Module 8 Infection & Immunity

FIRST WEEK QUESTIONS MODULE 8: INFECTION & IMMUNITY NAME: 1. Which of the following is a FALSE statement for the bacteria structure a-each bacteria has consists of a protoplasm that enclosed by the cell envelope b-its cell wall can stand high internal pressure c-peptidoglycan of gram negative cell wall is thinner between 15-20% d-cytoplasmic membrane is thin, elastic, semipermeable 2. Which of the followings are suitable in describing the fimbriae or the pili I-long filamentous II-thinner III-hair like projections IV-has two types which are the regular pili and sex pili a-I, II, III only b-II,III,IV only c-I and II only D-II and III only 3. [It is best to grow in the presence of relatively high concentration of carbon dioxide] the characteristic of the bacteria above can be classified into :a-obligatory aerobes b-facultative anaerobes c-obligatory anaerobes d-micro-aerophilics 4. Which of the following is related to lag phase in bacteria growth curve? a-there is an active multiplication b-the bigger the size of the inoculum the shorter the lag phase c-the rate of division become less and the rate of death is increased d-has a development of unfavourable pH and oxygen consumption 5. What are the bacteria that has a pili and helps in mediating the attachment to urinary tract epithelium? a-neisseria gonorrhoea and E.coli b-strept viridans c-clostridium perfringens d-bordetella 6. Which of the followings are the characteristics of endotoxins? I-found only in gram negative II-converted to antigenic,non toxic toxoids III-no specific receptors are found on host cells IV-less toxic a-I and II B-II and III c-I ,II, and III d-I ,III, IV only

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Module 8 Infection & Immunity

7. How can we describe commensalism? a-the parasites derives the benefit without causing injury to their host b-close association between two different organism c-both host and parasites are so dependent on each other d-parasites are harmful to their host 8. These are the example of laboratory diagnosis of parasitic infections EXCEPT a-direct methods microscopical examination b-indirect methods c-arthropods d-molecular biological methods 9. Which of the following are FALSE statement regarding to general morphology of trematoda? a-pear shaped or elongate worms b-round worms c-beneath the cuticle are three layers of muscle fibres d-trematodes are essentially anaerobic 10. These are the important members of this subclass EXCEPT a-ascaris lumbricoides b-trichuris trichiura c-capillaria philippinensis D-trichinella spiralis 11. Which of the following is a FALSE statement for the bacteria structure a-each bacteria has consists of a protoplasm that enclosed by the cell envelope b-its cell wall can stand high internal pressure c-peptidoglycan of gram negative cell wall is thinner between 15-20% d-cytoplasmic membrane is thin, elastic, semipermeable 12. Which of the followings are suitable in describing the fimbriae or the pili I-long filamentous II-thinner III-hair like projections IV-has two types which are the regular pili and sex pili a-I, II, III only b-II,III,IV only c-I and II only D-II and III only 13. [It is best to grow in the presence of relatively high concentration of carbon dioxide] the characteristic of the bacteria above can be classified into :a-obligatory aerobes b-facultative anaerobes c-obligatory anaerobes d-micro-aerophilics

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Module 8 Infection & Immunity

14. Which of the following is related to lag phase in bacteria growth curve? a-there is an active multiplication b-the bigger the size of the inoculum the shorter the lag phase c-the rate of division become less and the rate of death is increased d-has a development of unfavourable pH and oxygen consumption 15. What are the bacteria that has a pili and helps in mediating the attachment to urinary tract epithelium? a-neisseria gonorrhoea and E.coli b-strept viridans c-clostridium perfringens d-bordetella 16. Which of the followings are the characteristics of endotoxins? I-found only in gram negative II-converted to antigenic,non toxic toxoids III-no specific receptors are found on host cells IV-less toxic a-I and II B-II and III c-I ,II, and III d-I ,III, IV only Parasitology: Medical Protoozology 17. What is protozoa? a. a vast collection of eukaryotes unicellular microorganisms of different sizes and forms, may be free-living or parasitic and capable of performing all functions of life due to present of organelles that resemble systems of large organisms. b. a limited collection of prokaryotes unicellular microorganism of same sizes and forms, maybe free-ling or parasitic and incapable of performing all functions of life due to absent of organelles that resemble systems of large organisms. c. a vast collection of eukaryotes multicellular microorganisms of different sizes and forms, maybe free-ling or parasitic and capable of performing all functions of life due to present of organelles resemble systems of large organisms. d. a vast collection of eukaryotes unicellular microorganisms of same sizes and forms, maybe free-living or parasitic and incapable of performing all functions of life due to absent of organelles resemble systems of large organisms. 18. Which of the following reproduces by syngamy? a. Leishmania b. Amoeba spp. c. Trichomonas vaginalis d. Sporozoa 19. Protozoa eats by one of the following means EXCEPT a. pseudopodia b. slit-like mouth peristome c. contractile vacuole d. diffusion by cell membrane

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Module 8 Infection & Immunity

20. All the following protozoa belong to its right habitat in the following matching EXCEPT a. Trypanosome blood & tissue b. Trichomonas vaginalis genitor-urinary tract c. Giardia lamblia digestive tract d. Plasmodia spp. central nervous system 21. Below are the important secretion of some protozoa EXCEPT a. histolytic enzymes b. antigenic materials c. cyst wall d. pigment granules Microbiology : Bacterial Genetics 22. Gene is the unit of heredity. What is the definition of gene? a. a segment of DNA and RNA that carries in its nucleotide sequence information for a specific biochemical and physiological properties. b. a segment of DNA that carries in its nucleotide sequence information for specific biological and psychological properties. c. a segment of DNA that carries in its nucleotide sequence information for a specific biochemical and physiological properties. d. full length of DNA strands that carries in its nucleotide sequence information for a specific biochemical and physiological properties. 23. Plasmid can code the following EXCEPT a. R factor b. bacteriocines c. toxin productions d. growth factors 24. Mutation can be induced by the following EXCEPT a. sporulation b. ultra-violet rays c. ethidium bromide d. ionizing radiation 25. Bacteria A received from Bacteria B a piece of DNA segment and cooperated within its own chromosome. This genetic transfer must be one of the following means EXCEPT a. Transformation b. Transposition c. Transduction d. Conjugation 26. Naturally competent transformable bacteria are found in the following species EXCEPT a. Neisseria gonorrhoeae b. Heamophilus influenza c. Streptococcus pneumonia d. Trichomonas vaginalis

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Module 8 Infection & Immunity

Community Medicine : Medical Terminology related to Infection 27. Bilharziasis is an _________ in Egypt. a. pandemic b. endemic c. epidemic d. academic 28. All the following are contagious diseases EXCEPT a. leprosy b. trachoma c. allergic dermatitis d. scabies 29. Communicable diseases could be transmitted by the following manners EXCEPT a. incubation b. directly c. indirectly d. vector 30. Influenza H1N1 (swine flu) is a type of a. pandemic b. endemic c. epidemic d. outbreak 31. Contamination could occur on or at the following objects EXCEPT a. clothes b. liver (kebda) c. water d. inanimate objects Pharmacology : Antibacterial Chemotherapy Classification and Instructions 32. All the following is the principles for the usage of antimicrobial drugs EXCEPT a. appropriate indication and dosage b. good knowledge of drugs pharmacokinetic and potential c. when to start treatment with suitable length of treatment period d. free mixed up of drugs and combinations 33. The following factors related to host effect the choice of the antimicrobial agent EXCEPT a. possibility to developing resistant b. host defense mechanisms c. drug allergy d. local factors

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Module 8 Infection & Immunity

34. which of the following is not drugs pharmacokinetic parameters? a. absorption b. osmolality c. volume distribution d. clearance 35. Which of the following is a misuse of antibiotic? a. incorrect indication b. change of causative pathogens c. treatment of untreatable virus infection d. inappropriate dosage 36. Combinations of antimicrobial drugs are for the following reasons EXCEPT a. empiric therapy b. polymicrobial infections c. to delay emergence if resistant strains d. to increase the dosage of drug for storage effect Microbiology: Mechanisms of Actions of Anti-Bacterial Agents 37. Which of the following drugs is a broad spectrum drug with biostatic function? a. tetracycline b. vancomycin c. trimethoprim d. chloramphenicol 38. Selective toxicity include the following EXCEPT a. attack special structures unique to bacteria b. damaging additional DNA structures such as plasmid and transposon c. targeting different subunit or composition of the shared structures between bacteria and mammals d. inhibiting metabolic pathways in bacteria that are different than mammals 39. What is the advantage of antibiotics that affect bacterial cell membrane? a. giving completely 100% no side effect to the host cells b. stop bacterial growth for a longer duration c. lethal even to non-growing cells d. induced host immune system 40. All the following are intracellular bacteria EXCEPT a. Chlamydia b. Rickettsia c. Brucella d. Leishmania 41. All the following quinolones have greater antibacterial activity and achieve potent systemic effect EXCEPT a. norfloxacin b. ofloxacin c. ciprofloxacin d. pefloxacin

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Module 8 Infection & Immunity

Pharmacology : -Lactam Antibiotics 42. -Lactam antibiotics share the following features EXCEPT a. mechanism of action b. mode of administration c. immunological characters d. clinical effects 43. All the following penicillins are the -Lactamase sensitive EXCEPT a. benzyl penicillin b. ticarcillin c. dicloxacillin d. ampicillin 44. Cephalosporins can be used for the following reasons EXCEPT a. infections resistant to penicillin b. patients sensitive to penicillin (mild allergy) c. Gram negative urinary tract infections & meningitis d. active against methicillin resistant staphylococcus aureus (MRSA) 45. Adverse effects of vancomycin are the following EXCEPT a. allergy hypersensitivity b. irritation leading to phetibitis at the site of infection c. ototoxicity and nephrotoxicity d. red man syndrome 46. All the following drugs work in combinations EXCEPT a. augmentin (ampicillin + clavulanic acid) b. impenem + rifampin c. penicillin G + probencid d. cotrimoxazole (sulphonamides + trimethoprim)

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Module 8 Infection & Immunity

ANSWERS 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. C D D B A D A C B A C D D B A D A D C D D C 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. D A B D B C A A B D A B C D A B C D A B C D A B

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