Weary (adj) ( somewhat formal)

1. lacking strength, energy or freshness because of a need for rest or sleep

I need to rest my weary eyes

The miners were weary after a long shift

2. bored or annoyed by something because you have seen it, heard it, and/or done it
many times or for a long time

a) She was weary from years of housework.

b) She has grown weary of city life and moved out to the country.

Exhausted (adj) (common)

1. to use all of someone’s mental or physical energy

a) After working so many hours this week she was exhausted.

b) She collapsed on her bed, totally exhausted

Beat (adj) (informal) not used before a noun.

1. very tired, exhausted

a) I’m beat.
Burned out (adj) (common)

1. feeling very physically and emotionally tired after doing a difficult job for a long
time

a) I was burned out after working for 25 years as a nurse in ER.

Bushed ( adj) (informal) usually expresses physical fatigue

1. beat, exhausted,

a) The hike wore me out, I’m bushed

Drained ( adj) (common) used for emotional and physical fatigue

1. exhausted, very tired

a) I feel totally drained

Tired (adj) (common)

1. feeling a need to rest or sleep

a) I was really tired after the long trip.

Worn-out (adj) (common)

1. very tired, exhausted

a) The horses are worn out from the long ride

Done in (adj) (informal)

1. very tired

a) After working in the garden all day, I was completely done in.
Dead on their feet, dead tired, dead ( informal )

1. exhausted but still standing,working

a) By the end of the day the workers were dead on their feet.
b) She was dead tired.
c)

Pooped ( informal)

1. very tired

a) We were pooped after a long day of work.

Spent ( somewhat formal )

1. exhausted and drained of energy

a) By the end of the race I was completely spent

Wiped out ( informal/ colloquial)

1. extremely tired

a) I am completely wiped out.

Zonked (informal /colloquial) not that common

1. very tired

a) Chances are that I will be too zonked from the trip to go out tonight.
b) I’m zonked.