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RICHARD BAFFOUR, PHD Address: 13851 Belle Chasse Boulevard Unit 313, Laurel, Maryland 20707 Telephone Number:

240-264-8485 E-mail:

Intuitive, detail-oriented, and results-focused professional, with background in facilitating research and extension activities, including relevant experimental projects and results publication in attempts to develop an effective treatment for cardiovascular diseases. Reliable and solutions-focused leader, adept at con ducting initial research, data analysis, as well as viable solutions evaluation and development prior to integration into the market. Creative thinker, recogniz ed for innovative vision, high ethical standards, unsurpassed work ethic, and pr oven ability in communicating effectively across different management levels and diverse disciplines to build highly competent cross-functional teams. Skills Set: in vitro and in vivo Angiogenesis Organization / Process Improvement Resource Management Research and Examination Data Analysis, Evaluation, and Development Communication and Reporting Therapeutic Interventions Troubleshooting / Resolution of Issues Mentoring and Training

EDUCATION In Progress Doctor of Public Health CAPELLA UNIVERSITY ~ Online 19851988 Doctor of Philosophy in Cardiovascular Physiology in Experimental Surger y Division, FACULTY OF MEDICINE MCGILL UNIVERSITY ~ Montreal, Quebec, Canada 1982 1985 Master of Science in Physiology, FACULTY OF MEDICINE MCGILL UNIVERSITY ~ Montreal, Quebec, Canada 19681972 Bachelor of Science in Biochemistry and Nutrition UNIVERSITY OF GHANA ~ Accra, Legon, Ghana

CERTIFICATIONS The Science of Clinical Investigation, Johns Hopkins University, Schools of Medi cine and Public Health Design of Clinical Studies Ethical and Regulatory Issues in Clinical Research Outcomes and Effective Research Quantitative Analysis of Clinical Data

PROFESSIONAL EXPERIENCE 2011~Present Research Associate CARDIOVASCULAR RESEARCH INSTITUTE (CRI)~ Washington Hospital Center, District of

Columbia, USA Perform pre-clinical studies

19992011 Senior Scientist CARDIOVASCULAR RESEARCH INSTITUTE (CRI)~ Washington Hospital Center, District o f Columbia, USA Conducted independent and collaborative research in basic science, trans lation, and clinical studies in cardiovascular diseases, including research in b one marrow-derived stem cells used in treating patients with ischemic heart dise ase not amenable to current therapeutic interventions, such as surgery and endov ascular intervention Rendered efficient service in developing presentations at the national l evel and publications of research findings in peer review journals 19951997 Assistant Professor TUFTS UNIVERSITY, SCHOOL OF MEDICINE ~ Boston, Massachusetts, USA Applied superior knowledge and skills in accomplishing research and teac hing 19891997 Director, Surgical Research Laboratory BAYSTATE MEDICAL CENTER ~ Springfield, Massachusetts, USA Demonstrated exceptional performance in running a research laboratory, w hich led to several publications 19891994 Instructor TUFTS UNIVERSITY, SCHOOL OF MEDICINE ~ Boston, Massachusetts, USA Carried out independent research, facilitated training to technicians, a nd completed surgical residents that vastly contributed in the development of yo ung scientists 19881989 Research Assistant, Division of Cardiology MCGILL UNIVERSITY ~ Montreal, Quebec, Canada Demonstrated exceptional performance in producing a study on the effects of endothelin on coronary circulation in an isolated rabbit heart model 19831984 Demonstrator in Physiology MCGILL UNIVERSITY ~ Montreal, Quebec, Canada Provided effectual instruction to undergraduates in Physiology Laborator y 19741982 Research Technician III, Department of Surgery UNIVERSITY OF TORONTO ~ Toronto, Ontario, Canada Accomplished and published research on reperfusion injury in an acute is chemic model of rabbit heart 19721974 Assistant Biochemist, Department of Biochemistry KORLE BU TEACHING HOSPITAL, UNIVERSITY OF GHANA ~ Legon, Accra, Ghana Exemplified skills in studying routine clinical biochemistry and in rese arching sickle-cell anemia disease with particular reference to the effects of h emoglobin F to reduce the adverse effects of the disease

PAST AFFILIATIONS American Association for the Advancement of Science The New York Academy of Sciences

SELECTED PRESENTATIONS American College of Cardiology Annual Scientific Session, February 2006, Atlanta , Georgia, USA Bone Marrow-Derived Stem Cell Interactions with Adult Cardiomyocytes and Skeleta l Myoblasts in Culture, 941-48- 44A (Abstracts). American College of Cardiology Annual Scientific Session, March 1821, 2001 Orlando, Florida, USA Bone Marrow-Induced Stimulation of Endothelial and Smooth Muscle Cell Proliferat ion, Migration, Tube Formation, and Production of Growth Factors, 1078-187-232A (Abstracts). American College of Surgeons Annual Clinical Congress, October 1015, 1993 San Franc isco, California, USA Synergistic Effect of Basic Fibroblast Growth Factor and Methylprednisolone on N eurological Function After Experimental Spinal Cord Injury, J Neurosurg. 1995; 8 3:105-10.

PEER-REVIEWED PUBLICATIONS Waksman R, Baffour R, Pakala R, Scheinowitz M, Hellinga D, Seabron R, Chan R, Ko lodgie F, Virmani R. Effects of Exogenous Peripheral-Blood-Derived Endothelial Progenitor Cells or Unfractionated Bone-Marrow-Derived Cells on Neointimal Form ation and Inflammation in Cholesterol-Fed, Balloon-Denuded, and Radiated Iliac A rteries of Inbred Rabbits. Cardiovasc Revasc Med. 2009; 10:110-6. Waksman R, Pakala R, Roy P, Baffour R, Hellinga D, Seabron R, Chan R, Scheinowit z M, Kolodgie F, Virmani R. Effect of Clopidogrel on Neointimal Formation and In flammation in Balloon-Denuded and Radiated Hypercholest erolemic Rabbit Iliac Arteries. J Interv Cardiol. 2008; 21:122-8. Waksman R, Pakala R, Baffour R, Seabron R, Hellinga D, Tio FO. Short-Term Effect s of Biocorrodible Iron Stents in Porcine Coronary arteries. J Interv Cardiol. 2 008; 21:15-20. Waksman R, Pakala R, Baffour R, Hellinga D, Seabron R, Tio FO, Wittchow E, Titte lbach M, Diener T, Harder C, Virmani R, Jones R. Efficacy and Safety of Pimecrol imus-Eluting Stents in Porcine Coronary Arteries. Cardiovasc Revasc Med. 2007; 8 :259-74. Collins SD, Baffour R, Waksman R. Cell Therapy in Myocardial Infarction. Cardiov asc Revasc Med. 2007; 8:43-51. Review. Pakala R, Dilcher C, Baffour R, Hellinga D, Seabron R, Joner M, Kolodgie F, Virm ani R, Waksman R. Peroxisome Proliferator-Activated Receptor Gamma Ligand Piogli tazone Alters Neointimal Composition in a Balloon-Denuded and Radiated Hyperchol esterolemic Rabbit. J Cardiovasc Pharmacol. 2006; 48:299-305. Baffour R, Pakala R, Hellinga D, Joner M, Okubagzi P, Epstein SE, Waksman R. Bon e Marrow-Derived Stem Cell Interactions with Adult Cardiomyocytes and Skeletal M yoblasts in vitro. Cardiovasc Revasc Med. 2006; 7:222-30. Waksman R, Pakala R, Kuchulakanti PK, Baffour R, Hellinga D, Seabron R, Tio FO, Wittchow E, Hartwig S, Harder C, Rohde R, Heublein B, Andreae A, Waldmann KH, Ha verich A. Safety and Efficacy of Bioabsorbable Magnesium Alloy Stents in Porcine

Coronary Arteries. Catheter Cardiovasc Interv. 2006; 68: 607-17. Waksman R, Pakala R, Baffour R, Hellinga D, Seabron R, Kolodgie F, Virmani R. Op timal Dosing and Duration of Oral Everolimus to Inhibit In-Stent Neointimal Grow th in Rabbit Iliac Arteries. Cardiovasc Revasc Med. 2006; 7:179-84. Fuchs S, Kornowski R, Weisz G, Satler LF, Smits PC, Okubagzi P, Baffour R, Aggar wal A, Weissman NJ, Cerqueira M, Waksman R, Serrruys P, Battler A, Moses JW, Leo n MB, Epstein SE. Safety and Feasibility of Transendocardial Autologous Bone Mar row Cell Transplantation in Patients with Advanced Heart Disease. Am J Cardiol. 2006; 97:823-9. Waksman R, Fournadjiev J, Baffour R, Pakala R, Hellinga D, Leborgne L, Yazdi H, Cheneau E, Wolfram R, Seabron R, Horton K, Kolodgie F, Virmani R, Rivera E. Tran sepicardial Autologous Bone Marrow-Derived Mononuclear Cell Therapy in a Porcine Model of Chronically Infarcted Myocardium. Cardiovasc Radiat Med. 2004; 5:125-3 1. Pakala R, Kuchulakanti P, Rha SW, Cheneau E, Baffour R, Waksman R. Peroxisome Pr oliferator-Activated Receptor Gamma: Its Role in Metabolic Syndrome. Cardiovasc Radiat Med. 2004; 5:97-103. Review. Zhou YF, Stabile E, Walker J, Shou M, Baffour R, Yu Z, Rott D, Yancopoulos GD, R udge JS, Epstein SE. Effects of Gene Delivery on Collateral Development in Chro nic Hypoperfusion: Diverse Effects of Angiopoietin-1 Versus Vascular Endothelial Growth Factor. J Am Coll Cardiol. 2004; 44:897-903. Pakala R, Rha SW, Kuchulakanti PK, Cheneau E, Baffour R, Waksman R. Peroxisome P roliferator-Activated Receptor Gamma: Its Role in Atherosclerosis and Restenosis . Cardiovasc Radiat Med. 2004; 5:44-8. Review. Baffour R, Pakala R, Hellinga D, Seabron R, Fournadjiev J, Wolfram R, Okubagzi P , Epstein SE, Waksman R. Effects of Contrast Media on Porcine Bone Marrow-Deriv ed Mononuclear Cells and Calf Myoblast Viability and Secretion of VEGF and MCP-1 . Catheter Cardiovasc Interv. 2004; 62:476-81. Waksman R, Baffour R. Bone Marrow and Bone Marrow Derived Mononuclear Stem Cells Therapy for the Chronically Ischemic Myocardium. Cardiovasc Radiat Med. 2003;4: 164-8. Review. Stabile E, Zhou YF, Saji M, Castagna M, Shou M, Kinnaird TD, Baffour R, Ringel M D, Epstein SE, Fuchs S. Akt Controls Vascular Smooth Muscle Cell Proliferation i n vitro and in vivo by Delaying G1/S Exit. Circ Res. 2003; 93:1059-65. Fuchs S, Satler LF, Kornowski R, Okubagzi P, Weisz G, Baffour R, Waksman R, Weis sman NJ, Cerqueira M, Leon MB, Epstein SE. Catheter-Based Autologous Bone Marrow Myocardial Injection in No-Option Patients with Advanced Coronary Artery Diseas e: A Feasibility Study. J Am Coll Cardiol. 2003; 21.41:1721-4. Fuchs S, Baffour R, Vodovotz Y, Shou M, Stabile E, Tio FO, Leon MB, Kornowski R. Laser Myocardial Revascularization Modulates Expression of Angiogenic, Neuronal , and Inflammatory Cytokines in a Porcine Model of Chronic Myocardial Ischemia. J Card Surg. 2002; 17:413-24. Fuchs S, Baffour R, Shou M, Stabile E, Singh S, Schwartz B, Branellec D, Epstein SE, Kornowski R. Could Plasmid-Mediated Gene Transfer into the Myocardium Be Au gmented by Left Ventricular Guided Laser Myocardial Injury? Catheter Cardiovasc Interv. 2001; 54:533-8. Fuchs S, Baffour R, Stabile E, Kornowski R. Percutaneous Approach to Achieve The

rapeutic Myocardial Angiogenesis. Curr Interv Cardiol Rep. 2001; 3:192-197. Fuchs S, Shou M, Baffour R, Epstein SE, Kornowski R. Lack of Correlation Between Angiographic Grading of Collateral and Myocardial Perfusion and Function: Impli cations for the Assessment of Angiogenic Response. Coron Artery Dis. 2001; 12:17 3-8. Fuchs S, Baffour R, Zhou YF, Shou M, Pierre A, Tio FO, Weissman NJ, Leon MB, Eps tein SE, Kornowski R. Transendocardial Delivery of Autologous Bone Marrow Enhanc es Collateral Perfusion and Regional Function in Pigs with Chronic Experimental Myocardial Ischemia. J Am Coll Cardiol. 2001; 37:1726-32. Epstein SE, Fuchs S, Zhou YF, Baffour R, Kornowski R. Therapeutic Interventions for Enhancing Collateral Development by Administration of Growth Factors: Basic Principles, Early Results and Potential Hazards. Cardiovasc Res. 2001; 49:532-42 . Review. Baffour R, Garb JL, Kaufman J, Berman J, Rhee SW, Norris MA, Friedmann P. Angiog enic Therapy for the Chronically Ischemic Lower Limb in a Rabbit Model. J Surg R es. 2000; 93:219-29. Stark J, Baffour R, Garb JL, Kaufman J, Berman J, Rhee S, Norris MA, Friedmann P . Basic Fibroblast Growth Factor Stimulates Angiogenesis in the Hindlimb of Hype rglycemic Rats. J Surg Res. 1998; 79:8-12. Baffour R, Achanta K, Kaufman J, Berman J, Garb JL, Rhee S, Friedmann P. Synergi stic Effect of Basic Fibroblast Growth Factor and Methylprednisolone on Neurolog ical Function After Experimental Spinal Cord Injury. J Neurosurg. 1995; 83:105-1 0. Baffour R, Berman J, Garb JL, Rhee SW, Kaufman J, Friedmann P. Enhanced Angiogen esis and Growth of Collaterals by in vivo Administration of Recombinant Basic Fi broblast Growth Factor in a Rabbit Model of Acute Lower Limb Ischemia: Dose-Resp onse Effect of Basic Fibroblast Growth Factor. J Vasc Surg. 1992;16:181-91. Costello KB, Stewart DJ, Baffour R. Endothelin is a Potent Constrictor of Human Vessels Used in Coronary Revascularization Surgery. Eur J Pharmacol. 1990; 186:3 11-4. Petsikas D, Ricci MA, Baffour R, de Varennes B, Symes J, Guerraty A. Enhanced 24 -Hour in vitro Heart Preservation with Adenosine and Adenosine Monophosphate. J Heart Transplant. 1990; 9:114-8. Stewart DJ, Baffour R. Functional State of the Endothelium Determines the Respon se to Endothelin in the Coronary Circulation. Cardiovasc Res. 1990; 24:7-12. Graham AM, Baffour R, Burdon T, DeVarennes B, Ricci MA, Common A, Lisbona R, Sni derman AD, Symes JF. A Demonstration of Vascular Proliferation in Response to Ar teriovenous Reversal in the Ischemic Canine Hind Limb. J Surg Res. 1989; 47:3417. Ricci MA, Graham AM, Corbisiero R, Baffour R, Mohamed F, Symes JF. Are Free Radi cal Scavengers Beneficial in the Treatment of Compartment Syndrome After Acute A rterial Ischemia? J Vasc Surg. 1989; 9:244-50. Baffour R, Danylewick R, Burdon T, Sniderman A, Common A, Graham A, Symes JF. An Angiographic Study of Ischemia as a Determinant of Neovascularization in Arteri ovenous Reversal. Surg Gynecol Obstet. 1988; 166:28-32. Prickaerts JP, Wilson GJ, Bayliss CE, Baffour R. Influence of Fixative Osmolalit

y on the Morphometric Determination of Extracellular Space in Normal and Reperfu sed Ischaemic Myocardium. J Microsc. 1984; 135:169-9. Bayliss CE, Baffour R, Crawford FB. Myocardial Contracture: The Predominant Caus es of Impeded Reperfusion in Simulated Surgical Ischemia. Can J Surg. 1981; 24:2 60-4.