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CLINICAL FINDINGS :
CLINICAL FINDINGS Maxillary central incisors are frequently avulsed teeth , while lower jaw seldom affected Occurs in 7 to 9 years of age , when permanent incisors are erupting-loosely structured periodontal ligament surrounding erupting teeth provides minimal resistance to an extrusive force. Avulsion involves single tooth mostly Multiple avulsions occasionally encountered
Radiographic findings :
Radiographic findings Suspicion of bone fractures In primary dentition ,radiographs will often reveal that a suspected avulsion is actually an intrusion where the primary tooth is buried in the jaw
PATHOLOGY :
PATHOLOGY Divided into pulpal and periodontal reactions Healing reaction depend upon the extra alveolar and extra alveolar handling
PULPAL REACTIONS :
PULPAL REACTIONS Distinct pulpo-dentinal responses which can occur after immediate replantation have been classified Regular tubular reparative dentin Irregular reparative dentin with diminished tubular structures Irregular reparative dentin with encapsulated cells Irregular immature bone Regular lamellated bone or cementum Internal resorption Pulp necrosis
Slide 7:
Extensive pulpal changes could be obtained as early as 3 days after replantation . Damage observed in coronal part of the pulp. Signs of healing were seen within 2 weeks after replantation.
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Damaged tissue mesenchymal cells and capillaries In border zone between vital and necrotic tissue , neutrophils and round cells were present in some cases
Slide 9:
The healing process led to the formation of new cell layer along the dentinal wall in the regions where the odontoblasts had been destroyed. New hard tissue formation along the dentinal walls was noted after 17 days , but it most cases matrix formation started somewhat later. Gradually the cells along the pup walls began to show similarities to odontoblasts with cytoplasmic processes within the newly formed matrix.
Slide 10:
Severe pulpal damage was more often found in teeth with completed root formation than in those with an open apex, where the pulpal repair seemed also to be more rapid. Mitoises were seen in bands of schwann cells 14 days after replantation. Regenerating nerve fibers were observed after 1 month.
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In microangoigraphic studies of the revascularization process after replantationof teeth in dogs ,it was demonstrated that in growth of new vessels could be seen 4 days after repalantation. After 10days vessels were seen in the apical half of the pulp and after 30 days in the entire pulp.
PERIODONTAL HEALING :
PERIODONTAL HEALING Coagulum is found between tow parts of severed periodontal ligament Line of separation is often situated in the middle of the periodontal ligament Proliferation of connective tissue cells soon occurs 3 to 4 days After 1 week the epithelium is reattached at the cemento enamel junction clinical importance , it may imply a reduced risk gingival infection and reduced risk of bacterial invasion
Slide 13:
After 2 weeks , the split line in the periodontal ligament is healed and collagen fibers are seen extending from the cemental surface to the alveolar bone . Resorption activity can now be recognized
Histological examination :
Histological examination Healing with normal healing Healing with surface resorption Healing with ankylosis (replacement resorption) Healing with inflammatory resorption
Slide 18:
Progressive resorption is elicted when the entire periodontal ligament is removed before replantation or after replantation. The ankylosed root becomes part of the normal bone remodelling system and is gradually replaced by bone . After some time , little of the tooth substance remains . At this stage the resorptive processes are usually intensified , along the surface of the root canal , a phenomenon known as tunneling resorption
Slide 19:
Radiographically disappearance of the normal periodontal space and continuous replacement of root substance with bone. Replacement resorption recognized radiographically 2 months after replantation ; however in most cases 6 months for 1 year elapses
Slide 20:
Clinically tooth is immobile and children frequently infraposition Percusion tone is high , differing clearly from adjacent tooth. In cases of TR - a small areas of periodontal ligament space has disappeared. Dis appearence always happens within the first year, is followed by the return of normal percussion.
Pathogenesis :
Pathogenesis Minor Injuries to the periodontal ligament and /or cementum due to trauma or contamination with bacterial induce small resorption cavities on the root surface , presumably in the same manner as in surface resorption. If these resorption cavities expose dentinal tubules and the root canal contains infected necrotic tissue , toxins from these areas will penetrate along the dentinal tubules to the lateral periodontal tissues and provoke an inflammatory response. This in turn will intensify the resorption process which advances towards the root canal. The resorption process can progressively very rapidly ie. Within a few months the entire root can be resorbed.
Slide 23:
Inflammatory resorption is especially frequent and aggressive after replantation in patients from 6 to 10 years of age. The explanation for this probably a combination of wide dentinal tubules and /or a the protective cementum cover. In older age groups , the resorption process is allowed to progress and involve large areas of the root surface , replacement resorption can take over inflammatory resorption has been arrested by endodontic therapy.
Slide 24:
Radiographically , inflammatory resorption is characterized by radiolucent bowl shaped cavitations along the root surface with corresponding excavations in the adjacent bone . the first radiographic sign inflammatory resorption can be demonstrated as early as 2 weeks after replantation and usually first recognized at the cervical third of the root. As in the case ankylosis , this resorption type is usually evident within the first 2 years after replantation. Clinically , the replanted tooth is losse and extruded. Moreover t tooth is sensitive to percussion and percussion tone is dull.
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Treatment of the Avulsed tooth
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Case history -time interval between injury and replantation as well as the conditions which the tooth has been stored. (eg , saline , saliva, milk, tap water, or dry ) Periodontal healing of replanted dog teeth stored in milk and egg albumen(dental traumatolgy 2009 Commercial tissue culture medium(viaspan) could be used for extra oral storage.
Slide 27:
Examination for surface contaminants Examination of alveolus Pre treatment radiograph
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Careful planning is of outmost important for the success of replantation of avulsed teeth. Following conditions should be considered - should be advanced periodontal disease socket should be reasonably intact - extra alveolar period should be considered ie. Extra alveolar period exceeding 1 hour are usually associated with marked root resorption .
Rigid splinting increases the extent of root resorption (acta odontol scand 1975, 1981) Replanted teeth should , therefore only splinted for one week to ensure adequate periodontal support , as gingival fibers are already healed by this time.
therapy is initiated and calcium hydroxide introduced to eliminate the periapical inflammation and arrest root resorption . After a week endodontic procedure is proceeded
Slide 34:
The incorporation of fluoride ions in the cementum layer has been found to yeaild a root surface resistant to resorption. It has been suggested that mature teeth with prolonged dry extra alveolar periods (ie greater then 1 hour ) be placed in a fluoride (2.4% of sodium flouride) at ph 5.5 solution for 20 minutes prior to replantation Thereafter the root surface is rinsed with saline and the tooth replanted and splinted for 6 weeks . the effect of this treatment seems to be 50% reduction of the progression of root resorption of replanted human teeth
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Oooooooooooooouch! Resorption of root ?
Tooth survival :
Tooth survival In long term study , it was shown tooth survival was significantly related to the stage of root development at the time of injury, being more favourable with increasing developmental maturity
pulps of teeth with incomplete root formation can become revascularized if replantation is carried out within 3 hours .pulpal sensibility test are unrelaile immediately after replanatation. Functional repair of pulpal nerve fibers in human teeth is established approximately 35 days after replantation . at this time electrical stimuli can elicit sensibility responses. In the absence of a reaction to electrical stimulation , it should be borne in mind that a decrease in the size of the coronal part of the pulp chamber or root canal on the radiograph is a more reliable sign of vital pulp tissue thermal or electrical pulp testing The most significant predictors of pulpal healing appear to be the width and length and type of extra alveolar storage .
Slide 46:
The best media tested during research in descending order were ViaSpan, Eagles Medium, and Hanks Balanced Salt Solution HBSS). Despite the fact that ViaSpan and Eagles Medium provide the best storage environment, these media are not practical options. These media are not readily available to school nurses and are not packaged for individual uses. Despite the time advantages, these media may be cost prohibitive when compared to other options available, for example, ViaSpan is $600 a gallon.
Slide 47:
HBSS has unquestionably been the most tested solution. Of the other suggested solutions (see chart 1), the options that provide acceptable storage have limited availability and the options that are readily available are either far inferior to HBSS or are actually damaging to the PDL cells. 0.9% normal sterile saline has a compatible osmolality with the PDL
cells,but does not contain any nutrients to help maintain cell vitality. Therefore, sterile saline is only good as a short-term storage medium for avulsed teeth and should not be used if the tooth cannot be reimplanted within 1 hour.
Slide 48:
Milk has a compatible osmolalty with the PDL cells of an avulsed tooth and has been tested as effective to store teeth for no more than 2-3 hours. Milk does not contain the necessary nutrients to maintain the PDL cells for any longer periods of time. Additionally, there are issues related to the practicality of using milk that severely impact its efficacy. Milk sounds, like an easy, inexpensive method for storage, however, using milk is not as effective as other media available and is logistically more difficult than other, more effective options. For example, if a child avulses a tooth on a remote sports playing field no milk will be readily available. Additionally, the milk needs to be kept refrigerated during transport for the best prognosis. Therefore, a school nurse should have a storage media that can be located at the scene of any accident.
Slide 49:
There is another commercially available product marketed for the storage of avulsed teeth called EMT ToothSaver, which contains antibiotic-free protective medium. EMT ToothSaver has not been tested for efficacy and does not have FDA approval nor the ADA Seal of Acceptance. The compatibility of EMT ToothSaver cannot be known without research testing and therefore, this media cannot be recommended.
Slide 50:
Like water, saliva is not compatible with the PDL cells. In addition to the damage the saliva can cause to the cells, saliva also contains bacteria that can cause the PDL cells to become infected. Therefore, it is not recommended to store teeth in neither a cup with saliva nor in the mouth of the victim or another person.
Slide 51:
There have been some recommendations to use tap water with a pinch of salt. Some believes this recommendation to be a misunderstanding of what HBSS and sterile saline are. HBSS is not a saltwater solution, but a scientifically designed researched fluid that contains all of the essential metabolites and glucose necessary for maintenance of cells. Adding salt to water will create a solution that is damaging to PDL cells.
Slide 52:
HBSS is the authors recommendation for the optimal storage media for use in schools. HBSS, found in Save-A-Tooth has been tested for efficacy and is able to be kept in the school nurses office as well as at sporting events without temperature control methods. Hopefully, this article provides information that will enable a school nurse to select the best storage medium for avulsed teeth. This selection can significantly affect the ultimate prognosis for avulsed replanted teeth.
Slide 53:
it appears that CW may be better alternative to HBSS or milk in terms of maintaining PDL cell viability after avulsion and storage. (A quantitative analysis of coconut water: a new storage media for avulsed teeth )..Velayutham Gopikrishna MDSa, , , Toby Thomas MDSb and Deivanayagam Kandaswamy MDs (oooo 2008))
Slide 54:
Comparison of coconut water, propolis, HBSS, and milk on PDL cell survival. Gopikrishna V, Baweja PS, Venkateshbabu N, Thomas T, Kandaswamy D. (joe 2008)
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Viability of human fibroblasts in coconut water as a storage medium (IEJ-2009) Coconut water was worse than milk in maintaining human fibroblast cell viability.
indicated that the storage media more than the length of the extra alveolar period determine prognosis.
Inflammatory resorption :
Inflammatory resorption Can occur 3 months after replantation Related to presence of an infected pulp Arrest of resorptive process cab be achieved by appropriate endodontic therapy
Root development and disturbances in root growth Root growth Continued root development can occur especially if the pulp has become totally revascularized . However root development can continue despite pulp necrosis. root development is partially or completely arrested and the root canal becomes obliterated or bone and PDL can invade the pulp chamber which in some cases can lead to an ankylosis
Phantom roots :
Phantom roots A rare complication to avulsion of immature permanent teeth is the formation of an abnormal root structure at the site of tooth loss. The explanation for this appears to be that pulp tissue and Hertwigs epithelial root sheath remain in the alveolar socket after avulsion. These tissues resume their formative function after injury. New dentin is formed by the odontobalsts and the hertwigs epithelial root sheath initiates root development. A parallel to this is the tooth like structures occasionally formed when natal or neonatal teeth are extracted and dental papilla is left situ.
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Thank you