Name: ________________ HISTOLOGY - EXAMINATION 3 November 10, 2008 On the bottom, left side of the answer sheet, write

your Name (last name first, first name second), Histology 1 (under subject), and todays date. Write your student number in the area labeled Student I.D. Number(bottom right corner) using the first boxes (no dashes, please) and fill in the appropriate boxes below the numbers. Finally, in the section labeled Key ID (upper left hand corner) fill in whether you have the "A", "B", "C" or "D" examination. When finished, place the answer sheet inside the exam booklet and hand in both to a proctor. The following 50 questions are of the multiple choice variety. Select the choice which best answers each question and record it on the answer sheet. Please use a number 2 pencil only. When changing an answer, erase the original answer as thoroughly as possible and then record the new answer on the answer sheet. EXAMINATION A
1. Which component of the membranous labyrinth contains otoliths? A. Utricle B. Endolymphatic sac C. Stria vascularis D. Inner tunnel E. Ampullae Osteoblasts have receptors for all of the following except: A. estrogen B. calcitonin C. 1,25-dihydroxyvitamin D3 D. cytokines E. parathyroid hormone In a 50-year-old female, where in the body would you expect to find a synostosis? A. Pubic symphysis B. The articulation of the distal tibia and fibula C. The articulation of the first rib and sternum D. The union of the metaphysis and diaphysis in a long bone E. Temporomandibular joint Carbohydrates released by which structure provide energy for sperm motility? A. Rete testis B. Seminal vesicle C. Ejaculatory duct D. Bulbourethral glands E. Prostate gland Which component of the endocrine system is stimulated by aldosterone? A. Pineal gland B. Adrenal medulla C. Zona glomerulosa D. Neurohypophysis E. Pars intermedia

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In the bronchi, the transformation of respiratory mucosa to a non-premalignant stratified squamous epithelium is known as: A. Anaplasia B. Neoplasia C. Dysplasia D. Hyperplasia E. Metaplasia How much time normally elapses between osteoid deposition and mineralization? A. 6-8 hours B. 5-7 days C. 12-15 days D. 20-25 days E. 30 days Which of the following structures is not involved in sound transmission? A. Malleus B. Tympanic membrane C. Saccule D. Vestibulocochlear nerve E. Scala tympani Which of the following structures is found in the outer layer of the eye? A. Choroid B. Cornea C. Ciliary body D. Iris E. Retina What is the function of human chorionic gonadotropin? A. Stimulation of spermatogenesis. B. It triggers ovulation. C. Maintenance of the corpus luteum during pregnancy. D. Stimulation of ductal growth in the breast. E. Stimulation of ovarian follicle development Thyroxine is produced in the: A. thyrotrophs B. pineal gland C. neurohypophysis D. zona reticularis E. colloid Primary spermatocytes are derived from which cell? A. Type A spermatogonia B. Type B spermatogonia C. Round spermatids D. Spermatozoa E. Elongated spermatids

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Which component of the nasal cavity functions in warming inspired air? A. Lymphoid tissue B. Large veins C. Seromucous glands D. Vibrissae E. Olfactory organ The articular disk rests between the mandibular condyle and the: A. maxilla. B. mandible. C. temporal bone. D. sphenoid bone. E. zygoma. The collection of granulation tissue, new bone, and cartilage found at an osseous fracture site is known as the: A. growth plate. B. callus. C. cortex. D. symphysis. E. procallus. In the male genital ducts, the structure that follows the efferent duct is/are the: A. epididymis B. rete testis C. ejaculatory duct D. seminiferous tubules E. vas deferens A patient visits his physician for his annual physical exam. Noticing a firm swelling on his distal femur, the doctor orders radiographs and a blood chemistry analysis. If the patient has a boneforming tumor, which of the following compounds will have elevated serum levels? A. Hydroxyproline B. Tartrate-resistant acid phosphatase C. Parathyroid hormone D. Alkaline phosphatase E. Collagen type I The wall of the gall bladder lacks a: A. serosa. B. muscularis externa. C. muscularis mucosae. D. lamina propria. E. submucosa. The aqueous humor is secreted into the eye by the: A. choroid. B. iris. C. canal of Schlemm. D. retinal pigment epithelium. E. ciliary processes.

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What cells are found in isogenous groups? A. Fibroblasts B. Chondrocytes C. Osteoblasts D. Osteoclasts E. Osteocytes What tissue joins the arms of the tracheal cartilages across the back of the trachea? A. Respiratory epithelium B. Mesothelium C. Dense irregular connective tissue D. Elastic connective tissue E. Smooth muscle Which compound directly contributes to the development of the breast alveoli? A. Oxytocin B. Estrogen C. Luteinizing hormone D. Prolactin E. Progesterone Secretion by which cell population within the islet of Langerhans results in increased cellular glucose uptake? A. A cells B. B cells C. C cells D. F cells E. G cells What accounts for approximately 90% of the organic component of bone? A. Osteocalcin B. Type I collagen C. Bone sialoprotein D. Osteopontin E. Hydroxyapatite Cell processes of the _______ converge to become the optic nerve. A. rods and cones B. amacrine cells C. ganglion cells D. monosynaptic bipolar neurons E. horizontal cells Most of the bone in the jaws arises through membranous bone formation. A. True B. False Not counting water, ______ accounts for approximately half the weight of hyaline cartilage. A. chondronectin B. glycosaminoglycans C. collagen D. calcium E. proteoglycans

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The most peripheral aspect of the diaphysis of a long bone will exhibit: A. endosteum. B. bone marrow. C. non-lamellar bone. D. articular cartilage. E. circumferential lamellae. Pulmonary surfactant is released by the: A. Clara cells. B. Type I pneumocytes. C. Type II pneumocytes. D. Goblet cells E. Dense core granule cells. Which of the following glands functions through a vascular portal system? A. Pineal B. Pituitary C. Thyroid D. Parathyroid E. Adrenal A ham-fisted dentist attempts to extract a maxillary second molar and mistakenly breaks off a root tip. Which anatomic structure is the root tip most likely to enter? A. Maxillary sinus B. Ethmoid sinus C. Nasopharynx D. Frontal sinus E. Nasal cavity All of the following are involved in membrane bone formation except: A. osteoid. B. mesenchyme. C. a chondroid template. D. collagen. E. osteoblasts. Which of the following cells/structures are found in the external ear? A. Organ of Corti B. Ceruminous glands C. Incus D. Pillar cells E. Macula What is the secretory product of Leydig cells? A. Inhibin B. Androstenedione C. Testosterone D. Renin E. Estrogen Blood vessels from the periosteum enter into long bones by way of: A. Haversian canals. B. the epiphyseal growth plate. C. Volkmanns canals. D. a procallus. E. Howships lacunae.

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The production of secretin by the small intestine will lead to the: A. breakdown of dietary fat. B. contraction of the gall bladder. C. hydrolysis of peptide bonds. D. neutralization of acidic alimentary contents. E. reduction of gastrointestinal peristalsis. Osteocytic osteolysis results in a net decrease in bone mass. A. True B. False Which of the following hormones stimulates smooth muscle contraction? A. Growth hormone B. Antidiuretic hormone C. Follicle stimulating hormone D. Melanocyte stimulating hormone E. Oxytocin Where in the human body would one expect to find elastic cartilage? A. Epiphyseal growth plate B. Articular surfaces of bone C. Intervertebral discs D. Pubic symphysis E. Epiglottis A disease that gradually destroys the parenchymal cells of the ______ will lead to blood clotting deficiencies. A. liver B. exocrine pancreas C. islets of Langerhans D. gall bladder E. None of the above At which surface does the lateral pterygoid muscle insert into the articular disk? A. Inferior B. Anterior C. Posterior D. Medial E. Lateral During the process of endochondral ossification of a long bone, bone formation first occurs at which site(s)? A. The metaphyses B. The surface of the epiphyses C. The central (internal) portion of the epiphyses D. The central (internal) portion of the diaphysis E. The surface of the mid-region of the diaphysis

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A pathologist is evaluating a thyroid biopsy from a patient with a known tumor of pituitary basophils, which has resulted in abnormally high TSH levels. What histologic changes would be seen in the thyroid tissue? A. Increased numbers of thyrotrophs B. Squamous follicular cells and little colloid C. Cuboidal follicular cells and abundant colloid D. Columnar follicular cells and little colloid E. Columnar follicular cells and abundant colloid The lubricant within synovial fluid is secreted by: A. type I synovocytes. B. type II synovocytes. C. endothelial cells. D. goblet cells. E. fibroblasts. All of the following anatomic structures directly contact the pharynx except the: A. nasal cavity. B. larynx. C. maxillary sinus. D. oral cavity. E. esophagus. The secretory portion of the breast is similar in structure and function to a ______ gland. A. minor salivary B. sweat C. sebaceous D. gastric E. Brunners The secretion of _______ will result in an elevated heart rate. A. growth hormone B. epinephrine C. oxytocin D. androstenedione E. calcitonin What is a function of the retinal pigment epithelium? A. Form synapses between rods and cones B. Respond to light in low light conditions C. Respond to light in the color spectrum D. Transport vitamin A to the rods and cones E. Produce aqueous humor As you proceed down the respiratory tree towards the pleura, at what component will gas exchange first occur? A. Bronchi B. Respiratory bronchiole C. Alveolar duct D. Terminal bronchiole E. Alveolus Which hormone stimulates the development of spermatozoa? A. Follicle stimulating hormone B. Luteinizing hormone C. Prolactin D. Somatotropin E. Serotonin

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Practical Examination For each question choose the single best answer. Read each question carefully and pay close attention to what the pointer is indicating, if anything. 1. Name the specified tissue. A. Fibrocartilage B. Non-lamellar bone C. Articular cartilage D. Hyaline cartilage E. Elastic cartilage 2. Name the structure at the indicator. A. Pars intermedia B. Infundibulum C. Pars distalis D. Pars nervosa E. Pars tuberalis 3. The indicator is in the lumen of what structure? A. Efferent duct B. Rete testis C. Vas deferens D. Seminal vesicle E. Seminiferous tubule 4. Name the structure at the arrow. A. Kinocilium B. Tectorial membrane C. Stria vascularis D. Vestibular (Reissners) membrane E. Basilar membrane 5. Name the indicated structure. A. Corpus leuteum B. Antral follicle C. Tunica albuginea D. Primordial follicle E. Corpus albicans 6. The indicator is in the lumen of a/the: A. branch of the hepatic artery B. branch of the portal vein C. distributing vein D. central vein E. sinusoid 7. Name the indicated cell. A. Fibroblast B. Osteocyte C. Osteoclast D. Osteoblast E. Chondrocyte 8. Name the organ. A. Pineal gland B. Anterior pituitary gland C. Adrenal medulla D. Adrenal cortex E. Parathyroid gland 9. Name the structure. A. Corpus leuteum B. Zona pellucida C. Corona radiata D. Stratum compactum E. Pre-antral follicle 10 Name the structure. A. Ciliary process B. Conjunctiva C. Pigment epithelium D. Dilator pupillae muscle E. Iris 11. Name the indicated cell. A. Chondrocyte B. Osteoblast C. Megakaryocyte D. Osteoclast E. Osteocyte 12. The indicator is in the lumen of a(n): A. Tertiary bronchus B. Alveolar duct C. Respiratory bronchiole D. Alveolus E. Terminal bronchiole 13. Name the indicated cell. A. Chondrocyte B. Osteoblast C. Megakaryocyte D. Osteoclast E. Osteocyte 14. What compound is secreted from this structure? A. Glucagon B. Parathyroid hormone C. Follicle stimulating hormone D. Calcitonin E. Aldosterone

15. Name the structure/organ. A. Parathyroid gland B. Thyroid gland C. Pars intermedia D. Exocrine pancreas E. Pineal gland 16. Name the structure at the indicator. A. Zona pellucida B. Granulosa layer C. Granulosa leuteum D. Theca externa E. Theca interna 17. Name the tissue. A. Compact bone B. Cancellous bone C. Elastic cartilage D. Hyaline cartilage E. Osteoid 18. Name the cell at the indicator. A. Bipolar cell B. Ganglion cell C. Amacrine cell D. Horizontal cell E. Mller cell 19. Name the cell at the indicator. A. Spermatid B. Sertoli cell C. Leydig cell D. Spermatagonion E. Spermatocyte 20. Name the tissue/structure indicated by the arrow. A. Cortical bone B. Elastic cartilage C. Articular cartilage D. Epiphyseal growth plate E. Periosteum