Name of Drug Generic Name: Cefuroxime

Mechanism Dosage of Action It binds to 750 mg bacterial IV q8 membranes. It inhibits synthesis of bacterial cell wall.

Indication It is used to treat otitis media, respiratory tract, genitourniar y tract, gynecologic, skin, and bone infections. It is also used in the treatment of speticemia, bacterial meningitis, gonorrhea, and other gonococcal infections. It can also be used for ampicillinresistant influenza, perioperativ e prophylaxis, impetigo,

Contraindication Contraindicated in patients hypersensitive to drug or other cephalosporin. Use cautiously in patients hypersensitive to penicillin because of possibility of cross-sensitivity with other beta lactam antibiotics

Adverse Reaction/Side Effects Adverse Reactions: -Antibiotic-associated colitis -Superinfection -Nephrotoxicity -Severe hypersensitivity reactions Side Effects: -Discomfort with IM administration -Oral candidiasis (mouth and/or tongue sores) -Mild diarrhea -Mild abdominal cramping -Vaginal candidiasis -Nausea and Vomiting -Serum sickness reaction (joint pain, fever) -Allergic reactions -Thrombophlebitis

Nursing Consideration Question for history of allergies, particularly cephalosporins and penicillins. Give without regards to meals. If GI upset occurs give with food or milk. Avoid crushing tablets due to bitter taste. Suspension must be given with food. Intramuscular injections must be administered deep IM to minimize discomfort. Assess mouth for white patches on mucous membranes and tongue.

acute bacterial maxillary sinusitis, and early Lyme disease.

Monitor bowel activity and stool consistency carefully. Mild GI effects may be tolerable but increasing severity may indicate onset of antibioticassociated colitis. Monitor input and output and renal function reports for nephrotoxicity. Be alert for superinfection: severe genital or anal pruritus, abdominal pain, and severe mouth soreness, moderate to severe diarrhea. Discomfort may occur with IM injection. Doses should be

evenly spaced. Continue antibiotic therapy for full length of treatment. May cause GI upset (may take with food or milk).

Name of Drug Generic Name: Duavent

Mechanism of Action The combination of ipratropium and albuterol is used to prevent wheezing, difficulty of breathing, chest tightness, and coughing.

Dosage Nebule q6

Indication Management of reversible bronchospasms associated with obstructive airway disease, bronchial asthma.

Contraindication Hypertrophic obstructive cardiomyopathy or tachyarrhythmia. Hypersensitivity to atropine and its derivatives.

Adverse Reaction/Side Effects Headache, pain, influenza, chest pain, nausea. Bronchitis, dyspnea, coughing, pneumonia, bronchospasm, pharyngitis, sinusitis, rhinitis. Edema, fatigue, Hypertension, dizziness,

Nursing Consideration -Instruct the patient on how to use the nebulizer. -Instruct the patient in the frequency of the nebulization. - Instruct the patient what to do during the asthma attack. -Monitor

nervousness, paresthesia, tremor, dysphonia, insomnia, diarrhea, dry mouth, dyspepsia, vomiting, arrhythmia, palpitation, tachycardia, arthralgia, angina, increased sputum, taste perversion and UTI/dysuria. Allergic-type reactions.

therapeutic effectiveness which is indicated by significant subjective improvement in pulmonary function within60-90 min after drug administration. -Monitor for: S & Sx of fine tremor in fingers, which may interfere with precision handwork; CNS stimulation, particularly in children 2-6, (hyperactivity, excitement, nervousness, insomnia), tachycardia, GI symptoms. Report promptly to physician.