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Mendelian Genetics Practice Problems Prof. Corl Genetics Practice Problem #1.

) Cross involving one trait: In pea plants, the allele for purple colored flowers (P) is dominant while the allele for white colored flowers (p) is recessive. You decide to set up a cross (a mating) between a male parent that has white flowers to a female parent that is heterozygous for flower color. What are the genotypes of the parents? ______________________ Construct a Punnett Square in the space below to illustrate: 1.) The different gametes produced by each parent. 2.) The different possible genotypes of the offspring generation (F1 generation) that would result from the cross described above.

Based on your Punnett square: What are the genotypes of the offspring and what percentage of the offspring will have each of the genotypes (that is, what are the expected F1 genotypic ratios)?

What are the phenotypes of the offspring and what percentage of the offspring will have each of the phenotypes? (that is, what are the expected F1 phenotypic ratios)?

Genetics Practice Problem #2.) Cross involving two unlinked traits: In pea plants, the allele for round seeds (R) is dominant while the allele for wrinkled seeds (r) is recessive. In addition, the allele for yellow pea pods (Y) is dominant while the allele for green pea pods (y) is recessive. You decide to set up a cross (a mating) between the following two parents: Parent #1: Heterozygous for seed shape. Has green pea pods. Parent #2: Heterozygous for both seed shape and pea pod color. What are the genotypes of the parents? Parent #1 Genotype: _____________ Parent #2 Genotype: _____________ Construct a (large) Punnett Square in the space below to illustrate: 1.) The different gametes produced by each parent. 2.) The different possible genotypes of the offspring generation (F1 generation) that would result from the cross described above.

Based on your Punnett square: What are the genotypes of the offspring and what percentage of the offspring will have each of the genotypes (that is, what are the expected F1 genotypic ratios)? What are the phenotypes of the offspring and what percentage of the offspring will have each of the phenotypes? (that is, what are the expected F1 phenotypic ratios)?

Genetics Practice Problem #3.) Cross involving a sex-linked trait In fruit flies (Drosophila melanogaster), the most common eye color is red (w+). A mutation (or allele) of the gene for eye color produces white eyes (w). The red eye allele is dominant to the white eye allele. The gene is located on the X chromosome. You decide to set up a cross (a mating) between the following two parents: Male parent: Has red eyes. Female parent: Heterozygous for eye color. What are the genotypes of the parents? Male parent genotype: _____________ Female parent genotype: _____________ Construct a Punnett Square in the space below to illustrate: 1.) The different gametes produced by each parent. 2.) The different possible genotypes of the offspring generation (F1 generation) that would result from the cross described above.

Based on your Punnett square: What are the genotypes of the offspring and what percentage of the offspring will have each of the genotypes (that is, what are the expected F1 genotypic ratios)?

What are the phenotypes of the offspring and what percentage of the offspring will have each of the phenotypes? (that is, what are the expected F1 phenotypic ratios)? Be sure to indicate the sex (male or female) of each of your phenotypic classes.

Genetics Practice Problem #4) Cross involving incomplete dominance: In snapdragons, the alleles for flower color show incomplete (partial) dominance. Plants with two copies of the R allele have red flowers; plants with two copies of the r allele have white flowers; while plants with one of each allele have pink flowers. You decide to set up a cross (a mating) between two pink snapdragons. What are the genotypes of the parents? ______________________ Construct a Punnett Square in the space below to illustrate: 1.) The different gametes produced by each parent. 2.) The different possible genotypes of the offspring generation (F1 generation) that would result from the cross described above.

Based on your Punnett square: What are the genotypes of the offspring and what percentage of the offspring will have each of the genotypes (that is, what are the expected F1 genotypic ratios)?

What are the phenotypes of the offspring and what percentage of the offspring will have each of the phenotypes? (that is, what are the expected F1 phenotypic ratios)?

Genetics Practice Problem #5): Codominance In humans, ABO blood types refer to glyocproteins in the membranes of red blood cells. There are three alleles for this autosomal gene: IA, IB, and i. The IA allele codes for the A glycoprotein, the IB allele codes for the B glycoprotein, and the i allele doesn't code for any membrane glycoprotein. IA and IB are codominant, and i is recessive to both IA and IB. People with A type blood have the genotypes IAIA or IAi, people with type B blood are IBIB or IBi, people with type AB blood are IAIB, and people with O type blood are ii. If a woman with type AB blood marries a man with type O blood: Construct a Punnett Square in the space below to illustrate: 1.) The different gametes produced by each parent. 2.) The different possible genotypes of the offspring generation (F1 generation) that would result from the cross described above.

Based on your Punnett square: What are the genotypes of the offspring and what percentage of the offspring will have each of the genotypes (that is, what are the expected F1 genotypic ratios)?

What are the phenotypes of the offspring and what percentage of the offspring will have each of the phenotypes? (that is, what are the expected F1 phenotypic ratios)?

Challenging Genetics Problem Give it a try! 6.) In Klingons, one gene determines hair texture; another gene determines whether the individual will have a sagittal crest (a protrusion on the forehead). The two genes are not linked. In fact, the gene for hair texture is on the X chromosome (is sex-linked) while the gene for forehead shape is autosomal (is not sex-linked). (You may safely assume that, like in humans, Klingon females have two X chromosomes while Klingon males have one X chromosome and one Y chromosome.) C = curly Klingon hair (dominant) c = silky earthling-like hair (recessive) L = large sagittal crest (dominant) l = smooth, flat, earthling-like forehead (recessive) Bijou, a female Klingon, is heterozygous for both traits. She mates with a male who has curly Klingon hair and a smooth, flat, earthling-like forehead. What are the genotypes of the two parents? ___________ and ___________ Construct a Punnett Square in the space below to illustrate: 1.) The different gametes produced by each parent. 2.) The different possible genotypes of the offspring generation (F1 generation) that would result from the cross described above.

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