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In The Name of Allah Most Gracious Most Merciful

DEPARTMENT OF HEALTH AND MEDICAL SCIENCES


DEPARTMENT OF SCIENCES
CENTRE FOR FOUNDATION STUDIES
INTERNATIONAL ISLAMIC UNIVERSITY MALAYSIA

BIOLOGY 1
HMM/ SCM1414
Tutorial 4 (CELL DIVISION)

Semester 1, 2007/2008

Answer all questions on these question papers.

Name : ……………………………………………………

Matric. No : ……………………………………………………

Programme : ……………………………………………………

Group no : ……………………………………………………

For Examiner’s Use

Section Question Marks


A Objective
B
C

Total Marks

__________________________________________________
This question paper consists of 12 printed pages
SECTION A
Circle the correct answer

1 Diagram 1 shows a particular phase in an onion cell mitotic


division.

Diagram 1

Determine the phase shown in Diagram 1.

A Prophase B Metaphase
C Anaphase D Telophase

2 In which phase of the cell cycle, are the chromosomes


duplicated?

A S phase B G1 phase
C G2 phase D M phase

3 Cdk, MPF and cyclin are the cell products which involve in the
regulation of cell cycle. Which of the following condition initiates
mitosis to start?

A Gradual increase in cyclin concentration


B Gradual increase in MPF concentration
C Sudden decrease in MPF concentration
D Sudden decrease in Cdk concentration

4 In which phases are the checkpoints of the cell cycle control


system?

I G1 II G2 III M IV S
A I and II B I, II and III
C I, II and IV D I, II, III and IV

5 Which of the following statements are true regarding the


chromosome structure?

I Composed of nucleosomes
II Contains DNA and histone
III Consists of 150 million nucleotides
IV Consists of two sister chromatids joint by centromere

A I and II B I, II and IV
C I, II and III D II, III and IV

6 Which is the longest phase of the cell cycle?

A Interphase B Mitosis
C Cytokinesis D G2 phase

7 Cytokinesis in plant cells occurs by the formation of

A cell wall B cell plate


C aster D spindle apparatus

8 If a cell of one organism has eight chromosomes, how many


chromosomes does the organism have in its gamete?

A Two B Four
C Eight D Sixteen

9 In a plant cell, a centrosome functions in the formation of

A asters B centrioles
C kinetochores D spindle apparatus
10 Which of the following describe/s sister chromatids?

I Each has its own kinetochore


II They are formed during prophase
III Moves to the opposite poles during telophase
IV Each has half the amount of the original chromosome’s
genetic material
A I only B III only
C III and IV D II, III and IV
SECTION B

Figure 1 shows the arrangement of two pairs of homologous


chromosomes in a particular stage during mitosis in a cell.

Figure 1

a) Name the mitotic stage shown in this figure. [1]

…………………………………………………………………………………………………….

b) i. Identify P. [1]

………………………………………………………………………………………….

ii. What is the role of P? [1]

…………………………………………………………………………………………..

iii. Name the protein subunits which make up P. [1]

…………………………………………………………………………………………..
c) In the box below, draw the chromosomes in a gamete produced
by normal meiotic division of the chromosomes shown in
Figure 1. ( Assume that crossing over does not occur) [2]

d) In the box below, draw one of the pairs of homologous


chromosomes as they would appear after crossing over has
occurred during meiosis. [2]
SECTION C

1 Describe the life cycle of one chromosome as it proceeds through


the entire cell cycle. [15]

2 a) Describe the relative concentration of MPF, cyclins, and


Cdks throughout the cell cycle. [10]

b) Define MPF and discuss briefly its role in the cell cycle. [5]

3 Do comparison between the chromosomal behaviour in meiosis


and mitosis. [15]

4 Compare and contrast the detailed meiotic stages in plant and


animal cells. [15]

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