in the region for our graduates.
The BME programme at Delft University of Technology differs from other BME programmes offered in the Netherlands, because it focuses on producing good engineers in the traditional engineering disciplines who can apply their skills within multi-disciplinary research teams which also include medical scientists. The MSc course puts the emphasis on multi-disciplinary collaboration and the MSc theses are under the guidance of both technical and clinical tutors. In the field of biomedical engineering there are still many new discoveries to be made and there is a constant search for better equipment. It is a hi-tech field where research programmes in universities can still compete (and collaborate) with industrial programmes. Its importance for society as a whole is obvious. It is very rewarding for students to see that their efforts can have a direct or indirect impact on clinical practice. We are looking forward to the coming year and the many new opportunities for students, researchers and clinicians!
Prof. Frans C.T. van der Helm
1. Introduction
Biomedical Engineering (BME) involves the application of engineering principles and technologies to medicine and biology so as to define and solve problems in these fields. The two-year MSc programme in Biomedical Engineering at Delft University of Technology started in September 2004. Although still a young programme, it is founded on a long history of teaching and research in BME within three collaborating faculties: the Faculty of Applied Sciences (Physics), the Faculty of Electrical Engineering, Mathematics and Computer Science, and the Faculty of Mechanical Engineering, Marine Technology and Materials Science.
Bundling the education and research programmes of these three faculties a broad BME programme could be realised. Additionally, the programme includes close and intensive collaboration with clinical partners at Leiden University Medical Center (LUMC), the Erasmus Medical Center Rotterdam (Erasmus MC), and the Academic Medical Center Amsterdam (AMC). Clinical partners participate in first-year MSc teaching (LUMC and Erasmus MC), and in the tutoring of MSc projects in the second year (LUMC, Erasmus MC, and AMC). Biomedical engineers have a solid technical background and additional knowledge of the medical field. In the biomedical industry, they apply their knowledge to the development and improvement of instruments for minimally invasive surgery, joint replacement prostheses, pacemakers, catheters, etc. Within the health service, in particular in academic medical centres, biomedical engineers participate in research and education. Two examples are biomechanical research focused at the improvement of joint replacement prostheses at an orthopaedic department, and image processing research for the automated detection of narrowing blood vessels at a department of cardiology. In total, six specialisations are offered within the MSc in BME programme. Three of these specialisations require a background in Mechanical Engineering; two require a background in (Applied) Physics, and one in Electrical Engineering. This means that BSc graduates in Mechanical Engineering, Applied Physics or Electrical Engineering from a University of Technology may enter the BME programme without any restrictions. TU BSc graduates holding other degrees may also enter the programme but only after completing a series of additional courses. Graduates holding a degree from a Dutch polytechnic (Technische Hogeschool) may also enter the programme upon completion of a number of additional courses: the Pre-Masters programme. Additional (BSc) courses up to 15 ECTS may be incorporated into the MSc programme. In the event that further additional courses are required these will partly come on top of the MSc programme. See chapter 6 for detailed information on enrolment.
Chapter 2 sets out the goals of the masters programme in Biomedical Engineering and chapter 3 describes the qualifications of the MSc in Biomedical Engineering graduate. In chapter 4, an overview of the study programme is given. The six specialisations are presented in more detail in chapter 5. In chapter 6, the admission programmes for academic bachelors and Dutch polytechnic bachelors graduates are described. The medical courses on offer at LUMC and the Erasmus MC and in some of the research groups in the two academic hospitals that offer final masters thesis assignments are presented in chapter 7. Chapter 8 contains an overview of biomedical and medical courses and an overview of mathematics and engineering courses. Chapters 9-12 provide further practical information.
2. Goals
The goal of the master programme in Biomedical Engineering is to educate academic engineers, who are technically high-skilled and have additional medical and biological knowledge. Graduates are capable to collaborate with clinicians, researchers and other health care professionals in order to: Identify, define and analyse biomedical problems, for the solution of which Biomedical Engineering principles and techniques can contribute Develop and to produce a sound solution to the problem Present these solutions effectively
3. Qualifications of MSc in BME graduates

Graduates of the MSc in Biomedical Engineering are suitably qualified in the following areas: 1. Broad and profound knowledge of the engineering sciences (mathematics and applied physics) and the ability to apply this at an advanced level in one biomedical engineering specialisation. 2. Broad and profound knowledge of science and technology and of the particular BME specialisation and, moreover, the skills to use this knowledge effectively in biophysical modelling of human anatomy and physiology as well as in the design of technical tools to analyse, monitor, assist and replace anatomical and physiological functions in a clinically effective, biocompatible, safe and cost-effective way. The discipline is mastered at different levels of abstraction, including a reflective understanding of its structure and relation to other fields, and reaching in part the forefront of scientific or industrial research and development. This knowledge forms the basis of innovative contributions to the discipline in the form of new designs or development of new knowledge. 3. Thorough knowledge of paradigms, methods and tools as well as the skill to actively apply this knowledge in analysis, modelling, simulating, designing and performing research with respect to innovative biomedical engineering, with an appreciation of different application areas. 4. The capacity to independently solve technological and biophysical problems in a systematic way through problem analysis, formulating sub-problems and providing innovative technical solutions, also in new and unfamiliar situations. This includes a professional attitude towards identifying and acquiring new areas of expertise, monitoring and critically evaluating existing knowledge, planning and executing research, adapting to changing circumstances, and integrating new knowledge with an appreciation of its ambiguity, incompleteness and limitations. 5. The capacity to work both independently and in multidisciplinary teams, interacting effectively with specialists and taking initiatives where necessary. 6. The capacity to effectively communicate (including presenting and reporting) details about ones work, such as solutions to problems, conclusions, knowledge and considerations, to both professionals and a non-specialist public, in the English language. 7. The capacity to evaluate and assess the technological, ethical and societal impact of ones work, and to take responsibility with regard to sustainability, economy and social welfare. 8. A commitment to independently maintaining ones professional competence through lifelong learning.
4. Study programme
Biomedical Engineering is a two year academic masters programme. There are six specialisations within the programme: Medical Instruments and Medical Safety (MIMS); BioMechatronics (BM); Tissue Biomechanics and Implants (TBI); Medical Imaging (MI); Medical Physics (MP); Biomedical Instrumentation (BI).
These specialisations cover a broad spectrum within Biomedical Engineering. Each specialisation requires its own specific background knowledge. At the beginning of the study programme students must choose their specialisation. Switching between specialisations is possible, but students should take into account the obligatory courses and additional courses required for each specialisation. This chapter gives general information on teaching periods, examinations and European Credits, followed by a presentation of the first and second year study programmes. 4.1 4.1.1 General information Semesters and periods
Each course year is divided in two semesters. Each semester consists of two periods (quarters). In this study guide, these periods will be referred to as 1A, 1B, 2A and 2B. A period consists of seven weeks of lectures, followed by two or three weeks in which examinations may be scheduled. 4.1.2 Examinations
Examinations may be oral or written. For those subjects in which written examinations are scheduled, students will have at least one opportunity per year to resit examinations (written or oral). Examinations are scheduled immediately after the period in which the course is taught. Resits generally take place after the next period. Resits for examinations taken in period 2B are scheduled in the second half of August. 4.1.3 Study load and European Credits
The study load of a course is expressed in European Credits (EC) to reflect the European Credit Transfer System (ECTS), which encourages acknowledgement of qualifications between higher education institutions in the European Union. The study load for one study year is 60 EC. Credits give an indication of the relative weights of certain parts of the course. One EC involves approximately 28 study hours. The study load includes all time spent on the course: lectures, private study, traineeship, practical assignments, examinations, etc.
The study programme involves two years of study, each with a study load of 60 EC. The total programme is worth 120 EC. 4.2 MSc: first year (60 EC)
In the first year, students are expected to take at least 30 EC in biomedical courses and at least 30 EC in fundamental technical courses. Both the biomedical courses and the fundamental technical courses have an obligatory part that is specific to each specialisation and an elective part that must be chosen in agreement with the professor responsible for the specialisation. Lists of recommended courses and other elective courses are provided for this purpose (see Tables IX, X and XI in Chapter 8). Biomedical courses are taught by engineers and clinicians. Clinicians discuss clinical issues and explain their viewpoints, whilst also covering progress in clinically-related research. There are several medical courses that can be taken within the educational programme of two of our clinical partner universities, Leiden University Medical Center and the Erasmus Medical Center Rotterdam: students may take these medical courses to a maximum of 10 EC. From the engineering viewpoint, emphasis is placed on technical and biophysical aspects, such as the latest advances in design, modelling and simulation, all the time relating this to the engineering background of the students. 4.2.1 Individual Study Programme (ISP)
All 'new' students need to register their program with selected courses using a prescribed template, which can be found on www.bme.tudelft.nl. Please check this Study Guide to ensure that your program meets the requirements, check your calendar for conflicting lecture times and to spread your study load over the year, and consult the applicable professor to ensure that you optimally prepare for your specialisation. The template needs to be signed by the applicable professor and by the student and the original signed form shall be delivered to the Master Coordinator R. Happee (CoordinatorBME@tudelft.nl) for formal registration.
4.3
MSc: second year (60 EC)
The second year starts with a traineeship in a biomedical research group or biomedical company. Bachelors graduated from a polytechnic school (TH) are exempted from this traineeship. The remainder of the year is taken up with a literature survey and a masters thesis project. The traineeship and literature survey may be undertaken in any order. In general, assignments are carried out individually. It is best if the literature survey, traineeship and masters thesis project are in the same field of research. Students shall discuss and plan the traineeship, literature survey and masters thesis project with the professor of the chosen specialisation. Some assignments and internships can be found on www.bme.tudelft.nl. 4.3.1 Traineeship in a hospital, industry or other research institute (12 EC)
Over the course of their traineeship students undertake a project task defined in consultation with the host institute. It is recommended that Dutch students undertake their traineeship abroad. The faculty overseeing the Biomedical Engineering masters programme will support student initiatives for study abroad, or will actively help in finding host institutions. Traineeships should culminate in a report. Important! Bachelors graduates with a polytechnic high school degree are exempted from the traineeship. Traineeships are usually arranged via one of the staff members in the students chosen specialisation. The Information Centre in the Student Facility Centre also holds extensive information on a large number of companies abroad and on financial matters, work permits, visas, etc. Additional information is available on their website: http://www.sfc.tudelft.nl. Students may also contact the International Exchange Coordinator: Mrs Mascha Toppenberg Room 8B-2-31, Mekelweg 2, 2628 CD Delft Tel.: +31 (0)15 27 86959, E-mail: m.p.i.toppenberg@tudelft.nl Important! Students are encouraged to contact the professor in charge of their chosen specialisation at the start of the traineeship selection process. This helps to avoid problems later on: professors have a good overview of institutes and companies within their line of work and are in a position to judge whether or not the chosen institute or company is suitable. The professor responsible must give his approval before traineeships are started. 4.3.2 Literature survey (10 EC)
It is recommended that students do their literature survey in the same research field as their masters thesis project. The literature survey will finish with a report and presentation in a seminar attended by staff and fellow students.
4.3.3
Masters thesis project (38 EC)
The masters thesis project is the final part of the BME programme. Ideally, the project is undertaken in collaboration with a clinical partner (Leiden University Medical Center (LUMC), Erasmus Medical Center (ERASMUS MC) Rotterdam, or the Academic Medical Center (AMC) Amsterdam). Regardless of whether thesis work is carried out in Delft or at the premises of the clinical partner, every MSc student will have a clinical tutor and a technical tutor. Roughly six weeks after the start of the project, students give an introductory presentation in which the project goals, methodology and the research plan are presented. Students then prepare the MSc thesis as a project report. Thesis work is evaluated by way of an oral presentation (graduation seminar) by the candidate and an oral examination before an MSc examination committee composed of at least three scientific staff members, including the thesis supervisor and one staff member from outside the research group. The examination committee may also include external examiners from research institutes or from industrial partners. 4.3.4 Oral presentations
In multidisciplinary research it is essential that students have good communication skills. Each student must therefore give three oral presentations (seminars) as part of training in delivering a clear message to a public from a different background. For each presentation a grade will be given: one for the literature seminar, one for the seminar held six weeks after the start of the masters assignment (introductory seminar), and one at the end of the masters thesis project (graduation seminar). These seminars are obligatory for all final-year Biomedical Engineering students. 4.4 Student interviews
We feel that it is essential that students know what is expected of them, and that students let us know if there are problems within the study programme, in order that we can make improvements. At the beginning of the academic year a central presentation will be given, in which new students will be given a thorough introduction to the BME programme, and where new students can meet each other. Following this presentation, and before 15 October, an individual study programme (ISP) will be drawn up in discussion with the master coordinator (see section 4.2.1). In addition to this, every student is assigned an official student interview each year to discuss study progress and for feedback on the study programme. Students complete an anonymous questionnaire, which forms the basis for action taken to improve courses. Important! Student interviews are supplementary to, but not a replacement for, regular student-professor contact held on a more informal basis.
5. Specialisations within the MSc in BME programme

Students starting the BME master programme should be aware that the programme is divided into 6 specialisations. Medical Instruments and Medical Safety (MIMS) BioMechatronics (BM) Tissue Biomechanics and Implants (TBI) Medical Imaging (MI) Medical Physics (MP) Biomedical Instrumentation (BI)
Not only do these specialisations focus on different aspects of biomedical engineering, they also require different baseline knowledge to be admitted. Important! At the beginning of the study programme students must choose their specialisation. Switching between specialisations is possible, but students should take into account the obligatory courses and additional courses required for each specialisation. Chapter 5 describes the main focus of education and research in each specialisation and Chapter 6 describes admission requirements and specific deficiency programmes for the specialisations.
5.1
Medical Instruments & Medical Safety (MIMS)
Professor in charge: Prof. Jenny Dankelman Tel: +31 (0)15 27 85763 E-mail: j.dankelman@tudelft.nl Prof. Peter A Wieringa, Prof. Cees A Grimbergen Medical Instruments Group, Dept of Biomechanical Engineering, Faculty of Mechanical, Maritime and Materials Engineering (3ME). 5.1.1 Overview
The goal of research within the Medical Instruments & Medical Safety specialisation is to develop new devices, processes and systems aimed at improving the quality and safety of health care delivery. Medical instrument development is focused in several medical disciplines, including minimally invasive surgery, colonoscopy, and catheter interventions. To operate through small incisions in the skin, surgeons require special instruments, making minimally invasive techniques a challenging field of application. New flexible instruments are being developed for use in minimally invasive surgery. In the field of colonoscopy a new locomotion system has been developed to move more easily through the bowel and lessen patient pain. Medical instrument research also focuses on the quality of medical instruments and their optimal use, maintenance and sterilisation. New training equipment such as virtual reality trainers and simulators with force/haptic feedback is being developed to train surgeons outside the operating theatre. This specialisation is directed at the medical specialisations surgery, cardiovascular diseases and gastroenterology. 5.1.2 Admission
BSc graduates in Mechanical or Biomedical Engineering may be admitted to this specialisation without the need to take additional courses. Bachelor graduates with other degrees must attend additional courses. More information can be found in Table I.
5.2
Biomechatronics (BM)
Professor in charge: Prof. Frans C T van der Helm Tel: +31 (0)15 27 85616 E-mail: f.c.t.vanderhelm@tudelft.nl Biomechatronics & Biorobotics group, Dept of Biomechanical Engineering, Faculty of Mechanical, Maritime and Materials Engineering (3ME) 5.2.1 Overview
Biomechatronics is the interdisciplinary study of biology, mechanics and electronics. It focuses on the research and design of assistive and diagnostic devices for patients with disorders of the neuromuscular-skeletal system. A thorough knowledge of the healthy system is required, in addition to knowledge about patient status, i.e. the causes and symptoms of disease. In particular, biophysical models of muscles, joints, the Central Nervous System and sensors, and human motion control are very helpful for analysis and innovative designs. The interactivity of biological organs (including the brain) with electromechanical devices and systems is an important feature. In this specialisation the main focus is on prosthetics, orthotics, joint implants, diagnostic devices for neurological disorders, neuro-rehabilitation robots, and haptic interfaces, etc. Other exciting biomechatronic opportunities that scientists foresee in the near future include electronic stimulators of muscles and nerves for stroke victims and patients with trauma to the Central Nervous System. 5.2.2 Admission
BSc graduates in Mechanical or Biomedical Engineering may be admitted to this specialisation without the need to take additional courses. Bachelor graduates with other degrees must attend additional courses. More information can be found in Table I.
5.3
Tissue Biomechanics and Implants (TBI)
Professor in charge: Prof. Fred van Keulen Tel: +31 (0)15 27 86515 E-mail: f.vankeulen@tudelft.nl Precision and Microsystems Engineering, Faculty of Mechanical, Maritime and Materials Engineering (3ME) 5.3.1 Overview
Despite the fact that joint replacement prostheses have been around since the 1960s, they still have a long way to go before they achieve perfection. Very good results have been achieved using hip prostheses, but prostheses for shoulder joints and fingers, for example, fail frequently. To improve these prostheses, close cooperation between the medical and technical professions is essential. In this masters programme students will become acquainted with skeletal tissues (bone, cartilage and tendons), joint anatomy, and methods for measuring and calculating stresses and strains in bone as well as in prostheses and materials that can be used in the human body, which must be both biocompatible and durable. The biomechanical properties of skeletal tissues will be explored: how strong are these materials, andperhaps more importantlyhow do these tissues change with ageing and disease, and how does tissue react when a prosthesis is implanted? Bone is a living tissue that is able to adapt its mass and architecture to changes in external loads: astronauts lose bone in space, while tennis players have a larger bone mass in their dominant arm. Via the same adaptation mechanism, changes in the loading of the bone caused by implantation of a prosthesis will induce changes in bone mass. In developing prostheses, scientists must try to predict these changes and take advantage of the adaptive capability of the skeleton. In order to do this, mechanical tests and advanced computer models must be combined. At the end of this specialisation students will be able to combine technical and biomedical knowledge in order to make a valuable contribution to new developments in the field of orthopaedics. 5.3.2 Admission
BSc graduates in Mechanical Engineering may be admitted to this specialisation without the need to take additional courses. Bachelor graduates with other degrees must attend additional courses. More information can be found in Table II.
5.4
Medical Imaging (MI)
Professor in charge: Prof. Wiro Niessen E-mail: w.niessen@erasmusmc.nl, Tel: +31 (0)10-7043050 Primary Contact: Dr Frans Vos; E-mail: F.M.Vos@tudelft.nl, Tel: +31 (0)15 27 87133 Prof. Lucas van Vliet; E-mail: L.J.vanVliet@tudelft.nl, Tel: +31 (0)15 27 87989 Quantitative Imaging Group, Faculty of Applied Sciences Secretary: M.S.M. Jungschlager; E-mail: M.S.M.Jungschlager@tudelft.nl, Tel: +31 (0)15 27 81416 IST/Quantitative Imaging (room F240) 5.4.1 Overview
Imaging plays an increasingly important role in modern medicine. Nowadays, imaging methods such as Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and diagnostic ultrasound provide high-quality three-dimensional and even four-dimensional pictures not only of the human anatomy, but also of its function and its changes over time, aspects that are very much characteristic of the medical field. The high quality of these pictures must be balanced against human factors such as acquisition time and radiation burden for the patient. The task of the MSc in this specialisation is to provide user interface and visualisation facilities for the many Terabytes of data that are produced yearly in a hospital. It is even more important to provide quantitative, accurate and consistent measurements of the objects of interest in the images, in order to complement the qualitative judgment of the radiologist or other medical specialist. Where images have been acquired using different imaging methods, or at different moments, it is necessary to match or register individual images before they can be merged or subtracted from each other. Intelligent utilisation of measurements can aid interpretation and classification of the image content, which in turn can provide important diagnosis support. As in every MSc in Biomedical Engineering, graduates of this specialisation must show competence in cooperating with medical specialists, giving frequent feedback on problems in hand as well as on proposed solutions. Professional opportunities lie in medical research, clinical support, and with suppliers and manufacturers of the various devices for acquisition and processing of medical images, mainly in the field of radiology. 5.4.2 Admission
BSc graduates in Applied Physics may be admitted to this specialisation without the need to take additional courses. Bachelor graduates with other degrees must attend additional courses. More information can be found in Table III.
5.5
Medical Physics (MP)
Professor in charge: Prof. Freek Beekman Tel. +31 (0)15 278 6560, E-mail: F.J.Beekman@tudelft.nl Primary Contact: Dr J Zoetelief Tel: +31 (0)15 2786777, E-mail: J.Zoetelief@tudelft.nl Prof. H Th Wolterbeek Department of Radiation, Radionuclides and reactors (R3), Faculty of Applied Sciences 5.5.1 Overview
Medical Physics is a specialisation that has undergone extensive development in recent years. On one hand this is due to the ever-increasing application of physical methods in health care; on the other hand it appears that medical physicists are valuable partners in the discussion between the various professionals working at health care institutions. Medical physicists are responsible for the standardisation and calibration of medical instruments, in close cooperation with medical and paramedical professionals. Furthermore, they are responsible for the accuracy and safety of physical methods applied in hospitals for diagnosis and therapy. The medical physicist often has a commanding position with respect to investments in medical equipment, and medical professionals and hospital management rely heavily upon their judgement. Topics can be divided into five areas of interest: general medical physics, radiotherapy, radiology, and nuclear medicine. In radiotherapy, clinical physicists play a major role in treatment planning. Medical physicists are often involved in research projects. In the first year the MSc programme consists of approximately 50% medical technology and related classes and about 50% fundamental technical classes. In the classes on medical physics and radiation technology, in which medical imaging and radiotherapy is covered, medical aspects are presented by hospital professionals. In the second year of the MSc programme students undertake a thesis project. This will, in general, be carried out at a hospital and be tutored by a staff member at Delft University of Technology and a staff member from the hospital. The Biomedical MSc specialisation Medical Physics qualifies for admission to the selection procedure for the in-service post-doctoral education on clinical physics (Klinische Fysica). This qualification has been recognised by the Dutch Society for Medical Physics (Nederlandse Vereniging voor Klinische Fysica, NVKF www.nvkf.nl). 5.5.2 Admission
BSc graduates with an academic degree in Applied Physics may be admitted to this specialisation without the need to take additional courses. Bachelor graduates with other degrees must attend additional courses. More information can be found in Table III.
5.6
Biomedical Instrumentation (BI)
Professor in charge: Prof. Paddy French Tel: +31 (0)15 27 84729 E-mail: p.j.french@tudelft.nl Electronic Instrumentation Laboratory, Faculty of Electrical Engineering, Mathematics and Computer Science 5.6.1 Overview
Within the Department of Microelectronics, biomedical research activities are directed towards sensor microsystems in the Laboratory for Electronic Instrumentation and low-voltage, low-power electronics in the Laboratory for Electronics. The mission in the Laboratory for Electronic Instrumentation is to develop smart microsystems for biomedical measurements (both in vivo and in vitro) and implants. These projects bring together sensing devices and read-out electronics. In recent years the laboratory has been developing a catheter navigation system, multi-sensors for catheters (including measurements in blood), microsystems for monitoring cardiac output, a blood impedance measurement system, polymerised chain reaction (PCR) chips, streaming potential in bone, blood analysis and drain fluid analysis. These projects have been performed in collaboration with a number of hospitals and biochemical and medical companies. In this specialisation, electronic design methodologies and proof-of-concept vehicles for low-power adaptive integrated circuits for biomedical wearable, implantable and injectable devices are being developed. These are battery powered or battery-less biomedical electronic devices, such as hearing aids, cochlear implants, neurostimulators, pacemakers, and wireless links for biomedical sensors used in health monitoring and telemedicine applications. Major design constraints that are taken into account are reliability, low voltage (0.73V) and ultra low power (<< 1MW) operation. 5.6.2 Admission
BSc graduates with an academic degree in Electrical Engineering may be admitted to this specialisation without the need to take additional courses. Bachelor graduates with other degrees must attend additional courses. More information can be found in section 6.2.5.
5.7
Annotation Entrepreneurship
Students may include additional courses on Entrepreneurship in their program and select a Masters Assignment with Entrepreneurial aspects. The Entrepreneurship annotation will be mentioned on the MSc degree (see www.dce.tudelft.nl / contact m.a.vanveelen@tudelft.nl). Conditions and courses will be similar to those for the Entrepreneurship programme within the Master Mechanical Engineering.
6. Admission
The content of the bachelors degree and results will be evaluated for each candidate. The intake coordinator on the examination committee is responsible for this selection. The admissions procedure may result in one of the following: Admission without additional requirements. Admission with additional requirements of no more than 15 EC. The additional bachelors courses may be regarded (and counted) as elective courses for the chosen specialisation in the masters programme. Admission with additional requirements between 15 and 45 EC. In this instance at most 15 EC of the additional bachelors courses may be regarded (and counted) as elective courses for the chosen specialisation in the masters programme and further required additional bachelors courses will be on top of the standard 120 EC MSc programme. No admission (additional requirements are more than 45 EC). The candidate must obtain a relevant bachelors degree first. 6.1 Admission for students with an academic bachelors degree
Students with a Dutch academic Bachelors degree in Biomedical Engineering, Applied Physics, Mechanical Engineering, Aerospace Engineering, Electrical Engineering, Marine Technology, Industrial Design Engineering, Civil Engineering or Chemical Engineering from a Dutch university of technology or a Bachelors degree in Physics from a Dutch university are eligible for admission to the programme.
International applicants with a Bachelors degree from an IDEA League University (ETH Zrich,
Imperial College London, Technische Universitt Aachen or ParisTech - Grandes Ecoles d'Ingenieurs de Paris) in Biomedical Engineering, (Applied) Physics, Mechanical Engineering, Aerospace Engineering or Electrical Engineering are eligible for admission to the programme. Others are admitted on a case by case basis. Students choosing a specialisation which does not ideally match their Bachelor degree need to take some additional bachelors courses in order to be admitted to a specific specialisation. Depending on the specialisation these courses will be in the Mechanical Engineering, Applied Physics or Electrical Engineering field.
6.1.1 Additional Bachelors courses for admission to Medical Instruments and Medical Safety (MIMS) and Biomechatronics (BM) The schakelminor Mechanical Engineering provides direct access. Table I: Overview of additional Bachelors courses required for admission to the specialisations Medical instruments and Medical Safety (MIMS) and Biomechatronics (BM). Numbers indicate EC points.
Course Code WB1216-06 WB1217 WB2207-07 WB3110 WB3250 WBTP211 WI2252wbmt Course Name Dynamics 2 Sterkteleer 2 (Strength of Materials 2) Regeltechniek (Systems & Control Eng) not required for students that completed AE3-359 Evolving Design (3EC) Signal Analysis (3EC) Mechatronics Analysis 3 not required for students that completed WI2145ID Total EC BE AP ME EE AE MT IDE CI CE 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 # # @ 10 10 3 22* 19 0 # @ 10 10 (3) 16 3 13 12 16 19 10 10 # #
BE = Bachelor in Biomedical Engineering; AP = Bachelor in (Applied) Physics; ME = Bachelor in Mechanical Engineering; EE = Bachelor in Electrical Engineering; AE = Bachelor in Aerospace Engineering; MT = Bachelor in Marine Technology; IDE = Bachelor in Industrial Design Engineering; CI = Bachelor in Civil Engineering; CE = Bachelor in Chemical Engineering. # WB3110 is recommended for students with an interest in mechanism design @ WB3250 signal analysis is useful for students lacking a basis in this field and planning to follow the Master course WB2301 System identification & parameter estimation * Bachelors in Biomedical Engineering or Technische Geneeskunde may get dispensation on some of these courses as well as some Master courses
6.1.2 Additional Bachelors Courses for admission to Tissue Biomechanics and Implants (TBI) The schakelminor Mechanical Engineering provides direct access. Table II: Overview of additional Bachelors Courses required for admission to the specialisations Tissue Biomechanics and Implants (TBI). Numbers indicate EC points.
Course Code WB1216-06 WB1217 WB1218-07 WB2207-07 Course Name BE AP ME EE AE MT IDE CI Dynamics 2 3 3 3 3 3 Sterkteleer 2 (Strength of Materials 2) 3 3 3 3 Non Linear Mechanics 2 2 2 2 Regeltechniek (Systems & Control Eng) not 3 3 3 3 3 3 required for students that completed AE3-359 WBTP211 Mechatronics WI2051wbmt Differential Equations 3 3 WI2252wbmt Analysis 3 not required for students that 3 (3) completed WI2145ID Total EC 17* 11 0 8 3 3 17 6 BE = Bachelor in Biomedical Engineering; AP = Bachelor in (A)pplied Physics; ME = Bachelor in Mechanical Engineering; EE = Bachelor in Electrical Engineering; AE = Bachelor in Aerospace Engineering; MT = Bachelor in Marine Technology; IDE = Bachelor in Industrial Design Engineering; CI = Bachelor in Civil Engineering; CE = Bachelor in Chemical Engineering. * Bachelors in Biomedical Engineering or Technische Geneeskunde may get dispensation on some of these courses as well as some Master courses CE 3 3 3
6.1.3 Additional Bachelors Courses for admission to Medical Imaging (MI) and Medical Physics (MP) The schakelminor Applied Physics provides direct access. Table IIIA: Overview of additional Bachelors Courses required for admission to the specialisation Medical Imaging (MI). Numbers indicate EC points.
Course Code TN1612TU TN2053 TN2344 TN2545 Course Name AP ME EE AE AM CS CE Mechanics and theory of relativity 6 6 6 6 Electromagnetism 1 6 6 6 6 6 Waves 6 6 6 6 6 6 Systems and signals 6 6 6 6 Total EC 0 18 12 18 18 22 22 AP = Bachelor in (Applied) Physics; ME = Bachelor in Mechanical Engineering; EE = Bachelor in Electrical Engineering; AE = Bachelor in Aerospace Engineering; AM = Bachelor in Applied Mathematics; CS = Bachelor in Mathematics in Computer Sciences; CE = Bachelor in Chemical Engineering.
Table IIIB: Overview of additional Bachelors Courses required for admission to the specialisation Medical physics (MP). Numbers indicate EC points.
Course Code TN1612TU TN2053 TN22111 TN2344 TN2311+TN2411 (or TN2301) TN2545 TN2622 TN2785 TN2843 TN2951-p1 Course Name Mechanics and theory of relativity Electromagnetism 1 Electronic instrumentation Waves Quantum mechanics AP ME 6 6 6 6 EE 6 AE 6 6 6 6 AM 6 6 6 6 6 CE 6 6 6 6 6
6 6
Systems and signals 6 Statistical physics 4 4 4 4 4 Physical transport phenomena 6 6 Solid state physics 5 5 5 5 5 Research laboratory (1 experiment 6 6 6 6 6 from each department) Total EC 0 39 39 39 51 51 AP = Bachelor in (Applied) Physics; ME = Bachelor in Mechanical Engineering; EE = Bachelor in Electrical Engineering; AE = Bachelor in Aerospace Engineering; AM = Bachelor in Applied Mathematics; CE = Bachelor in Chemical Engineering.
1
Students should register in advance at Practicum Administration room A001 in the TN building
6.1.4
Additional Bachelors Courses for admission to Biomedical Instruments (BI)
This specialisation is recommended for students with a Bachelor in Electrical Engineering, who can be admitted directly. The schakelminor Electrical Engineering for the Constructing Sciences also provides direct access. Students with degrees such as Applied Physics should show that they have at least 13 EC in Electrical Engineering courses in their Bachelor curriculum. Students who do not meet the admission requirements, in terms of courses followed, may be required to attend additional courses. This can be arranged on an individual basis.
6.2
Admission for students with a bachelors degree from a Dutch polytechnic school
(TH/HBO) 6.2.1 Introduction
Candidates with a Dutch HBO Bachelors in Electrical Engineering, Mechanical Engineering, Applied Mathematics, Applied Physics, Aerospace Engineering or Human Motion Technology are eligible for admission. The candidate must have completed the Bachelors programme within 4 years with good results. The intake coordinator on the Examination Committee is responsible for the selection of candidates. An additional pre-masters programme of approximately 30 EC must be completed before candidates are formally admitted to the MSc programme. In the pre-masters programme, a number of courses from the second year of the academic bachelors programme must be followed. These additional requirements will ensure that students have an entrance level at least comparable to that of the second course year of the academic bachelors programme that forms the basis for the specific specialisation, i.e. Mechanical Engineering for MIMS, BM and TBI; Applied Physics for MI and MP, and Electrical Engineering for BI. The person in charge of the chosen specialisation may also require that a number of third-year courses from the bachelors programme are followed. Important! All courses in the pre-masters programme are taught in Dutch. Candidates are formally admitted only to the pre-masters programme. However, both the pre-masters programme and MSc courses can be followed in the first MSc year. Students are formally admitted to the MSc programme after completing the pre-masters programme. The proposed pre-masters programme must be approved by the Examination Committee. As explained above, it is important to note that the pre-masters programme gives admission to specific specialisations within the BME MSc programme. This means that students must choose their specialisation at the start of their BME study. The total number of EC points for courses in the MSc programmeincluding the pre-masters programmefor bachelors students from a polytechnic school is approximately 80 to 90 EC. This is 20 to 30 EC more than academic bachelors graduates not undertaking a pre-masters programme. The period over which courses are attended is about one and a half years. Polytechnic bachelors graduates must plan their courses well in advance. Unfortunately, it is almost impossible to avoid interference between bachelors courses in the pre-masters programme and the MSc courses. Therefore, we recommend that polytechnic students contact the BME MSc programme coordinator in their first or second week of study at TU Delft at BME-coordinator@tudelft.nl.
6.2.2 Pre-masters programme for Medical Instruments and Medical Safety (MIMS); Biomechatronics (BM); and Tissue Biomechanics and Implants (TBI) In these three specialisations, bachelor graduates with a TH degree in Mechanical Engineering, Aerospace Engineering or Human Motion Technology (Bewegingstechnologie) may enrol after they have followed a pre-masters programme of courses that will give them the same level of knowledge as an academic BSc graduate in Mechanical Engineering. Therefore, this pre-masters programme is almost the same as the pre-masters programme for the MSc in Mechanical Engineering. This programme totals an additional 26 EC. However, because these students are not required to undertake a traineeship during the MSc phase, the total additional study load compared to academic bachelor graduates is 14 EC. Advice on this pre-masters programme can be obtained from one of the study advisors at the Faculty of Mechanical Engineering, Evert Vixseboxse, at E.Vixseboxse@tudelft.nl. Table IV: Mechanical Engineering pre-masters programme.
Code WB1216-06 1) WB1217 1) WB1218-07 1) WB2207-07 1) WI1708th1 WI1708th2 WI1708th3 WI1807th1 WI1909th Course name EC Dynamica 2 3 Sterkteleer 2 3 Niet lineaire mechanica 2 Regeltechniek 3 Analyse 1 TH 3 Analyse 2 TH 3 Analyse 3 TH 3 Lineaire algebra 1 TH 3 Differential Equations 3 Total 26 1) Students are encouraged to prepare for some of the second-year bachelors courses by careful reading of material from the corresponding first-year courses: wb1115 Sterkteleer 1, wb1116 Dynamica A, and wb2104 Introductie Modelvorming en Regeltechniek 1. Lecture hours 0/0/0/4 0/3/0/0 0/0/3/0 4/0/0/0 4/0/0/0 or 0/0/4/0 0/4/0/0 or 0/0/0/4 4/0/0/0 or 0/0/4/0 4/0/0/0 or 0/0/4/0
6.2.3
Pre-masters programme for Medical Imaging (MI) and Medical Physics (MP)
In these two specialisations, bachelors graduates with a TH degree in Applied Physics may enrol after they have followed a pre-masters programme of courses that will give them the same level of knowledge as an academic BSc graduate in Applied Physics. Therefore, this pre-masters programme is similar to the pre-masters programme for Applied Physics. This programme totals an additional 28 EC for MI and 40 EC for MP. However, because these students are not required to undertake a traineeship during the MSc phase, the total additional study load compared to academic bachelors graduates is 16 EC for MI and 28 EC for MP. Advice on this pre-masters programme can be obtained from the polytechnic study advisor at the Faculty of Applied Sciences, Mrs Maricha Reedijk, at m.reedijk@tudelft.nl. More detailed information can be found in the MSc in Applied Physics student handbook. Table V: Applied Physics pre-masters programme.
Code TN2053 TN2311+TN2411 (or TN2301) TN2344 TN2545 TN2951-P WI1142TN + WI2242TN WI2140TN Course name Electromagnetism I Quantum mechanics Waves Systems and signals Research Practicum voor Schakelprogramma AP Linear algebra Differential equations Total Medical Imaging (MI) EC 6 Medical Physics (MP) EC 6 6 6 6 6 6 4 40
6 6 6 4 28
6.2.4
Pre-masters programme for Biomedical Instruments (BI)
In this specialisation, students with a polytechnic bachelors degree in Electrical Engineering may enrol after they have followed a pre-masters programme of courses that will give them the same level of knowledge as an academic BSc graduate in Electrical Engineering. This pre-masters programme is exactly the same as the pre-masters (or bridging) programme for Electrical Engineering track Microelectronics. For further information E-mail: studieadviseurs@ewi.tudelft.nl. Part of the pre-masters programme is filled in on an individual basis. Therefore, it is essential that students make an appointment with Prof. Paddy French at the start of the year (p.j.french@tudelft.nl). Prof. French can also provide students with any information missing in Table VI. Table VI: Electrical Engineering pre-masters programme
Code ET2505-A ET8027 ET8028 ET8040 ET8041 SC2030ET WI1000 WI1708TH1 WI1708TH2 WI1708TH3 WI1807TH1 WI1807TH2 Total Course name Stochastic Processes Solid State Physics Analog Electronic Circuits Signaaltransformaties HBO EM-golven HBO Dynamic Control Systems Refresher Track Analysis 1 Analysis 2 Analysis 3 Linear Algebra 1 Linear Algebra 2 EC 3 3 2 5 4 8 0 3 3 3 3 3 40
Students will gain access to the Masters degree programme if they have their HTO diploma and if they earned a mark greater than or equal to 6 for a set of study units that add up to at least 30 EC and include at least WI1000, WI1708TH1, WI1708TH2, WI1708TH3, WI1807TH1 and WI1807TH2. The study units of the bridging programme that are not included in this set of 30 EC may be part of the MSc programme and will be considered homologation courses in the free elective space, which is restricted to 15 EC. However, because these students are not required to undertake a traineeship during the MSc phase, the total additional study load compared to academic bachelors graduates is about 20 EC. More detailed information can be found in the MSc study guide for Electrical Engineering.
6.3
Admission for students still in their academic bachelors programme
Students who have not yet finished their bachelors programme are permitted to sit examinations in the MSc programme with the approval of the examination committee. When a student has passed the propaedeutic examination and has gained a result of at least 100 EC from their second and third years, including the bachelors project, they can be conditionally admitted to the MSc programme to sit examinations for a few MSc courses. Formal admittance is granted upon completion of the bachelors programme.
7. Teaching in Leiden (LUMC) and Rotterdam (Erasmus MC)

Part of the masters programme can be taken at Leiden University Medical Center or the Erasmus Medical Center (Rotterdam). Students have numerous opportunities to do their internship or masters thesis assignment at one of these two medical centres; and they may also take biomedical courses as listed in Table X. Summaries of these courses can be found at www.studiegids.tudelft.nl. In Leiden, the focus is on courses for the first year of the masters. In Rotterdam the focus is on courses in the second year of the masters; although the courses can be taken separately in the first year of the masters, they are also integrated into a traineeship programme that is offered to students. Students may choose medical courses at LUMC and Erasmus MC to a total of no more than 10 EC. Any additional EC points will come on top of the total of 120 EC needed to accomplish the MSc BME programme. 7.1 Courses in Leiden
Leiden University Medical Center offers several courses to Biomedical Engineering students. These 3 to 4 week courses will be followed alongside (bio)medical students to encourage interaction between future colleagues. The schedule of courses taught at LUMC is optimised for Leiden students. Therefore, these courses can and will have an overlap with Delft courses and sometimes even with the Delft examination period. Students should ensure that they check carefully that attending a fulltime course in Leiden will not interfere too much with the rest of their study programme. At LUMC, teaching is based on "doelstellingengestuurd" learning. The courses offer lectures (overview, patient demonstration, or response), workgroups, and practicals. Self study is guided by a course book that includes self-study-assignments. In workgroups, material is discussed in more detail under the guidance of a tutor. Each course is examined by a 3-hour written examination. Detailed information on the courses and their time schedule can be found at http://www.lumc.nl/onderwijs.html. The latest admission procedures for TU Delft students can be found at TU Delft Blackboard > Organisation BME > Announcements. Students must register for courses at least 6 weeks in advance, however, it is appreciated if students can make their choice right at the beginning of the academic year. Each course has its own module on the LUMC blackboard, through which the course-coordinator communicates with students. Students who have been granted admission to the courses will get access to the LUMC blackboard environment.
7.2
Courses in Rotterdam
Technology modules of 1-2 EC are offered each covering an essential technological aspect of medical research (BM1080R-BM1150R, see Table X). These courses can be followed throughout the year. Students are expected to propose when they want to take the course and register at least 4 weeks in advance. You can register for these courses by sending an e-mail to the contact person mentioned in the TU Delft Coursebase description. Medical course A general medical course (7 EC, BM1141R) on Disorders of Environment & Interior is taught each year at the Erasmus University in the first semester and covers the anatomy and physiology of selected organ systems (e.g. lung, kidney and bladder). Since this course is also part of the general medical training program it encourages interaction with medical students/colleagues.
8. All BME masters courses

BME students select their masters courses from Tables IX, X, XI. For each specialisation, there are: Obligatory courses, Recommended courses which are particularly suited to the specialisation, Elective courses that may be selected when desired.
There are many more courses at TU Delft that students may include in their study programme than those listed in Table XI: there are simply too many TU courses to fit in one table. Furthermore students may select Master courses from other Universities in and outside the Netherlands. Students wishing to take courses that are not listed should speak to the professor in charge of their specialisation. Important! Students need to select at least 30 EC Biomedical courses in total from Table IX and X. Students may select medical courses at LUMC and the Erasmus MC worth a total of no more than 10 EC. Any additional EC points will come on top of the total of 120 EC needed to complete the MSc BME programme. Students need to select at least 30 EC Mathematics and Engineering courses from Table XI.
8.1
Biomedical courses
Table IX: BME courses at TU Delft O = Obligatory; R = Recommended; E = Elective;

Course Code Course name AP3231TU D AP3361TU AP3581TU NS3511TU ET4127 ET4130 ET4363 ET4364-08 WM0811ET ID4010 IN4015 MS4232-09 WB2308 WB2407 WB2408 ME1610 BM1100 WB2432 WB2435-03 WB2436-05 WB5500 Biomedical Engineering courses Lecture EC MIMS BM hours Medical Imaging 0/0/2/2 6 R R Medical physics and radiation 0/0/2/2 6 technology Imaging Medical physics and radiation 0/0/2/2 6 technology Radiotherapy Biophysics (LST / Nanoscience) 2/2/0/0 6 Themes in biomedical Engineering 0/0/0/3 4 Bio-electricity 3/0/0/0 3 E E Medical Technology I (Diagnostic 3/2/0/0 5 O O devices) & Health Care Systems 0/0/2/0 2* Medical Technology II (TheraR R peutical devices) To be followed in conjunction with WM0811ET: Quality Assurance & Risk Analysis 0/0/4/0 2* R R Practical Design theory and methodology 3/0/0/0 3 E Neural Networks 0/0/2/2 6 E Biomaterials (formerly 4 EC) 0/0/4/2 6 R R Biomedical engineering design 0/2/0/0 4 O O Human movement control 2/2/0/0 4 R O Physiological systems 0/4/0/0 3 O O Bone and Cartilage 2/0/0/0 3 E R Orthopaedic implants and 0/4/0/0 3 E E Technology Biomechatronics 0/0/2/2 4 R O Surgical instruments and medical 3/0/0/0 2 O R safety Bio-inspired design 0/0/4/0 3 R R Biological Fluid Dynamics 0/0/0/4 3 Total obligatory courses (EC) 14 20 TBI R MI O E E E E O R R O E R O O O R R E O 23 E R O R R E E O E E E R O R R E E E O E E E E MP R O O E R O O R R E E O E E BI R E
* The combined courses ET4364 & WM0811ET represent 4EC
14
20
E 11
Table X: BME and medical courses at LUMC (see section 7.1) and Erasmus MC (see section 7.2). You can take at most 10 EC points of these electives. Timely registration is required and availability cannot be guaranteed. See announcements on the TU Delft blackboard for Biomedical Engineering for details. R = Recommended; E = Elective
Courses at LUMC and Course Course name Lecture hours code TUD Leiden BM1020L G1Zn: Zenuwstelsel 23 Nov tm 18 Dec 2009 Leiden BM1030L B2IN: Introduction 22 Feb tm into Neurosciences 19 Mar 2010 Leiden BM1050L BB311: Tools of the 24 Sep tm 9 Century 2 - Medical Oct 2009 Imaging Technology Leiden BM1060L G2HB: Houding en 15 Mar tm 2 Apr 2009 Beweging Leiden BM1070L G1SR: Sturing en 15 Mar tm 2 Apr 2009 Regeling 25 Jan tm Leiden BM1080L B2BS: Design and Analysis of 19 Feb 2010 Biomedical Studies (DABS) Statistical research methods Leiden BM1085L G3Bk: Buik 28 Sep tm 6 Nov 2009 Leiden BM1086L Surgery for start any Engineers - New time# Rotterdam BM1080R Kvr1: Tissue start any engineering time# Rotterdam BM1090R Kvr2: CT imaging in start any research and in the time# clinic Rotterdam BM1100R Kvr3: Echography start any time# Univ. Rotterdam BM1110R Kvr4: Radiotherapy imaging and physics Rotterdam BM1130R Kvr6: Strabismus surgery Rotterdam BM1141R Kvr7: General Course on Disorders of Environment & Interior Rotterdam BM1150R Kvr8: Biomedical * Image Processing start any time# start any time# Sept. - Oct. 2008 start any time# Erasmus MC EC MI BM TBI MI MS 5 E R E E 6 4 4 4 6 E E E R R R E R R R E E R E E E E E E E MP E E E E R E BI R E E E R E Language Dutch Dutch English Dutch Dutch Dutch
7 2? 1 1 1 1 2 7
R R E E E E R E
E E E E E E R E
E E R E E E E E
E E R R R R E E
E E E E R E E E
E E E E E E E E
Dutch English on request English on request English on request English on request English on request English on request Dutch
Note
BM1150R is recommended in combination with et4283 Advanced digital image processing; BM1150R is extended with new content from 1 to 2 ECTS as of September 2009 These medical courses are not taken into account when applying for the postinitial education programme for Clinical Physicist.
English on request
8.2
Mathematics and Engineering courses
Table XI: Mathematics and engineering courses at TU Delft O = obligatory; R = recommended; E = elective;
Mathematics and Engineering Lecture hours AP3081TU G International Masters Course on x/x/x/x Computational Physics AP3121D Imaging systems (optics) 2/2/0/0 0/0/2/2 AP3131 D Advanced Signal Analysis and Processing - no course in or after 2009/2010 AP3241TU D Particle Therapy Holland PTC 0/0/2/2 General & technical Aspects AP3371TU D Radiological health physics (+31 0/0/x/x hours pract.) friday AP3351D Radiation technology and radiation 2/2/0/0 detection AP3531 Acoustical imaging 0/0/2/2 CT5142 Comp. methods in non-linear 0/0/0/4 mechanics ET4248 Introduction to micro electronics 3/0/0/0 ET4252 Analogue IC design 0/3/0/0 ET4257 Silicon sensors 0/3/0/0 ET4258 Displays & actuators 3/0/0/0 ET4283 Advanced Digital Image Processing 4/4/0/0 ET4289 Integrated Circuits and MEMS 0/0/0/3 Technology ET4295 Introduction to Analog CMOS Design 2/2/0/0 ET8016 Structured electronic design 0/4/0/0 ET8017 Electronic instrumentation 1 3/0/0/0 IN4320 Machine learning (requires IN4085) 0/0/2/2 IN4085 Pattern recognition 2/2/0/0 IN4086 Data visualization 0/4/0/0 IN4307 Medical visualization 0/0/4/x ME1110 Medical Device Prototyping (limited 0/0/2/2 capacity) SC4026 4/0/0/0 Control System Design (3EC) Course code Course name
or the more extensive new course: SC4025 Control Theory (6EC) or the courses SC4020 or SC4022 given up to 2008
courses EC MIMS BM 6 6 6 6 6 6 6 3 3 4 4 4 6 4 4 5 5 5 6 6 5 6 3
TBI
MI E E E E
MP E E
BI
R O O R
R O O E O R O R R O R O E E R R E O O R R R R E
E R
E O E E
WB2301 WB2303-08 WB2404 WB1413-04 WB2414-09 WB1451-05 WB5414-08 WBP202 WI4014TU
System identification & parameter estimation Measurement in engineering Man-machine systems Multibody dynamics B Mechatronic System Design Engineering mechanics fundamentals Design of machines and mechanisms Haptic system design
0/0/2/2 0/0/2/2 0/4/0/0 0/0/2/2 2/2/0/0 0/0/2/2 2/2/0/0

0/2/0/0 or 0/0/0/2
7 3 4 4 4 4 4 4 6
O E O R E R O 15 14 29
O E R O E E R 14 20 34
R E O R O
Numerical analysis C2 x/x/0/0 Total obligatory courses (EC) this Table Total obligatory courses (EC) Table IX Total obligatory courses (EC)
R 11 23 34
18 14 32
12 20 32
16 11 27
9. Study and traineeship abroad

Study abroad offers a wealth of attractive prospects. Students become acquainted with a different (organisational) culture, university life and educational system. In addition to enlarging their personal network, students learn to live within a foreign environment, and improve their language skills. To put it briefly, a period of study abroad will make a valuable contribution to any students personal education and will pay dividends in the search for a job. Students wishing to study at a foreign university may make use of one of the many exchange agreements held with European and non-European universities. Under the terms of these agreements students do not pay tuition fees to the foreign university. Grants are also available to help finance the added cost of staying abroad. Extensive information on studying abroad is available from Back Office International Programmes at the Student Facility Centre, including information on all universities with which an exchange agreement exists, financing study abroad, and student travel reports. Further information is available on www.studyat.tudelft.nl. Internships abroad are highly encouraged and your professor / supervisor may help to arrange. Students may, with prior approval of the professor in charge of their specialisation, select master courses at other (foreign) universities as part of their study program. If you have a clear idea about where you would like to go, you should seek the advice of the International Exchange Coordinator about your programme at the foreign university and the recognition of your results at the host university. Your graduation professor will assess your work on your return according to the guidelines you agreed upon prior to departure. The foreign programme should contribute 12 EC to your MSc programme. Studying abroad requires a lot of personal preparation. Students should account for a preparation period of preferably one year, but at least half a year. Students may also contact the International Exchange Coordinator: Mrs Mascha Toppenberg Room 8B ground Floor Mekelweg 2, 2628 CD Delft Tel: +31 (0)15 27 86959 Fax: +31 (0)15 27 88340 E-mail: m.p.i.toppenberg@tudelft.nl
10. Enrolling for courses and tests, pass rules

The latest information can be found at http://www.studenten.tudelft.nl under 3me. Students are usually required to enrol for courses and tests. There are different procedures for both. 10.1 Courses Students may register for specific courses on Blackboard (http://blackboard.tudelft.nl). Most of the communication between lecturers and students takes the form of Blackboard announcements, along with exchange of information, assignments and reports. 10.2 Tests Enrolling for tests is obligatory and can be done on the TAS site (Tentamen Aanmeld Systeem: http://www.tas.tudelft.nl). Students should enrol two weeks at the latest before tests take place, otherwise tests will not be accounted for by the lecturer. If a student has registered but decides not to do the test, the student must cancel at least one week before the test is due to take place. When using TAS for the first time, students must choose a personal password. This can be done by using the campus card in a card reader. At the Faculty there are two card readers: one near the Pallas/Parthemus computer room (4, 1st) and one at Education Support Staff (8B, 2nd floor). 10.3 Pass rules To pass a course or assignment, a grade of 6 or above is needed. It is possible to pass the MSc with one grade of 5. Grades are rounded off to the nearest integer. Pass rules will change for students starting September 2009. 10.4 Examination On completing the programme, students should apply for the masters examination by means of a form which is available from the Education Support Staff. 10.5 Cum laude At the discretion of the examinations board, a candidate for the masters degree may receive the designation cum laude if he/she meets the following conditions: a. the mark awarded to the components specified in the masters examination implementation procedures shall average no less than 8, excluding the masters thesis, in a list that contains no marks below 6; b. the candidate concerned shall have completed the masters degree programme in no more than three half years; c. the mark awarded for the thesis project shall be no less than 9; d. the examiner of the graduation assignment shall have submitted a proposal for the award of cum laude. This is part of the Regulations and Guidelines for the Board of Examiners available on http://www.studenten.tudelft.nl under 3me.
11. Organisation
11.1 Faculty 3ME 3mE is an abbreviation of Mechanical, Maritime and Materials Engineering. The 3mE Faculty offers the study programmes Biomedical Engineering (BME), Materials Science and Engineering (MSE), Mechanical Engineering (ME), Marine Technology (MT), Systems and Control (SC) and Offshore Engineering (OE). The Faculty also participates in the interfaculty MSc programme Transport, Infrastructure and Logistics (TIL). 11.2 Interfaculty masters programme BioMedical Engineering is an interfaculty masters programme. Three faculties collaborate in this programme: the Faculty of Applied Sciences, the Faculty of Electrical Engineering, Mathematics and Computer Science, and the Faculty of Mechanical, Maritime and Materials Engineering. The BME programme is run from the Faculty of Mechanical, Maritime and Materials Engineering. By bundling the BME knowledge in these faculties a broad BME programme could be realised. Additionally, there is close and intensive collaboration with clinical partners at Leiden University Medical Center (LUMC), the Erasmus Medical Center Rotterdam (Erasmus MC), and the Academic Medical Center Amsterdam (AMC). Clinical partners participate in first-year MSc teaching (LUMC and Erasmus MC), and in the tutoring of MSc projects in the second year (LUMC, Erasmus MC, and AMC). 11.3 Education support staff The education support staff support the Mechanical Engineering programmes and provide information for students relating to the study of Mechanical Engineering. The education support staff comprises the following:
Dr Eric Logtenberg Dorothea Brouwer Fatma inar
e.h.p.logtenberg@tudelft.nl d.j.w.m.brouwer@tudelft.nl f.s.cinar@tudelft.nl

Teuni Eden
t.eden@tudelft.nl
Lourdes Gallastegui Ewoud van Luik
M.L.GallasteguiPujana@tudelft.nl e.p.vanluik@tudelft.nl
Susanne van der Meer Dr Dick Nijveldt
s.d.w.m.vandermeer@tudelft.nl d.nijveldt@tudelft.nl
Mascha Toppenberg
m.p.i.toppenberg@tudelft.nl
Prof. Peter Wieringa Evert Vixseboxse
p.a.wieringa@tudelft.nl E.Vixseboxse@tudelft.nl Education Support Staff Mekelweg 2, 2628 CD Delft Location 8C, ground floor Tel: +31 (0)15 27 85499 Fax: +31 (0)15 27 88340
Manager, O&S Department Tel: +31 (0)15 27 89520 Assistant Coordinator Education Tel: +31 (0)15 27 83302 Assistant International Coordinator Tel: +31 (0)15 27 86753 Academic Counsellor Tel: +31 (0)15 27 82176 Academic Counsellor Tel: +31 (0)15 27 86591 Coordinator Education Tel: +31 (0)15 27 85734 Secretary and Quality Assurance Tel: +31 (0)15 27 85499 Educational Advisor Tel: +31 (0)15 27 85921 International MSc coordinator Tel: +31 (0)15 27 86959 Director of Education Tel: +31 (0)15 27 85763 Academic Counsellor Tel: +31 (0)15 27 82996
11.4 Education committee The education committee advises the Dean and the Education Director on the contents and the structure of the study programme and examinations. The education committee consists of four lecturers and four students. The Education Director, the Education Advisor and a student advisor also take part in meetings. Chairman Prof. F C T van der Helm Tel: +31 (0)15 27 85616 E-mail: F.C.T.vanderHelm@3me.tudelft.nl Secretary D Heersma Mekelweg 2 Room 8C-1-18 2628 CD Delft Tel: +31 (0)15 27 86400 E-mail: D.Heersma@3me.tudelft.nl 11.5 Board of Examiners The Board of Examiners consists of all lecturers involved in the study programme and is responsible for setting the rules and regulations for examinations and the assessment of examination results. Requests for changes to or deviations from the study programme should be addressed to the Board of Examiners. Chairman Prof. F C T van der Helm Tel: +31 (0)15 27 85616 E-mail: F.C.T.vanderHelm@tudelft.nl Secretary E P van Luik Tel: +31 (0)15 27 85734 E-mail: e.p.vanluik@tudelft.nl 11.6 Student association The masters programme has an active student association, Antonie van Leeuwenhoek, which organises meetings, break-out sessions, and other social events on a regular basis. Information can be found on avl.tudelft.nl and on the AVL Blackboard society. 11.7 MSc coordinator The MSc coordinator is the person to approach for questions or problems related to the individual study programme and for monitoring progress. Every student can consult the MSc coordinator to draw up an individual study programme made up of the following: obligatory courses, current ideas on a topic for the thesis project, specialisation courses bridging the gap between the obligatory courses and the thesis project and the use of the free elective space. Students submit their plans for approval to the Board of Examiners. In order to finish the programme in two years, students should plan to take an average of 30 credits of courses per semester. At the end of the first year students will meet with the MSc coordinator to discuss their progress and their plans for the remainder of the programme. Students are also asked to fill in a questionnaire to evaluate the masters programme. The MSc coordinator R. Happee can be contacted via: Tel: +31 (0)15 27 83213; e-mail coordinator-BME@tudelft.nl.
11.8 Academic Counsellor The Faculty has two student advisors on hand to give assistance and advice to students regarding study-related questions or problems, or other issues which might influence a students ability to study. The student advisor functions as a sounding board and as a confidential consultant to students. Individual help and advice Student advisors have no teaching responsibilities and can therefore devote themselves entirely to individual students and addressing problems which may be an obstacle to their study progress. Student advisors also sit on many boards and have contact with lecturers, so they are kept up to date with the latest in the Mechanical Engineering programme. Student advisors are also in contact with other student advisors and personal advisors at TU Delft and outside the University. Personal circumstances During sessions with a student advisor, personal and intimate information will often come up. Students can be assured that this information will be kept confidential. This kind of information will only be used after consultation with the student in appeals to the TU or the Faculty. Alerting the Examination Committee, professors, and other members of staff A student advisor may decide, under certain conditions, to alert the Board of Examiners or a professor to a specific student. Where necessary the student advisor becomes an intermediary between TU Delft personal advisors: student, deans, psychologists and physicians. The extent to which the student advisor pays attention to a student is up to the student. The student advisor keeps an eye on the study progress of most students and calls them up if necessary, but it is strongly recommended that students contact the student advisor themselves when a question or problem comes up. Waiting often exacerbates the problem. The two student advisors at the Faculty are available for any questions you might have. They also have their own areas of specialisation. Foreign Student Financial Support (FSFS) Delft University of Technology provides financial assistance to foreign students in the event that their studies are delayed due to special circumstances such as physical illness, physical or sensory disorders, mental problems, or insufficient organisation of the educational programme by the Faculty.
12. Further Information

This study guide is the main information source for the study programme. The website www.bme.tudelft.nl always contains the most recent information. Detailed course information is available in the Digital Study Guide via www.studiegids.tudelft.nl or via http://blackboard.tudelft.nl - here it is not necessary to log in; go to the Digital Study Guide tab. Procedures and forms as well as Course and Examination Regulations and Regulations and Guidelines for the Board of Examiners are available at http://www.studenten.tudelft.nl under 3me.

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Biomedical Engineering MSc programme Study Guide 2009/2010 www.bme.tudelft.

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p1/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p2/41

Specialisations within the MSc in BME programme................................................................ 15

Teaching in Leiden (LUMC) and Rotterdam (Erasmus MC)..................................................... 30

All BME masters courses .................................................................................................... 32

Study and traineeship abroad ............................................................................................. 36

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p4/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p5/41

Prof. Frans C.T. van der Helm

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p6/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p7/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p8/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p9/41

3. Qualifications of MSc in BME graduates

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p10/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p11/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p12/41

MSc: second year (60 EC)

Masters thesis project (38 EC)

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p14/41

5. Specialisations within the MSc in BME programme

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p15/41

Medical Instruments & Medical Safety (MIMS)

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p16/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p17/41

Tissue Biomechanics and Implants (TBI)

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p18/41

Medical Imaging (MI)

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p19/41

Medical Physics (MP)

Biomedical Instrumentation (BI)

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p21/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p22/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p23/41

Additional Bachelors Courses for admission to Biomedical Instruments (BI)

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p24/41

(TH/HBO) 6.2.1 Introduction

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p25/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p26/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p27/41

Pre-masters programme for Biomedical Instruments (BI)

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p28/41

Admission for students still in their academic bachelors programme

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p29/41

7. Teaching in Leiden (LUMC) and Rotterdam (Erasmus MC)

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p30/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p31/41

8. All BME masters courses

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p32/41

Table IX: BME courses at TU Delft O = Obligatory; R = Recommended; E = Elective;

* The combined courses ET4364 & WM0811ET represent 4EC

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p33/41

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p34/41

Mathematics and Engineering courses

WB2301 WB2303-08 WB2404 WB1413-04 WB2414-09 WB1451-05 WB5414-08 WBP202 WI4014TU

0/0/2/2 0/0/2/2 0/4/0/0 0/0/2/2 2/2/0/0 0/0/2/2 2/2/0/0

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p35/41

9. Study and traineeship abroad

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p36/41

10. Enrolling for courses and tests, pass rules

BIOMEDICAL ENGINEERING STUDY GUIDE 2009/2010 August 2009 - p37/41

e.h.p.logtenberg@tudelft.nl d.j.w.m.brouwer@tudelft.nl f.s.cinar@tudelft.nl