NURS 2516 Clinical Medications Worksheets

Generic Name Trade Name Classification Dose Route Time/frequency

ondansetron Zofran antiemetics 4 mg IVP Q 6 hr. PRN
Normal dose range: 4 mg before
induction of anesthesia or post-op
Peak Onset Duration For IV meds, compatibility with IV drips and /or solutions
15-30 min rapid 4 hr-8 hr Administer undiluted immediately before induction of anesthesia or
postoperatively if nausea and vomiting occur shortly after surgery
Rate: give over at least 30 sec and preferably over 2-5min
Mechanism of action and indications Nursing Implications (what to focus on)
(Why med ordered) Contraindications/warnings/interactions
Prevention of postoperative nausea and vomiting Hypersensitivity

Blocks the effects of serotonin at 5-HT3-receptor sites Common side effects

(selective antagonist) located in vagal nerve terminals and the
Headache, constipation, diarrhea
chemoreceptor trigger zone in the CNS
Interactions with other patient drugs, OTC or herbal Lab value alterations caused by medicine
medicines (ask patient specifically) May cause transient ↑ in serum bilirubin, AST, and ALT levels
May be affected by drugs altering the activity of liver
enzymes Be sure to teach the patient the following about this
medication
Advise patient to notify health care professional immediately if
involuntary movement of eyes, face, or limbs occurs
Nursing Process- Assessment Assessment Evaluation
(Pre-administration assessment) Why would you hold or not give this Check after giving
Assess patient for nausea, vomiting, abdominal med? Prevention of post-op nausea and
distention, and bowel sounds prior to and Assess patient for extrapyramidal effects vomiting
following administration (involuntary movements, facial grimacing,
rigidity, shuffling walk, trembling of hands)