Beruflich Dokumente
Kultur Dokumente
1. Using the attached sheets, complete two different karyotypes: One normal male or One normal female,
One from the different disorders of your choice out of the four
2. Working slowly and carefully, using scissors cut out the chromosome on one page labeled 1 and find
its EXACT match elsewhere on the page (it will not be numbered). Cut out this chromosome and tape
BOTH chromosomes side by side on a data page that has the heading filled out.
3. Continue this procedure until you have matched all chromosomes and taped each of them in the
corresponding place on the data page.
4. If you are caught short of time, use the coin envelope to store any chromosomes you may have clipped
out and not matched. DO NOT CUT OUT ALL CHROMOSOMES AND THEN ATTEMPT TO
MATCH THEM!!! Cut out only one at a time or you will lose chromosomes.
5. In the event that you have an extra chromosome, DO NOT THROW IT OUT! It is the chromosome
that causes your mutation/disorder and you must match it correctly.
6. Once your chromosomes are all cut out and included in the karyotypes, answer the questions and
complete the lab.
Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.
NAME _______________________________
PRE-LAB Questions: Answer the following questions before turning in your lab.
1. Explain how would you determine if your karyotype was male or female?
2. Complete the table table below before performing the Karyotyping
Karyotype #1
Karyotype #2
Individual is a ____________________
Individual is a ____________________
Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.
NAME _______________________________
Chromosomes Picture #1
Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.
NAME _______________________________
Chromosome Picture #2
Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.
NAME _______________________________
Chromosome Picture #3
Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.
NAME _______________________________
Chromosome Picture #4
Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.
NAME _______________________________
Chromosome Picture #5
Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.
NAME _______________________________
Chromosome Picture #6
Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.
NAME _______________________________
ANALYSIS QUESTIONS:
2.
3.
4.
5.
6.
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What characteristics did you use to match up similar chromosomes known as homologous chromosomes?
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Which pairs on the human karyotype are known as autosomes?
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Which pairs on the human karyotype are known as sex chromosomes?
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Down Syndrome is known as trisomy 21. What does this mean in terms of the numbers of chromosome
and the type of abnormality?
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Why do you think that monosomy or trisomy of the autosomes is more detrimental to survival than
monosomy or trisomy of the sex chromosomes?
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Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.
NAME _______________________________
Some chromosomal abnormalities that can be detected by karyotyping are listed below:
1. Extra chromosome 21 - Down Syndrome - Associated with mental retardation, characteristic facial
features and stature, heart defects, respiratory infection, leukemia, and Alzheimers disease; occurs in 1 in 700 births
in U.S.
2. XXY - Klinefelter Syndrome - Typically sterile males with abnormally small testes, some female
characteristics, normal intelligence; occurs in 1 in 2000 births.
3. XYY - Double Y Syndrome - Affected individuals tend to be taller as a group, normal intelligence
XXX Distinguished from normal XX females only through karyotyping; occurs in 1 in 1000 births
4. XO - missing sex chromosome - Turner Syndrome - Sterile females with immature sex organs, normal
intelligence; occurs in 1 in 5,000 births
5. Partial chromosome 5 - Cri du chat Syndrome - Associated with small head, characteristic cry and facial
features, death in infancy or early childhood
Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.
NAME _______________________________
Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.
NAME _______________________________
Mr. Comets Living Environment Laboratory Manual, 2005-2006, South Lewis High School, Turin, New York 13473. Permission is granted for not-forprofit educational use by certified teachers.