ACUTE LEUKEMIA CLINICAL TRIALS

DISCLAIMER:- The Following Clinical Trials are from our 2005 review and are
NOT in our current reviews. They are listed only as examples of what is written in our
clinical trials reviews.
rHuEPO and treatment outcomes: the clinical experience.

Hudis CA, Van Belle S, Chang J, Muenstedt K.

Breast Cancer Medicine Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue,
New York, NY 10021, USA. hudisc@mskcc.org

Increasingly, anemia is being recognized as a negative prognostic and predictive factor for
patients undergoing chemotherapy, radiation therapy, or a combination of these treatment
modalities. The results of clinical studies have shown correlations between anemia and shorter
survival times in patients with a wide variety of solid tumors and hematologic malignancies,
including lung, ovarian, breast, and head/neck cancers, non-Hodgkin's lymphoma, Hodgkin's
disease, Waldenstrom's macroglobulinemia, and chronic lymphocytic leukemia. Also, anemia has
been shown to predict treatment response in patients with ovarian, cervical, and urothelial
cancers, mantle cell lymphoma, and chronic lymphocytic leukemia, as well as refractory/relapsed
acute myelogenous leukemia. Based on the presumed causal relationship between anemia and
poor patient outcome, several studies have examined the influence of epoetin alfa (a recombinant
human erythropoietin) on outcomes in anemic patients undergoing cancer treatment. The results
of these studies have been encouraging, with indications of greater locoregional tumor control
and higher response rates in epoetin alfa-treated patients. Additionally, epoetin alfa therapy, by
correcting anemia, has been shown to improve a patient's energy level, ability to perform daily
activities, and overall quality of life (QOL). Such effects not only enhance a patient's general
well-being, but may also increase their tolerance of, and willingness to undergo, full courses of
their cancer therapy in a timely manner. These findings support the use of epoetin alfa to achieve
gains in QOL and cancer treatment outcomes in anemic cancer patients and suggest that
additional studies be conducted to further investigate the potential benefits of this agent in regard
to improved outcomes.

SB-715992 in Treating Patients With Acute Leukemia, Chronic Myelogenous Leukemia, or

Advanced Myelodysplastic Syndromes.
RATIONALE: Drugs used in chemotherapy, such as SB-715992, work in different ways to stop
cancer cells from dividing so they stop growing or die.
PURPOSE: Phase I trial to study the effectiveness of SB-715992 in treating patients who have
acute leukemia, chronic myelogenous leukemia, or advanced myelodysplastic syndromes.
California
City of Hope Comprehensive Cancer Center, Duarte, California, 91010-3000, United
States; Recruiting
Clinical Trials Office - New Patient Services 800-826-4673 becomingapatient@coh.org

Ohio
Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve
University, Cleveland, Ohio, 44106-5055, United States; Recruiting
Brenda W. Cooper, MD 216-844-3213 bxc12@po.cwru.edu

Sirolimus in Treating Young Patients With Relapsed or Refractory Acute Leukemia.

RATIONALE: Drugs used in chemotherapy such as sirolimus use different ways to stop cancer
cells from dividing so they stop growing or die.
PURPOSE: Phase I trial to study the effectiveness of sirolimus in treating young patients who
have relapsed or refractory acute leukemia or non-Hodgkin's lymphoma.
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104, United
States; Recruiting Susan Rheingold, MD 215-590-2801 rheingold@email.chop.edu

Flavopiridol, Cytarabine, and Mitoxantrone in Treating Patients With Acute Leukemia.

RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from
dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
PURPOSE: Phase II trial to study the effectiveness of combining flavopiridol and cytarabine
with mitoxantrone in treating patients who have acute leukemia.
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland,
21231, United States; Recruiting Judith E. Karp, MD 410-502-7726

3-AP Followed By Fludarabine In Treating Patients With Relapsed or Refractory Acute or

Chronic Leukemia.
RATIONALE: Drugs used in chemotherapy, such as fludarabine, work in different ways to stop
cancer cells from dividing so they stop growing or die. 3-AP may help fludarabine kill more
cancer cells by making them more sensitive to the drug.
PURPOSE: This phase I trial is studying the side effects and best dose of fludarabine when given
together with 3-AP in treating patients with relapsed or refractory acute leukemia, chronic
leukemia, or high-risk myelodysplastic syndrome.
Georgia
Blood and Marrow Transplant Group of Georgia, Atlanta, Georgia, 30342-4777, United
States; Recruiting
Lawrence E. Morris, MD 404-255-1930 lmorris@bmtga.com

Maryland
Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore,
Maryland, 21201, United States; Recruiting
Ivana Gojo, MD 410-328-2565

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland,

21231, United States; Recruiting
Judith E. Karp, MD 410-502-7726

Texas
MD Anderson Cancer Center at University of Texas, Houston, Texas, 77030-4095, United
States; Recruiting
Francis J. Giles, MD 713-792-7305 fgiles@mdanderson.org

Monoclonal Antibody Therapy in Treating Patients With Ovarian Epithelial Cancer, Melanoma,
Acute Myeloid Leukemia.
RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver
tumor-killing substances to them without harming normal cells.
PURPOSE: Phase I trial to study the effectiveness of monoclonal antibody therapy in treating
patients who have acute myeloid leukemia.
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts,
02115, United States; Recruiting F. Stephen Hodi, MD 617-632-5053

Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or

Refractory Acute Lymphoblastic Leukemia.
RATIONALE: Chemotherapy drugs, such as ifosfamide, carboplatin, and etoposide, work in
different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal
antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing
substances to them without harming normal cells. Combining ifosfamide, carboplatin, and
etoposide with rituximab may kill more cancer cells.
PURPOSE: This phase II trial is studying how well rituximab together with ifosfamide,
carboplatin, and etoposide works in treating young patients with recurrent or refractory acute
lymphoblastic leukemia.

Alabama
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham,
Alabama, 35233, United States; Recruiting
Robert P. Castleberry, MD 205-939-9285 rcastleberry@peds.uab.edu

University of South Alabama Cancer Research Institute, Mobile, Alabama, 36604, United
States; Recruiting
Felicia L. Wilson, MD 251-405-5115 fwilson@usouthal.edu

Arizona
Arizona Cancer Center at University of Arizona Health Sciences Center, Tucson, Arizona,
85724, United States; Recruiting
Rochelle Bagatell, MD 520-626-4851

Phoenix Children's Hospital, Phoenix, Arizona, 85016, United States; Recruiting

Jessica Boklan, MD 602-546-0920

Arkansas
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little
Rock, Arkansas, 72205, United States; Recruiting
David L. Becton, MD 501-320-5650

California
Chao Family Comprehensive Cancer Center at University of California Irvine Medical
Center, Orange, California, 92868, United States; Recruiting
Stanley Calderwood, MD 714-456-6615 scalderw@uci.edu

Children's Hospital and Health Center, San Diego, San Diego, California, 92123-4282,
United States; Recruiting
Richard Kadota, MD 858-966-5811

Children's Hospital and Research Center at Oakland, Oakland, California, 94609-1809,

United States; Recruiting
James H. Feusner, MD 510-428-3000 jfeusner@mail.cho.org

Children's Hospital Central California, Madera, California, 93638-8762, United

States; Recruiting
Vonda Lee Crouse, MD 559-353-5480 vcrouse@childrenscentralcal.org

Children's Hospital Los Angeles, Los Angeles, California, 90027-0700, United

States; Recruiting
Paul S. Gaynon, MD 323-669-2163 pgaynon@chla.usc.edu

Children's Hospital of Orange County, Orange, California, 92868, United States; Recruiting

Wei-Ping Violet Shen, MD 714-516-4348 vshen@choc.org

General Robert Huyser Cancer Center at David Grant Medical Center, Travis Air Force
Base, California, 94535, United States; Recruiting
Peter J. Chenaille, MD 707-423-7176

Jonathan Jaques Children's Cancer Center at Miller Children's Hospital, Long Beach,
California, 90801-1428, United States; Recruiting
William Mark Roberts, MD 562-933-8600 wmroberts@memorialcare.org

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, 90095-1781,

United States; Recruiting
Stephen A. Feig, MD 310-825-5268

Kaiser Permanente Medical Center - Sacramento, Sacramento, California, 95825, United

States; Recruiting
Vincent A. Kiley, MD 916-973-7331 vincent.kiley@kp.org

Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California, 95051-5386,
United States; Recruiting
Carolyn Lucille Russo, MD 408-236-5028 carolyn.l.russo@kp.org

Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego, San Diego,
California, 92120, United States; Recruiting
Wellington Loh, MD 619-516-6144

Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma
Linda, California, 92354, United States; Recruiting
Antranik Bedros, MD 909-558-8626 abedro@ahs.llumc.edu

Lucile Packard Children's Hospital at Stanford University Medical Center, Palo Alto,
California, 94304, United States; Recruiting
Neyssa M. Marina, MD 650-723-5535 neyssa.marina@stanford.edu

Rebecca and John Moores UCSD Cancer Center, La Jolla, California, 92093-0658, United
States; Recruiting
Richard Kadota, MD 858-657-7020

Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, Los

Angeles, California, 90048, United States; Recruiting
Moshe Arditi, MD 310-423-4471

Santa Barbara Cottage Hospital, Santa Barbara, California, 93102, United

States; Recruiting
Felicity Hodder, MD 805-682-7111 fhodder@cottagehealthsystem.org

Southern California Permanente Medical Group, Downey, California, 90242, United

States; Recruiting
Willye B. Powell, MD 562-803-2472

Sutter Cancer Center, Sacramento, California, 95816, United States; Recruiting

Yisheng Lee, MD, PhD, MBA 916-733-1757

UCSF Comprehensive Cancer Center, San Francisco, California, 94143, United

States; Recruiting
Katherine K. Matthay, MD 415-476-3831

University of California Davis Cancer Center, Sacramento, California, 95817, United

States; Recruiting
Theodore Zwerdling, MD 916-734-2781 theodore.zwerding@ucdmc.ucdavis.edu

Colorado
Children's Hospital Cancer Center, Denver, Colorado, 80218, United States; Recruiting
Roger Howard Giller, MD 303-861-6892 giller.roger@tchden.org

Presbyterian - St. Luke's Medical Center, Denver, Colorado, 80218, United

States; Recruiting
Stephen R. Palmer, MD 719-471-2462

Connecticut
Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health
Center, Farmington, Connecticut, 06360-7106, United States; Recruiting
Arnold J. Altman, MD 860-545-9630

Yale Comprehensive Cancer Center, New Haven, Connecticut, 06520-8064, United

States; Recruiting
Jack van Hoff, MD 203-785-4640 jack.vanhoff@yale.edu

Delaware
 Alfred I. duPont Hospital for Children, Wilmington, Delaware, 19899, United
States; Recruiting
Rita S. Meek, MD 302-651-5502 rmeek@nemours.org

District of Columbia
Children's National Medical Center, Washington, District of Columbia, 20010-2970, United
States; Recruiting
Nita Louise Seibel, MD 202-884-2144 nseibel@cnmc.org

Lombardi Cancer Center at Georgetown University Medical Center, Washington, District of

Columbia, 20007, United States; Recruiting
Aziza Shad, MD 202-444-2224 shada@georgetown.edu

Florida
All Children's Hospital, St. Petersburg, Florida, 33701, United States; Recruiting
Jerry L. Barbosa, MD 727-892-4231 barbosaj@allkids.org

Baptist-South Miami Regional Cancer Program, Miami, Florida, 33176-2197, United

States; Recruiting
Doured Daghistani, MD 786-596-1960

Broward General Medical Center, Fort Lauderdale, Florida, 33316, United

States; Recruiting
Rudolph R. Roskos, MD 954-355-4527 rroskos@nbhd.org

Children's Hospital of Southwest Florida, Fort Myers, Florida, 33908, United

States; Recruiting
Emad K. Salman, MD 239-432-3333 emad.salman@leememorial.org

Florida Hospital Cancer Institute, Orlando, Florida, 32804, United States; Recruiting
Jane Crofton, RN, BSN, OCN 407-303-2090

Jackson Memorial Hospital, Miami, Florida, 33136, United States; Recruiting

Stuart R. Toledano, MD 305-585-5635 stoledan@med.miami.edu

Joe DiMaggio Children's Hospital at Memorial, Hollywood, Florida, 33021, United

States; Recruiting
Iftikhar Hanif, MD 954-986-2234 ifhanif@aol.com

Miami Children's Hospital, Miami, Florida, 33155, United States; Recruiting

Enrique A. Escalon, MD 305-666-6511

Nemours Children's Clinic, Jacksonville, Florida, 32207, United States; Recruiting

Eric Sandler, MD 904-390-3793 esandler@nemours.org

Nemours Children's Clinic-Orlando, Orlando, Florida, 32806, United States; Recruiting

Vincent F. Giusti, MD 407-650-7230
 Sacred Heart Children's Hospital, Pensacola, Florida, 32504, United States; Recruiting
John F. Kelleher, MD 850-505-4798 jfkelleh@neumous.org

Shands Cancer Center at the University of Florida Health Science Center, Gainesville,
Florida, 32610-0296, United States; Recruiting
Stephen P. Hunger, MD 352-392-5633 hungersp@peds.ufl.edu

St. Joseph's Children's Hospital, Tampa, Florida, 33677-4227, United States; Recruiting
Cameron K. Tebbi, MD 813-870-4252 cameron.tebbi@baycare.org

St. Mary's Hospital, West Palm Beach, Florida, 33407, United States; Recruiting
Narayana Gowda, MD 561-840-6125 doctorgowda@hotmail.com

Georgia
AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta -
Scottish Rite Campus, Atlanta, Georgia, 30342, United States; Recruiting
Howard M. Katzenstein, MD 404-785-0853 howard.katzenstein@choa.org

Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical
Center, Savannah, Georgia, 31405, United States; Recruiting
Tribhawan S. Vats, MD 912-350-8194 vatsri@memorialhealth.com

MBCCOP-Medical College of Georgia Cancer Center, Augusta, Georgia, 30912-4000,

United States; Recruiting
Roger A. Vega, MD 706-721-3626

Medical Center of Central Georgia, Macon, Georgia, 31201, United States; Recruiting
Hassan Dannawi, MD 478-633-1104 dannawi.hassan@mccg.org

Hawaii
Cancer Research Center of Hawaii, Honolulu, Hawaii, 96813, United States; Recruiting
Robert Warren Wilkinson, MD 808-586-2979

MBCCOP - Hawaii, Honolulu, Hawaii, 96813, United States; Recruiting

Brian F. Issell, MD 808-586-3015 brian@crch.hawaii.edu

Tripler Army Medical Center, Honolulu, Hawaii, 96859-5000, United States; Recruiting
Braden Alan Shoupe, MD 808-433-6057

Idaho
Mountain States Tumor Institute - Boise, Boise, Idaho, 83712, United States; Recruiting
J. Martin Johnston, MD 208-381-2782 johnstom@slrmc.org

Illinois
Advocate Hope Children's Hospital, Oak Lawn, Illinois, 60453, United States; Recruiting
Sharad N. Salvi, MD 708-346-4094 sharad.salvi@advocatehealth.com

Children's Memorial Hospital - Chicago, Chicago, Illinois, 60614, United

States; Recruiting
Susan Lerner Cohn, MD 773-880-4562

Lutheran General Cancer Care Center, Park Ridge, Illinois, 60068-1174, United
States; Recruiting
Jong-Hyo Kwon, MD 847-723-5962 jong-hyo.kwon_md@advocatehealth.com

Rush University Medical Center, Chicago, Illinois, 60612, United States; Recruiting
Allen D. Korenblit, MD 312-942-5983 akorenbl@rush.edu

Saint Jude Midwest Affiliate, Peoria, Illinois, 61637, United States; Recruiting
John A. McCallister, MD 309-624-4945 john.mccallister@stjude.org

Southern Illinois University School of Medicine, Springfield, Illinois, 62794-9658, United

States; Recruiting
Gregory Brandt, MD 217-545-5817 gbrandt@siumed.edu

University of Chicago Cancer Research Center, Chicago, Illinois, 60601, United

States; Recruiting
James B. Nachman, MD 773-702-6808

University of Illinois Medical Center, Chicago, Illinois, 60612, United States; Recruiting
Mary Lou Schmidt, MD 312-996-6143 mls3@uic.edu

Indiana
Riley Children Cancer Center at Riley Hospital for Children, Indianapolis, Indiana, 46202-
5225, United States; Recruiting
Robert Fallon, MD, PhD 317-274-8784 rfallon@iupui.edu

St. Vincent Hospitals and Health Care Centers, Indianapolis, Indiana, 46260, United
States; Recruiting
Randy Alan Hock, MD, PhD, MMM 317-338-4673

Iowa
Blank Children's Hospital, Des Moines, Iowa, 50308, United States; Recruiting
Torrey Leighton Mitchell, MD 515-241-8912 mitchetl@ihs.org

Holden Comprehensive Cancer Center at University of Iowa, Iowa City, Iowa, 52242-1009,
United States; Recruiting
Raymond Tannous, MD 319-356-1905

John Stoddard Cancer Center at Iowa Methodist Medical Center, Des Moines, Iowa, 50309,
United States; Recruiting
Stephen C. Elliott, DO, PhD, FAAP 515-241-6000 elliotsc@ihs.org

Kansas
Wesley Medical Center, Wichita, Kansas, 67214, United States; Recruiting
David Rosen, MD 316-962-2025
Kentucky
Kosair Children's Hospital, Louisville, Kentucky, 40202-3830, United States; Recruiting
Salvatore J. Bertolone, MD 502-852-8450

Markey Cancer Center at University of Kentucky Chandler Medical Center, Lexington,

Kentucky, 40536-0284, United States; Recruiting
Martha F. Greenwood, MD 859-323-6771 mfgree0@pop.uky.edu

Louisiana
Children's Hospital of New Orleans, New Orleans, Louisiana, 70118, United
States; Recruiting
Lolie Chua Yu, MD 504-896-9740

MBCCOP - LSU Health Sciences Center, New Orleans, Louisiana, 70112, United
States; Recruiting
Jill Gilbert, MD 504-568-5613 jgilbe@lsuhsc.edu

Ochsner Cancer Institute at Ochsner Clinic Foundation, New Orleans, Louisiana, 70121,
United States; Recruiting
Marquis Zimri Hodes, MD, PhD 504-842-5230

Tulane Cancer Center at Tulane University Hospital and Clinic, New Orleans, Louisiana,
70112, United States; Recruiting
Marshall A. Schorin, MD 504-988-5412 mschori@tulane.edu

Maine
CancerCare of Maine at Eastern Maine Medial Center, Bangor, Maine, 04401, United
States; Recruiting
Judith B. Allen, MD 207-973-7520

Maine Children's Cancer Program, Scarborough, Maine, 04074-9308, United

States; Recruiting
Craig A. Hurwitz, MD 207-885-7565 hurwic@mmc.org

Maryland
Alvin and Lois Lapidus Cancer Institute at Sinai Hospital, Baltimore, Maryland, 21225,
United States; Recruiting
Joseph Michael Wiley, MD 410-601-5864 jwiley@lifebridehealth.org

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore,

Maryland, 21201-1595, United States; Recruiting
Neil Jeffrey Grossman, MD 410-328-2808 ngrossma@peds.umaryland.edu

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland,

21231-2410, United States; Recruiting
Cindy Schwartz, MD 410-955-7385 schwac@ijhmi.edu
 Walter Reed Army Medical Center, Silver Spring, Maryland, 20910, United
States; Recruiting
Kip R. Hartman, MD 301-319-9116

Massachusetts
Baystate Regional Cancer Program at D'Amour Center for Cancer Care, Springfield,
Massachusetts, 01107, United States; Recruiting
David A. Steele, MD 413-794-9338 david.steele@bhs.org

Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston,

Massachusetts, 02115, United States; Recruiting
Holcombe Edwin Grier, MD 617-632-3971 holcombe-grier@dfci.harvard.edu

Floating Hospital for Children, Boston, Massachusetts, 02111, United States; Recruiting
Cynthia S. Kretschmar, MD 617-636-5535 ckretschmar@tufts-nemc.org

UMASS Memorial Cancer Center - University Campus, Worcester, Massachusetts, 01655,

United States; Recruiting
Ghazala Naheed Usmani, MD 508-856-4225 usmanin@ummhc.org

Michigan
Breslin Cancer Center at Ingham Regional Medical Center, Lansing, Michigan, 48910,
United States; Recruiting
Renuka Gera, MD 517-334-2337

Bronson Methodist Hospital, Kalamazoo, Michigan, 49007-5364, United States; Recruiting

Leonard August Mattano, MD, PhD 616-341-6350

CCOP - Beaumont, Royal Oak, Michigan, 48073-6769, United States; Recruiting

Jeanne Archer, PhD, APN 248-551-8299 carcher@beaumon.edu

Children's Hospital of Michigan, Detroit, Michigan, 48201, United States; Recruiting

Yaddanapudi Ravindranath, MBBS 313-745-5649 ravi@med.wayne.edu

DeVos Children's Hospital, Grand Rapids, Michigan, 49503, United States; Recruiting
David Robert Freyer, DO 616-391-2086

Hurley Medical Center, Flint, Michigan, 48503, United States; Recruiting

Susumu Inoue, MD 810-762-7303 sinoue1@hurleymc.com

Josephine Ford Cancer Center at Henry Ford Health System, Detroit, Michigan, 48202,
United States; Recruiting
Hassan M. Yaish, MD 313-916-3138

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, 48109-0914,

United States; Recruiting
Raymond J. Hutchinson, MD 734-936-8785
 Van Elslander Cancer Center at St. John Hospital and Medical Center, Detroit, Michigan,
48236, United States; Recruiting
Hadi Sawaf, MD 313-647-3200 hadi.sawaf@stjohn.org

William Beaumont Hospital - Royal Oak, Royal Oak, Michigan, 48073-6769, United
States; Recruiting
Charles A. Main, MD 248-551-0360

Minnesota
Children's Hospitals and Clinics - Minneapolis/St. Paul, Minneapolis, Minnesota, 55404,
United States; Recruiting
Maura C. O'Leary, MD 612-813-5940

Mayo Clinic Cancer Center, Rochester, Minnesota, 55905, United States; Recruiting
Carola A.S. Arndt, MD 507-284-2695 carndt@mayo.edu

St. Mary's - Duluth Clinic Cancer Center, Duluth, Minnesota, 55805, United
States; Recruiting
Jacquelyn Dawn Wiermaa, MD 218-786-3625

Mississippi
University of Mississippi Medical Center, Jackson, Mississippi, 39216-4505, United
States; Recruiting
Dale Jeanette Pullen, MD 601-984-5220

Missouri
Cardinal Glennon Children's Hospital, Saint Louis, Missouri, 63104, United
States; Recruiting
William Shay Ferguson, MD 314-577-5638

Children's Mercy Hospital, Kansas City, Missouri, 64108, United States; Recruiting
Maxine L. Hetherington, MD 816-234-3265

St. Louis Children's Hospital, Saint Louis, Missouri, 63110, United States; Recruiting
Robert James Hayashi, MD 314-454-4118 hayashi_r@kids.wustl.edu

University of Missouri - Columbia, Columbia, Missouri, 65203, United States; Recruiting

Barbara Anne Gruner, MD 573-882-3961 grunerb@health.missousri.edu

Nebraska
Children's Hospital of Omaha, Omaha, Nebraska, 68114, United States; Recruiting
Minnie Abromowitch, MD 402-955-3949 mabromo@unmc.edu

UNMC Eppley Cancer Center at the University of Nebraska Medical Center, Omaha,
Nebraska, 68198-2168, United States; Recruiting
Peter F. Coccia, MD 402-559-7257 pcoccia@unmc.edu
Nevada
Sunrise Hospital and Medical Center, Las Vegas, Nevada, 89109, United States; Recruiting
Jonathan Bernstein, MD 702-732-0971 jonbern1@aol.com

New Hampshire
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon, New
Hampshire, 03756, United States; Recruiting
Eric Christian Larsen, MD 603-650-5541 eric.c.larsen@hitchcock.org

New Jersey
Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey, 07601,
United States; Recruiting
Michael B. Harris, MD 201-996-5437 mbharris@humed.com

Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School, New
Brunswick, New Jersey, 08903, United States; Recruiting
Richard A. Drachtman, MD 732-235-5437 drachtri@umdnj.edu

Newark Beth Israel Medical Center, Newark, New Jersey, 07112-2094, United
States; Recruiting
Peri Kamalakar, MD 973-926-7161 pkamalak@sghcs.com

St. Joseph's Hospital and Medical Center, Paterson, New Jersey, 07503, United
States; Recruiting
Mary Ann Bonilla, MD 973-754-3230 bonillam@sjhmc.org

Valerie Fund Children's Center at Atlantic Health, Summit, New Jersey, 07901, United
States; Recruiting
Hazem Helmy Mahmoud, MD 973-971-6731

New Mexico
University of New Mexico Cancer Research and Treatment Center, Albuquerque, New
Mexico, 87131, United States; Recruiting
Jami Frost, MD 505-272-4461

New York
Albert Einstein Cancer Center at Albert Einstein College of Medicine, Bronx, New York,
10461, United States; Recruiting
Eva Radel, MD 718-920-7844

Brookdale University Hospital and Medical Center, Brooklyn, New York, 11212, United
States; Recruiting
Kusum Viswanathan, MD 718-240-5904

Brooklyn Hospital Center, Brooklyn, New York, 11201-5493, United States; Recruiting
Swayamprabha Sadanandan, MD 718-250-6074 sws9001@nyp.org

Cancer Center of Albany Medical Center, Albany, New York, 12208, United
States; Recruiting
Jennifer M. Pearce, MD 518-262-5513 pearcej@mail.amc.edu

Comprehensive Cancer Center at Maimonides Medical Center, Brooklyn, New York,

11219, United States; Recruiting
Ludovico Guarini, MD 718-283-8173 lguarini@maimonidesmed.org

Herbert Irving Comprehensive Cancer Center at Columbia University, New York, New
York, 10032, United States; Recruiting
Linda Granowetter, MD 212-305-8652 lg519@columbia.edu

James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester, New
York, 14642, United States; Recruiting
Barbara Lawrence Asselin, MD 716-275-2981

Long Island Cancer Center at Stony Brook University Hospital, Stony Brook, New York,
11794, United States; Recruiting
Robert Ingalls Parker, DSc 631-444-4000

Memorial Sloan-Kettering Cancer Center, New York, New York, 10021, United
States; Recruiting
Peter G. Steinherz, MD 212-639-7951

Mount Sinai School of Medicine, New York, New York, 10029, United States; Recruiting
Elizabeth Raetz, MD 212-241-7022

New York Medical College, Valhalla, New York, 10595, United States; Recruiting
M. Fevzi Ozkaynak, MD 914-493-7997 mehmet_ozkaynak@nymc.edu

New York Weill Cornell Cancer Center at Cornell University, New York, New York, 10021,
United States; Recruiting
Patricia J.V. Giardina, MD 212-746-3400

Schneider Children's Hospital, New Hyde Park, New York, 11042, United
States; Recruiting
Arlene Sara Redner, MD 718-470-3460

SUNY Downstate Medical Center, Brooklyn, New York, 11203, United States; Recruiting
Sreedhar P. Rao, MD 718-270-1693

SUNY Upstate Medical University Hospital, Syracuse, New York, 13210, United
States; Recruiting
Ronald L. Dubowy, MD 315-464-5294 dubowyr@upstate.edu

North Carolina
Blumenthal Cancer Center at Carolinas Medical Center, Charlotte, North Carolina, 28232-
2861, United States; Recruiting
Daniel P. McMahon, MD 704-355-1130 dmcmahon@carolinas.org
 Comprehensive Cancer Center at Wake Forest University, Winston Salem, North Carolina,
27157-1081, United States; Recruiting
Thomas Williams McLean, MD 336-716-4324

Duke Comprehensive Cancer Center, Durham, North Carolina, 27710, United

States; Recruiting
Philip Paul Breitfeld, MD 919-684-3377

Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital, Greenville, North
Carolina, 27858-4354, United States; Recruiting
Charles W. Daeschner, MD 252-744-4676 DaeschnerC@mail.ecu.edu

Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel

Hill, Chapel Hill, North Carolina, 27599, United States; Recruiting
Stuart Gold, MD 919-966-0985 stubaby@med.unc.med

Mission Hospitals, Asheville, North Carolina, 28801, United States; Recruiting

Orren Beaty, DO, PhD 823-213-5770 orren.beaty@msj.org

Presbyterian Cancer Center at Presbyterian Hospital, Charlotte, North Carolina, 28233,

United States; Recruiting
Mark Mogul, MD 704-384-1900

North Dakota
Dakota Cancer Institute at Innovis Health - Dakota Clinic, Fargo, North Dakota, 58103-
4940, United States; Recruiting
Janet K. Tillisch, MD 701-364-4964

Ohio
Children's Hospital Medical Center of Akron, Akron, Ohio, 44308-1062, United
States; Recruiting
Steven J. Kuerbitz, MD 330-543-8730 skuerbitz@chmca.org

Children's Medical Center - Dayton, Dayton, Ohio, 45404, United States; Recruiting
Emmett H. Broxson, MD, FAAP 937-641-3111 broxsone@childrensdayton.org

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 45229-3039, United

States; Recruiting
John Peter Perentesis, MD 513-636-6090

Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, 44195, United States; Recruiting

Karen A. Bringelsen, MD 216-444-7923

Columbus Children's Hospital, Columbus, Ohio, 43205-2696, United States; Recruiting

Amanda Termuhlen, MD 614-722-3552
 Forum Health-Tod Childrens Hospital, Youngstown, Ohio, 44501, United
States; Recruiting
Ayman Saleh, MD, FAAP 330-884-3955 asaleh@neoucom.edu

Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve
University, Cleveland, Ohio, 44106-5065, United States; Recruiting
Susan Wiersma, MD 216-844-3345 srw3@po.cwru.edu

St. Vincent Mercy Medical Center, Toledo, Ohio, 43608, United States; Recruiting
Rama Jasty, MD 419-251-8215 rjasty@mco.edu

Toledo Children's Hospital, Toledo, Ohio, 43601, United States; Recruiting

Richard M. Shore, MD 419-471-5437

Oklahoma
CCOP - Oklahoma, Tulsa, Oklahoma, 74136, United States; Recruiting
James B. Lockhart, MD 918-491-5878

Children's Hospital at Oklahoma University Medical Center, Oklahoma City, Oklahoma,

73104, United States; Recruiting
William H. Meyer, MD 405-271-5311 william-meyer@ouhsc.edu

Natalie Warren Bryant Cancer Center at St. Francis Hospital, Tulsa, Oklahoma, 74136,
United States; Recruiting
Martina Christine Hum, MD 918-494-2525 pedonc@saintfrancis.com

Oregon
CCOP - Columbia River Oncology Program, Portland, Oregon, 97225, United
States; Recruiting
Keith S. Lanier, MD 503-216-6260

Doernbecher Children's Hospital at Oregon Health & Science University, Portland, Oregon,
97239-3098, United States; Recruiting
H. Stacy Nicholson, MD, MPH 503-494-1543

Legacy Emanuel Hospital and Health Center & Children's Hospital, Portland, Oregon,
97227, United States; Recruiting
Janice Faye Olson, MD 503-413-2200

Pennsylvania
Children's Hospital at Milton S. Hershey Medical Center, Hershey, Pennsylvania, 17033,
United States; Recruiting
John E. Neely, MD 717-531-6012 jen6@psu.edu

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, 19104, United

States; Recruiting
Richard Berry Womer, MD 215-590-2229 rwomer@mail.med.upenn.edu
 Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, 15213, United
States; Recruiting
Arthur Kim Ritchey, MD 412-692-5055 kim.ritchey@chp.edu

Geisinger Medical Center, Danville, Pennsylvania, 17822-1320, United States; Recruiting

Jeffrey Taylor, MD 570-271-6848

St. Christopher's Hospital for Children, Philadelphia, Pennsylvania, 19134-1095, United

States; Recruiting
Gregory E. Halligan, MD 215-427-5000 Gregory.Halligan@tenethealth.com

Rhode Island
Rhode Island Hospital, Providence, Rhode Island, 02903, United States; Recruiting
Sam W. Lew, MD 401-444-5171

South Carolina
Children's Hospital of Greenville Hospital System, Greenville, South Carolina, 29605,
United States; Recruiting
Cary Ernest Stroud, MD 864-455-8898

Hollings Cancer Center at Medical University of South Carolina, Charleston, South

Carolina, 29425-0721, United States; Recruiting
Julio C. Barredo, MD 843-792-2957 barredjc@musc.edu

Palmetto Health South Carolina Cancer Center, Columbia, South Carolina, 29203, United
States; Recruiting
Ronnie W. Neuberg, MD 803-434-3533 ronnie.neuberg@palmettohealth.org

South Dakota
Avera Cancer Institute, Sioux Falls, South Dakota, 57105-1080, United States; Recruiting
Marwan D. Hanna, MD 605-322-7595

Sioux Valley Hospital and University of South Dakota Medical Center, Sioux Falls, South
Dakota, 57117-5039, United States; Recruiting
Jakica Tancabelic, MD 605-333-7171 jtancabe@usd.edu

Tennessee
East Tennessee Children's Hospital, Knoxville, Tennessee, 37901, United States; Recruiting

Ray C. Pais, MD 865-541-8266 hemonc@etch.com

East Tennessee State University Cancer Center at Johnson City Medical Center, Johnson
City, Tennessee, 37614-0622, United States; Recruiting
David K. Kalwinsky, MD 423-433-6200 sjcrhta@msha,cin

St. Jude Children's Research Hospital, Memphis, Tennessee, 38105-2794, United

States; Recruiting
Wayne Lee Furman, MD 901-495-3300
 Vanderbilt Children's Hospital, Nashville, Tennessee, 37232-6310, United
States; Recruiting
James A. Whitlock, MD 615-936-1762

Texas
Baylor College of Medicine, Houston, Texas, 77030, United States; Recruiting
C. Philip Steuber, MD 713-798-6970

CCOP - Scott and White Hospital, Temple, Texas, 76508, United States; Recruiting
Lucas Wong, MD 254-724-1053 lwong@swmail.sw.org

Center for Cancer Prevention and Care at Scott and White Clinic, Temple, Texas, 76508,
United States; Recruiting
Dick Suh, MD, PhD 254-724-9852 DSuh@swmail.sw.org

Children's Hospital of Austin, Austin, Texas, 78701, United States; Recruiting

Sharon K. Lockhart, MD 512-324-8480 slockhart@stcaustin.com

Cook Children's Medical Center - Fort Worth, Fort Worth, Texas, 76104, United
States; Recruiting
Timothy C. Griffin, MD 682-885-4020 TGriffin@cookchildrens.org

Covenant Children's Hospital, Lubbock, Texas, 79410, United States; Recruiting

John Iacuone, MD 806-725-4840

MBCCOP - South Texas Pediatrics, San Antonio, Texas, 78229-3900, United

States; Recruiting
Anne-Marie Langevin, MD 210-704-3405 langevin@uthscsa.edu

MD Anderson Cancer Center at University of Texas, Houston, Texas, 77030-4009, United

States; Recruiting
Joann Ater, MD 713-792-6665 jater@mdanderson.org

Medical City Dallas Hospital, Dallas, Texas, 75230, United States; Recruiting
Carl Lenarsky, MD 972-566-6647 carl.lenarsky@usoncology.com

Methodist Cancer Center at Methodist Specialty and Transplant Hospital, San Antonio,
Texas, 78229-3902, United States; Recruiting
Jaime Estrada, MD 210-575-8130

San Antonio Military Pediatric Cancer and Blood Disorders Center, Lackland Air Force
Base, Texas, 78236, United States; Recruiting
Aaron Pitney, MD 210-292-5684

Simmons Cancer Center at University of Texas Southwestern Medical Center -

Dallas, Dallas, Texas, 75390-9063, United States; Recruiting
Naomi J. Winick, MD 214-648-3074 naomi.winick@utsouthwestern.edu
 Texas Tech University Health Sciences Center School of Medicine, Amarillo, Texas,
79106, United States; Recruiting
Curtis Wade Turner, MD 806-354-5434 curtis.turner@ttuhsc.edu

University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78207,
United States; Recruiting
Paul Jan Thomas, MD 210-704-3405 thomasp@uthscsa.edu

University of Texas Medical Branch, Galveston, Texas, 77555-0209, United

States; Recruiting
Frederick Szujuei Huang, MD 409-772-2341 fshuang@utmb.edu

Utah
Huntsman Cancer Institute at University of Utah, Salt Lake City, Utah, 84112, United
States; Recruiting
Carol S. Bruggers, MD 801-585-0303

Vermont
Vermont Cancer Center at University of Vermont, Burlington, Vermont, 05401-3498,
United States; Recruiting
Alan C. Homans, MD 802-847-2850

Virginia
Cancer Center at the University of Virginia, Charlottesville, Virginia, 22908, United
States; Recruiting
Kimberly Dunsmore, MD 434-924-9333

Carilion Medical Center for Children at Roanoke Community Hospital, Roanoke, Virginia,
24029, United States; Recruiting
Joan Mistretta Fisher, MD, PhD 540-985-8055 jmfisher@carilion.com

Children's Hospital of the King's Daughters, Norfolk, Virginia, 23507, United

States; Recruiting
Rebecca L. Byrd, MD 757-668-7243 byrdrl@chkd.org

INOVA Fairfax Hospital, Falls Church, Virginia, 22042-3300, United States; Recruiting
Jay N. Greenberg, MD 703-698-1110

Massey Cancer Center at Virginia Commonwealth University, Richmond, Virginia, 23298-

0121, United States; Recruiting
Nancy L. Dunn, MD 804-828-9605 nldunn@hsc.vcu.edu

Naval Medical Center, Portsmouth, Portsmouth, Virginia, 23708-5100, United

States; Recruiting
Paulette Charese Bryant, MD 804-398-5767

Washington
 Children's Hospital and Regional Medical Center - Seattle, Seattle, Washington, 98105,
United States; Recruiting
Douglas Hawkins, MD 206-987-3096

Deaconess Medical Center, Spokane, Washington, 99210-0248, United States; Recruiting

Steven K. Bergstrom, MD 509-473-7012 bergst@empirehealth.org

Fred Hutchinson Cancer Research Center, Seattle, Washington, 98109-1024, United

States; Recruiting
Jean E. Sanders, MD 206-667-4348 jsanders@fhcrc.org

Group Health Central Hospital, Seattle, Washington, 98112, United States; Recruiting
Philip Herzog, MD 425-883-5291

Madigan Army Medical Center, Tacoma, Washington, 98431-0001, United

States; Recruiting
Kelly Faucette, MD 253-968-1305 kelly.faucette@nw.amedd.army.mil

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington, 98415-0299,
United States; Recruiting
William J. Thomas, MD 253-403-4915 hemonc@multicare.org

West Virginia
Cabell Huntington Hospital, Huntington, West Virginia, 25701, United States; Recruiting
Andrew Pendleton, MD 304-691-1384 dpendlet@marshall.edu

Mary Babb Randolph Cancer Center at West Virginia University Hospitals, Morgantown,
West Virginia, 26506-9300, United States; Recruiting
Frank G. Keller, MD 304-293-1217

West Virginia University - Robert C. Byrd Health Sciences Center - Charleston

Division, Charleston, West Virginia, 25302, United States; Recruiting
Elizabeth M. Kurczynski, MD 304-388-1540 ekurczynski@hsc.wvu.edu

Wisconsin
Bellin Memorial Hospital, Green Bay, Wisconsin, 54301, United States; Recruiting
Dorothy J. Ganick, MD 920-433-6025

CCOP - Marshfield Clinic Research Foundation, Marshfield, Wisconsin, 54449, United

States; Recruiting
Tarit Kumar Banerjee, MD, FACP 715-387-5511

CCOP - St. Vincent Hospital Cancer Center, Green Bay, Green Bay, Wisconsin, 54301,
United States; Recruiting
Thomas J. Saphner, MD 920-432-5134

Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center, La Crosse,

Wisconsin, 54601, United States; Recruiting
Robert S. Ettinger, MD 608-782-7300 rsetting@gundluth.org

Marshfield Clinic - Marshfield Center, Marshfield, Wisconsin, 54449-5772, United

States; Recruiting
Harlan James Nickerson, MD 715-387-5018

Midwest Children's Cancer Center, Milwaukee, Wisconsin, 53226, United

States; Recruiting
Bruce M. Camitta, MD 414-456-4106

St. Vincent Hospital, Green Bay, Wisconsin, 54307-9070, United States; Recruiting
Jon Brandt, MD 920-433-8670

University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, 53792-6164,

United States; Recruiting
Diane Puccetti, MD 608-263-0320

Australia, New South Wales

Children's Hospital at Westmead, Westmead, New South Wales, 2145, Australia; Recruiting

Geoffrey McCowage, MD 61-2-9845-2122

Sydney Children's Hospital, Randwick, New South Wales, 2031, Australia; Recruiting
Glenn Marshall, MD, MBBS 61-2-9382-1721 g.marshall@unsw.edu.au

Australia, Queensland
Royal Children's Hospital, Brisbane, Queensland, 4029, Australia; Recruiting
Liane Lockwood, MBBS, FRACP 617-363-61356 liane_lockwood@health.gld.gov.au

Australia, South Australia

Women's and Children's Hospital, North Adelaide, South Australia, 5006,
Australia; Recruiting
Maria Louis Kirby, MBBS, FRACP 61-8-8161-7411 kirbym@mail.wch.sa.gov.au

Australia, Victoria
Royal Children's Hospital, Parkville, Victoria, 3052, Australia; Recruiting
David Ashley, MBBS, FRACP, PhD 61-39-345-5522

Australia, Western Australia

Princess Margaret Hospital for Children, Perth, Western Australia, 6001,
Australia; Recruiting
David L. Baker, MD, MBBS, FRACP, FRCPA 61-8-9340-8234

Canada, Alberta
Alberta Children's Hospital, Calgary, Alberta, T2T 5C7, Canada; Recruiting
Douglas R. Strother, MD 403-943-7272

Cross Cancer Institute, Edmonton, Alberta, T6G 1Z2, Canada; Recruiting

Paul Edward Grundy, MD 780-432-8894 pgrundy@cha.ab.ca

Canada, British Columbia

British Columbia Children's Hospital, Vancouver, British Columbia, V6H 3V4,
Canada; Recruiting
Paul C.J. Rogers, MB, ChB, FRCPC, MBA, FRCP 604-875-2322 progers@cw.bc.ca

Canada, Manitoba
CancerCare Manitoba, Winnipeg, Manitoba, R3E 0V9, Canada; Recruiting
Rochelle A. Yanofsky, MD 204-787-4163 rochelle.yanofsky@cancercare.mb.ca

Canada, Newfoundland and Labrador

Janeway Children's Health and Rehabilitation Centre, St. John's, Newfoundland and
Labrador, A1B 3V6, Canada; Recruiting
John (Jack) Hand, MD 709-777-4799 hcc.hanjg@hccsj.nf.ca

Canada, Nova Scotia

IWK Health Centre, Halifax, Nova Scotia, B3J 3G9, Canada; Recruiting
Dorothy R. Barnard, MD 902-470-8291 dorothy.barnard@iwk.nshealth.ca

Canada, Ontario
Children's Hospital of Eastern Ontario, Ottawa, Ontario, K1H 8L1, Canada; Recruiting
Jacqueline Halton, MD 613-737-7600 ext. 2370

Children's Hospital of Western Ontario, London, Ontario, N6C 2V5, Canada; Recruiting
Anne Elizabeth Lois Cairney, MD 519-685-8494 beth.cairney@lhsc.on.ca

Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada; Recruiting
Alberto S. Pappo, MD 416-813-6594 alberto.pappo@sickkids.ca

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario, L8N 3Z5,
Canada; Recruiting
Ronald D. Barr, MD 905-521-2100 ext. 73464 rbarr@mcmaster.ca

Canada, Quebec
Centre de Recherche du Centre Hospitalier de l'Universite Laval, Sainte-Foy, Quebec, GIV
4G2, Canada; Recruiting
Yvan Samson, MD 418-656-4141

Hopital Sainte Justine, Montreal, Quebec, H3T 1C5, Canada; Recruiting

Albert Moghrabi, MD 514-345-4969 albert.moghrabi@umontreal.ca

Montreal Children's Hospital at McGill University Health Center, Montreal, Quebec, H3G
1A4, Canada; Recruiting
Carolyn R. Freeman, MB, BS, FRCPC 514-412-8040 carolyn.freeman@muhc.mcgill.ca

Canada, Saskatchewan
Allan Blair Cancer Centre at Pasqua Hospital, Regina, Saskatchewan, S4T 7T1,
Canada; Recruiting
Christina Ten Suan Goh, MD 306-766-2205 tgoh@scf.sk.ca

Saskatoon Cancer Centre, Saskatoon, Saskatchewan, S7N 4H4, Canada; Recruiting

Ali S. Kaiser, MD 306-655-2684

Netherlands
University Medical Center Groningen, Groningen, 9700 RB, Netherlands; Recruiting
Willem A. Kamps, MD, PhD 31-50-361-4213 w.a.kamps@bkk.azg.nl

New Zealand
Starship Children's Health, Auckland, New Zealand; Recruiting
Lochie Teague, MD 64-9-307-4949 ext. 6295 lochiet@adhb.govt.nz

Puerto Rico
Puerto Rico Cancer Center at University of Puerto Rico - Medical Sciences Campus, San
Juan, 00936-5067, Puerto Rico; Recruiting
Nilka J. Barrios, MD 787-756-3230

San Jorge Children's Hospital, Santurce, 00912, Puerto Rico; Recruiting

Luis Antonio Clavell, MD 787-726-0316 luis.clavell@paviahealth.com

Switzerland
Swiss Pediatric Oncology Group Bern, Bern, CH 3010, Switzerland; Recruiting
Annette Ridolfi-Luethy, MD 41-31-632-9372

Swiss Pediatric Oncology Group Geneva, Geneva, CH 1211, Switzerland; Recruiting

Pierre Wacker, MD 41-22-382-3311

Swiss Pediatric Oncology Group Lausanne, Lausanne, CH 1011, Switzerland; Recruiting

Maja Beck Popovic, MD 41-21-314-3567

Donor Peripheral Stem Cell Transplantation in Treating Patients With Acute

Myeloid Leukemia, or Myeloproliferative Disorder.
RATIONALE: Peripheral stem cell transplantation may be able to replace
immune cells that were destroyed by chemotherapy used to kill cancer cells.
Sometimes the transplanted cells can make an immune response against the
body's normal tissues. Methotrexate and cyclosporine may prevent this from
happening.

PURPOSE: Phase I/II trial to study the effectiveness of donor peripheral stem cell
transplantation in treating patients who have acute myeloid leukemia, or myeloproliferative
disorder.
Fred Hutchinson Cancer Research Center, Seattle, Washington, 98104, United
States; Recruiting Ann Woolfrey, MD 206-667-4453

XK469R in Treating Patients With Refractory Hematologic Cancer.

RATIONALE: Drugs used in chemotherapy, such XK469R, work in different ways to stop
cancer cells from dividing so they stop growing or die.
PURPOSE: Phase I trial to study the effectiveness of XK469R in treating patients who have
refractory hematologic cancer.

Illinois
University of Chicago Cancer Research Center, Chicago, Illinois, 60637-1470, United
States; Recruiting
Wendy Stock, MD 773-834-8982

Texas
MD Anderson Cancer Center at University of Texas, Houston, Texas, 77030-4095, United
States; Recruiting
Francis J. Giles, MD 713-792-8217 fgiles@mdanderson.org