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LECTURE 7
TSH may increase when supplementing with iodine. Don’t worry, this is temporary.
LV and KI convert T4 to T3 with 5’ diiodinase (Selenium and Zn = cofactors, also for thyroid peroxidase)
TPO levels decrease with selenium (in Graves)
Even pituitary, adipose tissue converts T4 to T3.
Why is t3 not measured
Reverse T3 is increased in times of stress. Slows down to preserve energy and metabolic rate. Will feel tired after loved
one dies, military cadet training…
If rT3 too high for too long, helpful to give T3 to eliminate rT3.
T3 is the main test that Dr. Friedman orders. But will still treat if body temperature is low.
Hashimotos and Graves: antibodies to thyroid peroxidase (TPO). One way of decreasing antibodies = Se (500-
700mcg/day) Maybe 1500mcg /day for
IL-6 increased in times of infection, also inhibits T4-T3. Chronic infection in Epstein-Barr, CFS.
Reset temp: iodine, blue flag, guggul, kelp, T2… Increases temperature again.
Exercise also a great way to increase temperature.
T3 and osteoporosis? One study found that total suppression of TSH caused more hip fractures in post-menopausal
women. Supplement with 10,000 IU Vitamin D, other bone minerals
T3 contraindications:
Severe adrenal insufficiency: no cortisol – need this! Can increase with licorice
Low metabolism (CFS), given heparin to thin blood. Blood so thick and sluggish, body can’t function well.
Taking BCP? Lower levels of free hormones of T3/T4. Estrogen dominance can indirectly cause thyroid low function.
Androgens will decrease levels of Thyroid binding hormone, more free hormone.
WT3 therapy: just give until patient’s temperature gets back to normal.
Study: N=11: when temperature was 98.6 (3 measurements per day, morning/afternoon/evening, take average over 3
days)
The treatment used here was T3
ADRENAL LECTURE
Adrenal glands = nerve tissue
Chronically nervous/stressed? Repercussions on adrenal function.
Hyperadrenocorticism
Immune suppression occurs in chronic stress
Can have bone loss
Dysglycemia with chronic stress
Body hair: low testosterone, but get androgen production, conversion to testosterone get hair and acne
Licorice solid extract: a ‘goop’ that you take with a spoon. Wise woman herbals makes one.
Best lab test for cortisol: doesn’t do much testing. More symptom based. Low body temperature and tired? Treat
adrenals and thyroid. Tonic herbs!!!
Salivary tests useful, not perfect. Also blood, urine.
Normal BP? Will give small amount of licorice extract (1/8 tsp)
Tinctures in notes are 1:4