Drug Study

Generic Name Nacetylcysteine

Brand Name Solmucol

Classification Mucolytic

Dosage 600 mg / tab OD @ HS

Mechanism of Action Decreases viscosity of respiratory tract secretions and promote their removal by breaking disulfide bonds. In acetaminophen overdose, it protects the liver from injury by restoring glutathione levels or by acting as alternate substrate for acetaminophen metabolism

Indication Treatment of respiratory affections characterized by thick & viscous hypersecretions; acute &chronic bronchitis & its exacerbation, pulmonary emphysema, mucoviscidosis & bronchiectasis. Antidote in poisoning caused by paracetamol, carbon tetrachloride, arsenic, metallic mercury inhalation, yellow phosphorus & for cyclophosphamide induced hemorrhagic cystitis

Contraindication Hypersensitivity. Phenylketonuria(contai n aspartate)

Side effects Nausea,Vomiting , & other GI symptoms, generalized urticaria accompanied by mild fever, hypotension, wheezing, dyspnea,and stomatitis.

Nursing Implication -Instruct patient to follow directions exactly -Explain the importance of using drug as directed