Drug

Classification

Action

Indications

Contraindications

Adverse Effects

Nursing Interventions

Tetanus Toxoid INJECTION (TET-un-us TOX-oid)

Tetanus vaccine

This medication is given to provide protection (immunity) against tetanus (lockjaw) in adults and children 7 years or older. Vaccination is the best way to protect against this life-threatening disease. Vaccines work by causing the body to produce its own protection (antibodies). Tetanus vaccine is usually first given to infants with 2 other vaccines for diphtheria and whooping cough (pertussis) in a series of 3 injections. This medication is usually used as a "booster" vaccine after this first series. Closely follow the vaccination schedule provided by the doctor.

For booster injection only for persons 7 years of age or older against tetanus. This vaccine is NOT indicated for primary immunization.

-Hypersensitivity to any component of the vaccine, including THIMEROSAL, and a MERCURY DERIVATIVE -Not for primary immunization. -A history of systemic allergic or neurologic reactions following a previous dose of Tetanus Toxoid

BODY AS A WHOLE: Redness warmth, edema Indurationwith or without tenderness as well as: urticaria rash Malaise transient fever,pain hypotension nausea arthralgia NERVOUS SYSTEM cochlear lesion brachial plexus neuropathies paralysis of the radial nerve paralysis of the recurrent nerve accommodation paresis Guillain-Barr syndrome EEG disturbances with encephalopathy

Before: >Postpone vaccination in patient with acute illness except in emergencies. >Determine Date of last tetanus immunization. During: >Be sure to know the age, duration and interval in giving TT After: >Instruct Patient to Report persistent or severe adverse reaction >Tell patient that nodule at injection site may be present for a few weeks >Advise patient for proper fever reducing drug dose for fever reaction

Drug

Classification

Action

Therapeutic Effects

Indications

Contraindications

Adverse Effects

Nursing Interventions

cefazolin Ancef, Kefzol

Cephalosporin antibiotic

Bind to bacterial cell wall membrane, causing cell death. Active against many gram-positive cocci including: Streptococcus pneumoniae, Group A beta-hemolytic streptococci; Penicillinasproducing staphylococci.

-Treatment of systemic infections caused by susceptible strains of microorganisms

-Patients with known allergy to the Cephalosporin group of antibiotics -Solutions containing dextrose may be contraindicated in patients with hypersensitivity to corn products.

CNS:Fever, seizure Dermatologic: Rash, pruritus, StevensJohnson syndrome Gastrointestinal: Diarrhea, nausea, vomiting, abdominal cramps, anorexia, pseudomembranous colitis, oral candidiasis Genitourinary: Vaginitis Hepatic: Transaminases increased, hepatitis Hematologic: Eosinophilia, neutropenia, leukopenia, thrombocytopenia, thrombocytosis Local: Pain at injection site, phlebitis Renal: BUN

Assess patient for infection (vital signs; appearance of surgical site, urine; WBC) at beginning and during therapy. Before initiating therapy, obtain a history to determine previous use of and reactions to penicillins or cephalosphorins. Persons with a negative history of penicillin sensitivity may still have an allergic response. Obtain specimens for culture and sensitivity before initiating therapy. Observe patient for signs and symptoms of anaphylaxis (rash, pruritis, laryngeal edema, wheezing). Discontinue drug and notify physician or other health care professional immediately if these problems occur. Keep epinephrine, an antihistamine, and resuscitation equipment close by in case of anaphylactic reaction. Monitor site for thrombophlebitis (pain, redness, swelling). Change sites every 48-72 hr to prevent phlebitis. Instruct patient to report